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Effects of Carbon Nanomaterials and Aloe vera on Melanomas-Where Are We? Recent Updates.

Melanoma is an aggressive skin cancer that affects approximately 140,000 people worldwide each year, with a high fatality rate. Available treatment modalities show limited efficacy in more severe cases. Hence, the search for new treatment modalities, including immunotherapies, for curing, mitigating, and/or preventing cancer is important and urgently needed. Carbon nanoparticles associated with some plant materials, such as Aloe vera, have shown appealing antineoplastic activity, derived mainly from the compounds aloin, aloe-emodin, barbaloin acemannan, and octapeptide, thus representing new p

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… Studies show that the synthesis of “green” NPs composed of tellurium (TE) associated with Aloe vera (AV-TeNPs), induced a significant reduction in the growth of melanoma cells without causing cytotoxicity to human fibroblasts [ 136 ]. …

Polyphenols: Chemoprevention and therapeutic potentials in hematological malignancies.

Polyphenols are one of the largest plant-derived natural product and they play an important role in plants' defense as well as in human health and disease. A number of them are pleiotropic molecules and have been shown to regulate signaling pathways, immune response and cell growth and proliferation which all play a role in cancer development. Hematological malignancies on the other hand, are cancers of the blood. While current therapies are efficacious, they are usually expensive and with unwanted side effects. Thus, the search for newer less toxic agents. Polyphenols have been reported to po

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… The combination of a chemotherapy formulation of cysteamine-modified cadmium tellurium (Cys-CdTe) quantum dots coloaded with daunorubicin and gambogic acid (GA) nanoparticles displayed a dose-dependent antiproliferative activity on multidrug-resistant lymphoma Raji/DNR cells in vitro and in vivo ( 322 …

Program-Abstracts

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… Balkwill , London, UK Targeting Cancer-Related Inflammation 12:15 Benjamin Sredni , Ramat Gan, Israel Interference with VLA4 and Microenvironmental Interactions by the Tellurium Compound AS101 Results in the Sensitization of AML Cells to Chemotherapy 12:40 Eitan Yefenof , Jerusalem, Israel Sensitizing … We show that the tellurium compound ammonium trichloro(dioxoethylene-O,O’-)tellurate AS101, sensitizes AML cells to ARA-C or DNR. Sensitization of AML cells to chemotherapy by AS101 was similar to that obtained by neutralizing anti VLA antibodies. …

Абстрактный сборник ISEV2022.

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ISEV2025 Резюме книги.

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