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Development of a composite trauma exposure risk index.

The high burden of exposure to chronic life adversities and trauma is quite prevalent, but assessment of this risk burden is uncommon in primary care settings. This calls for a brief, multiple dimensional mental health risk screening tool in primary care settings. We aimed to develop such a screening tool named the University of California, Los Angeles (UCLA) Life Adversities Screener (LADS). Using pooled data across 4 studies from the UCLA Center for Culture, Trauma, and Mental Health Disparities, 5 domains of mental health risk including perceived discrimination, sexual abuse histories, fami

Репродуктивная автономия женщин, живущих с множественной миеломой, участвующих в программе профилактики беременности.

Множественная миелома — неизлечимый гематологический рак, который в первую очередь затрагивает пожилых людей. Женщины, имеющие фертильный потенциал, составляют небольшую, но уникальную долю населения, страдающего от многочисленных миелом. Иммуноводные агенты (талидомид, линалидомид и помалидомид) являются высокоэффективными средствами лечения для улучшения длительных периодов глубокой ремиссии и долгосрочного выживания в Множестве миеломы, которые осуществляются в рамках программ контролируемого распределения, требующих наблюдения за беременностью для женщин с потенциалом деторождения, с тем ч

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… Reproductive justice in patient care: Tackling systemic racism and health inequities in sexual and reproductive health and rights in Canada. Reprod Health. 2022;19(1):1–8. 10.1186/s12978-022-01328-7. 19. Doyle L, McCabe C, Keogh B, Brady A, McCann M. … The politest form of racism: Sexual and reproductive health and rights paradigm in Canada. Reprod Health. 2021;18(1):1–5. 10.1186/s12978-021-01117-8. 22. Green J, Browne J. Principles of social research (J. Green, J. & Browne, Ed.). Open University Press. 2009. 23. …

Neural dynamics of pain expression processing: Alpha-band synchronization to same-race pain but desynchronization to other-race pain.

Both electroencephalography and functional magnetic resonance imaging studies have revealed enhanced neural responses to perceived pain in same-race than other-race individuals. However, it remains unclear how neural responses in the sensorimotor, cognitive, and affective subsystems vary dynamically in the first few hundreds of milliseconds to generate racial ingroup favoritism in empathy for pain. We recorded magnetoencephalography signals to pain and neutral expressions of Asian and white faces from Chinese adults during judgments of racial identity of each face. We found that pain compared

Measurement, Education and Tracking in Integrated Care (METRIC): use of a culturally adapted education tool versus standard education to increase engagement in depression treatment among Hispanic patients: study protocol for a randomized control trial.

BACKGROUND: Significant mental health disparities exist for Hispanic populations, especially with regard to depression treatment. Stigma and poor communication between patients and their providers result in low use of antidepressant medications and early treatment withdrawal. Cultural factors which influence treatment decisions among Hispanics include fears about the addictive and harmful properties of antidepressants, worries about taking too many pills, and the stigma attached to taking medications. Primary care settings often are the gateway to identifying undiagnosed or untreated mental he

Nondepressive Psychosocial Factors and CKD Outcomes in Black Americans.

BACKGROUND AND OBJECTIVES: Established risk factors for CKD do not fully account for risk of CKD in black Americans. We studied the association of nondepressive psychosocial factors with risk of CKD in the Jackson Heart Study. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We used principal component analysis to identify underlying constructs from 12 psychosocial baseline variables (perceived daily, lifetime, and burden of lifetime discrimination; stress; anger in; anger out; hostility; pessimism; John Henryism; spirituality; perceived social status; and social support). Using multivariable m

Mediators of racial and ethnic inequities in clinical trial participation among patients with cancer, 2011-2023.

BackgroundAlthough racially and ethnically minoritized populations are less likely to participate in cancer trials, it is unknown whether social determinants of health (SDOH) explain these inequities. Here we identify SDOH factors that contribute to racial and ethnic inequities in clinical trial participation among patients with 22 common cancers.MethodsThis retrospective cohort study used electronic health record data (2011-2023) linked to neighborhood (US Census tract) data from multiple sources. Patients were followed from diagnosis to clinical study drug receipt (proxy for trial participat

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… Institutional racism (or the role institutional systems have in race-based oppression, including racism within a specific institution) also influences inequities in trial participation ( 44 ). … Systemic and structural racism: definitions, examples, health damages, and approaches to dismantling. Health Aff (Millwood). 2022;41(2):171-178. doi: 10.1377/hlthaff.2021.01394 45. Mahal BA, Chen YW, Muralidhar V, et al. …

The Carceral Shadow: Criminal Justice as a Determinant of Health and Challenges for Policymakers.

UNLABELLED: Policy Points The criminal justice system functions as a primary social determinant of health in the United States, generating d … sing the lethal consequences of overcrowded facilities, inadequate health care access, and systemic racism embedded across criminal justice institutions. METHODS: This perspective piece synthesizes peer-reviewed literature, national surveillance data, and policy analyses to examine the criminal justice system as a social determinant of health. Drawing o …

Veterans Hospitals vs Non-Veterans Centers in the Prevention of Limb Loss.

IMPORTANCE: US veterans remain an at-risk population for limb loss, given the prevalent rates of coexisting diabetes and peripheral arterial … , and amputation (bearing in mind that race and ethnicity variables incompletely capture structural racism and systemic disparities in vascular disease). Race and ethnicity data are self-reported in the VA. Data were analyzed from May 2024 to January 2026. EXPOSURE: Prior minor (toe or forefoot) amputation. MAIN OUTCOME: Major (below-knee or above-knee …

Nurse workforce diversity and reduced risk of severe adverse maternal outcomes.

BACKGROUND: Racial and ethnic diversification of the physician and nurse workforce is recommended as a leverage point to address the impact of structural racism in maternal care, but empirical evidence supporting this recommendation is currently lacking. OBJECTIVE: This study aimed to assess the association between state-level registered nurse workforce racial and ethnic diversity and severe adverse maternal outcomes during childbirth. STUDY DESIGN: This population-based cross-sectional study analyzed 2017 US birth certificate data. Severe adverse maternal outcomes included eclampsia, blood …

Type I hybrid effectiveness-implementation randomised controlled trial to address intergenerational impact of war trauma and resilience among second-generation refugee children in the USA: Resettled Refugee Families for Healing (RRF4H) study protocol.

INTRODUCTION: Children from refugee families resettled in the USA face higher risks of serious mental health challenges compared with their native-born peers. Research shows that refugee youth in high-income countries frequently suffer from trauma-associated disorders such as post-traumatic stress disorder (PTSD), depression and anxiety. The high prevalence of trauma-associated mental health problems among these youth may be attributed to their own trauma exposure, especially if born in conflict zones, and post-resettlement challenges like poverty, acculturation difficulties, racism and discri…

Patient Sociodemographics and Comorbidities and Birth Hospital Characteristics Associated With Postpartum Emergency Department Care.

IMPORTANCE: Postpartum emergency department (ED) visits may indicate poor access to care and risk for maternal morbidity. OBJECTIVES: To id … ial and ethnic minority populations . These findings support the urgent need to mitigate structural racism underlying maternal health disparities.

Resuscitating Patient Rights during the Pandemic: COVID-19 and the Risk of Resurgent Paternalism.

The COVID-19 Pandemic a stress test for clinical medicine and medical ethics, with a confluence over questions of the proportionality of resuscitation. Drawing upon his experience as a clinical ethicist during the surge in New York City during the Spring of 2020, the author considers how attitudes regarding resuscitation have evolved since the inception of do-not-resuscitate (DNR) orders decades ago. Sharing a personal narrative about a DNR quandry he encountered as a medical intern, the author considers the balance of patient rights versus clinical discretion, warning about the risk of resurg

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… At this moment in our history, both in the United States and abroad, as we grapple with systemic racism and seek to give voice to those who have burdened under constraints that compromise their ability for self-advocacy we should think very carefully about the rights of patients. … Diagnosing and treating systemic racism. The New England Journal of Medicine. 2020. doi: https://doi.org/10.1056/NEJMe2021693 Robinson EM, Cadge W, Zollfrank A, Cremens MC, Courtwright AM. After the DNR: Surrogates who persist in requesting cardiopulmonary resuscitation. …

Расовые различия в миеломе и доступ к трансплантации стволовых клеток.

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

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… Wang J Vela MB Chin MH Addressing bias and racism against Asian American, Native Hawaiian, and Pacific Islander individuals: a call to action to advance health equity and leadership JAMA Netw Open 2023 6 e2325872 10.1001/jamanetworkopen.2023.25872 37494049 Wang J, Vela MB, Chin MH. … Addressing bias and racism against Asian American, Native Hawaiian, and Pacific Islander individuals: a call to action to advance health equity and leadership. JAMA Netw Open. 2023;6:e2325872. 37494049 10.1001/jamanetworkopen.2023.25872 14. …

Acceptance and Commitment to Empowerment Intervention to Reduce HIV Stigma and Promote Community Resilience: Protocol for an Implementation Study.

BACKGROUND: Racialized immigrants are disproportionately impacted by HIV in Canada. In 2022, 69.5% of first-time HIV cases, where race and/or ethnicity was reported, were among racialized individuals: Indigenous (22.6%), Black (18.0%), Asian and Arab (16.3%), and Latinx (10.1%). HIV vulnerability in racialized communities is reinforced by HIV stigma intersecting with prejudice and discrimination associated with racism, gendered oppression, homophobia, and economic marginalization. Stigma and discrimination impede public health efforts in HIV prevention, testing, treatment, and care. OBJECTIVE…

The gender dimensions of sexual violence against migrant domestic workers in post-2019 Lebanon.

INTRODUCTION: In December 2020, the Lebanese Parliament passed the landmark Law 205 against sexual harassment that could see perpetrators sp … reatment, fetishization, and violence each group of women faced. In addition to an overall sense of racism experienced by black MDWs, hierarchy within the MDWs' community presents itself in various forms-even at the early stages of recruitment at the agency. Undocumented MDWs are left powerless in terms of reporting sexual abuse and therefore, are at the …

Longitudinal effects of inpatient music therapy dosage on pain intensity and opioid utilization among patients with hematologic or oncologic conditions: a retrospective cohort study.

PurposeSeveral studies support the benefits of music therapy (MT) for improving symptoms within a single session among patients with hematologic/oncologic conditions, but none have examined real-world longitudinal impacts. This study evaluated whether there was a dose-response relationship between MT intervention exposure and longitudinal changes in pain intensity and opioid utilization.MethodsA retrospective electronic health record review was conducted of 283 hospital admissions among adult patients with hematologic/oncologic conditions who received MT and either reported pain ≥ 4/10 on the

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… .2022.11.004 36503109 PMC10079591 McGill LS, Hamilton KR, Letzen JE, Finan PH, Lanzkron SM, Smith MT, Haythornthwaite JA, Campbell CM (2022) Depressive and insomnia symptoms sequentially mediate the association between racism-based discrimination in healthcare settings and clinical pain among adults … Power-Hays A McGann PT When actions speak louder than words — racism and sickle cell disease N Engl J Med 2020 383 1902 1903 10.1056/NEJMp2022125 32871062 Power-Hays A, McGann PT (2020) When actions speak louder than words — racism and sickle cell disease. …

The American Society of Hematology Health Equity Compendium: examining health equity across the Blood journals.

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

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… Three discussed laboratory hematology, all on structural racism in neutrophil reference ranges. Twenty-one reviewed disease phenotype/presentation, treatment patterns, and/or outcome differences by patient demographics. … Structural racism is a mediator of disparities in acute myeloid leukemia outcomes. Blood. 2022;139(14):2212–2226. doi: 10.1182/blood.2021012830. 25. Kittai A, Huang Y, Bhat S, et al. Racial and socioeconomic disparities in CLL/SLL: analysis of SEER data from 2006 to 2019. …

Racial disparities in treatment patterns and clinical outcomes in patients with HER2-positive metastatic breast cancer.

Data characterizing demographics, treatment patterns, and clinical outcomes in black patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) are limited. registHER is a large, observational cohort study of patients (n = 1,001) with HER2-positive MBC diagnosed ≤6 months of enrollment and followed until death, disenrollment, or June 2009 (median follow-up of 27 months). Demographics, treatment patterns, and clinical outcomes were described for black (n = 126) and white patients (n = 793). Progression-free survival (PFS) following first-line therapy a

EQUITY-MS: оценка качества исследования и лечения множественной скlerозы на основе данных пяти специализированных нейрологических центров в Великобритании — протокол исследования.

ВВЕДЕНИЕ: Социальные определяющие факторы здоровья — это условия, в которых живут люди, и системы вокруг них, которые формируют эти условия. Социальные определяющие факторы здоровья могут влиять на диагностику и лечение людей с множественной склерозом (МС), даже в странах с универсальной системой здравоохранения. Это исследование будет изучать, влияет ли возраст, пол и/или пол, проживание в более социально-экономически уязвимой зоне и принадлежность к миноритарной этнической группе на доступ к диагностике МС и лекарствам, модифицирующим течение болезни (ДМТ) для людей, проживающих в районах об

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… Local area deprivation is a potential mediator of inequalities related to minoritised ethnicity, given that structural racism increases the chances that minoritised groups live in more deprived areas. … Our analysis assumes that there are common mechanisms across geographical areas through which personal characteristics affect healthcare access, including structural racism, sexism, classism and ageism. …

Тенденции смертности от почечной недостаточности среди многих пациентов в возрасте от миэломы ≥ 45 годы, 1999-2023Анализ данных ЦКЗ.

Множественная миелома (ММ) — плазменная порча клеток, которая часто осложняется почечным расстройством, что значительно ухудшает прогноз. Несмотря на то, что терапевтический прогресс улучшил выживание ММ, почечная недостаточность по-прежнему является одной из основных причин неблагоприятных последствий. В этом исследовании были рассмотрены долгосрочные тенденции и демографические различия в показателях смертности среди лиц, умерших в США, при этом ММ была названа основной причиной смерти и почечной недостаточности, которая была названа одной из причин смертности. Данные о смертности среди взро

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… Bailey ZD Structural racism and health inequities in the USA: Evidence and interventions Lancet 2017 389 10077 1453 1463 10.1016/S0140-6736(17)30569-X 28402827 Bailey, Z. D. et al. Structural racism and health inequities in the USA: Evidence and interventions. … Race, racism, and cardiovascular health: Applying a social determinants of health framework to racial/ethnic disparities in cardiovascular disease. Circ. Cardiovasc. Qual. Outcomes 15 (1), e007917 (2022). 35041484 10.1161/CIRCOUTCOMES.121.007917 35. …