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Reconstruction of mandible and surrounding soft tissues in patient with necrotizing fasciitis.

Necrotizing fasciitis is rare in the orofacial region, with fewer than 20 cases reported in the literature. Extension of the disease process to involve the underlying bone has not been previously reported. A patient is presented in whom destruction of superficial skin and fascia, necrosis of a portion of the mandible, and involvement of the parotid gland complicated reconstruction.

Necrotizing fasciitis of the foot caused by an unusual organism, Vibrio vulnificus.

In modern medicine, there are very few infectious disease processes occurring in the foot that can cause death within 48 hr. and have an overall mortality rate of 50% despite appropriate antibiotic and surgical treatment. Such a condition must be regarded as being potentially deadly. The authors report a case of necrotizing fasciitis of the left foot resulting from an unusual organism of Vibrio vulnificus.

Necrotizing surgical infection and necrotizing fasciitis in obstetric and gynecologic patients.

Necrotizing fasciitis (NF) is a rapidly progressive disease characterized by extensive necrosis of the skin, fascia, and subcutaneous tissue, with sparing of the underlying muscle. Diabetes mellitus, Bartholin's gland abscess, and recent surgical procedures (including episiotomy) are factors often found in obstetric and gynecologic patients. Mortality in this group of patients is higher than in the general surgical population. Death is usually due to overwhelming sepsis, renal and respiratory failure, and multiple organ failure. The infections are usually polymicrobial, with alpha-hemolytic st…

Cervical necrotizing fasciitis: two case reports and review of the literature.

Necrotizing fasciitis is a rapidly progressive mixed-organism infection that, in the neck, involves the superficial and deep cervical fascia. Underestimation of this complication of a "minor head and neck infection" can delay diagnosis and treatment of this often fatal disease process. Thirty-five cases of necrotizing fasciitis involving the neck have been reported previously. Two new cases of cervical necrotizing fasciitis and a review of previously reported cases are presented. Management is discussed. Early diagnosis is critical. Antibiotic therapy and prompt, aggressive surgical interventi…

Necrotizing fasciitis: a clinical, microbiologic, and histopathologic study of 14 patients.

We studied the clinical, microbiologic, and histopathologic findings from 14 patients with necrotizing fasciitis; also tissue obtained at autopsy was available from six patients. In all cases, material cultured was positive for multiple organisms, including Clostridia and fungi; organisms were identified by histochemical staining of tissue sections in 12 of 14 cases. The histologic pattern comprised edema, necrosis, and inflammation of skin, subcutaneous fat, and fascial tissue. Hyalin necrosis of sweat glands was observed in five patients. Thrombosis of vessels at all levels was a prominent f…

Vibrio vulnificus necrotizing fasciitis presenting with compartmental syndrome of the hand.

Vibrio vulnificus necrotizing fasciitis is an unusual clinical problem. When it presented as a compartment syndrome, the picture was obscured. We report a rare case of such a presentation. A below-elbow amputation was performed and the patient recovered.

Blood coagulation and fibrinolytic systems in patients with erysipelas and necrotizing fasciitis.

Necrotizing fasciitis (NF) is a skin infection caused by a group A streptococci, resulting in an erythematous lesion with cyanosis and vesicles or bullae leading to gangrene. The condition is prostrating and often accompanied with cerebral confusion. A table of diagnostic scores is given to differentiate initial symptoms and signs of NF from erysipelas (E). Assays of blood coagulation and fibrinolysis together with routine laboratory examinations were made in 12 patients with NF on admission to the hospital and they were compared with similar analyses of 5 patients with E. The NF and E patient…

Eosinophilic fasciitis: report of a case with features of connective tissue diseases.

A patient suffering from eosinophilic facsiitis is described and the literature reviewed. The original description of eosinophilic fasciitis was that of a benign scleroderma-like disease with eosinophilia, hypergammaglobulinemia and diffuse thickening and inflammation of the fascia and subcutaneous tissue. Our patient like a few others, presented additional findings, namely, Raynaud's phenomenon and mild myhositis. She is the first patient described with Sjögren's syndrome. It is important that eosinophilic faciitis be recognized clinically because it seems to be a benign and treatable entity.

Eosinophilic Fasciitis связан с Multieloma: Case Report and Review of the Licture

Резюме: Эосинофильный фаскит является редким фиброзным расстройством мышечной фасии, характеризующимся эритемой, продолжительностью, отеком и нежностью, затрагивающими конечности на двусторонней основе. Она может быть связана с различными гематологическими расстройствами как доброкачественного, так и злокачественного спектра. Доклад КАСЕ: Мы сообщаем о случае эозинофильного фаскита у пациента мужского пола с задержкой диагноза из-за редкости заболевания. Он соответствовал предложенным диагностическим критериям, и дальнейшие исследования показали, что у Ига множественные миеломы с плохим прогно

Совпадение в аннотации оригинала
Abstract BACKGROUND : Eosinophilic fasciitis is a rare fibrosing disorder of the muscle fascia characterized by erythema, induration, oedema, and tenderness affecting the extremities bilaterally. It may be associated with different hematological disorders of both benign and malignant spectrum. CASE REPORT: We report a case of eosinophilic fasciitis in a male…

Pedicled Supraclavicular Flap Reconstruction Following Cervicofacial Necrotizing Fasciitis: A Case Report.

Cervicofacial necrotizing fasciitis is a life-threatening surgical emergency associated with significant morbidity and mortality, requiring early diagnosis and aggressive multimodal management. Reconstruction of the resulting soft tissue defects represents an additional challenge, particularly in resource-limited settings where microsurgical infrastructure may not be available. We report the case of a 42-year-old man who developed cervicofacial necrotizing fasciitis secondary to an odontogenic infection. Management consisted of broad-spectrum antibiotic therapy, early surgical debridement, and…

Necrotizing Fasciitis Camouflaging As Cellulitis: A Case Report Highlighting Diagnostic Pitfalls.

Necrotizing fasciitis (NF) is a rapidly progressive, life-threatening soft tissue infection that is often misdiagnosed in its early stages due to clinical similarities with cellulitis. Early recognition and prompt surgical intervention are essential to reducing morbidity and mortality. This report presents one case of NF initially manifesting as cellulitis in a patient with multiple risk factors, including intravenous drug use and recent incarceration. Despite initial antibiotic therapy and transient clinical improvement, the patient experienced worsening pain and systemic symptoms. Imaging id…

Emphysematous pyelonephritis-related delayed abdominal wall necrotizing fasciitis: A case report.

RATIONALE: Emphysematous pyelonephritis (EPN) is a severe, gas-forming renal infection typically associated with diabetes mellitus. Necrotizing fasciitis (NF) is a rapidly progressive soft tissue infection with significant morbidity. Although concurrent EPN and NF have been described, delayed NF arising years after previously treated EPN is exceedingly rare. This report highlights a unique case of abdominal wall NF secondary to a chronic infectious pathway originating from prior EPN. PATIENT CONCERNS: A 55-year-old woman with poorly controlled type II diabetes mellitus initially presented wit…

Successful treatment of necrotising fasciitis following cobra bite: a case report.

Necrotising fasciitis following cobra envenomation is an infrequent but life-threatening complication. We report a case of a 72-year-old woman from Khotang who developed a rapidly progressive, discharging wound on her right foot 3 days after sustaining a cobra bite. Initially treated at a local snakebite center with 30 vials of antivenom, she later presented with tachycardia, low-grade fever, and leukocytosis. Local tissue culture revealed Streptococcus pyogenes, prompting escalation of antibiotics to Piperacillin-Tazobactam. The ensuing extensive tissue necrosis, driven by venom cytotoxicity,…

Fulminant necrotizing fasciitis secondary to Aeromonas dhakensis infection: a case report.

BACKGROUND: Necrotizing fasciitis (NF) is a kind of rapidly destructive soft tissue infection with an unfavorable prognosis. It is usually caused by highly virulent bacteria. Recently, the incidence of NF caused by atypical opportunistic pathogens has been increasing. Aeromonas dhakensis is increasingly emerging as a new, highly virulent, biofilm-producing, and multidrug resistant cause of soft tissue infection. The current strains of A. dhakensis are causing increasingly severe disease, with delayed diagnosis and treatment. CASE PRESENTATION: We report a rare case of NF caused by A. dhakensi…

Advances in Necrotizing Fasciitis Animal Models: Current Trends and Future Perspectives.

Necrotizing fasciitis (NF) is a rapidly progressive soft tissue infection with high morbidity and mortality, yet its pathophysiology remains incompletely understood. Animal models are indispensable for dissecting disease mechanisms and testing therapeutic interventions, yet their translational relevance varies across species and experimental approaches. This review critically evaluates NF models in rodents, zebrafish, rabbits, pigs, and non-human primates, highlighting their relative strengths in replicating immunopathology, systemic dissemination, and biofilm-driven persistence. We examine me…

Distinguishing Periorbital Necrotizing Fasciitis from Orbital Cellulitis Using Admission Laboratory Values.

PURPOSE: To evaluate the diagnostic performance of 7 composite complete blood count-derived indices-systemic immune-inflammatory response index, systemic immune-inflammation index, systemic inflammation response index, platelet-to-lymphocyte ratio, platelet-to-monocyte ratio, hemoglobin-to-platelet ratio, and hemoglobin-to-lymphocyte ratio-in distinguishing periorbital necrotizing fasciitis (PNF) from orbital cellulitis at initial emergency department presentation. METHODS: This retrospective case-control study reviewed adult patients diagnosed with either PNF or orbital cellulitis. Diagnoses…