Результаты поиска

Infectious Diseases

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… Lyme erythema migrans), Treponema pallidum (chancre, secondary syphilis) rickettsial —Rocky Mountain spotted fever, ehrlichiosis, typhus viral exanthem —acute HIV, mononucleosis, rubella, measles, roseola, erythema infectiosum, chickenpox, shingles, coxsackie virus, echovirus fungal — Blastomyces , Coccidioides … Endemic fungal infections include Blastomyces dermatitidis (southeastern states, Manitoba, and Ontario), Coccidioides immitis (southwestern states), and Histoplasma capsulatum (Mississippi, Ohio River valleys, and Quebec) HISTORY —pattern and duration of fever, associated symptoms (cough, dyspnea, …

The Management of Hematopoietic Stem Cell Transplant in People with HIV.

Hematopoietic stem cell transplant (HSCT) is now recognized as a standard treatment option for people with HIV (PWH) who develop high-risk hematologic malignancies. However, the involved polypharmacy can lead to complications from drug interactions and toxicities, affecting the efficacy and safety of chemotherapy and antiretroviral therapy (ART). Managing these patients requires a personalized approach, including the careful selection of ART based on previous therapies and potential interactions, alongside risk assessment for infections. This discussion will address the history of HSCT in PWH

Совпадение в полном тексте источника
… Endemic Fungal Infections Endemic fungal infections such as Histoplasma capsulatum , Coccidioides immitis, and Taloromyces (Penicillium) marneffei are opportunistic in PWH. … serology. ▪ For people with diffuse pulmonary, disseminated, or meningeal disease, suppressive therapy should be continued indefinitely. | ▪ No guidelines for HSCT but consider pre-HSCT. ▪ Primary prophylaxis in those who visit or live in Coccidioides-endemic areas for first 100 days post-HSCT, and …

Olorofim for the treatment of invasive fungal diseases in patients with few or no therapeutic options: a single-arm, open-label, phase 2b study.

BACKGROUND: Only a small number of antifungal therapies for invasive fungal disease (IFD) are currently available, and many pathogens are re … 1, including 22 azole-resistant strains), Lomentospora prolificans (n=26), Scedosporium spp (n=22), Coccidioides spp (n=41), and other fungi (n=12). Successful global response was confirmed in 58 of 202 patients (28·7%, 95% CI 22·6-35·5) at day 42 and in 55 patients (27·2%, 21·2-33·9) at day 84. Successful global response with stable disease included in the de …

Infectious Diseases

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… Lyme erythema migrans), Treponema pallidum (chancre, secondary syphilis) rickettsial —Rocky Mountain spotted fever, ehrlichiosis, typhus viral exanthem —acute HIV, mononucleosis, rubella, measles, roseola, erythema infectiosum, chickenpox, shingles, coxsackie virus, echovirus fungal —Blastomyces, Coccidioides … Endemic fungal infections include Blastomyces dermatitidis (southeastern states, Manitoba, and Ontario), Coccidioides immitis (southwestern states), and Histoplasma capsulatum (Mississippi, Ohio River valleys, and Quebec) HISTORY —pattern and duration of fever, associated symptoms (cough, dyspnea, chest …

Critically Ill Immunosuppressed Host

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… The frequency of Cryptococcus, Histoplasma, Blastomyces, and Coccidioides organisms as causes of pneumonia depends on the geographic exposure of the patient. Among these mycoses, antigen detection techniques can be useful for finding Cryptococcus and Histoplasma organisms. … Table 54-6 Causes of Hypotension in Patients with HIV Infection Process Examples of Causes Distributive Shock Septic shock Bacterial Pneumococcus or Haemophilus organism pneumonia Vascular access infection Surgical wound Viral CMV, disseminated VZV Fungal Histoplasma, Coccidioides, Cryptococcus organisms …

Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumonia.

Pneumocystis pneumonia (PCP) is a fungal infection with primary occurrence in immunocompromised individuals by the etiologic agent Pneumocystis jirovecii. In those without previously identified risk factors, maintaining an index of suspicion for this diagnosis with search for underlying immunosuppressive cause is of utmost importance. Here, we present a case of fatal PCP in a patient without a known history of immunocompromise subsequently diagnosed with idiopathic CD4 lymphocytopenia (ICL) with an absolute CD4+ T-cell count of 7 cells/uL.

Совпадение в полном тексте источника
… Fungitell, QuantiFERON, Coccidioides, Histoplasma, and Blastomycosis were ordered and negative. An absolute CD4 + T-cell count was 7 cells/uL. Given his hypogammaglobulinemia and extremely low CD4 + T-cell count, one dose of intravenous immunoglobulin (IVIG) was administered. …

Atypical Calcitriol-Mediated Hypercalcemia in Late Life: A Hypothesis-Generating Case.

Calcitriol-mediated hypercalcemia is most commonly associated with granulomatous disease or lymphoma and rarely occurs without an identifiable cause. We present the case of a 96-year-old woman who developed severe symptomatic hypercalcemia with elevated 1,25-dihydroxyvitamin D (calcitriol), low 25-hydroxyvitamin D (calcidiol), suppressed parathyroid hormone, and no evidence of malignancy, granulomatous disease, endocrine dysfunction, or vitamin D intoxication. She improved with intravenous fluids, calcitonin, and corticosteroids. We hypothesize that age-related impairment of the fibroblast gro

Совпадение в полном тексте источника
… Investigation | Result | Normal Range Endemic mycoses Histoplasma yeast | <1:8 | <1:8 Histoplasma mycelia | <1:8 | <1:8 Coccidioides antibody | <1:2 | <1:2 Tuberculosis Quantiferon NIL (IU/mL) | 0.315 | Not applicable Quantiferon mitogen-NIL (IU/mL) | >10.000 | Not applicable Quantiferon TB1 antigen-NIL …

Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report.

BACKGROUND: Osteomyelitis caused by Aspergillus sp. is uncommon in dogs and cats and may occur in cases of disseminated aspergillosis, a rare and poorly described condition in veterinary medicine. CASE DESCRIPTION: Due to the scarcity of reports documenting this disease, particularly with localized involvement of the pelvic bones, the present case report aimed to describe the condition in an 8-year-old mixed-breed dog presenting with severe pain and lameness of the right pelvic limb. Radiographic examination revealed marked periosteal bone proliferation and osteolysis extending from the right

Совпадение в полном тексте источника
… The infecting fungal species vary according to geographic distribution ( Thrall, 2010 ; Schulz, 2013 ); however, Coccidioides immitis , Blastomyces dermatitidis , Histoplasma capsulatum , Cryptococcus neoformans , and Aspergillus spp. are the most frequently reported fungi in osteomyelitis cases ( Oxenford …

Clinical Manifestations of Human Exposure to Fungi.

Biological particles, along with inorganic gaseous and particulate pollutants, constitute an ever-present component of the atmosphere and surfaces. Among these particles are fungal species colonizing almost all ecosystems, including the human body. Although inoffensive to most people, fungi can be responsible for several health problems, such as allergic fungal diseases and fungal infections. Worldwide fungal disease incidence is increasing, with new emerging fungal diseases appearing yearly. Reasons for this increase are the expansion of life expectancy, the number of immunocompromised patien

Совпадение в полном тексте источника
… Coccidioidomycosis Coccidioidomycosis (also known as Valley Fever), caused by Coccidioides immitis and C. posadasii from soils, is a group of fungal infections of the Western hemisphere and is endemic to areas with reduced rainfall levels, occurring between the latitudes 40° north and 40° south [ 226 … Diagnosis includes detailed medical history, symptoms records, physical examinations, and lab tests (direct microscopy, histopathology, detection of Coccidioides antigens, molecular identification, culture from biopsy and blood) [ 228 , 229 ]. 4.3.6. …

Mycobiota и Antifungal Antibodies как новые целевые показатели для диагностики и прогнозирования болезней человека.

Человеческое тело колонизируется различными микроорганизмами, при этом наиболее активно изучаются бактерии. Однако грибы, которые в совокупности известны как «микобиота», все чаще признаются в качестве составных компонентов микробиоты, населяющей почти все мукосальные поверхности. Комменсальные грибы оказывают влияние на иммунитет хост-приемника, как и бактерии, и способствуют выполнению других важных функций, включая метаболизм. В этом новом понимании грибы рассматриваются как потенциальные биомаркеры для диагностики и прогнозирования различных заболеваний. В этом обзоре мы изучаем двойную ро

Совпадение в полном тексте источника
… These fungi, including genera like Coccidioides spp., Histoplasma spp., Paracoccidioides spp., and Blastomyces spp., possess the unique ability to switch between hyphal and yeast forms, a key factor in their pathogenicity. …

Late-occurring infections in a contemporary cohort of hematopoietic cell transplantation survivors.

BackgroundThere is a paucity of studies describing the incidence and risk factors for late-occurring (≥1 year) infectious complications in contemporary survivors of hematopoietic cell transplantation (HCT).MethodsThis was a retrospective cohort study of 641 1-year survivors of HCT, transplanted between 2010 and 2013 as adults, and in remission from their primary disease. Standardized definitions were used to characterize viral, fungal, and bacterial infections. Cumulative incidence of infections was calculated, with relapse/progression considered as a competing risk event. Fine-Gray subdistrib

Совпадение в полном тексте источника
… Mycoplasma , Propionibacterium , Proteus , Rhizobium , Rothia mucilaginosa , Salmonella , Enterobacter . b Adenovirus, Adenovirus, BK virus, Coronavirus, Epstein‐Barr virus, Human Papilloma virus, Herpes simplex virus, Human metapneumovirus, Norovirus, Hepatitis B, Enterovirus/Rhinovirus, Rotavirus. c Coccidioides …

9th Trends in Medical Mycology Held on 11-14 October 2019, Nice, France, Organized under the Auspices of EORTC-IDG and ECMM.

Dear Friends and Colleagues,It is a great honor and pleasure for us to invite you cordially to participate in the 9th Congress on Trends in Medical Mycology (TIMM-9) [...].

Neurology

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… Other infectious diseases of the spine are seen sporadically and agents include Cryptococcus , Toxoplasma, bacterial meningomyelitis, Coccidioides, Histoplasma, FIV, rabies, BDV, and others. …

Imaging of abdominal and pelvic infections in the cancer patient.

Infections are the most commonly encountered complications in patients with cancer. The classical signs and symptoms of infections are often not present in this patient population, which makes the diagnosis more challenging. Host factors play a major role in the development and prognosis of infections in cancer patients; these can be related to the underlying type of malignancy (solid organ versus hematological), tumor burden, anatomic obstruction, altered integrity of barriers (skin or mucosa), treatment-related factors (from chemotherapy, radiation treatment, surgery, interventional procedur

Совпадение в полном тексте источника
… Findings are consistent with infectious fungal peritonitis from coccidioides Fig. 20 Infectious peritonitis in a 64-year-old woman with gastric cancer and peritoneal carcinomatosis. …

Disorders of the Spinal Cord

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… Fungal causes include Cryptococcus neoformans , Blastomyces dermatitidis , Histoplasma capsulatum , and Coccidioides immitis . Pathophysiology FIP causes granulomatous inflammation of the meninges, ependymal cells, and choroid plexus. …

Manifestations of systemic disease in the retina and fundus of cats and dogs.

The fundus is unique in that it is the only part of the body that allows for a noninvasive and uninterrupted view of vasculature and nervous tissue. Utilization of this can be a powerful tool in uncovering salient incidental findings which point to underlying systemic diseases, and for monitoring response to therapy. Retinal venules and arterioles allow the clinician to assess changes in vascular color, diameter, outline, and tortuosity. The retina and optic nerve may exhibit changes associated with increased or decreased thickness, inflammatory infiltrates, hemorrhages, and detachments. While

Совпадение в полном тексте источника
… Like many other fungal infections Coccidioides spp. causes infection via inhalation followed by hematogenous dissemination to various organs. In dogs, coccidioidomycosis may cause ocular signs as the only manifestation of disease, and those can be either bilateral or unilateral ( 96 ). …

Pneumonia in Transplant Recipients: A Comprehensive Review of Diagnosis and Management.

Transplant recipients have an increased risk of complications, including graft dysfunction and infections, which can be life-threatening if not recognized early. Pneumonia ranks as one of the most frequent complications in both solid organ and hematopoietic stem cell transplants. Clinical symptoms manifest late during infections in immunocompromised patients. An aggressive approach centered on early confirmatory diagnosis and a low threshold for empiric therapy is often the most effective strategy. The isolation of a pathogen in an upper airway sample does not necessarily mean the same organis

Совпадение в полном тексте источника
… Geographic exposure can increase susceptibility to endemic fungal infections of Histoplasma (Ohio and Mississippi River valleys), Coccidioides (Southwest US), Paracoccidioides (Central and South America), Cryptococcus , and Blastomyces (Mid West, South-central, and Southeastern United States). …

Osteosarcoma of the appendicular skeleton in dogs: consensus and guidelines.

Osteosarcoma (OSA) in dogs poses a clinical challenge to veterinary practitioners across the globe. As knowledge evolves, so too do clinical practices. However, there remain uncertainties and controversies. There is value for the veterinary community at large in the generation of a contemporary wide-ranging guideline document. The aim of this project was therefore to assimilate the available published knowledge into a single accessible referenced resource and to provide expert clinical guidance to support professional colleagues as they navigate current OSA challenges and controversies. Primar

Совпадение в полном тексте источника
… Fungal osteomyelitis | Related to travel to endemic areas (e.g., Coccidioides , Blastomyces ). | Monostotic, metaphyseal lytic lesions; lung infiltrates possible. | Antifungal therapy; histologic and serologic confirmation required. …

Acute and Chronic Respiratory Failure in Cancer Patients

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… On the other hand, patients with T-cell defects are subject to infections with Cryptococcus, PJP, and endemic mycosis such as Coccidioides immitis, Blastomyces dermatitidis, and Histoplasma capsulatum . …

2020 ACVIM Forum On Demand Research Abstract Program.

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… Disease Suspected to be Associated with Parainfluenza Virus (ACVIM Resident Research Award eligible) ID21 | Anna Winner | The Role of Streptococcus equi Subspecies Zooepidemicus and Influenza Viruses in URIs in Shelter Cats ID22 | Krystle Reagan | Evaluation of the Clinical Performance of a Point‐of‐Care Coccidioides …