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[A case of choroid plexus angioma with subarachnoid hemorrhage--case report (author's transl)].

Authors report a case of choroid plexus angioma of lateral ventricle, in a 42 years old woman, initiated with an episode of subarachnoid hemorrhage. The localization of lesion, in the anterior horn and body of right lateral ventricle, producing primary intraventricular bleeding was revealed by pneumoencephalography, especially polytome pneumotomography. However, it was difficult to find by angiography. Patient was successfully removed angioma and showed good recovery. In review of the literatures, the choroid plexus angioma is found more frequently in children than adults, caused by primary in…

[Electron microscopic study of choroid plexus in experimentally induced hydrocephalic dog (author's transl)].

Choroid plexus in experimentally induced hydrocephalic dogs according to the Wisniewski's method was examined by an electron microscope. Epithelial cell of the choroid plexus appeared in various deformation and formed a marked dilatation of extracellular spaces between apposed two cell membranes and at the basal interdigitation. Dilatation of the extracellular space was more pronounced at the stromal side of the epithelial layer. This finding might be due to anatomical specificities of apposed epithelial cell membranes and not only indicate a disturbance of the CSF secretion. According to the …

Связанные с возрастом различия в структуре Choroid Plexus ассоциируются с изменениями в когниции.

Хороиды-плексус (CP) играют важнейшую роль в поддержании гомеостазиза центральной нервной системы (КНС), производстве цереброспинной жидкости и регулировании поступления конкретных веществ в ЦНС из крови. Дефункция ХП была связана с различными неврологическими и психическими расстройствами, включая болезнь Альцгеймера, болезнь Паркинсона и множественный склероз. В этом исследовании изучается взаимосвязь между структурной целостностью ХП и когнитивным снижением нормативных показателей старения с использованием структурных и передовых методов магнитного резонансного изображения, включая объем ХП

Совпадение в аннотации оригинала
The choroid plexus (CP) plays a critical role in maintaining central nervous system (CNS) homeostasis, producing cerebrospinal fluid, and regulating the entry of specific substances into the CNS from blood. CP dysfunction has been implicated in various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and multiple sc…

VR-10 polypeptide interacts with CD36 to induce cell apoptosis and autophagy in choroid-retinal endothelial cells: Identification of VR-10 as putative novel therapeutic agent for choroid neovascularization (CNV) treatment.

Choroid neovascularization (CNV) is important adverse pathological changes that contributes to the aggravation of hypoxic-ischemic eye diseases, and our preliminary work evidences that the thrombospondin-1 (TSP-1) synthetic polypeptide VR-10 may be the candidate therapeutic agent for the treatment of CNV, but its detailed effects and molecular mechanisms are not fully delineated. In this study, the CNV models in BN rats were established by using the laser photocoagulation method, which were further subjected to VR-10 peptide treatment. The RNA-seq and bioinformatics analysis suggested that VR-…

CHOROIDAL SYNPHLEBIA IN A PATIENT WITH CENTRAL SEROUS CHORIORETINOPATHY.

PURPOSE: The purpose of this study was to describe the choroidal vascular abnormality of conjoined choroidal vessels, synphlebia, in a patient with central serous chorioretinopathy. METHODS: A patient initially referred for pigmentary retinal dystrophy later developed central serous retinopathy and underwent a comprehensive examination with multimodal imaging. RESULTS: A 30-year-old man had an undiagnosed pigmentary retinopathy, and nyctalopia was found to have a dehydrodolichyl diphosphate synthase mutation, confirming a retinitis pigmentosa diagnosis. A year later, he presented with bilate…

CHOROIDAL NEOVASCULARIZATION AFTER MACULAR PLUG SURGERY.

BACKGROUND/PURPOSE: To report choroidal neovascularization (CNV) after macular plug surgery for full-thickness macular hole, detailing four cases-two postinverted internal limiting membrane flap and two posthuman amniotic membrane (hAM) procedures. METHODS: Retrospective, observational small case series. Multimodal imaging investigation comprising optical coherence tomography, optical coherence tomography angiography, and fluoroscein angiography/indocyanine angiography of CNVs after macular plug surgery. RESULTS: In all cases, CNV affected the fovea, with two cases occurring in refractory ma…

Stereotactic radiosurgery in symptomatic circumscribed choroidal hemangiomas.

PURPOSE: To evaluate visual outcomes following stereotactic radiosurgery (SRS) in patients with symptomatic circumscribed choroidal hemangioma (cCH). METHODS: This retrospective study included 30 patients with symptomatic cCH treated with SRS between 2014 and 2025. SRS was performed using either the CyberKnife or ZAP-X platform depending on the treatment period. Visual outcomes were assessed by changes in best-corrected visual acuity (BCVA). A lower score on the logarithm of the minimum angle of resolution (logMAR) scale indicates better vision. RESULTS: The median patient age was 46 years. …

Adipocytes influence choroidal neovascularization via PRDM16.

Neovascular age-related macular degeneration (nAMD) is a prominent cause of blindness in the elderly, characterized by pathological subretinal choroidal neovascularization (CNV). While age and genetics predispose to AMD, modifiable factors such as body adiposity are also thought to contribute. In a mouse model of nAMD, we identified a role for adipose tissue (AT) in exacerbating CNV, specifically pathways in adipocytes expressing Prdm16. Laser-induced CNV in the retina led to heightened expression of genes associated with browning and inflammation in distal inguinal white AT (iWAT). Selective …