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NTP Toxicology and Carcinogenesis Studies of Oxazepam (CAS No. 604-75-1) in F344/N Rats (Feed Studies).

Oxazepam and related benzodiazepine drugs are used in the treatment of anxiety. All benzodiazepines currently in use share a number of effects, including sedation, hypnosis, decreased anxiety, muscle relaxation, amnesia, and anticonvulsant activity. Oxazepam and four other benzodiazepines (chlordiazepoxide, chlorazepate, diazepam, and flurazepam) were nominated for study by the Food and Drug Administration (FDA) and by the NIEHS based on their widespread use, use by pregnant women, and the lack of adequate rodent carcinogenicity studies. Oxazepam was evaluated in 14-week and 2-year studies by …

Visual analysis of the research frontiers, hotspots and trends of exercise therapy intervention in tumor-related sleep-wake disorders.

ObjectiveTo systematically understand the research frontiers, hotspots and development trends of exercise therapy in the intervention of tumor-related sleep-wake disorders, and to provide scientific basis for follow-up research.MethodsDownloaded the original research papers on February 26, 2024, from the Web of Science core collection database, on tumor-associated sleep-wake disorders. The data that met the inclusion criteria were imported into the Bibliometric Analysis Platform (http://biblimetric.com), CiteSpace 6.3.R1 and VOSviwer1.6.20 software for visual analysis, and imported into Excel2

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… Studies have found that complementary therapies such as physical exercise (e.g., aerobic exercise, resistance training, running, et al.), psychological counseling (e.g., cognitive behavioral therapy, psychoeducational interventions, et al.), and psychosomatic interventions (e.g., yoga, mindfulness, hypnosis …

Proceedings of Réanimation 2020, the French Intensive Care Society International Congress.

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Massage, reflexology and other manual methods for pain management in labour.

BACKGROUND: Many women would like to avoid pharmacological or invasive methods of pain management in labour, and this may contribute towards … er point therapy, myotherapy and zero balancing. We excluded trials for pain management relating to hypnosis, aromatherapy, acupuncture and acupressure; these are included in other Cochrane reviews. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed trial quality, extracted data and checked data for accuracy. We contacted trial author …

Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.

Glycyrrhetinic Acid and its salts and esters and Glycyrrhizic Acid and its salts and esters are cosmetic ingredients that function as flavor … increase (at 238.8 and 679.9 mg/kg day(-1)) in sternebral variants in a study using rats. Sedation, hypnosis, hypothermia, and respiratory depression were seen in mice given 1250 mg/kg Glycyrrhetinic Acid intraperitoneally. Rats fed a powdered diet containing up to 4% Ammonium Glycyrrhizate had no treatment related effects in motor function tests, but acti …

Proceedings of Reanimation 2021, the French Intensive Care Society International Congress.

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Palliative Care and the Management of Common Distressing Symptoms in Advanced Cancer: Pain, Breathlessness, Nausea and Vomiting, and Fatigue.

Good symptom management in oncology is associated with improved patient and family quality of life, greater treatment compliance, and may even offer survival advantages. With population growth and aging, the proportion of patients with multiple symptoms-both related and unrelated to their cancer-is anticipated to increase, supporting calls for a more routine and integrated approach to symptom management. This article presents a summary of the literature for the use of symptom assessment tools and reviews the management of four common and distressing symptoms commonly experienced by people with

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… small-to-moderate effect (SMD, −0.38; 95% CI, −0.72 to −0.04), although some studies feature a high risk of bias, including inadequate randomization, and the anxiety-relieving effect is stronger. 131 There is insufficient evidence for complementary and alternative medicines, including acupuncture and hypnosis …

Optimizing Care: Integrative Oncology in Myeloproliferative Neoplasm.

Purpose of reviewMyeloproliferative neoplasm (MPN) burdens the lives of those affected. MPN patients endure significant impacts on their physical, psychological, and social well-being. While pharmacological interventions offer some disease and symptom control, they often have unfavorable side effects. This review explores the potential of Integrative Oncology (IO) therapies in managing MPNs and their associated symptoms.Recent findingsIO is dedicated to augmenting conventional treatments through integrating interventions targeting the mind, body, nutrition, supplements, and other supportive ca

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… In the context of MPN, research indicates an increased prevalence of complementary therapies, with statistics revealing the use of massage (28.4%), acupuncture (19.3%), chiropractic (16.2%), aroma therapy (8.6%), homeopathy (6.3%), reiki (5.8%), Ayurveda (2.8%), and hypnosis (2%) among MPN patients [ …

ICIMH 2022 Abstracts

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… Data was pulled for fiscal years 2020 through 2021 and included: chiropractic care, acupuncture, biofeedback, neurofeedback, clinical hypnosis, massage therapy, meditation (specifically MBSR), Tai Chi/qigong, and yoga. … Results: Referrals increased for all approaches from FY20-21 shown as (FY20; FY21): chiropractic (104,197; 197,357), acupuncture (59,787; 100,908), massage therapy (5,021; 17,646), biofeedback (31; 69), neurofeedback (27; 74), clinical hypnosis (10; 40), MBSR (2; 8), Tai Chi (2; 8) and Yoga (1; 2). …

Therapy of unspecific tinnitus without organic cause.

INTRODUCTION: There is a variety of medical and non-medical therapies in practice, which were not evaluated regarding its effectiveness by a … medical treatment can be expected in about 50% of the cases. AD 3: PSYCHOLOGICAL THERAPY PROCEDURES Hypnosis did not show positive effectiveness. With regard to biofeedback it can be concluded that this method can be effective in individual cases, however regarded as unreliable from missing reproducibility. Neurobiofeedback could prove that it had a positi …

Clinical Practice Guidelines for Menopause: An Executive Summary and Recommendations: Indian Menopause Society 2026.

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… MHT: The most effective treatment for VMS is MHT (Grade A), [59,60] and low-dose combined oral contraceptives (COCs) may be used when contraception is needed (Grade C). [61-63] Other options are TLM, complementary and alternative therapies, cognitive behavioral therapy (CBT), hypnosis, and nonhormonal …

Painful boney metastases.

Boney metastasis may lead to terrible suffering from debilitating pain. The most likely malignancies that spread to bone are prostate, breast, and lung. Painful osseous metastases are typically associated with multiple episodes of breakthrough pain which may occur with activities of daily living, weight bearing, lifting, coughing, and sneezing. Almost half of these breakthrough pain episodes are rapid in onset and short in duration and 44% of episodes are unpredictable. Treatment strategies include: analgesic approaches with "triple opioid therapy", bisphosphonates, chemotherapeutic agents, ho

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… These may include: physical medicine approaches, tai chi, yoga, stretching modalities, heat, cold, galvanic ultrasound, behavioral medicine approaches, cognitive behavioral therapy, mediation, hypnosis, relaxation techniques, guided imagery, and acupuncture. …

Текущая роль физиотерапии в системном свето-хайне (AL) амилоидозе и множественной миеломе.

Физиотерапия представляет собой научно обоснованную медицинскую работу, направленную на сотрудничество в диагностике, профилактике и лечении множества болезней и клинических сценариев на всех этапах жизни человека. Его развитие ускорилось за последние годы. two десятилетиями. Сфера физиотерапии постоянно эволютивна. Однако накопленных данных о редких заболеваниях мало. Следует отметить, что возможности для улучшения ситуации и получения потенциальных выгод от сложных заболеваний с низким уровнем заболеваемости также весьма высоки как в виде изолированного подхода, так и в рамках многодисциплин

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… Mind–body exercises (hypnosis, yoga, tai chi, Qigong) may improve physical performance, HRQoL, and mood disorders in cancer patients [ 195 ], but specific information for AL and MM patients is limited. …

Deciphering transcriptomic changes in chemobrain: a comprehensive review.

Chemotherapy-induced cognitive impairments (CICI), colloquially known as "chemobrain," represents a profound and debilitating side effect experienced by a significant number of cancer survivors, impacting their memory, multitasking, and quality of life. This review critically evaluates the molecular mechanisms underlying CICI, with a particular focus on the insights gained from transcriptomic analyses. As cancer incidence rises globally, understanding the complex interplay between chemotherapy agents and their cognitive repercussions becomes increasingly vital. Key mechanisms implicated in CIC

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… Richardson J, Smith J, McCall G, Richardson A, Pilkington K, Kirsch I (2007) Hypnosis for nausea and vomiting in cancer chemotherapy: a systematic review of the research evidence. Eur J Cancer Care 16:402–412 14. …

Psychological problems among cancer patients in relation to healthcare and societal costs: A systematic review.

ObjectiveThis study systematically reviewed the association of psychological problems among cancer patients with healthcare and societal resource use and costs.MethodsPubMed, PsycINFO, and Embase were searched (until 31 January 2021) for studies on psychological symptoms (anxiety, depression, distress, fear of recurrence) or psychiatric disorders (anxiety, depression, adjustment) and healthcare use (e.g., mental, inpatient healthcare), economic losses by patients and family, economic losses in other sectors (e.g., absence from work), and costs. The search, data extraction, and quality assessme

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… FCR FCRI (severity subscale >13) (subscale 0–36) | CAM: professional counselling, massage, physiotherapy, lymphedema therapy, chiropractics, medications for anxiety, or depression, medication for sexual dysfunction, naturopathy, herbs, homeopathy, Reiki, acupuncture, meditation, yoga, hydrotherapy, hypnosis …

The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease.

Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed. During the last five years, the landscape of the pharmacotherapy of SCD has changed dramatically. Currently, 54 drugs have been used or under consideration to use for the treatment of SCD. These fall into 3 categories: the first category includes the four drugs (Hydroxyurea, L-Glutamine, Crizanlizumab tmca and Voxelotor) that have been approved by the United States Food and Drug Administration (FDA) based on suc

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… Examples of nonpharmacologic treatments include meditation, therapeutic massage, transcutaneous electrical nerve stimulation, heat and cold packs, distraction, relaxation, music, guided imagery, self-hypnosis, acupuncture and biofeedback. 13 , 17 Current examples of pharmacologic therapies include the …

Neuropathic cancer pain: What we are dealing with? How to manage it?

Cancer pain is a serious health problem, and imposes a great burden on the lives of patients and their families. Pain can be associated with delay in treatment, denial of treatment, or failure of treatment. If the pain is not treated properly it may impair the quality of life. Neuropathic cancer pain (NCP) is one of the most complex phenomena among cancer pain syndromes. NCP may result from direct damage to nerves due to acute diagnostic/therapeutic interventions. Chronic NCP is the result of treatment complications or malignancy itself. Although the reason for pain is different in NCP and non

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… In a recent trial, intrathecal infusion therapy was not found to be beneficial. 172 Cognitive–behavioral interventions and mind–body therapies (relaxation, imagery, hypnosis, and biofeedback) may have a role to play. 173 It is hypothesized that the mechanism of NCP intersects with the pain-relieving …

Cancer cachexia--pathophysiology and management.

About half of all cancer patients show a syndrome of cachexia, characterized by anorexia and loss of adipose tissue and skeletal muscle mass. Cachexia can have a profound impact on quality of life, symptom burden, and a patient's sense of dignity. It is a very serious complication, as weight loss during cancer treatment is associated with more chemotherapy-related side effects, fewer completed cycles of chemotherapy, and decreased survival rates. Numerous cytokines have been postulated to play a role in the etiology of cancer cachexia. Cytokines can elicit effects that mimic leptin signaling a

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… The use of psychological and behavioral interventions (e.g., relaxation, hypnosis, and short-term group psychotherapy) in cancer is increasing and recent studies have suggested that some of these techniques may affect quality of life and, perhaps, survival rates [ 99 ]. …

Резюме МКАРЕ 2023 77th Национальный конгресс " СИААРТИ "

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… However, recent studies have focused on non pharmacological treatments and, among them, virtual reality hypnosis - VRH - (i.e. digital sedation) is an innovative technique that reduces pain and anxiety in clinical practice. … Authors have no conflict of interest REFERENCES Virtual reality hypnosis in the management of pain: Self- reported and neurophysiological measures in healthy subjects Floriane Rousseaux et al. Eur J Pain. 2022;00:1–15. …

Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia.

Prostate cancer (PCa) remains both a global health burden and a scientific challenge. We present a review of the molecular targets driving current drug discovery to fight this disease. Moreover, the preventable nature of most PCa cases represents an opportunity for phytochemicals as chemopreventive when adequately integrated into nutritional interventions. With a renovated interest in natural remedies as a commodity and their essential role in cancer drug discovery, Malaysia is looking towards capitalizing on its mega biodiversity, which includes the oldest rainforest in the world and an estim

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… Hypnosis and relaxation training showed to reduce nausea/vomiting and improve sleep and anxiety, thus increasing resilience to support oncological treatments [ 124 ]. …