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InterTan nail versus Proximal Femoral Nail Antirotation-Asia in the treatment of unstable trochanteric fractures.

The goal of this study was to compare the outcomes of unstable trochanteric fractures treated with the InterTan nail (Smith & Nephew, Memphis, Tennessee) and the Proximal Femoral Nail Antirotation (PFNA-II) (Synthes, Solothurn, Switzerland). A total of 132 consecutive patients with unstable trochanteric fractures of the femur were enrolled in the study. The only intervention was InterTan nail or PFNA-II fixation of the unstable trochanteric fractures. Follow-up occurred at 1, 3, 6, and 12 months postoperatively and yearly thereafter. Radiographs were obtained at each follow-up, and all implant

Substance dependence treatment interventions: why we continue to fail people who use drugs in Asia.

INTRODUCTION: Substance use disorders contribute to a large number of preventable deaths in Asia; a majority of the negative health consequences are associated with opioid use. User friendly and effective drug dependence treatment is limited. SCOPE: Factors mediating drug user treatment outcomes in Asia are explored, with a focus on opioid use. Individual, programmatic, and legal/political issues which reduce the impact of drug user treatment are noted. DISCUSSION: Criminalization of drug users, inadequate insurance, chronic underinvestment, and an overall lack of therapeutic options create …

Biological signatures of asymptomatic extra- and intracranial atherosclerosis: the Barcelona-AsIA (Asymptomatic Intracranial Atherosclerosis) study.

BACKGROUND AND PURPOSE: Intracranial atherosclerotic disease (ICAD) remains a challenge for stroke primary and secondary prevention. Molecular pathways involved in the development of ICAD from its asymptomatic stages are largely unknown. In our population-based study, we aimed to compare the risk factor and biomarker profiles associated with intracranial and extracranial asymptomatic cerebral atherosclerosis. METHODS: The Asymptomatic Intracranial Atherosclerosis (AsIA) study cohort includes a random sample population of 933 white subjects >50 years with a moderate to high vascular risk (base…

Epidemiological and clinico-mycological profile of fungal wound infection from largest burn centre in Asia.

The current study was conducted to know the incidence, predisposing factors, spectrum, clinical profile and antifungal susceptibility (AFS) of fungal wound infection (FWI) in burn patients. Of a total of 71 patients, 20 (28.2%) emerged with the diagnosis of FWI. Fungal pathogens in this study were Candida tropicalis (14%), Candida parapsilosis (5.6%), Aspergillus niger (2.8%) and one each of Candida albicans (1.4%), Candida glabrata (1.4%), Syncephalestrum (1.4%) and Fusarium solani (1.4%). All patients with mould infections expired before the mycological culture results could be conveyed to c

Активизация глобальной борьбы с забытыми тропическими заболеваниями путем принятия мер в Азиатско-Тихоокеанском регионе.

По мере расширения местных, национальных и международных усилий по контролю и искоренению забытых тропических заболеваний (НТР) растет признание того, что 11 стран Юго-Восточной Азии вместе с Китайской Народной Республикой (П.Р. Китай) является причиной значительного бремени глобальной нищеты и болезней. В самом деле, примерно одна треть кишечных рулетов в мире, бóльшая часть передаваемых с пищей триматодных инфекций, половина активных трахомных инфекций и значительное число случаев лимфатического филариатиса (ЛФ), шистосомоза и арбовирусных инфекций происходят в этом регионе. В странах Меконг

Совпадение в аннотации оригинала
As local, national and international control and elimination efforts for the neglected tropical diseases (NTDs) expand, there is increasing recognition that the 11 Southeast Asian countries together with the People's Republic of China (P.R. China) account for a significant burden of global poverty and disease. Indeed, approximately one-third of the world's i…

A new paradigm for international disease control: lessons learned from polio eradication in Southeast Asia.

OBJECTIVES: This study evaluated the impact of international coordination on polio eradication in Southeast Asia. METHODS: Active surveillance systems for acute flaccid paralysis were assessed. Analyses focused on surveillance proficiency and polio incidence. RESULTS: Ten countries coordinated activities. Importations occurred and were rapidly contained in China and Myanmar. Countries that have been free of indigenous polio transmission for at least 3 years include Sri Lanka, Indonesia, Myanmar, and Thailand. In the remaining endemic countries--India, Nepal, and Bangladesh--poliovirus transm…

RT-PCR, nucleotide, amino acid and phylogenetic analyses of enterovirus type 71 strains from Asia.

A specific and sensitive method based on RT-PCR was developed to detect enterovirus 71 (EV71) from patients with hand, foot and mouth disease, myocarditis, aseptic meningitis and acute flaccid paralysis. RT-PCR primers from conserved parts of the VP1 capsid gene were designed on the basis of good correlation with sequences of EV71 strains. These primers successfully amplified 44 strains of EV71 including 34 strains isolated from Singapore in 1997 and 1998, eight strains from Malaysia isolated in 1997 and 1998, one Japanese strain and the neurovirulent strain EV71/7423/MS/87. RT-PCR of 30 strai

PVO / NGO initiatives, Asia. Karmajibi Kallyan (KKS), Bangladesh and Save the Children Fund Australia (SCFA).

Karmajibi Kallyan (KKS) and Save the Children Fund Australia (SCFA) are implementing a program that integrates HIV/AIDS prevention and income generation activities aimed at the pre-adolescent girl servants of commercial sex workers in the Rajbari district of Bangladesh. The initial objectives of the program were to identify and establish alternative income generating activities for 150 girl servants; provide literacy education to these girls based on such topics as primary health care (HIV/AIDS prevention), credit, and small business management; and promote HIV/AIDS awareness in the wider comm

[Hemoglobin abnormalities and glucose 6 phosphate dehydrogenase deficiency (G6PD) in 101 refugees from southeast Asia].

Hematological studies were performed systematically in 101 refugees from South-Eastern Asia living in the Grenoble area at the present time. We found: --4 haemoglobin E homozygosity, --29 haemoglobin E heterozygosity, --2 beta-thalassemia heterozygosity, --4 alpha-thalassemia heterozygosity, --14 glucose 6 phosphate dehydrogenase deficiencies.

Melioidosis in Asia: Hidden burden, epidemiological distribution, vaccine and therapeutic prospects, and public health priorities.

Melioidosis is an under-recognized tropical infectious disease caused by Burkholderia pseudomallei, an environmental pathogen that persists mainly in soil and surface water across tropical and subtropical regions. In Asia, the burden of melioidosis remains poorly defined because many cases are underdiagnosed, underreported, or clinically misclassified as tuberculosis, pneumonia, sepsis, or other bacterial infections. This narrative review examines the epidemiological distribution, transmission pathways, risk factors, vaccine and therapeutic developments, public health challenges, and future co…

Decolonizing addiction treatment in Eastern Europe and Central Asia: Confronting Russian narcology and Western retreat.

Eastern Europe and Central Asia (EECA) face a dual crisis in addiction treatment. On one side, Russian imperial legacies persist through punitive "narcology," now weaponized amid ongoing aggression. On the other, Western retrenchment, marked by abrupt aid suspensions and dwindling harm-reduction budgets, has weakened the evidence-based counterweight that once challenged authoritarian approaches. The result is a convergence of punitive logics that marginalizes people who use drugs, whether through active repression, such as the closure of methadone programs in Crimea, or sudden neglect, such as…

External Quality Assessment for Low Molecular Weight Heparin Monitoring in the Australasia/Asia-Pacific Region.

Low molecular weight heparin (LMWH) remains a widely utilized parenteral anticoagulant in hospital and outpatient settings for thromboprophy … from the past 6 years (2020-2025 inclusive) using RCPAQAP (Royal College of Pathologists of Australasia Quality Assurance Program) data, an international program with approximately 150 laboratory enrolments. Four samples are assessed annually at varied LMWH concentrations (0, 0.2-0.3, 0.5-0.6, 0.8-1.0 U/mL). Good reproducibility was demonstrated for d …

Special care dentistry undergraduate curriculum in Asia-Pacific: a descriptive study of 31 dental schools.

BACKGROUND: Special care dentistry (SCD) addresses the oral health needs of individuals whose disabilities, medical complexities, or social circumstances limit access to dental care. With rapid population ageing and a high disability prevalence, the Asia-Pacific region faces a growing demand for dentists competent in managing patients requiring special care. For the majority of patients requiring special care, routine basic dental care is helmed by the general dentist. While the International Association for Disability and Oral Health (iADH) has published undergraduate curriculum guidance for …

Treatment of Mantle Cell Lymphoma in Asia: Updated Consensus from the Asian Lymphoma Study Group.

PURPOSE: This paper reports up-to-date expert consensus from the Asian Lymphoma Study Group (ALSG) on treatment recommendations for mantle cell lymphoma (MCL) in Asia. MATERIALS AND METHODS: A closed session meeting of the ALSG was convened in August 2025 to discuss MCL management practices in Asia. Consensus recommendations from that meeting are summarized here, and take into consideration international guidelines, the current treatment landscape in Asia, and global and Asia-specific literature. RESULTS: In Asia, effective MCL management is limited by difficulties in accessing Bruton's tyro…

Temporal trends in mortality and disability from occupational asbestos exposure in Southeast Asia, 1990-2023.

OBJECTIVE: Occupational asbestos exposure remains a major public health concern in Southeast Asia (SEA), where use persists and comprehensive assessments are limited. METHODS: GBD 2023 data were used to estimate deaths and DALYs attributable to occupational asbestos exposure in SEA and 13 countries. Trends were analyzed by EAPC and Joinpoint, stratified by sex, age, and cause. RESULTS: Deaths increased markedly from 1990 to 2023, with rising ASMR. Males had substantially higher rates than females. Trends showed periods of increase, with continuous rises among females. Most countries showed i…

Visceral leishmaniasis elimination in South Asia: lessons learnt can inform disease elimination in East Africa.

In 2005, the governments of Bangladesh, India and Nepal, in partnership with the WHO, started the Kala-azar Elimination Programme (KEP) to reduce the incidence of visceral leishmaniasis to below 1 new case in 10 000 population. The target was achieved by Bangladesh in 2017 and validated in 2023. The KEP has demonstrated that, through a concerted approach and public-private partnership, it is possible to eliminate visceral leishmaniasis from the world's highest endemic region, Southeast Asia. The experience learnt can be used elsewhere for visceral leishmaniasis as well as for other diseases ta…