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[Axial mesenchyme structure in the anlage of the human vertebral column. Light microscopy study of a human embryo of 9 mm CRL (Carnegie stage 16)].

The anlage of the cervical vertebral column of a human embryo has been investigated (9 mm CRL, Carnegie stage 16). The nuclear density in the axial mesenchyme increases rhythmically from cranial to caudal. This phenomenon superimposes a metameric pattern on the blastema. Furthermore, cell formations are shaped by the orientation of the mesenchymal cells. The name 'formationes quasi distensae' is proposed for this system. The anlage of the atlas shows a distinct mesenchymal anlage of a vertebral body. The conclusion is drawn that the dens axis is predominantly formed out of the anlage of the at…

Assessment of Bilateral Pedicle Root Puncture Vertebral Fissure Expansion Percutaneous Kyphoplasty for the Treatment of Kümmell Disease.

STUDY DESIGN: Retrospective analysis of clinical efficacy. OBJECTIVE: To assess the clinical efficacy of bilateral pedicle root puncture ve … a balloon was used to expand the vertebral fissure at the interface between the fissure within the vertebral body and the adjacent cancellous bone, facilitating the anchoring of bone cement at this junction. This allowed for the diffusion of cement into the fissure cavity and surrounding areas. Surgical outcomes were systematically observed and documented, incl …

[Computerized tomography imaging of the lumbar spine in arthroosteitis pustulosa (case report)].

Computed tomography of lumbar spine in a case of pustulotic arthroosteitis demonstrates unusual proliferative changes of syndesmophytes and of the vertebral body. The osseous structures look "frayed out" and resemble the changes of sternoclavicular hyperostosis in early stages. A three dimensional picture shows that these proliferative changes apparently consist of irregular strips of bone. In addition, the vertebral body is surrounded by a soft tissue structure which probably indicates a perivertebral inflammatory process. Radiological changes of the lumbar spine in pustulotic arthroosteitis …

Effect of Single Versus Multiple Fractures on Systemic Bone Loss in Mice.

Systemic bone loss after initial fracture contributes to an increased risk of secondary fracture. Clinical research has revealed an associat … -body BMD was assessed at 4 days, 2 weeks, and 4 weeks after fracture. The microstructure of the L5 vertebral body and contralateral femur was assessed using micro-CT (μCT) and biomechanical tests (vertebral compression test and three-point bending test) at 2 and 4 weeks. Tartrate-resistant acid phosphatase (TRAP) staining, sequential fluorescence labeling, and …

A Study of Risk Factors for Early-Onset Adjacent Vertebral Fractures After Kyphoplasty.

Study designRetrospective study.ObjectivesTo elucidate risk factors for early-onset (2 months after initial kyphoplasty) adjacent vertebral fracture (EO-AVF) after kyphoplasty.MethodsA total of 108 vertebral bodies (95 patients) were included in this study. We examined patient backgrounds, the spinal level of EO-AVFs, surgery-related factors, and imaging findings. We divided the cases into 2 groups: patients with EO-AVF and patients without EO-AVF. Univariate, correlation, and multivariate analyses were conducted to reveal the risks factors for EO-AVFs for these 2 groups.ResultsEO-AVFs develop

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… A randomized trial of balloon kyphoplasty and nonsurgical management for treating acute vertebral compression fractures: vertebral body kyphosis correction and surgical parameters. Spine (Phila Pa 1976). 2013;38:971–983. doi:10.1097/BRS.0b013e31828e8e22 5. … The biomechanical effects of kyphoplasty on treated and adjacent nontreated vertebral bodies. J Spinal Disord Tech. 2005;18:84–91. 30. Pflugmacher R, Schroeder RJ, Klostermann CK. …

Spondylodiscitis - a silent infection with loud consequences.

The aim of this study is to present a case of a patient with spondylodiscitis. Spondylodiscitis is a infection of the spine involving the vertebral body and/or intervertebral disc, often caused by Staphylococcus aureus and Enterobacteriaceae. It most commonly affects the lumbar spine, begins in the vertebral body endplates and can lead to destruction of bone structures and involvement of the intervertebral disc and surrounding tissues. A 53-year-old man developed lumbar spine pain after an infection of unknown origin accompanied by fever and weakness. After two weeks, when the pain worsened an…

Adjacent vertebral fractures in the lumbar and thoracic spine after balloon kyphoplasty: A finite element analysis.

The purpose of the present study was to mechanically verify after vertebral augmentation (AVA) scores using a finite element method (FEM) with accurate material constants of balloon kyphoplasty (BKP) cement. Representative cases with AVA scores of 1 (case 1), 3 (case 2), and 5 (case 3) among patients with vertebral body fractures who underwent BKP were analyzed. A FEM model consisting of 5 vertebral bodies was created, including the injured vertebral body in each case. The amount of displacement for each load (up to 4000 N) between the upper and lower vertebral bodies of each model was measure…

Aspects of atypical degenerative lesions of vertebrae.

Over the last 20 years, several authors have reported aspects of degenerative disease of the vertebral column with irregularity and sclerosis of the margins of the vertebral bodies [2, 4, 7-9, 13, 15, 17]. Twenty cases of such atypical degenerative vertebral lesions have been studied over a two year period and their radiological characteristics have been compared with vertebral lesions of infective origin and in the rheumatoid disorders.

Unilateral posterior vertebral column resection for severe thoracolumbar kyphotic deformity caused by old compressive vertebrae fracture: a technical improvement.

Severe thoracolumbar kyphotic deformity caused by old compressive vertebrae fracture remains a big challenge for spine surgeons. When symptoms related to significant deformities cannot be adequately managed conservatively, posterior vertebral column resection (PVCR) is required, but with long operating time and severe blood loss. We develop a UPVCR technique, which is done through a unilateral approach instead of a bilateral approach, vertebral body resection advancing to cross the midline in an abrasive way from an extreme oblique orientation enable the resection of most contralateral vertebr…

Surgical treatment of solitary plasmocytoma of the spine: case series.

The mean survival of patients with skeletal solitary plasmocytoma is 75% at 5-year follow-up. This highly osteolytic tumor may compromise spinal stability. Radiotherapy is effective in local control of the disease, however, it is not effective in restoring spinal stability. Fracture risk and progressive vertebral collapse persist. For this reason, we must consider the need to establish the probability of progressive vertebral collapse, based on the degree of involvement of the vertebral body at the time of diagnosis. We used parameters described by Taneishi and Kaneda, as well as those of Hell…

Minimally Invasive Approach for Diffuse Idiopathic Skeletal Hyperostosis (DISH)-Related Vertebral Fractures: A Case Report on Combining Vertebral Cement Augmentation and Cement-Augmented Pedicle Screw Instrumentation.

Diffuse idiopathic skeletal hyperostosis (DISH)-related vertebral fractures often require surgical intervention due to associated spinal ins … tivities. Radiographic evaluation at the six-month postoperative stage confirmed the maintenance of vertebral body reduction with no indications of implant failure. In DISH-associated vertebral fractures, the combined application of vertebral cement augmentation and cement-augmented PS instrumentation offers a minimally invasive solution that expedites fracture …

[Vertebral actinomycosis with spinal cord compression. A case report].

INTRODUCTION: Vertebral involvement of actinomycosis is extremely rare and associated spinal cord compression is unusual. EXEGESIS: We report a case of a 31-year-old man with vertebral actinomycosis presenting with spinal cord compression. Magnetic resonance imaging demonstrated a paravertebral abscess and lytic areas on the vertebral body of C5 requiring emergency surgery and antibiotic treatment. The patient was still asymptomatic after 12 months of follow-up. CONCLUSION: Clinical aspects of this unusual localization are reviewed. Treatment may be particularly difficult.

Vertebra collapse due to primary amyloidosis causing neurological compromise.

In primary amyloidosis (AL), a fibrillar protein (amyloid light chain) is deposited in many organs; however, it is rare to have involvement of the vertebral bodies. Multiple myeloma is a well-known systemic amyloid disease that frequently has vertebral involvement. However, the pathology of vertebral involvement of these two clinical entities differs significantly. We report a patient with L4 vertebral collapse because of primary AL, causing neurological compromise that improved with surgical treatment. Deposition of amyloid and following demineralisation caused the vertebral collapse. Primary

How I do it: en-bloc thoracic vertebrectomy.

BACKGROUND: Some young patients with preserved functional status suffering from aggressive isolated neoplastic disease of the thoracic spine may be eligible from curative en-bloc vertebrectomy surgical treatment. METHOD: Long-segment posterior pedicle screw fixation is performed. Complete excision of the posterior arch and of ribs posterior aspect is performed. Finger blunt dissection is performed between vertebral body, pleura, and aorta allowing to place a soft abdominal valve and then Gigli saws surrounding the anterior aspect of the spine, in order to saw the upper and the lower discs. Un…

C3 Vertebral Metastases From Tongue Adenoid Cystic Carcinoma: A Rare Case Report.

We report a rare case involving a patient with C3 vertebral body metastasis secondary to adenoid cystic carcinoma of the tongue.Five years after local resection of the primary tumor, magnetic resonance imaging showed a metastasis located in the left posterior border of the C3 vertebral body. Additionally, multiple pulmonary metastases were identified by computed tomography. Based on these findings, the patient underwent C2-3, C3-4 discectomy; C3 corpectomy; and titanium mesh fusion with a Zephir plate. The diagnosis was confirmed by the pathology findings. During 6 months of follow-up, the pat…

Myelopathy due to scoliosis with vertebral hypertrophy in Klippel-Trenaunay-Weber syndrome.

We describe a 37-year-old man complaining of right back pain and gait disturbance. He had a big soft tumor on his right back, hemihypertrophy of the right lower extremity, and right thoracic scoliosis. We diagnosed Klippel-Trenaunay-Weber syndrome based on the pathological findings of the soft tumor. Computed tomography (CT) scan revealed severe spinal stenosis due to a hypertrophic vertebral body and facet joint at T7. Treatment by decompression of hypertrophic bone led to complete neurological recovery. To our knowledge, no case has been reported of Klippel-Trenaunay-Weber syndrome with myel…

Aggressive vertebral hemangiomas contain no adipose tissue resulting in thoracic spine kyphosis: A case report.

RATIONALE: Aggressive vertebral hemangiomas (AVHs) destroy continuous vertebral bodies and intervertebral discs and resulting in spinal kyphosis is extremely rare. The very aggressive behavior was attributable to its significant vascular component and contained no adipose tissue. PATIENT CONCERNS: We report a case of thoracic spine kyphosis of AVHs with multiple vertebral bodies and intervertebral disc destruction in a 45-year-old woman. DIAGNOSES: Based on the imaging studies, the patient underwent surgical removal of this lesion and spinal reconstruction. Histopathology consistent with ver

Study on the influence of balloon dilation mode on the intravertebral cleft of osteoporotic fracture.

BACKGROUND: Intravertebral cleft is common in osteoporotic vertebral compression fracture, and the bone sclerosis around the fissure brings difficulties to the surgical treatment. It is not known whether the balloon dilatation mode of percutaneous kyphoplasty affects the distribution of bone cement in the fracture vertebral body and further affects the surgical effect. The purpose of this study was to discuss the effect of balloon dilatation mode on percutaneous kyphoplasty in the treatment of osteoporotic vertebral fractures with intravertebral cleft. METHODS: According to the inclusion crit…

Bilateral percutaneous kyphoplasty achieves more satisfactory outcomes compared to unilateral percutaneous kyphoplasty in osteoporotic vertebral compression fractures: A comprehensive comparative study.

BACKGROUND: Osteoporotic vertebral compression fractures (OVCFs) are the most common complication of osteoporosis, a worldwide disease that … group. BPKP achieved significantly higher improvement in middle height and volume of the fractured vertebral body than UPKP did. There were significantly higher losses of anterior, middle height and volume of the fractured vertebral body in the UPKP group at 2-year follow-up than in the BPKP group. At the final follow-up, Oswestry Disability Index (ODI) of BPKP …

Postoperative Clinical Outcomes of Balloon Kyphoplasty Treatment: Would Adherence to Indications and Contraindications Prevent Complications?

STUDY DESIGN: We retrospectively assessed the postoperative clinical outcomes of balloon kyphoplasty (BKP). PURPOSE: To evaluate the risk factors for complications and to reconfirm the indications and contraindications for BKP. OVERVIEW OF LITERATURE: In Japan, BKP is indicated for cases of osteoporotic vertebral fractures when pain is not improved even after an adequate period of conservative treatment. Contraindications to BKP include pedicle fracture, fracture of a flat vertebra, or fracture of the posterior wall of the vertebral body diagnosed on computed tomography. METHODS: Seventy-fi…