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Economic burden of locoregional and metastatic relapses in resectable early-stage non-small cell lung cancer in Spain.

BACKGROUND: There are scarce data of the costs of non-small cell lung cancer (NSCLC) recurrence in Spain. The objective of this study is to assess the economic burden of disease recurrence, for both locoregional and/or metastatic relapses, after appropriate early-stage NSCLC treatment in Spain. MATERIALS AND METHODS: A two-round consensus panel of Spanish oncologists and hospital pharmacists was conducted to collect information on patient's flow, treatments, use of healthcare resources and sick leaves in patients with relapsed NSCLC. A decision-tree model was developed to calculate the econom…

Downsizing and purchases of psychotropic drugs: A longitudinal study of stayers, changers and unemployed.

BACKGROUND: The evidence is insufficient regarding the association between organizational downsizing and employee mental health. Our aim was to analyze trajectories of prescribed sedatives and anxiolytics with a sufficiently long follow-up time to capture anticipation, implementation and adaption to a downsizing event among stayers, changers and those who become unemployed compared to unexposed employees. METHOD: Residents in Sweden aged 20-54 years in 2007, with stable employment between 2004 and 2007, were followed between 2005 and 2013 (n = 2,305,795). Employment at a workplace with staff

Eyeblink recognition improves fatigue prediction from single-channel forehead EEG in a realistic sustained attention task.

OBJECTIVE: A passive brain-computer interface recognizes its operator's cognitive state without an explicitly performed control task. This technique is commonly used in conjunction with consumer-grade EEG devices for detecting the conditions of fatigue, attention, emotional arousal, or motion sickness. While it is easy to mount the sensors in the forehead area, which is not covered with hair, the recorded signals become greatly contaminated with eyeblink and movement artifacts, which makes it a challenge to acquire the data of suitable for analysis quality, particularly in few channel systems

Bariatric and metabolic surgery.

In the beginning of the 21st century obesity still represents health, social and economical threat for most of economically wealthy countries worldwide. Estimated direct costs for obesity and related comorbidities treatment exceed 5% of the total health care costs both in the US and in European Union. However, in addition there are obesity-related indirect costs linked to more frequent work sickness leave, higher unemployment rates and overall lower productivity of obese patients. Surgical treatment of obesity (bariatric surgery) is the most effective long-term treatment modality for those pat

Cost effectiveness of periradicular infiltration for sciatica: subgroup analysis of a randomized controlled trial.

STUDY DESIGN: A subgroup analysis of a prospective, randomized controlled trial was performed. OBJECTIVE: To describe the cost effectivenes … try Low Back Disability Questionnaire, and the Nottingham Health Profile. Data on medical costs and sick leaves also were gathered. Patients were randomized for periradicular infiltration with either methylprednisolone-bupivacaine or saline. The adjusted between-group treatment differences at each follow-up assessment, the number of patients free of leg pain …

Unmet Workplace Support Needs and Lost Productivity of Workers With Systemic Sclerosis: A Path Analysis Study.

OBJECTIVE: Few studies have examined how workplace support can address work productivity loss among individuals with systemic sclerosis (SSc). The objective was to 1) examine the relationship between unmet workplace support needs and work productivity loss among workers with SSc, and 2) determine whether SSc symptom severity, fatigue, active disease periods, and workplace activity limitations mediate the relationship between unmet workplace support needs and work productivity loss. METHODS: A cross-sectional survey was conducted of employed individuals with SSc who were recruited through rheu

Number of Pain Locations as a Predictor of Cause-Specific Disability Pension in Sweden-Do Common Mental Disorders Play a Role?

OBJECTIVE: The aim of this study was to investigate the associations between number of pain locations, common mental disorders (CMDs), and disability pension (DP). METHODS: Survey data in 1998 to 2003 for 27,165 Swedish twins born in 1935 to 1958 were linked to national DP data until 2013. Pain locations were evaluated for back, low back, sciatica, shoulder, or neck pain, and CMDs for lifetime major depression and 1-month anxiety. RESULTS: The number of pain locations was associated with DP in a dose-response manner. One pain location had a hazard ratio of 1.50 (95% confidence interval 1.35

Societal costs and patients' experience of health inequities before and after diagnosis of psoriatic arthritis: a Danish cohort study.

OBJECTIVES: To comprehensively study the comorbidities, healthcare and public transfer (allowance) costs in patients with psoriatic arthritis (PsA) before and after diagnosis. METHODS: Nationwide cohort study, using data from Danish registries from January 1998 through December 2014. A total of 10 525 patients with PsA and 20 777 matched general population comparator (GPC) subjects were included. Societal costs, employment status and occurrence of comorbidities in patients with PsA both before and after diagnosis were compared with GPC subjects. RESULTS: At baseline, patients with PsA had si

Woodworking injuries: a comparative study of work-related and hobby-related accidents.

The primary objective of this study was to describe the injury characteristics and demographics of patients injured during woodworking activities, upon their arrival to the emergency department in a regional of France where this industry is prevalent. The secondary objective was to compare patient and injury characteristics for work-related and hobby-related accidents. A cohort of 87 patients who had suffered a woodworking accident over a two-year period was evaluated; 79 were available for follow-up. The context and circumstances of the accident, nature and location of the injuries and patien

Association of abuse history with symptom severity and quality of life in patients with fibromyalgia.

A high prevalence of abuse has been reported in patients with fibromyalgia. We aimed to examine the association between self-reported abuse history and symptom severity and quality of life (QOL) in 962 patients with fibromyalgia. All patients completed the Fibromyalgia Impact Questionnaire (FIQ) and the Short Form 36 health survey (SF-36). Multivariate regression analyses were performed. In total, 289 patients (30%) reported a history of abuse. Of those who specified abuse types, 161 patients (59%) reported more than 1 type of abuse (36% emotional, 32% physical, 25% sexual, and 7% verbal). Pat

Musculoskeletal impairments in the Norwegian working population: the prognostic role of diagnoses and socioeconomic status: a prospective study of sickness absence and transition to disability pension.

STUDY DESIGN: Population-based, 5-year prospective cohort study. OBJECTIVE: To assess the incidence of musculoskeletal disorders (MSDs) in sickness absence longer than 8 weeks in Norway, and to identify diagnostic and socioeconomic predictors of the transition to disability pension (DP). SUMMARY OF BACKGROUND DATA: MSDs are prevalent and of major concern for sickness absence. Previous epidemiological studies are largely cross-sectional and based on self-reports, often with low response rates, selection, and reporting bias. Prospective studies with physician-verified diagnoses might be a bett

Elevated serum S-100B protein as a predictor of failure to short-term return to work or activities after mild head injury.

Protein S-100B is an established serum marker of primary and secondary brain damage and stroke. A group of patients after mild head injury (MHI) develop post-concussion symptoms that interfere with the ability in the short-term to return to work or undertake certain activities. The aim of this study was to examine the correlation of serum S-100B with short-term outcome after MHI. We studied 100 subjects who were referred to the Emergency Department (ED) after a MHI. All subjects had a GCS of 15 either with or without loss of consciousness (LOC) and/or post-traumatic amnesia (PTA). Serum S-100B

Addressing mental health challenges in clinical practice: a qualitative study to investigate perspectives of international mental health experts.

INTRODUCTION: Mental illnesses are not only associated with the highest level of subjective suffering compared to other chronic diseases but at the same time with a significantly increased morbidity. Especially in industrialized countries, a dramatically increasing proportion of sick leave and early retirement due to mental illness diagnoses is observed, pointing to increased social stress factors and a close association with societal changes and emphasizing challenges to the health care system. The following qualitative study was conducted as part of the establishment of the German Center for…

Использование ресурсов здравоохранения и связанные с этим расходы в течение первого периода 5 Годы после диагностирования и в конце жизни: Общенациональное кохортное исследование пациентов с множественной миеломой в Финляндии.

Как ожидается, в связи со старением населения возрастет бремя, связанное с лечением пациентов с множественной миеломой (ММ). Таким образом, политикам и врачам необходимо целостное представление об использовании ресурсов здравоохранения (ГХРУ) и расходах, связанных с ММ и его лечением для принятия обоснованных решений. Вместе с тем в Финляндии практически отсутствует общенациональная информация о ГКРУ и расходах, связанных с ММ. Цель этого исследования состояла в том, чтобы определить использование ресурсов здравоохранения, модели использования услуг и связанные с этим расходы финских пациентов

Совпадение в аннотации оригинала
BACKGROUND: The burden associated with the treatment of patients with multiple myeloma (MM) is expected to increase due to the aging populat … are contacts by respective national unit costs. For reimbursed outpatient medication and reimbursed sick leave, data on actual costs were collected. All registry data were linked via unique personal identifiers, and follow-up time was up to 5 years. RESULTS: Altogether, 1615 patients were included in the analyses. In the 5-year follow-up period, patients ha …

Machine-learning-based prediction of respiratory flow and lung volume from real-time cardiac MRI using MR-compatible spirometry.

BACKGROUND: Cardiac real-time MRI (RT-MRI) in combination with MR-compatible spirometry (MRcS) offers unique opportunities to study heart-lung interactions. In contrast to other techniques that monitor respiration during MRI, MRcS provides quantitative respiratory data. Though MRcS is well tolerated, shortening of the scanning time with MRcS would be desirable, especially in young and sick patients. PURPOSE: The aim of the study was to predict airflow and lung volume based on RT-MR images after a short learning phase of combined RT-MRI and MRcS to provide respiratory data for subsequent short

Review: Binocular double vision in the presence of visual field loss.

IMPORTANCE: Mild traumatic brain injury (mTBI) may impair the ability to work. Strategies to facilitate return to work are understudied. OB … ork status (working or not working) at each study follow-up milestone. Employer assistance included sick leave, reduced hours, modified schedule, transfer to different tasks, assistive technology, and coaching offered during the first 3 months after injury. RESULTS: Of 435 participants (147 [34%] female; 320 [74%] White; mean [SD] age 37.3 [12.9] years), 25 …

COVID-19 Infection Among Incarcerated Individuals and Prison Staff in Lombardy, Italy, March 2020 to February 2021.

IMPORTANCE: Owing to infrastructural and population characteristics, the prison setting is at increased risk for transmission of SARS-CoV-2 … r of incarcerated individuals placed in quarantine in single or shared isolation rooms, the rate of sick leave by symptomatic and asymptomatic prison staff reported to the prison occupational medicine department on a weekly basis, and the level of overcrowding. MAIN OUTCOMES AND MEASURES: The primary outcome measures were weekly COVID-19 crude case rates, w …

Partial arthroscopic trapeziectomy and stabilisation by ligamentoplasty: Outcomes in patients younger than 60years.

BACKGROUND: Thumb carpometacarpal joint (TCMJ) osteoarthritis is the fourth leading cause of referral to elective hand surgery. None of the … nsion (p=0.06). At last follow-up, the mean NHS was 83.2±19.4 and the mean PRWE was 15.4±17.9. Mean sick leave duration was 5.4weeks (range: 1-24weeks). Only 2 patients, both in manual jobs, were unable to return to work. The radiographs at last follow-up showed the development of moderate TCMJ narrowing in 14 patients and evidence of scapho-trapezio-trapezo …

Economic burden of neural tube defects in Germany.

OBJECTIVE: Failure of closure of the neural tube often leads to serious malformations, including spina bifida, anencephaly and encephalocoel … , rehabilitation, remedies and medical aids, pharmacotherapy use, long-term care and information on sick leave. The analysis was stratified by age group to provide a burden estimate specific to a person's age. To obtain an indicator of incremental burden to the Statutory Health Insurance (SHI), results were compared to the standardized healthcare expenditure …

A survey of violence toward nursing staff in one large Irish Accident and Emergency Department.

INTRODUCTION: Nurses in Ireland are increasingly concerned about the escalating incidence of verbal and physical abuse, particularly in Acci … e hospital, (2) the frequency of such attacks, (3) whether the violence was officially reported and sick leave taken, (4) whether age and experience changed attitudes to violence, or the reporting of it, and (5) the level of staff training, if any, in dealing with violence. METHODS: A wide-ranging questionnaire was designed and confidentially offered to nur …