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Positive impact of a shelter-based hepatitis B vaccine program in homeless Baltimore children and adolescents.

Homeless youth are at increased risk for hepatitis B virus (HBV) infection and HBV vaccine coverage is poor in this group. The purpose of our study was to determine if a shelter-based HBV vaccine program in children and adolescents 2-18 years of age with a randomized controlled trial using a culturally appropriate HBV video could increase HBV vaccine coverage rates. Subjects were randomized to an 8 min HBV video or a control, smoking prevention video. Before exposure to the videos, HBV knowledge, and demographics were assessed in caregivers and adolescents. HBV vaccine no. 1 was offered to all

Серологические доказательства по Рикитсийскому тифу и эрлихиальному агенту в Норвегии крыс из Балтимора, Мэриленд, США.

С апреля по ноябрь 2005 года мы показывали сыворотку 90 норвежских крыс, попавших в ловушку в Восточном Балтиморе, штат Мэриленд, США, на антитела против Рикитцевского тифа и чаффиниса Эрлихии. Шесть крыс имели положительные тиры > или = 1:64 против R. tyhi и не отреагировали на R. akari. Кроме того, четыре крысы имели трансреактивные антитела с титерами > или = 1:64 против чаффиниса Ehrlichia. Сера из этих крыс также реагировалась с Anaplasma fhagocytophilum или Ehrlichia muris. Наши данные свидетельствуют о том, что агент тиф и эрлихиальных агентов циркулирует в норвежской крысиной популяции

Совпадение в аннотации оригинала
We screened serum from 90 Norway rats trapped in East Baltimore, Maryland, USA, from April to November 2005 for antibodies against Rickettsia typhi and Ehrlichia chaffeensis. Six rats had positive titers of > or = 1:64 against R. typhi and did not react with R. akari. In addition, four rats had cross-reactive antibodies with titers of > or = 1:64 against Ehr…

Proceedings of the Baltimore smooth muscle meeting: identifying research frontiers and priorities for the lower urinary tract.

PURPOSE: The myocyte is a major parenchymal cell of the lower urinary tract (LUT) in men and women. Significant phenotypic diversity ensures … seases/disorders will continue to increase in an ever aging American population. The purpose of the Baltimore Smooth Muscle Meeting was to begin to identify some research frontiers and priorities. MATERIALS AND METHODS: A 1-day conference of some of the leading world experts in smooth muscle research was held at American Urological Association headquarters …

Risk factors associated with antibodies to leptospires in inner-city residents of Baltimore: a protective role for cats.

Leptospiral antibody prevalence was 16% in residents of Baltimore. Seropositivity was associated with age, gender, race, and bird ownership, reduced the antibody risk associated with age and race from odds ratios (95% confidence interval) of 3.3 (2.0, 5.5) and 3.3 (1.1, 9.3), respectively, to the baseline level. These data establish the high prevalence of leptospiral antibody in Baltimore and suggest a protective role for cats in reducing the risk of human infection.

Beyond Individual Risk: A Qualitative Exploration of Intersectional HIV Vulnerabilities Among Black Cisgender Women in Baltimore.

Black cisgender women in the USA experience compounded challenges in protecting themselves from HIV. While prevention efforts often focus on individual-level behaviors, structural and contextual factors critically shape HIV vulnerability and access to care. We conducted qualitative in-depth interviews between October 2021 and April 2023 with 26 Black cisgender women aged 18 to 44 who reported inconsistent condom use and vaginal or anal sex with a male partner in the past 6 months. We used a combined inductive and deductive approach to analyze the data and presented illustrative themes across B

Baltimore oral epidemiology, disease effects, and HIV evaluation study (BEEHIVE) study protocol: a prospective cohort study.

BACKGROUND: As antiretroviral therapy has become widely available and highly effective, HIV has evolved to a manageable, chronic disease. Despite this health advancement, people living with HIV (PLWH) are at an increased risk for age-related non-communicable diseases (NCDs) compared to HIV-uninfected individuals. Similarly, PLWH are at an increased risk for selected oral diseases. PLWH with a history of injecting drugs experience an even greater burden of disease than their counterparts. The overall objective of the Baltimore Oral Epidemiology, Disease Effects, and HIV Evaluation (BEEHIVE) stu…

Syphilis Diagnosis After a Chlamydia, Gonorrhea, or HIV Diagnosis Among Reproductive-Aged Women in Baltimore, MD.

BACKGROUND: Syphilis incidence is increasing among reproductive-aged women, and previous sexually transmitted infections (STIs) are a risk factor for subsequent STIs. This study aimed to determine syphilis incidence after a chlamydia, gonorrhea, or HIV diagnosis, and identify characteristics associated with higher syphilis incidence rates among reproductive-aged women in 1 mid-Atlantic city. METHODS: A retrospective cohort of 85,113 chlamydia, gonorrhea, and HIV diagnoses occurring between 2009 and 2021 and among women aged 13 to 50 years was constructed using public health surveillance data.

Prevalence and correlates of SARS-CoV-2 seropositivity among people who inject drugs in Baltimore, Maryland.

BACKGROUND: SARS-CoV-2 serosurveys can help characterize disparities in SARS-CoV-2 infection and identify gaps in population immunity. Data on SARS-CoV-2 seroprevalence among people who inject drugs (PWID) are limited. METHODS: We conducted a cross-sectional study between December 2020 and July 2022 among 561 participants in the AIDS Linked to the IntraVenous Experience (ALIVE) study-a community-based cohort of current and former PWID in Baltimore, Maryland. Serum samples were assayed for infection-induced anti-nucleocapsid (anti-N) and infection and/or vaccination-induced anti-spike-1 (anti-…

Characterizing Health Care Access among Cisgender Female Sex Workers with Substance Use Histories in Baltimore, Maryland.

Cisgender female sex workers (FSW) have low rates of health care utilization and persistent health disparities. The study uses baseline data from a structural intervention to understand health care access with cisgender FSW with substance use histories (N=370) in Baltimore, Maryland. The four outcome categories measuring health care access in the past six months were: no health care use/barrier to care (16% of sample), no use/no barrier (24%), use/barrier (25%), use/no barrier (36%, most able to access care). Using multinomial logistic regression, we found client-perpetrated violence, depressi…

More than just availability: Who has access and who administers take-home naloxone in Baltimore, MD.

BACKGROUND: Fatal opioid overdose is a pressing public health concern in the United States. Addressing barriers and augmenting facilitators to take-home naloxone (THN) access and administration could expand program reach in preventing fatal overdoses. METHODS: THN access (i.e., being prescribed or receiving THN) was assessed in a Baltimore, Maryland-based sample of 577 people who use opioids (PWUO) and had a history of injecting drugs. A sub-analysis examined correlates of THN administration among those with THN access and who witnessed an overdose (N = 345). Logistic generalized estimating e…

Where does the neighborhood go? Trust, social engagement, and health among older adults in Baltimore City.

Trust is often cited as a necessary predecessor of social engagement, and a public-health good. We question those suppositions through analysis of the life histories of lower-income older adults aging in place in Baltimore. These people desired to continue living independently, but also expressed a complex mix of trust and mistrust in their neighbors, neighborhoods, and broader environments. This was the product of interrelated processes of multilevel physical and social changes over time and space - and, we argue, often featured a "healthy mistrust" that pushed participants to pursue personal…

Substance Use Treatment Retention after Redesign of a Comprehensive Addiction and Pregnancy Program in Baltimore, Maryland.

INTRODUCTION: Substance use disorder (SUD) is a significant cause of morbidity and mortality among perinatal people. Integrated perinatal SU … natal people aged 18+ years admitted to an integrated intensive outpatient SUD treatment program in Baltimore, Maryland, between March 8, 2021, and June 11, 2025. Negative binomial regression was used to examine the association between the program redesign and length of treatment, and logistic regression was used to examine associations between program rede …

Development of a Locator Tool and Protocol to Support People Living With HIV in Baltimore: A Quality Improvement Project.

Retaining people with HIV (PWH) in medical care is crucial to ending HIV as an epidemic. Many PWH in Baltimore also experience high rates of substance use, mental health disorders, and homelessness, making it difficult to locate and engage them in care. In our hospital-to-community transitional care program for PWH, 50% of clients were lost to follow-up. To increase the percentage of engaged patients, we developed a locator tool and protocol detailing patient's social and personal information, to be used when clients could not otherwise be located. We obtained completed locator tools on 85% of…

Physical activity complexity, cognition, and risk of cognitive impairment and dementia in the Baltimore Longitudinal Study of Aging.

INTRODUCTION: Studies on physical activity (PA) and dementia mainly focus on activity quantity or intensity. Yet PA requires neuro-coordination of movement, and it is unclear whether complexity of daily activity varies by cognitive status. Thus, we examined the association between PA complexity, using multiscale entropy, and cognitive function, mild cognitive impairment (MCI), and dementia in older adults in the Baltimore Longitudinal Study of Aging (BLSA). METHODS: A total of 637 older adults (age 73.9 ± 11.3 years) in the BLSA completed a 7-day wrist-worn accelerometer assessment and neurop…

Baltimore community resident and collaborator perspectives on the influence of guaranteed income on health: a formative qualitative study.

BACKGROUND: Given increased interest and investment in guaranteed income initiatives across North America, it is critical to understand the impact of guaranteed income on health, an understudied outcome. As part of Baltimore, Maryland's guaranteed income pilot, we conducted formative research to understand the influence of increased income on health and develop concrete recommendations for implementation and evaluation of the pilot. METHODS: We conducted semi-structured in-depth interviews with Baltimore community residents (n = 8) and community collaborators (n = 8), probing on familiarity w…

Объединение общих инфекций с когнитивными характеристиками в рамках последующей деятельности по исследованию района эпидемиологического лова Балтимора.

ВВЕДЕНИЕ: Растущие данные свидетельствуют о том, что некоторые распространенные инфекции по своей причинно-следственной связи связаны с когнитивным расстройством; однако о бремени множественных инфекций известно меньше. МЕТОДЫ: Мы изучили перекрестную связь между положительными тестами антитела на герпесами, цитомегаловирусом (CMV), вирусом Эпштейн-Барр (EBV), вирусом варицелла-зостера (VZV) и токсоплазмой гонди (TOX) и обследованием штата Минимально-Мантически (MMSE) и задерживали устные отзывы у 575 взрослых в возрасте 41-97 лет по результатам исследования района эпидемологического лова в Ба

Совпадение в аннотации оригинала
INTRODUCTION: Growing evidence suggests that some common infections are causally associated with cognitive impairment; however, less is know … al State Examination (MMSE) and delayed verbal recall performance in 575 adults aged 41-97 from the Baltimore Epidemiologic Catchment Area Study. RESULTS: In multivariable-adjusted zero-inflated Poisson (ZIP) regression models, positive antibody tests for CMV (p = .011) and herpes simplex virus (p = .018) were individually associated with poorer MMSE perfo …

The Baltimore Classification of Viruses 50 Years Later: How Does It Stand in the Light of Virus Evolution?

Fifty years ago, David Baltimore published a brief conceptual paper delineating the classification of viruses by the routes of genome expression. The six "Baltimore classes" of viruses, with a subsequently added 7th class, became the conceptual framework for the development of virology during the next five decades. During this time, it became clear that the Baltimore classes, with relatively minor additions, indeed cover the diversity of virus genome expression schemes that also define the replication cycles. Here, we examine the status of the Baltimore classes 50 years after their advent and …

The Baltimore Buprenorphine Initiative: understanding the role of buprenorphine in addressing heroin addiction in an urban-based community.

Adequate drug treatment for substance users continues to be a challenge for most U.S. cities. To address heroin addiction in Baltimore, the Baltimore Buprenorphine Initiative was implemented as a joint project to promote individualized, patient-centered buprenorphine therapy in conjunction with behavioral treatment to accelerate recovery from opioid addiction. The purpose of this analysis was to explore differences in recovery trajectories predicting length of stay and use this information to predict characteristics that influence an individual's ability to remain in the Baltimore Buprenorphin…

Racial differences in rate of decline in bone mass in older men: the Baltimore men's osteoporosis study.

UNLABELLED: Older black men have higher adjusted BMD than older white men. Using data from a longitudinal cohort study of older men followed … 5 +/- 5.7 and 72 +/- 5.6 years, respectively) who participated in the longitudinal component of the Baltimore Men's Osteoporosis Study returned for a second visit after a mean of 18.8 +/- 6.5 (SD) months and were not taking medications used to treat low bone mass at either visit. BMD was measured at the femoral neck and total hip by Hologic-certified techni …