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Radioembolization Practice in North America Versus Europe: Results from a Global Survey.

PURPOSE: The Cardiovascular and Interventional Radiological Society of Europe (CIRSE) conducted an international survey on the real-life application of transarterial radioembolization (TARE). This sub-analysis of the complete survey evaluates intercontinental disparities in TARE practices. MATERIALS AND METHODS: A survey of 32 multiple-choice questions was distributed to CIRSE members between November and December 2022. The questions addressed steps of the TARE workflow, including treatment work-up, planning and dosimetry, intervention, follow-up and innovations. Responses were curated to rem…

Relative proportion and contrasting host preference of Culex pipiens biotypes across Europe.

BACKGROUND: The primary vector of West Nile virus (WNV) in Europe, Culex pipiens, has two morphologically identical but behaviorally and genetically distinct biotypes, here referred to as Pipiens and Molestus. Pipiens and Molestus, and their hybrids, are differentially distributed across Europe and display variable patterns of blood-feeding on birds and humans across the continent, but whether host choice correlates with host preference is unclear. METHODS: Samples of mosquitoes were collected and subsequently biotyped using real-time PCR, following which the relative proportions of each biot…

Early-onset colorectal cancer across Europe: Burden, mechanisms, and health-system implications.

The incidence of early-onset colorectal cancer (EOCRC), diagnosed in individuals under 50 years, is rising across Europe, presenting a growing public health challenge distinct from later-onset disease. This review synthesizes the European landscape, revealing a heterogeneous epidemiological mosaic characterized by stark regional disparities in incidence, mortality-to-incidence ratios, and temporal trends. These patterns are shaped by a transitioning continental 'exposome', that is, the cumulative, lifelong integration of dietary, metabolic, and microbial exposures, interacting with genetic sus…

Lower Frequency of Multiple Erythema Migrans Skin Lesions in Lyme Reinfections, Europe.

The erythema migrans (EM) skin lesion is the most common clinical manifestation of Lyme borreliosis. Information about EM in Lyme borreliosi … ,962] vs. 7.4% [769/10,427]; p = 0.002). None of the clinical manifestations of Lyme borreliosis in Europe will completely protect against EM developing in patients in the future. The reoccurrence of Lyme borreliosis manifested by multiple EM lesions is significantly less likely than for patients with no history of Lyme borreliosis.

MULTIPLE INFECTIONS IN CAIMAN LIZARDS (DRACAENA GUIANENSIS) IMPORTED INTO EUROPE FROM PERU.

All of the animals in a group of 58 juvenile caiman lizards (Dracaena guianensis) imported to Europe from a breeding farm in Peru presented, one after the other, with prostration, dyspnea, and anorexia. Six animals that died or were euthanized were examined by histopathology, PCR for the detection of ferlaviruses, adenoviruses, reoviruses (n = 3), and cryptosporidia, and virus isolation in cell culture (n = 4). The genomes of two virus isolates were sequenced by nanopore sequencing. Histopathology showed interstitial proliferative pneumonia, multifocal lymphocytic pancreatitis with acinar atro…

Anesthesia management for total robotic liver transplantation: Inaugural case series in Europe.

Robotic liver transplantation represents a cutting-edge technique that may surpass traditional open surgery. Nonetheless, it introduces unique anesthetic challenges, including extended pneumoperitoneum, restricted patient access, and a risk of undetected blood loss. This article describes an anesthetic approach and patient outcomes for the first four total robotic liver transplants performed at a tertiary university hospital in Portugal, along with inaugural procedures of their kind in Europe. We retrospectively analyzed surgical and anesthetic data from four patients who underwent total robot…

Molecular characterization of Streptococcus suis isolates recovered from diseased pigs in Europe.

Streptococcus suis is a major swine pathogen and zoonotic agent, causing important economic losses to the porcine industry. Here, we used ge … , epf, and sly, with variable presence across different genotypes. The high genetic diversity among European S. suis isolates highlights the importance of targeted antimicrobial use and flexible vaccine strategies. Rapid strain characterization is crucial for optimizing swine health management, enabling tailored interventions like the development of auto …

Векторная динамика, лежащая в основе нынешнего и будущего появления в Европе вирусов, передаваемых через " тика " .

Болезни, передаваемые через тик, представляют все большую угрозу для здоровья человека и животных в Европе, при этом вирус энцефалита, передаваемый через тикали, и вирус геморрагической лихорадки Крыма-Конго (CCFV), вектором которых являются, соответственно, иксодес рицинус и маржатум гиаломмы, становятся основными проблемами в области общественного здравоохранения. Способность клещей передавать патогены на множество носителей и поддерживать инфекцию на всех этапах жизни делает их высокоэффективными векторами. Вместе с тем многие аспекты экологии и векторной способности клещей по-прежнему недо

Совпадение в аннотации оригинала
Tick-borne diseases pose a growing threat to human and animal health in Europe, with tick-borne encephalitis virus (TBEV) and Crimean-Congo haemorrhagic fever virus (CCHFV), vectored by Ixodes ricinus and Hyalomma marginatum, respectively, emerging as primary public health concerns. The ability of ticks to transmit pathogens to multiple hosts and maintain in…

VACCELERATE Site Network: Real-time definition of clinical study capacity in Europe.

BACKGROUND: The inconsistent European vaccine trial landscape rendered the continent of limited interest for vaccine developers. The VACCELERATE consortium created a network of capable clinical trial sites throughout Europe. VACCELERATE identifies and provides access to state-of-the-art vaccine trial sites to accelerate clinical development of vaccines. METHODS: Login details for the VACCELERATE Site Network (vaccelerate.eu/site-network/) questionnaire can be obtained after sending an email to. Interested sites provide basic information, such as contact details, affiliation with infectious di…

Incidence of Lyme Borreliosis in Europe from National Surveillance Systems (2005-2020).

Background: Lyme borreliosis (LB) is the most common tick-borne disease in Europe. To inform European intervention strategies, including vaccines under development, we conducted a systematic review for LB incidence. Methods: We searched publicly available surveillance data reporting LB incidence in Europe from 2005 to 2020. Population-based incidence was calculated as the number of reported LB cases per 100,000 population per year (PPY), and high LB risk areas (incidence >10/100,00 PPY for 3 consecutive years) were estimated. Results: Estimates of LB incidence were available for 25 countries. …

Dystonia management across Europe within ERN-RND: current state and future challenges.

BACKGROUND: Since the first European-wide evaluation of dystonia management in 2016, several efforts have been made to improve dystonia-care. One of these was the development of the Dystonia Disease Group as a part of the European Reference Network for Rare Neurological Diseases (ERN-RND) that implemented several initiatives based on the recommendations made in 2016. AIM: To evaluate the current state of dystonia management across Europe. METHODS: Twenty-four countries were surveyed via 62 dystonia-experts from 44 ERN-RND-related centers. RESULTS: Dystonia-experts for adult patients were av…

Epidemiological Trends of Trans-Boundary Tick-Borne Encephalitis in Europe, 2000-2019.

Tick-borne encephalitis is a neuroinfection widely distributed in the Euro-Asia region. Primarily, the virus is transmitted by the bite of infected ticks. From 2000-2019, the total number of confirmed cases in Europe reported to the European Centre for Disease Prevention and Control was 51,519. The number of cases decreased in 2014 and 2015; however, since 2015, a growing number of cases have been observed, with the involvement of countries in which TBE has not been previously reported. The determinant factors for the spread of TBE are host population size, weather conditions, movement of host…

Assisted peritoneal dialysis across Europe: Practice variation and factors associated with availability.

BACKGROUND: In Europe, the number of elderly end-stage kidney disease patients is increasing. Few of those patients receive peritoneal dialysis (PD), as many cannot perform PD autonomously. Assisted PD programmes are available in most European countries, but the percentage of patients receiving assisted PD varies considerably. Hence, we assessed which factors are associated with the availability of an assisted PD programme at a centre level and whether the availability of this programme is associated with proportion of home dialysis patients. METHODS: An online survey was sent to healthcare p…

Scurvy, Starvation, and Flea Infestation - A Case Report From 21st Century Europe.

Scurvy is a disease caused by vitamin C deficiency, historically associated with long sea voyages, periods of famine and war. Currently, it is often misdiagnosed and underreported, as physicians tend to consider it a disease of the past. We present the case of a 79-year-old female who was admitted to the Emergency Department complaining of pruritus. The patient lived alone and in poor hygiene conditions. Diet was scarce. One week before admission she was in contact with flea-ridden stray dogs. Sometime later she noted several fleas and multiple pruritic small papules, crusts, and excoriations

Skin melanoma deaths within 1 or 3 years from diagnosis in Europe.

The steep increase in incidence of cutaneous malignant melanoma in white populations mainly applies to thin lesions with good survival suggesting overdiagnosis. Based on population-based cancer registries (CRs), we have investigated changes in aggressive melanoma, selecting only cases who died within 1 or 3 years after diagnosis in 11 European countries between 1995 and 2012. Trends in fatal cases were analysed by period of diagnosis, sex, tumour thickness, histologic subtype of the lesion, tumour site and CR with a multivariate generalised linear mixed effects model, where geographical area w…