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[Preparation and biomechanics study of biological artificial knee joint prosthesis with stereo mesh surface in rabbit].

OBJECTIVE: To develop a kind of biological artificial knee joint prosthesis with stereo mesh surface for rabbit, to observe its function aft … as self-designed. The adjacent 4/5 surface of femur and tibia stem of the prosthesis was covered by stainless steel stereo mesh, the inner surface of femur condyles and tibia plateau was welded with two layers of stainless steel stereo mesh, then the prosthesis underwent biological fixation in the experimental group. Meanwhile, prosthesis having smooth marrow int …

[Survival of dual mobility socket with a mean 17 years follow-up].

PURPOSE OF THE STUDY: Within the framework of the 2007 symposium of the French Hip and Knee Society devoted to the dual mobility socket, we report a retrospective multicentric series of 438 first-intention total hip prostheses with a dual mobile socket at 17 years mean follow-up. The purpose of our report was to ascertain the 15-year survival and analyze failures. MATERIAL AND METHODS: The series included 438 first-intention prostheses. This was a homogeneous multicentric series. Sockets were: 80 Novae-1 titanium Serf cups and 358 Novae-1 stainless steel Serf cups. All stems were inserted wit…

Cyclic fatigue resistance of two NiTi rotary instruments after blue heat treatment.

BACKGROUND: This study evaluated the cyclic fatigue resistance of two blue heat-treated rotary instruments. Thirty files (15 Eflex Blue and 15 BlueShaper) activated by an E-CONNECT motor at 350 RPM with a 2.5 N torque were evaluated. MATERIAL AND METHODS: A stainless-steel device with three different curvatures (25°, 45°, and 90°) was fixed to a SHIMADZU tensile testing machine to measure cyclic fatigue. The instruments were placed on the motor at a constant speed, then on the testing device; the time to each instrument's fracture was recorded. Tension, time, and instrument deformation were m

Food allergen immunotherapy via electrospray coated microneedles - a potential transdermal therapy.

Microneedle (MN) technologies offer a minimally invasive platform for allergen delivery; however, controlled transdermal administration of complex allergenic proteins remains a challenge. This communication reports the fabrication and evaluation of peanut (PN), and pistachio (PS) loaded polylactic-co-glycolic acid (PLGA) coatings onto stainless-steel MNs via electrohydrodynamic atomisation (EHDA). Electrosprayed coatings exhibited uniform morphology and comparable hydrophilicity across formulations. In-vitro release study revealed an early burst (20% release within 24 h) followed by sustained

Mechanistic Insights into the Electrochemical Calcium-Tin Alloying Reaction.

Alloy-type anodes have shown excellent electrochemical performance in various ion-battery systems, such as lithium and sodium, owing to thei … driven alloying behavior of calcium with tin using bulk Sn foils and nanostructured Sn coatings on stainless steel in half-cell configuration to evaluate intrinsic reactivity, transport properties, and kinetic limitations. Electrochemical techniques were combined with XPS, ToF-SIMS, and a simulation-based model to characterize phase formation and reaction dynami …

Non-proximate, Hand-Held Probe with Positional Feedback for Real-Time Analysis of Three-Dimensional Object Surfaces.

A variety of non-proximate mass spectrometry techniques have been implemented to sample organic analytes from distant surfaces, but they frequently risk signal carryover and loss by relying on unheated plastic tubing to transfer analytes back to the instrumentation. Non-proximate desorption photoionization (NPDPI) has used heated and passivated stainless steel transfer tubing since its inception, allowing clean but painstaking analysis of large objects. A unique new design based on gooseneck tubing confers flexibility comparable to that of plastic but resists organic molecule loss to the trans…

Effect of Y2O3 Content on the Microstructure and Thermal Shock Resistance of Al2O3-Y2O3 Composite Coatings.

Thermal shock resistance is a critical parameter for evaluating the long-term service reliability of protective coatings in high-temperature molten-salt environments. In this study, Al2O3-Y2O3 composite coatings containing 0, 2, 5, and 8 wt.% Y2O3 were fabricated on 316L stainless-steel substrates by atmospheric plasma spraying (APS). Their phase constitution, microstructure, mechanical properties, and thermal shock resistance were systematically investigated. The results showed that, with increasing Y2O3 content, the relative content of α-Al2O3 gradually increased, whereas the coating densifi

Revisiting the Carbon Footprint of Single-Use Technologies in Biomanufacturing: A Bottom-Up Analysis Reveals a Paradigm Shift.

The biopharmaceutical industry increasingly relies on single-use technologies (SUT) for operational flexibility. For a long time, SUT was considered more sustainable than stainless-steel (SST) systems due to water and energy savings. This study re-evaluates this paradigm via a detailed bottom-up analysis of the SUT carbon footprint at the 2000 L scale. Our analysis, based on two real-world facility case studies (a full-SUT and a hybrid-SUT model), shows that the CO2 footprint of SUT is significantly higher than previously assumed. This granular analysis, based on physical disassembly and updat

Template guided versus freehand rod bending in spinal deformity surgery: a feasibility study.

Spinal deformity correction relies on osteotomies and precisely contoured rods, which are critical for restoring sagittal alignment. Inaccurate rod bending may compromise alignment and increase the risk of junctional failure. This feasibility study compares the accuracy of template-guided versus freehand rod contouring in a simulated environment. Using SurgiMap® software, 12 double-curved rods were designed from full-spine radiographs. Six surgeons from a tertiary spine centre bent rods freehand or using 2D paper templates. Two rod specifications were tested: ⌀4.0 mm stainless steel rods for c…

Antibacterial efficacy of recombinant phage lysin JD007-LY01 against Staphylococcus aureus in food matrices.

Bacteriophage endolysins can specifically bind to and efficiently lyse host bacteria, and therefore considered promising alternatives to ant … esistant S. aureus (MRSA) counts. It also reduced biofilm-associated cell counts on polystyrene and stainless steel surfaces. Collectively, these results indicate that JD007-LY01 exhibits improved lytic activity and a broader spectrum compared with LY01, supporting the feasibility of domain recombination as a strategy to enhance certain antibacterial properties o …

Multidisciplinary Oral Rehabilitation in Osteogenesis Imperfecta: 18-Year-Old Case Report.

Osteogenesis imperfecta (OI) is a hereditary connective tissue disorder characterized by bone fragility and Type I collagen defects. Althoug … neral anesthesia. Management included vital pulp therapy to promote apexogenesis in immature teeth, stainless steel crowns for posterior rehabilitation, and composite restorations using universal adhesive systems containing 10-MDP. A conservative, non-extraction strategy was adopted to minimize mandibular fracture risk. This case highlights that dental pathology …

Distinct patterns of prion strain deposition and toxicity in a novel whole brain organotypic slice culture system.

Prion diseases are fatal transmissible neurodegenerative diseases that affect many mammals, including humans, caused by the templated misfolding of the prion protein. Different conformations of misfolded prions can occur, leading to distinct disease phenotypes or strains and the accumulation of prions in distinct brain regions. How prion structure influences this brain tropism is not clear, but the transmissible nature of prion diseases has allowed for the development of ex vivo brain slice models of disease. To date, work has been done in cerebellar cultures, but prion diseases are known to d

Delayed Tibial Osteomyelitis 37 Years After Habu Snake Envenomation: Limb Salvage With Local Antibiotic Perfusion and Areolar Tissue Grafting.

Chronic osteomyelitis in elderly patients traditionally necessitates extensive surgical interventions associated with high morbidity. We report successful minimally invasive limb salvage in an 84-year-old man with chronic tibial osteomyelitis, employing continuous local antibiotic perfusion (CLAP) and perifascial areolar tissue (PAT) grafting. The patient presented with a one-year history of purulent drainage from the anterior tibial crest, occurring 37 years after a habu snake (Protobothrops flavoviridis) bite at the same site. MRI revealed characteristic bone marrow edema, and microbiologica

A semiconductor SERS sensor of corrosion-resistant PPy/GO composite film by electrochemical growth for detecting crystal violet residues in fresh fish tissue.

Crystal violet (CV) residues in Marine food have produced a severe health threat in human life. In this study, we proposed a semiconductor surface-enhanced Raman scattering (SERS) sensor of corrosion-resistant Polyaniline/Graphene oxide (PPy/GO) film by electrochemical growth method to detect CV residues in fresh fish tissue. A PPy/GO dispersion solution was one-step deposited on a stainless steel sheet surface by electrochemical polymerization process to form a PPy/GO composite film acting as a semiconductor SERS substrate. Since the substrate of PPy/GO film was mainly composed of GO sheet wi…

Influence of the Brushing Motions on the Dynamic Cyclic Fatigue Resistance of the Reciproc Blue Instrument: In vitro Study.

INTRODUCTION: This study aimed to evaluate the dynamic cyclic fatigue resistance of Reciproc Blue files subjected to brushing motion. METHODS: Twenty Reciproc Blue files (R25, VDW, Munich, Germany) were employed for chemical-mechanical preparation in root canals of 3D printed replicas of mandibular molars. The instruments were divided into two groups (n = 10): Group brushing motion, instrumentation with brushing motions; Group without brushing motion , instrumentation without brushing motions. Subsequently, the same instruments underwent cyclic fatigue testing using artificial canals consisti

Advancement in biomedical implant materials-a mini review.

Metal alloys like stainless steel, titanium, and cobalt-chromium alloys are preferable for bio-implants due to their exceptional strength, tribological properties, and biocompatibility. However, long-term implantation of metal alloys can lead to inflammation, swelling, and itching because of ion leaching. To address this issue, polymers are increasingly being utilized in orthopedic applications, replacing metallic components such as bone fixation plates, screws, and scaffolds, as well as minimizing metal-on-metal contact in total hip and knee joint replacements. Ceramics, known for their hardn…

Comparing the performance of a femoral shaft fracture fixation using implants with biodegradable and non-biodegradable materials.

Orthopedic injuries, such as femur shaft fractures, often require surgical intervention to promote healing and functional recovery. Metal plate implants are widely used due to their mechanical strength and biocompatibility. Biodegradable metal plate implants, including those made from magnesium, zinc, and iron alloys, offer distinct advantages over non-biodegradable materials like stainless steel, titanium, and cobalt alloys. Biodegradable implants gradually replace native bone tissue, reducing the need for additional surgeries and improving patient recovery. However, non-biodegradable implant…

Bacterial survival on inanimate surfaces: a field study.

OBJECTIVE: Environmental surfaces may serve as potential reservoirs for nosocomial pathogens and facilitate transmissions via contact depending on its tenacity. This study provides data on survival kinetics of the most important nosocomial bacteria on a panel of commonly used surfaces. Type strains of S. aureus, K. pneumoniae, P. aeruginosa, A. baumannii, S. marcescens, E. faecium, E. coli, and E. cloacae were suspended in 0.9% NaCl solution at a McFarland of 1 and got then plated via cotton swabs either on glass, polyvinyl chloride, stainless steel, or aluminum. Surfaces were stored at regula…

Hydrothermal oxidation of pre-dissolved resorcinol-formaldehyde resins as a new approach to safe processing of spent cesium-selective organic ion-exchangers.

Here we report a new approach to predisposal processing of spent resorcinol-formaldehyde resins (RFR) selective to cesium radionuclides via … iency of HTO of resorcinol and RFR solutions with hydrogen peroxide was investigated in a flow-type stainless steel reactor in the temperature range 165-250 °С and at linear flow rates of 1-3 cm/min. It was demonstrated that HTO allowed efficient resorcinol mineralization using hydrogen peroxide at H2O2: resorcinol molar ratios above 10 at 195 °С and a linear flo …

Оценка вируцидальной эффективности пероксида водорода с точки зрения воздействия вируса желтой лихорадки 17-ДДД для применения в отрасли по производству вакцин.

Цель этого исследования состояла в том, чтобы оценить эффективность ин активации пероксида водорода к штамму вакцины от вируса желтой лихорадки 17-ДДД, используемой для производства вакцины от пониженной желтой лихорадки, в двух матрицах: вакцины от желтой лихорадки (ФГВ) и вирусной подвески желтой лихорадки - активный фармацевтический ингредиент (АПИ). Образцы были высушены на нержавеющей стали и подвергались воздействию жидкости пероксида водорода (HPL) в концентрациях 30, 10, 3 и 1% в течение 20 и 60 минут; и паров пероксида водорода (HPV) в изоляторе. В результате воздействия HPL 30% и 10%

Совпадение в аннотации оригинала
The aim of this study was to evaluate the inactivation performance of hydrogen peroxide to the yellow fever virus 17DD vaccine strain, used … d yellow fever viral suspension - active pharmaceutical ingredient (API). The samples were dried on stainless steel and exposed to hydrogen peroxide liquid (HPL) at concentrations of 30, 10, 3 and 1% for 20 and 60 min; and to hydrogen peroxide vapour (HPV) in an isolator. The exposure to HPL 30 and 10 %, within 20 min, reduced the virus titre at least 3.85 log10 …