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Influences of Infection Prevention and Control Practices for Transmissible Infections Among Operating Room Team Members: A Systematic Review.

AIM: To synthesise evidence on the influences of infection prevention and control practices for transmissible infections among operating room team members. DESIGN: Systematic review. DATA SOURCES: PubMed, CINAHL, APA PsycInfo, Web of Science and Scopus, supplemented by manual searches using Google Scholar and citation tracking. REVIEW METHODS: Databases were searched between March and April 2025, with an updated search undertaken in August 2026. Methodological quality was assessed using the Joanna Briggs Institute (JBI) critical appraisal tools and the Mixed Methods Appraisal Tool (MMAT). D

Engineered near-infrared-responsive PNIPAM/alginate hydrogels for active mechanical stimulation and infection control in diabetic wound healing.

Diabetic wound healing is severely impaired by four core pathological barriers-persistent hyperglycemia, excessive inflammation, bacterial infection, and deficient wound contraction. Herein, we developed a near-infrared (NIR)-responsive antibacterial hydrogel composed of poly(N-isopropylacrylamide), sodium alginate, graphene oxide, and tetracycline hydrochloride (PNIPAM/Alg/GO/TH), in which chitosan serves as an interfacial bridging component that covalently and electrostatically anchors the hydrogel to tissue rather than acting as a bulk matrix constituent. As a natural polysaccharide, sodium

Myeloid cell expression of the VDR and parathyroid hormone control the host response to influenza infection in mice.

INTRODUCTION: Respiratory infections caused by seasonal influenza viruses remain a major global health burden. Vitamin D receptor (VDR) signaling regulates immune responses, but the role of the VDR and its interaction with parathyroid hormone (PTH) in host resistance to H1N1 influenza infection is not understood. METHODS: Global VDR knockout (KO) mice, or myeloid (M) deletion of the VDR (M-VDR KO) and the respective wildtype (WT) littermates were infected with H1N1 influenza virus. Additional experiments treated WT mice with intermittent PTH or vehicle and then infected them with a H1N1 influ

Effect of Video-Assisted Reflective Practice on Infection Control Performance During Oral Hygiene Procedures Performed by Dental Hygienists.

PURPOSE: The dental clinic environment is highly vulnerable to cross-infection from patients' blood and oral fluids. Regular training is vit … domly assigned to one of two groups: the verbal instruction group received conventional training on infection control, while the video-assisted reflective practice group reviewed video recordings of their own clinical performance with guidance from a researcher. Following the educational intervention, all participants repeated the calculus removal procedure, and th …

Disease outbreak preparedness: a baseline assessment of infection prevention and control practice in healthcare facilities in Lagos, Nigeria.

BACKGROUND: Evidence-based infection prevention and control (IPC) measures in healthcare facilities are critical for preventing and containing outbreaks. However, studies have shown inadequate implementation of IPC practices among healthcare facilities in developing countries. To improve practice among healthcare facilities in Lagos, Nigeria, we conducted a baseline assessment of IPC practices in selected healthcare facilities, aimed at identifying strengths and gaps and giving recommendations to promote standard practices. METHODS: We conducted an analytical cross-sectional survey using a mu

Cost-Effectiveness of an Absorbable Antibacterial Envelope for Infection Control in Cardiac Implantable Electronic Device Procedures in Spain.

BACKGROUND: Infections represent the most serious complication associated with cardiac implantable electronic devices (CIEDs). This can result in prolonged hospital stays, high morbidity and mortality, and a significant economic burden for healthcare systems. OBJECTIVES: This study aimed to evaluate the cost-effectiveness of the TYRX absorbable antibacterial envelope for CIED infection prevention from the Spanish Healthcare System perspective. METHODS: A decision tree model with a lifetime horizon was developed to compare standard antibiotic prophylaxis with its combination with TYRX, regard

Factors associated with severe acute respiratory syndrome coronavirus-2 infection in Hohoe Municipality, Ghana: A case-control study.

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection was a major public health challenge globally and in Ghana. To prepare better for future pandemics, an evidence-based understanding of the determinants of coronavirus disease is essential to inform public health guidelines and surveillance. Thus, we identified the factors for SARS-CoV-2 infection in Hohoe Municipality. We conducted a facility-based, sex and age-matched (1:2) case-control study. Cases were persons with a laboratory-confirmed SARS-CoV-2 infection by Reverse Transcription Polymerase Chain Reaction (RT-PCR) or r

Knowledge, Attitudes, and Practices of Infection Prevention and Control Among Healthcare Workers in a Tertiary Hospital in Mauritius.

Background Many hospitalized patients suffer from healthcare-associated infections (HAIs), especially in low- and middle-income countries (LMIC), particularly drug-resistant infections. Infection prevention and control (IPC) is one of the most cost-effective healthcare investments since most HAIs can be prevented by the implementation of effective IPC interventions. This study aims to examine the knowledge, attitudes, and practices (KAP) of healthcare workers (HCW) regarding IPC, given that these factors may shape their compliance with IPC guidelines. Methodology A cross-sectional study was co

Compliance with Infection Prevention and Control Practices Among Allied Health Sciences Students in Jordan: Predictors and Educational Implications.

This study assessed infection prevention and control (IPC) compliance among allied health students during clinical practices and explored it … ecurring, practical IPC training into allied health curricula may enhance compliance and strengthen infection control in clinical education.

Multicenter Point-Prevalence Study of Carbapenem-Resistant Klebsiella spp. in Türkiye: Epidemiology, Antimicrobial Resistance, and Infection Control Practices.

BACKGROUND: Carbapenem-resistant Klebsiella spp. have emerged as major healthcare-associated pathogens worldwide, posing significant therapeutic and infection control challenges. Despite the growing burden of antimicrobial resistance, contemporary multicenter epidemiological data regarding carbapenem-resistant Klebsiella spp. in Türkiye remain limited. This study aimed to determine the culture-based prevalence of carbapenem-resistant Klebsiella spp. and to describe the clinical, microbiological, and institutional characteristics associated with these organisms. MATERIALS AND METHODS: This mul…

Digital Twins for Hospital and Healthcare Operations: A Systematic Review of Resource Allocation, Infection Control, and Workflow Optimization.

The incorporation of Digital Twins (DT) into the healthcare industry marks a revolution in terms of adopting a more proactive and personalized approach towards patient care. The increasing complexity of technological tools employed within the healthcare environment leads to assessing the potential impacts of these digital models in collaboration with AI and IoT for increased efficiency and improved results. In this context, this study offers a systematic review of existing research regarding DTs in the field of healthcare, with specific consideration of hospital applications. An extensive lite

Incidence and Independent Risk Factors of Spinal Infection After Vertebral Augmentation: A Multicenter Propensity-Matched Case-Control Study.

OBJECTIVE: This study aimed to determine the incidence of spinal infection after vertebral augmentation (SIAVA) and identify its independent risk factors. METHODS: This multicenter, retrospective case-control study included patients who underwent percutaneous vertebral augmentation (PVA) for osteoporotic vertebral compression fractures at 4 centers between January 2015 and December 2021. Each SIAVA case was matched with 3 controls using propensity score matching based on demographic and clinical variables. LASSO (least absolute shrinkage and selection operator) regression was used for variabl

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… Potential residual confounding due to center-level differences (e.g., surgical technique, perioperative management, infection control) was therefore unavoidable. Future large-sample, prospective studies are needed to validate our findings across different medical centers. … Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee Am J Infect Control 1999 27 97 132 quiz 133-4; discussion 96 10196487 13 He Y Ke Z Advances in the diagnosis and treatment of spinal infection after vertebral augmentation Adv Clin Med 2025 15 523 …

Impact of intraoperative hemostatic material placement on intra-abdominal infection control in acute appendicitis: a retrospective cohort study.

OBJECTIVE: To evaluate the impact of sodium carboxymethyl cellulose (SCMC)-based absorbable hemostatic gauze on postoperative infectious outcomes in emergency laparoscopic appendectomy (LA) for acute appendicitis. METHODS: A retrospective analysis of 184 patients undergoing emergency LA at General Surgery Department of Beijing Fengtai You'anmen Hospital (Collaborative Hospital of Peking University First Hospital Medical Alliance) from January 2024 to March 2025 was conducted. All consecutive patients were included without selection based on disease severity. Patients were divided into two gro

Genetic diversity and relatedness of Candida albicans isolates from humans and animals in Iran: implications for infection control.

INTRODUCTION: Candida species are known to be a major cause of fungal infections in both humans and animals worldwide. Understanding the local epidemiology and genetic diversity of Candida albicans is essential for effective control and prevention of infections on a global scale. In this study, we aimed to evaluate the genetic relatedness between human and animal isolates of Candida albicans in Iran. METHODS: Thirty-six isolates of C. albicans were obtained from both human and animal sources and were subjected to random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) using thre

Maternal, Behavioral, and Environmental Factors Associated with Toxoplasma gondii Infection in Pregnancy in Italy: A Case-Control Study.

Background: Congenital toxoplasmosis remains a significant cause of fetal morbidity worldwide. This case-control study aimed to identify sociodemographic, dietary, and behavioral factors associated with Toxoplasma gondii infection during pregnancy in Italy by comparing infected women with seronegative controls, and to evaluate modifiable risk behaviors and treatment-related outcomes among affected patients. Methods: This case-control study included 201 pregnant women (100 with T. gondii infection and 101 seronegative controls). Participants completed a structured questionnaire on sociodemograp

Factors driving increases in Clostridioides difficile infection rates in England: a national case-control study, 2019 to 2024.

BACKGROUNDNumbers of Clostridioides difficile infections (CDI) in England have risen since 2021, but for unclear reasons.AIMThis study's objective was to understand factors driving CDI increases, and their relative impact.METHODSWe conducted a case-control study in England from 2019/20 to 2023/24, with CDI case data linked to hospitalisation episodes. Controls were non-CDI related hospitalisation episodes. A logistic regression model estimated odds ratios (ORs) for primary care prescribing, comorbidities, demographic factors, region and testing rates. To assess temporal changes, the model was

Effect of Repeated Education on ICU Nurses' Knowledge and Performance in MDRO Infection Control: A Pretest-Posttest Study.

BACKGROUND: Multidrug-resistant organisms (MDROs) pose a serious threat to patient safety in intensive care units (ICUs), where invasive procedures and extensive antibiotic use elevate the risk of transmission. Although educational interventions can enhance infection control compliance, their effects often decline over time. AIM: To evaluate the effectiveness and sustainability of a repeated education programme on ICU nurses' knowledge and performance related to MDRO infection control. STUDY DESIGN: A one-group pretest-posttest study. RESULTS: Forty-three ICU nurses received three monthly 5…

Outcomes of a Needs Assessment: Informing the Development of an Infection Prevention and Control Toolkit for Missouri Schools.

Effective infection prevention and control (IPC) in schools is vital for student and staff health, yet current resources often fall short, exhibiting a narrow focus, overemphasis on COVID-19, and fragmented implementation, excluding school nurses. This manuscript details a comprehensive needs assessment conducted with Missouri school staff and subject matter experts. Through existing data review, listening sessions, and interviews, the assessment identified critical gaps in IPC training, preferred delivery methods (e.g., self-paced online modules and multimodal formats), and distinct resource

Risk factors for catheter-associated urinary tract infection in an intensive care unit: a matched case-control study.

OBJECTIVE: Catheter-associated urinary tract infections (CAUTIs) are common healthcare-related infections in intensive care units (ICUs). This study investigated the risk factors for CAUTIs in critically ill patients. METHODS: This study was a single-centre, retrospective, matched case-control study of patients undergoing indwelling catheterization in the ICU from December 1, 2016, to October 31, 2021. Patients with catheterizations were matched 1:4 with controls that were hospitalized in the ICU during the same period (with a difference in admission time of no more than two months). RESULTS