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The comorbidity of Axis I disorders in depressed pregnant women.

Depression during pregnancy is highly prevalent and is associated with increased risk of a variety of negative psychological and medical out … ) receiving care at a university hospital clinic and Maternal Mental Health Care centers in eastern Iowa and who screened positive for depression on the Beck Depression Inventory completed the Structured Clinical Interview for DSM-IV to assess comorbid mental health symptoms and diagnoses. Overall, findings demonstrate high rates of anxiety disorders a …

Evaluation of the Vulvar Cancer Histology Code Reported by Central Cancer Registries: Importance in Epidemiology.

CONTEXT: -Knowing the subtype of vulvar cancer histology is important for estimating human papillomavirus-related cancer etiology. Surveillance of human papillomavirus-related vulvar cancers informs public health decisions related to vaccination against human papillomavirus. OBJECTIVE: -To assess the accuracy of registry classifications of vulvar cancer and determine the histologic classification of cases reported as not otherwise specified. DESIGN: -Pathology specimens were collected from Florida, Iowa, and Hawaii cancer registries. Registry diagnosis was compared with the pathology report …

All-terrain vehicle safety knowledge, riding behaviors and crash experience of Farm Progress Show attendees.

INTRODUCTION: Although all-terrain vehicles (ATVs) are very popular in rural areas for both recreation and work purposes, the epidemiology of agricultural ATV use remains largely unknown. METHODS: Farm Progress Show attendees in 2012 (Boone, Iowa) and 2013 (Decatur, Illinois) were surveyed about ATVs, including riding behaviors, crash history, and safety knowledge. Descriptive and comparative analyses were performed (N=635 surveys). RESULTS: Over half of those surveyed lived on a farm and more than 90% had ridden on an ATV. Sixty-one percent rode at least once a week and 39% reported riding …

Protein concentration and mitochondrial content in the gastrocnemius predicts mortality rates in patients with peripheral arterial disease.

OBJECTIVE: This study evaluated the hypothesis that protein concentration and mitochondrial content in gastrocnemius biopsies from patients with peripheral arterial disease (PAD) predict mortality rates. BACKGROUND: PAD patients experience advancing myopathy characterized by mitochondrial dysfunction, myofiber degradation, and fibrosis in their ischemic legs, along with increased mortality rates. METHODS: Samples from the gastrocnemius of PAD patients were used for all analyses. Protein concentration was normalized to muscle wet weight, and citrate synthase activity (standard measure of mito

Effect of Single-Use Negative Pressure Wound Therapy on Postcesarean Infections and Wound Complications for High-Risk Patients.

OBJECTIVE: To evaluate the effect of a single-use negative pressure wound therapy (NPWT) system on postoperative complications after cesarean delivery. STUDY DESIGN: A historical control cohort of women was collected as part of a quality improvement project over a 6-month period. All women with at least 1 risk factor for postoperative complications were included in this control cohort. An intervention cohort of 110 women with at least 1 risk factor for postoperative complications was eligible to have a single-use NPWT system placed at the time of cesarean delivery. Primary outcomes were wound

A school-based study of adolescent all-terrain vehicle exposure, safety behaviors, and crash experience.

PURPOSE: More youth are killed every year in the United States in all-terrain vehicle (ATV) crashes than on bicycles, and since 2001, one-fifth of all ATV fatalities have involved victims aged 15 years or younger. Effectively preventing pediatric ATV-related deaths and injuries requires knowledge about youth riding practices. Our objective was to examine ATV use, crash prevalence, and riding behaviors among adolescent students in a rural state. METHODS: We administered a cross-sectional survey to 4,684 youths aged 11 to 16 years at 30 schools across Iowa from November 2010 to April 2013. Desc…

Evaluation of CAND2 and WNT7a as candidate genes for congenital idiopathic clubfoot.

Congenital idiopathic clubfoot is a common pediatric musculoskeletal deformity with no known etiology. The deformity reportedly follows a Mendelian pattern of inheritance. Recent work has demonstrated linkage in chromosome 3 and 13 in a large, multigeneration, highly penetrant family with idiopathic clubfoot. From the linkage region on chromosome 3, we selected the candidate genes CAND2 and WNT7a, which are involved in lower extremity development, and hypothesized mutations in these genes would be associated with the phenotype of congenital idiopathic clubfoot. The CAND2 gene was sequenced in

Management of the orbital floor in silent sinus syndrome.

BACKGROUND: Enophthalmos in a patient with an opacified hypoplastic maxillary sinus, without sinus symptomatology, describes the silent sinus syndrome. A current trend is to perform endoscopic maxillary antrostomy and orbital floor reconstruction as a single-staged operation. A two-staged approach is performed at our institution to avoid placement of an orbital floor implant in the midst of potential infection and allow for the possibility that enophthalmos and global ptosis may resolve with endoscopic antrostomy alone, obviating the need for orbital floor reconstruction. METHODS: A retrospec

Examination of the effect of nongenetic risk factors on the familial risk of breast cancer among relatives of postmenopausal breast cancer patients.

Relatives of postmenopausal breast cancer patients have a greater risk of breast cancer than do women with no family history of the disease. However, no study has previously examined the contribution of other breast cancer risk factors to risk in these relatives, thus precluding the ability to discern between shared environment or genes as the cause of familial aggregation. We conducted a nested case-control study of 251 index case families and 234 index control families. Incident breast cancer cases occurring in 1988-1989 and cancer-free controls were selected from a prospective cohort study.

Alzheimer's disease and related dementias state policies and mortality in the United States: A descriptive study.

BackgroundAlzheimer's disease and related dementias (ADRD) were the sixth leading cause of death among people aged 65 + in 2022 and are curr … 020. ADRD mortality steadily rose during 1999-2022. The first states to implement ADRD in 2008 were Iowa and Kentucky. The largest number of states added policies in 2013. South Dakota, Wyoming, Ohio, and Kansas were the last states to implement policies.ConclusionsOur study documented that all the states in the United States implemented a policy to re …

Evaluating soybean planting date and at-planting insecticide as a management strategy for Resseliella maxima (Diptera: Cecidomyiidae).

Soybean gall midge (Resseliella maxima Gagné) was confirmed in 2019 as a new species in the Midwestern United States. It is known to occur in seven states (Iowa, Kansas, Minnesota, Missouri, Nebraska, North Dakota, and South Dakota) and can cause up to 100% yield loss in soybean (Glycine max (L.) Merr.) for the first 30 m from the field edge. Field and greenhouse observations indicate R. maxima infests soybean stems through fissures at the base of the plant during early vegetative growth stages. Given the importance of plant stage for infestation and the limited knowledge on chemical control, …

Increasing prevalence of Ovavesicula popilliae (Microsporidia), a pathogen of Japanese beetle (Coleoptera: Scarabaeidae), in the Midwest and Northcentral United States from 1999 to 2025.

Distribution of Ovavesicula popilliae Andreadis & Hanula (Microsporidia) in the United States was updated by sampling 232 new sites, with a … ted airports and parks. The pattern of O. popilliae establishment in Minnesota, Michigan, Colorado, Iowa, and Wisconsin were similar: O. popilliae was first found in densely populated or frequently visited areas, dispersing from there to some but not all sites within 20 k over the next 10 to 20 yrs. Dispersal of O. popilliae beyond 20 k was sporadic, a …

Documentation of high blood pressure measurements in the emergency department: factors associated with discussion and comparison to other settings.

Asymptomatic hypertension is common among emergency department (ED) patients. However, follow-up occurs infrequently. Because recognition of elevated readings is a prerequisite for referrals, we investigated the factors associated with the documentation of elevated BP measurements in provider notes. Electronic medical record (EMR) data from the University of Iowa Healthcare system were used to identify patients who had an outpatient ED, primary care, or urgent care visit with high BP (140/90 mmHg or greater) from 01 January 2017 through 31 December 2021 and no prior hypertension diagnosis. We …

Oral fluids for detection and characterization of Salmonella in commercial finisher pigs.

Salmonella remains an important pathogen in swine production due to its impact on animal health and its role in foodborne illnesses. However, routine surveillance in pigs relies largely on fecal sampling, which can be labor-intensive and difficult to scale across large production systems. This study aimed to develop and evaluate a novel approach for monitoring Salmonella in finisher pigs using oral fluids in combination with sequential enrichment, culture, and polymerase chain reaction (PCR). A cross-sectional study was conducted at three commercial finisher sites in Iowa between February and …

Tongue myofunctional performance, strength and functionality index in Class II and Class III dentofacial deformities.

BACKGROUND: Individuals with dentofacial deformities (DFD) present several orofacial myofunctional alterations. However, the characteristics … nts were evaluated using the Orofacial Myofunctional Evaluation with Scores (OMES) protocol and the Iowa Oral Performance Instrument (IOPI) for tongue strength measurements. The tongue functionality index was obtained by summing the z-scores of the total tongue score and saliva-swallowing strength. RESULTS: Patients with DFD showed lower total OMES sc …

[Outcomes of music perception assessment and appreciation questionnaire in postlingually-deafened cochlear implant users with Chinese cultural background].

Objective: To evaluate the music perception ability and appraisal status of cochlear implant adult users, then to compare those with normal-hearing subjects. Methods: The Iowa Musical Background and Appreciation Questionnaire (IMBAQ) was conducted to evaluate 20 cases of post-lingual deafness cochlear implant recipients (9 males, 11 females) aged 12-61(mean=28.8 yrs). Those music perception abilities were tested via Music Perceptional Evaluation Platform. Two kinds of tone(C#3, C#5)were carried out in the music perception test, including the Just Noticeable Difference (JND) Test, the Pitch-Dir…

Insights Into History and Trends of Teaching and Learning in Stomatology Education: Bibliometric Analysis.

BACKGROUND: Stomatology education has experienced substantial transformations over recent decades. Nevertheless, a comprehensive summary enc … dom emerged as the leading contributors to research. Among academic institutions, the University of Iowa produced the highest number of publications. The Journal of Dental Education was identified as the journal with the highest citation. Wanchek T authored the most highly cited articles in the field. Emerging research hotspots were characterized by ke …

Caloric restriction worsens decision-making impairments and gut dysbiosis after brain injury in male rats.

Traumatic brain injury (TBI) causes long-term deficits in decision-making and disrupts the gut microbiome. Dysbiosis of the gut microbiome i … tal controlled cortical impact TBI. Rats were trained on the rodent gambling task, an analog of the Iowa gambling task, to assess risk-based decision-making. The microbiome was sampled through the acute to subacute period post-injury and lesion size and microglia counts evaluated at 10 weeks post-injury. Caloric restriction did not affect decision-maki …

Application of Orofacial Muscle Strength Measurement to Screen for Penetration/Aspiration Risk in Older Adults With Sarcopenia: A Diagnostic Accuracy Study.

BACKGROUND: Early identification of penetration/aspiration (P/A) risk in older adults with sarcopenia is crucial to prevent complications an … gether, 54 participants underwent orofacial muscle strength measurements (the index test) using the Iowa Oral Performance Instrument and a videofluoroscopic swallowing study (VFSS) (the reference test) to evaluate for the presence of P/A. Receiver operating characteristic (ROC) curve analysis was performed to determine orofacial muscle strength based o …

В 3xTg-AD, но не в Tg-SwDI Mice.

В настоящее время широко признается, что развитие нейродегенеративных заболеваний зависит и влияет на многие патологические процессы как в мозге, так и на периферии. Инфламационное, сердечно-сосудистое, метаболическое, цереброваскулярное, аутоиммунное и другие факторы окружающей среды были тщательно изучены и продемонстрированы, в частности, в связи с началом, патогенезом и клиническим исходом болезни Альцгеймера (AD), болезни Паркинсона (PD), церебральной амилоидной ангиопатии (CAA), множественным склерозом и другими неврологическими расстройствами. Аналогичным образом, были документально заф

Совпадение в аннотации оригинала
It is now widely accepted that the development of neurodegenerative diseases depends on and affects many pathological processes, both in the … P, tau, and Psen1), and Tg-SwDI mice, expressing human APP with the Swedish and vasculotropic Dutch/Iowa mutations in the brain. We documented splenomegaly, immunoglobulin-associated spleen amyloidosis, and an increase in the percentage of neutrophils in the spleen and macrophages in the liver in 3xTg-AD mice but not in age-matched Tg-SwDI mice, which …