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Optical Coherence Tomography and Optical Coherence Tomography Angiography in Neglected Diseases.

A group of self-limiting and frequently neglected diseases exist in the literature like Rickettsial disease, Malaria, Dengue fever, Chikungunya, West Nile virus infection, Rift Valley fever, Bartonellosis, or Lyme disease which are poorly understood due to lack of proper diagnostic testing. Currently, multimodal imaging has become a critical modality in the diagnosis and management of ocular diseases. Optical coherence tomography (OCT) is one such remarkable imaging modality in the field of ophthalmology providing high-resolution, cross-sectional images of the retina and choroid with the recen…

Global change: impact, management, risk approach and health measures--the case of Europe.

Global changes, including an increase in trade and global warming, which act on the environment, are likely to impact on the evolution of pa … ch of these diseases. As a result of this process, six priority diseases were selected: bluetongue, Rift Valley fever, West Nile fever, visceral leishmaniasis, leptospirosis and African horse sickness. The main recommendations were: to develop epidemiological surveillance, to increase knowledge of epidemiological cycles, to develop research into these diseases and …

Mosquitoes of the genus Culex in the Suez Canal Governorates.

Mosquitoes are among the most annoying and important vectors of human and animal diseases as malaria, filariasis, yellow fever, rift valley fever...etc. In this paper, it was aimed to study the present status of species of genus Culex in the Suez Canal Governorates after the reconstruction and developmental projects. Five species of Culex were identified: C. pipiens, C. univittatus, C. antennatus, C. poicilipes and C. pusillus. The latter species was represented by two specimens. C. pipiens was the commonest species both indoors and outdoors. C. antennatus and C. poicilipes were found only out…

Inhibition of Crimean-Congo hemorrhagic fever viral infectivity yields in vitro by ribavirin.

Ribavirin was evaluated as a potential therapeutic for Crimean-Congo hemorrhagic fever (CCHF). Viral yields for strains of CCHF virus from E … rin at least 9 times greater was required to induce a comparable inhibitory effect on the yields of Rift Valley fever virus, for which the drug has been shown to inhibit replication in monkeys and rodents.

Attenuated viral strains of priority pathogens for potential use in controlled human infection model studies: A scoping review.

BACKGROUND: There are several known pathogens and families identified as high risk for pandemic potential. It is essential to study these pa … mic Preparedness Innovations (CEPI) identified priority pathogens (Ebola, Lassa virus, Nipah virus, Rift Valley fever virus, chikungunya virus and Middle East respiratory syndrome-related coronavirus) that have been administered to humans. DESIGN: A comprehensive literature search of multiple databases was performed by an information specialist. All search results …

Sensitivity Analysis in an Immuno-Epidemiological Vector-Host Model.

Sensitivity Analysis (SA) is a useful tool to measure the impact of changes in model parameters on the infection dynamics, particularly to q … the epidemic or the infectiousness at different phases of an outbreak. As a case study, we consider Rift Valley Fever Disease utilizing parameter estimations from prior studies. SA indicates that [Formula: see text] increase in within-host pathogen growth rate can lead up to [Formula: see text] increase in [Formula: see text] up to [Formula: see text] increase in s …

Изменение климата и растущая угроза буньявирусов.

Антропогенное изменение климата и его последствия для инфекционных заболеваний занимают центральное место в научных дискуссиях и дискуссиях по вопросам здравоохранения на протяжении более трех десятилетий. В 2026 году мы вступили в фазу адаптации к изменению климата, при этом накапливаются данные, свидетельствующие о том, что текущая изменчивость климата непосредственно изменяет динамику множественных трансмиссивных вирусов, включая буньявирусы. Буниавирусы представляют собой разнообразную группу сегментированных, негативных вирусов РНК, которые включают в себя значительные человеческие и вете

Совпадение в аннотации оригинала
Anthropogenic climate change and its implications for infectious diseases have been central to the scientific and public health discourse fo … mented, negative-sense RNA viruses that include significant human and veterinary pathogens, such as Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus, Oropouche virus, and Cache Valley fever virus. Despite their medical and veterinary importance, climate-virus relationships remain comparatively less well characterized for bunyaviruses than for viruses …

Emerging phleboviruses.

The Bunyavidae family is the largest grouping of RNA viruses and arguably the most diverse. Bunyaviruses have a truly global distribution an … in 2011, causing foetal malformations in ruminants. In addition, some well-known bunyaviruses like Rift Valley fever and Crimean-Congo haemorrhagic fever viruses continue to emerge in new geographical locations. In this short review we focus on newly identified viruses associated with severe haemorrhagic disease in humans in China and the US.

[Prevention of zoonoses: creation of a unit for early detection of animal infections].

In a context in which known and potential zoonoses are emerging (simian retrovirus infections, SRAS, West Nile, H5N1 avian influenza, etc.), French army veterinarians have been tasked with assessing epidemiological risks related to animals in proximity with troops, particularly during foreign operations. They have already completed surveys of more than 70 infections (toxoplasmosis, leishmaniasis, rickettiosis, leptospirosis, Q fever, hepatitis E, Rift valley fever, etc.). The strategy consists of detecting pathogenic agents ("the right sample, at the right time, and kept in the right condition…

Distribution, host preference and infection rates of malaria vectors in Mauritania.

This study reports for the first time on the distribution, host preference and infection rates of malaria vectors in Mauritania. It was conducted during an outbreak of Rift valley fever. Three anopheline species were reported. An. arabiensis was the predominant species observed in all regions whereas An. pharoensis and An. funestus were observed along the south border in the Senegal River valley where extensive irrigation schemes are present. The distribution limits of anopheline species were observed from the Senegal River basin in the Trarza region up to the south limit of the Saharan desert…

Rapid development of vaccines against emerging pathogens: The replication-deficient simian adenovirus platform technology.

Despite the fact that there had been multiple small outbreaks of Ebola Virus Disease, when a large outbreak occurred in 2014 there were no v … ibes progress in human and livestock vaccine development for three outbreak pathogens, Ebola virus, Rift Valley Fever Virus and Middle East Respiratory Syndrome Coronavirus.

[Viral hemorrhagic fevers: what is the risk for travelers?].

The term hemorrhagic fever covers a number of diseases with different clinical and epidemiologic features. All these diseases are zoonoses but their occurrence is not confined to tropical areas. Some occur in polar zones. Travelers to endemic areas for these diseases are at risk of infection. There are two modes of transmission. Arthropods are vectors for some diseases such as yellow fever, dengue fever, and Rift Valley fever which are carried by mosquitos and Congo-Crimea virus which is carried by ticks. Airborne contamination by rodent excrement is responsible for transmission of hantaviruse…

Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.

A series of 23 Amaryllidaceae isoquinoline alkaloids and related synthetic analogues were isolated or synthesized and subsequently evaluated in cell culture against the RNA-containing flaviviruses (Japanese encephalitis, yellow fever, and dengue viruses), bunyaviruses (Punta Toro, sandfly fever, and Rift Valley fever viruses), alphavirus (Venezuelan equine encephalomyelitis virus), lentivirus (human immunodeficiency virus-type 1) and the DNA-containing vaccinia virus. Narciclasine [1], lycoricidine [2], pancratistatin [4], 7-deoxypancratistatin [5], and acetates 6-8, isonarciclasine [13a], cis…

Enhanced mosquito blood-finding success on parasitemic hosts: evidence for vector-parasite mutualism.

The generalized hematopathology frequently found in animals infected with vector-borne pathogens may maximize transmission by enhancing the ability of vectors to locate blood in infected hosts. We tested this idea of mutualism between parasite and vector by comparing duration of probing of mosquitoes feeding on noninfected and on malaria-(Plasmodium chabaudi) or arbovirus-(Rift Valley fever virus) infected animals. We found that median duration of probing (blood location) on infected rodents was reduced by at least 1 min as compared to noninfected rodents. This enhanced ability of vectors to l…

Detection and genetic diversity of Wolbachia and its associated prophage WO in mosquito populations from Ethiopia.

Arboviral diseases transmitted by mosquitoes, including dengue, Chikungunya, Zika, yellow fever, West Nile virus (WNV), and Rift Valley fever (RVF), pose a significant public health challenge globally, particularly impacting populations in low and middle-income countries. Conventional mosquito control methods, which primarily rely on insecticides, face critical challenges, including the development of insecticide resistance and environmental concerns. In this context, Wolbachia, an endosymbiotic bacterium, presents an alternative strategy due to its ability to manipulate mosquito reproduction …

Methodological aspects of serosurveillance in resource-poor settings.

Animal production is important for the agricultural economy in low-income countries, but is threatened by infectious diseases. Serosurveys are conducted for different reasons such as disease detection, risk factor studies, disease monitoring and establishing disease-free status. Most reports on such serosurveys include some discussion about methodological constraints but still, by necessity, rely on serological results for case definition. This study uses a cross-sectional serosurvey for foot-and-mouth disease (FMD), Rift Valley fever (RVF) and contagious bovine pleuropneumonia (CBPP) in cattl…

Mosquitoes (Diptera: Culicidae) in Mauritania: a review of their biodiversity, distribution and medical importance.

Although mosquitoes (Diptera: Culicidae) are important disease vectors, information on their biodiversity in Mauritania is scarce and very d … in the Senegal River basin. Culex poicilipes and Cx. antenattus were naturally found infected with Rift valley fever virus in central and northern Mauritania following the Rift valley outbreaks of 1998 and 2012. Recently, Ae. aegypti emerged in Nouakchott and is probably responsible for dengue fever episodes of 2015. This paper provides a concise and up-to-date ov …

Cross-Sectional Analysis of Serologic Response to Arthropod-Borne and Hemorrhagic Fever Viruses in Ghanaian Livestock Herders.

Zoonotic diseases account for more than 60% of emerging infectious diseases, and they are the leading cause of pandemics. As humans and live … dults at five military and three civilian sites across Ghana. The observed seroprevalence rates for Rift Valley fever virus (RVFV), Crimean-Congo hemorrhagic fever virus (CCHFV), Ebola virus, Lassa virus, and Marburg virus were 14.7%, 7.0%, 2.3%, 1%, and 0%, respectively. Microneutralization data further verified virus-specific neutralization positives of the total …

A comparison of indirect immunofluorescence and electron microscopy for the diagnosis of some haemorrhagic viruses in cell cultures.

Yellow fever, dengue (types 1, 2 and 4), Chikungunya, Rift Valley fever, Ebola, Marburg, and Lassa viruses were inoculated into susceptible cell cultures and daily investigated by indirect immunofluorescence (IFA) and electron microscopy (EM) with a view to achieve an early detection-identification of these agents. Compared to the other cell lines tested (Vero, BHK-21 and Aedes albopictus), CV-1 cells were found to be more sensitive. Viral antigens were detected by IFA from a few hours post inoculation (CHIK and RVF) to a maximum of 3 days (YF and EBO). For most of the viruses studied, the cyt…