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A Survey Study of Patient-Physician Communication and Treatment Decision-Making Preference at Treatment Initiation and After Disease Stabilization in Newly Diagnosed Multiple Myeloma.

INTRODUCTION: We present real-world evidence of patient-physician communication for patients with newly diagnosed multiple myeloma (NDMM) who have not received hematopoietic stem cell transplantation. METHODS: An observational survey study was conducted in Japan (September‒November 2024). Patients with NDMM completed a self-reported 34-item survey (online or paper-based), and hematologists treating patients with multiple myeloma completed a self-reported 18-item survey online. Communication status between patients and physicians and information on patients' treatment expectations, values, emo

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… data | 0 (0) | — Induction regimen b | | D‐MPB | 22 (10.0) | — DLd | 26 (11.8) | — Bd | 42 (19.1) | — Ld | 25 (11.4) | — Other | 72 (32.7) | — Do not remember | 33 (15.0) | — Prefer not to answer/missing data | 0 (0) | — Healthcare attended by patients/physician practice setting | | Cancer center/academia … | 89 (40.5) | 43 (35.8) Community hospitals (national/government hospitals, public hospitals, and general hospitals other than cancer center/academia), medical offices/clinics | 131 (59.5) | 76 (63.3) Other | 0 (0) | 1 (0.8) Prefer not to answer/missing data | 0 (0) | — Work status | | Currently working …

INCREASING THE UPPER AIRWAY SPACE USING ORAL APPLIANCES IN PATIENTS WITH MILD SLEEP APNOEA CAUSED BY STOMATOGNATHIC DYSFUNCTIONS.

INTRODUCTION: Abnormal breathing can be caused by developmental malformations or anatomical variations in the upper airways. Stomatognathic diseases may significantly impair the patency of the upper respiratory tract. Treatment of advanced stomatognathic dysfunctions is difficult due to their multifactorial aetiology, and often involves many phases. Sleep apnoea is one of the most bothersome complications. The mainstay therapeutic strategy relies on modifying the position of the mandible against the maxilla, achieved by using different types of oral appliances. MATERIAL AND METHODS: The study

The evaluation of procedure and treatment outcome in patients with tension pneumothorax.

INTRODUCTION: Tension pneumothorax is a directly criti- cal illness condition. The aim of this study was to evaluate the outcome of tension pneumothorax treatment in trauma patients. MATERIAL AND METHODS: We assessed the results of treat- ment of 22 patients hospitalized for trauma in 2000-2010, in whom at the time of admission tension pneumothorax symptoms were found. This constituted 18% of trauma patients who at the time of admission to the hospital, during the initial examination, were diagnosed with pneumothorax. In the study group there were 17 men and 5 women. The patients' ages ranged

Odontogenous sinus tract to the chin--case report.

This report describes the diagnosis, treatment and follow-up of a rare case of an odontogenic sinus tract to the chin. Despite the absence of caries, fillings, or crown damage, both lower central incisors were involved in a bony lesion. No history of any traumatic facial or dental injury was reported, and no orthodontic treatment with fixed appliances was performed. The findings on panoramic radiograph were incidental--the patient applied to the dental clinic due to a toothache in a lower first molar. The patient's history comprised seven-year-long unsuccessful dermatologic therapy. This inclu

[Motor system physiotherapy of the masticatory organ].

The motor system of the masticatory organ is a complex morphological and functional structure. Its dysfunctions are manifested by various symptoms within the masticatory apparatus and in distant organs. The paper presents a discussion on the physiotherapeutic procedure for the treatment of disorders in the motor system of the masticatory organ. Therapeutic methods are presented, including: massage, trigger point therapy, kinesitherapy, biofeedback, manual therapy, postural re-education, kinesiotaping, physical interventions (TENS, hyaluronidase iontophoresis, ultrasound, laser therapy, and mag

[Dihydropirymidine dehydrogenase (DPD)--a toxicity marker for 5-fluorouracil?].

In proceedings relating to patients suffering from cancer, an important step is predicting response and toxicity to treatment. Depending on the type of cancer, physicians use the generally accepted schema of treatment, for example pharmacotherapy. 5-fluorouracil (5-FU) is the most widely used anticancer drug in chemotherapy for colon, breast, and head and neck cancer. Patients with dihydropyrimidine dehydrogenase (DPD) deficiency, which is responsible for the metabolism of 5-FU, may experience severe side effects during treatment, and even death. In many publications the need for determining t

The use of cortical screw anchorage for closing a space resulting from the loss of a lower molar--a case report.

Orthodontic microscrews are temporary implants providing skeletal anchorage, which may be used for en-masse incisor retraction, as well as for the protraction of posterior segments in order to close spaces without retracting anterior teeth. A patient, aged 16 was reported in whom a miniscrew of 9.5 mm length and 2 mm dimension was inserted distal to the lower left second premolar 2 months after extracting the first molar with periapical bone lesion after failed endodontic treatment. The lower third molar was mesialised using direct anchorage and a power arm to minimize mesial tipping. The spac

Diffuse trauma of the right lobe of the liver successfully treated without resection. Case report.

The victim of a motorcycle frontal crash was treated in a high reference teaching hospital for disruption of the right lobe of the liver (IV grade AAST/Moore). Primary packing, secondary biloma and abscess treatment including papillotomy and biliary stent, led, after 8 months, to cicatrisation of a damaged liver parenchyma. In conclusion, the authors stress that such injuries should be treated in highest level reference centres where all modern noninvasive interventional modalities are available, and that surgical resection is not always the operation of best choice.

[A rare case of exposure to natural psychoactive substances, and difficulties with medicolegal assessment].

An unusual case of exposure to natural psychoactive substances deriving from Datura stramonium (jimsonweed, thorn-apple) is presented in this article. It may be of interest in this case that a hallucinogenic substance was intentionally administered by a third party. An initial assessment in this criminal case was questionable, and resulted from a lack of consideration of toxicological exposure and its possible aftermath. The above-mentioned case demonstrates the necessity of considering all toxicological aspects of the case, even though initial findings seemed to indicate something else.

[Neuroethics: new quality of medical ethics?].

During the last decade there has been a striking growth in interest in ethical issues arising from the development of neurosciences. It was as late as 2002 that the new discipline, called neuroethics, started. It was intended to be a new area of interdisciplinary discourse on moral dilemmas connected with recent advances in, broadly understood, neurosciences. Ten years after its launch neuroethics possesses a distinct body of knowledge and an institutional basis for its further development. As a very young discipline, however, neuroethics is still in a state offlux. Two essential theoretical c

[Mesenteric infarction of the small bowel in the course of portal vein thrombosis - a case report].

Portal vein thrombosis is a rare entity, usually concomitant with hepatic cirrhosis and malignancies. Spontaneous disease occurs very rarely, and it presents with venous small bowel mesenteric infarction, causing intestinal ischaemia extremely rarely. We present a patient who was operated on because of symptoms and signs of "acute abdomen" and in whom segmental ischaemia of the small bowel and mesenteric thrombosis were found intraoperatively. The correct diagnosis, mesenteric infarction of the small bowel in the course of portal vein thrombosis, was made after performing an abdominal computer

[Patients functioning after surgical treatment for Perthes disease].

INTRODUCTION: Perthes disease appears in children and affects hip joints. The proximal head of the femur is damaged, which results in deformation of the femoral ball and loss of its spherical shape. Instant diagnosis and introduction of treatment is crucial for maintaining the femoral head in the hip socket, which facilitates recovery to its spherical shape. To assess the quality of life of patients who have undergone surgical treatment. The factors examined were: state of functioning and occurrence of pain in affected hip joint. MATERIAL AND METHODS: 61 participants underwent the examination

[Syphilis in the past and present].

Syphilis is a specific inflammation which is extremely difficult to clearly diagnose in archaeological material. The origin of this disease is unclear. Most proponents hold the view that it comes from America, and that it was transmitted to Europe by sailors travelling with Columbus. In addition to the thesis of the American origin of syphilis is a suggestion that a mild form of syphilis existed in Europe before Columbus' expeditions. This form, until the end of the fifteenth century, began to spread epidemics. In Poland, the first officially reported case of the disease was described in 1495.

Dynamic renal scintigraphy with 99mTc-DTPA for the assessment of renal function after therapy of acute lymphoblastic leukemia in children.

INTRODUCTION: Acute lymphoblastic leukemia (ALL) and its treatment may lead to impairment of kidney function. The aim of the present study was to evaluate kidney function in children after treatment of ALL. We used our 99mTc-DTPA (diethylene triamine pentaacetic acid labeled with 99mTc) dynamic scintigraphy protocol. MATERIAL AND METHODS: The study group consisted of 48 ALL patients, aged 79-275 months, in complete remission (mean duration 51 months). Treatment was according to the guidelines of the Berlin Frankfurt Münster (BFM) BFM 86 and BFM 90 protocols in 36 (75%) and 12 (25%) children,