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ESMO expert consensus statements on the screening and management of financial toxicity in patients with cancer.

BackgroundFinancial toxicity, defined as both the objective financial burden and subjective financial distress from a cancer diagnosis and its treatment, is a topic of interest in the assessment of the quality of life of patients with cancer and their families. Current evidence implicates financial toxicity in psychosocial, economic and other harms, leading to suboptimal cancer outcomes along the entire trajectory of diagnosis, treatment, supportive care, survivorship and palliation. This paper presents the results of a virtual consensus, based on the evidence base to date, on the screening an

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… The extent to which employer or social welfare mitigation strategies (such as paid sick leave) may alleviate this has rarely been investigated. … The extent to which employer or social welfare mitigation strategies (such as paid sick leave) may alleviate this has rarely been investigated. …

Effectiveness of bilingual health education on obesity and dietary behaviors in Mongolian adolescents: a six-month intervention study.

BackgroundObesity among adolescents has become a global public health concern. Previous studies have shown that multidimensional interventions, such as school-based programs, health education, and guidance on diet and physical activity, effectively improve obesity in adolescents. However, there is a lack of research on bilingual health education interventions in minority language environments in rural and pastoral areas of China. Based on a 2023 field survey of students from three Mongolian middle schools in Ar Horqin Banner, Chifeng City, Inner Mongolia, this study evaluated the effect of a 6

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… However, during the follow-up intervention period, several participants were lost to follow-up due to sick leave, competition participation, refusal to provide biological samples, and other reasons. …

Пациентский опыт Myelin Oligodendrocyte Glycoprotein Antibody-Associated Beacy: качественные пациенты и клинические интервью, информирующие о разработке концептуальной модели.

ВВЕДЕНИЕ: Миелин олигодендроцит гликпротеин, связанный с антителами (МОГАД), представляет собой редкое аутоиммунное заболевание центральной нервной системы. В настоящее время мало что известно о признаках, симптомах и связанных со здоровьем аспектах воздействия MOGAD с точки зрения пациента. В ходе этого исследования был изучен опыт пациентов MOGAD с помощью концептуальных опросов пациентов с MOGAD и врачами в целях разработки концептуальной модели MOGAD. МЕТОДЫ: На основе обзора опубликованной литературы была разработана предварительная концептуальная модель знаков MOGAD, симптомов, методов л

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… Additionally, a study in patients with NMOSD ( n  = 166) and MOGAD ( n  = 46) reported that 60% of patients were unemployed, and among those who work, many reduced their hours or take sick leave, which often affects salary [ 50 ]. …

Patient-Centered Insights on Treatment Decision Making and Living with Acute Myeloid Leukemia and Other Hematologic Cancers.

Expectations relating to treatment and survival, and factors influencing treatment decisions are not well understood in adult patients with acute myeloid leukemia. This study analyzed combined findings from a targeted literature review with patient-reported information shared on YouTube to further understand patient perspectives in hematologic cancers and, in particular, acute myeloid leukemia. The targeted literature review included articles concerning patient (aged ≥ 18 years) experiences or perspectives in acute myeloid leukemia or other hematologic cancers. YouTube video selection criteria

Fear of cancer recurrence in patients with multiple myeloma: Prevalence and predictors based on a family model analysis.

ObjectiveFear of cancer recurrence (FCR) is a common psychosocial sequela among cancer survivors, but data on patients with multiple myeloma are scarce. This study calculated the prevalence of FCR and identified family and social factors that predict FCR in the study population.MethodsWe recruited 127 myeloma patients and their partners to participate in a cross-sectional survey from a regional tertiary cancer centre in China. The questionnaires included items on demographic characteristics and from the fear of disease progression simplified scale, family hardiness index and Social Support Sca

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… The majority (87.2%, n = 111) of the patients were retired or on sick leave, and 93.7% declared no religion. The ages of the 127 corresponding partners ranged from 27 to 80 years, with a mean age of 57.71 years (SD = 9.96). Of the partners, 12.6% ( n = 16) had graduated from college or above. … leave | 111 | 35.57 ± 11.01 | ‐ | ‐ Occupation | | | 1.918 | 0.13 Office clerk/worker | 59 | 35.49 ± 10.54 | ‐ | ‐ Agricultural worker | 51 | 34.67 ± 10.42 | ‐ | ‐ Self‐employed | 7 | 27.14 ± 16.17 | ‐ | ‐ Freelance | 10 | 39.90 ± 12.23 | ‐ | ‐ Time since diagnosis (years) | | | 3.262 | 0.024 <1 …

Cancer treatment-related financial toxicity in Japan: a scoping review.

Financial toxicity during cancer survival has been studied mainly in the United States; 47-49% of cancer survivors reported financial hardships and 12-63% reported debt owing to treatment costs. Financial toxicity is influenced by each country's economic status and healthcare system. We aimed to review the evidence on financial toxicity in Japan. A systematic search was performed using PubMed and Ichushi databases. We included English or Japanese peer-reviewed articles that (1) explored the experiences of cancer patients facing financial toxicity due to cancer diagnosis and treatment, (2) were

Reimbursement of licensed cell and gene therapies across the major European healthcare markets.

ObjectiveThe aim of this research is to identify the pricing, reimbursement, and market access (P&R&MA) considerations most relevant to advanced therapy medicinal products (ATMPs) in the Big5EU, and to inform their manufacturers about the key drivers for securing adoption at a commercially viable reimbursed price.MethodologyThe research was structured following three main steps: 1) Identifying the market access pathways relevant to ATMPs through secondary research; 2) Validating the secondary research findings and addressing any data gaps in primary research, by qualitative interviews with nat

Using virtual reality hypnosis during stem cell transplant for patients in hematology: A protocol for a feasibility randomized study.

BackgroundStem cell transplantation is a highly stressful treatment for hematological cancer patients, negatively impacting their quality of life. Hypnosis has proven effective in managing symptoms like pain, fatigue, and anxiety, and improving quality of life. Virtual reality (VR) is used in cancer treatments to distract from pain, and combining VR with hypnosis (VRH) could enhance the hypnotic experience. However, methodological limitations in current studies prevent clear evaluation of its effectiveness, particularly for individualized care and psychosocial interventions.Aims1) To evaluate

HERV Dys Regulation в деле Myalgic Encephalomyelitis и Multic Sclerosis Responsive to Rituximab.

В этой статье резюмируется случай, когда 30-летний мужчина диагностировал синдром мальгического энцефаломелита/хронического утомительного синдрома (ME/CFS) и его продольный слежение, в результате чего через восемь лет был диагностирован множественный склероз (MS). Наиболее ощутимым результатом стала его реакция на ритуксимаб после систематического отказа в предварительном лечении. Хотя выражение эндогенных ретровирусных белков ассоциируется с автоиммунитетом, пациент не продемонстрировал более широкое выражение токсичного белка HERV (человеческий ретровирус)-W ENV, который является целью текущ

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… This resulted in prolonged sick leaves, with the patient living mostly confined to bed. Further evaluations ruled out autoimmune, thyroid, myasthenia, endocrine, vitamin deficiency, and infectious pathologies, except for EBV IgG positivity in 2015, at age 25. …

Health and economic impact of caregiving on informal caregivers of people with chronic diseases in sub-Saharan Africa: A systematic review.

With a disproportionate burden of chronic diseases and severe shortage of health workers in sub-Saharan Africa, the region implicitly relies on informal caregivers (ICGs) to support the patients both within and outside the health facilities. The aim of this review is to systematically summarise evidence on the health and economic impact of caregiving on informal caregivers of patients with chronic diseases in sub-Saharan Africa. Medline (Ovid), CINAHL (EBSCOhost), PsycINFO (Ovid), Embase (Ovid), Global Health, and Web of Science databases were systematically searched to identify original artic

Depressive and anxiety symptoms among Japanese cancer survivors: Japan cancer survivorship research project.

BackgroundThis study aimed to clarify predictors of depressive symptoms and anxiety symptoms after cancer diagnosis among Japanese cancer survivors (CSs).MethodsAs part of a Japanese cancer survivorship research project commissioned by the Ministry of Health, Labour and Welfare (MHLW) of Japan, we conducted a web-based nationwide survey of CSs in 2018. We analyzed the risk factors for depressive and anxiety symptoms, as measured by the Hospital Anxiety and Depression Scale Japanese version (HADS).ResultsOf 1,234 Japanese CSs, mean score of HADS-depression and HADS-anxiety were 4.08 and 4.78, r

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… Predictors of resignation and sick leave after cancer diagnosis among Japanese breast cancer survivors: a cross-sectional study. BMC Public Health. 2021;21(1):138. doi: 10.1186/s12889-021-10168-2. 11. Kugaya A, Akechi T, Okuyama T, Okamura H, Uchitomi Y. … Returning to work after sick leave due to cancer: a 365-day cohort study of Japanese cancer survivors. J Cancer Surviv. 2016;10(2):320–329. doi: 10.1007/s11764-015-0478-3. 19. Wada S, Shimizu K, Inoguchi H, Shimoda H, Yoshiuchi K, Akechi T, Uchida M, Ogawa A, Fujisawa D, Inoue S, et al. …

Perceptions and Experiences of Hematopoietic Cell Transplantation Patients During the COVID-19 Pandemic.

ObjectivesSince March 2020, the severe acute respiratory syndrome coronavirus-2 pandemic has affected the global community, but poses unique challenges for individuals with cancer. Patients diagnosed with hematologic malignancies undergo aggressive therapies followed by hematopoietic cell transplantation (HCT) as a potential curative treatment. HCT recipients can be immunocompromised for extended periods of time, and even pre-pandemic, transplant patients reported depression and anxiety due to restrictions and infection prevention measures they had to adhere to as part of transplant precaution

Physical therapy for multiple myeloma patients with severely hindered daily living activities due to bone lesions: a report of two cases.

[Purpose] Physical therapy for patients with multiple myeloma requires appropriate exercise intensity and risk management due to osteolytic lesions. However, the optimal strategy for setting exercise intensity remains unclear. We report cases in which physical therapy was performed using the Borg scale and the Common Terminology Criteria for Adverse Events v4.0 as indicators of improvement in the performance of activities of daily living without causing adverse events. [Participants and Methods] Two patients with multiple myeloma, whose performance status was 4, underwent resistance training o

Прогнозирующие факторы развития инвалидности в множестве склерозов в реальной жизни: определение FSEP-высокой категории (OFSEP-HD) во Франции.

ЦЕЛЬ: Определение прогнозируемых факторов инвалидности при множественном склерозе (МС), т.е.1) выявлять факторы, определяющие динамику развития инвалидности;2) изучение эффективности методов лечения с целью видоизменения заболеваний (ДМТ);3) объединить детерминанты и ДРТ для создания ориентированных на пациента средств прогнозирования и ()4) проводить экономический анализ. УЧАСТНИКИ: Лица, зарегистрированные во Французской базе данных Французской обсерватории по склерозам в плаке (OFSEP), были включены в эту группу лиц с высоким определением FOSEP, если они имели диагноз MS, ≥15 :: возраст и у

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… Third, the OFSEP-HD cohort will be linked to the French Système national des données de santé (SNDS) claims database registering all data for reimbursed health prescriptions and hospital stays covered by the national health insurance system. 2 32 Sick leave and disability status/pension will be obtained … These health states are associated with utility weights that can be used in an econometric approach. 40 41 Social consequences assessed by employment situation, sick leave occurrence and duration, unemployment or dependency. …

Сочетание виртуальной реальности и гипноза? Исследование опыта работы с пациентами с множественной миеломой после трансплантации стволовых клеток.

Множественная миелома (ММ) и трансплантация стволовых клеток (ЦТ) оказывают значительное влияние на качество жизни пациентов. Виртуальная реальность с гипнозом (ОВГ) стала многообещающим нефармакологическим вмешательством для решения этих проблем, однако данных о ее приемлемости и опыте пользователей по-прежнему недостаточно. В ходе этого исследования была проведена оценка приемлемости и опыта использования ОВЗ среди взрослых пациентов с МИ, прошедших аллогенный СХТ. Участники использовали прикладную программу VRH и оценили свой опыт с помощью стандартизированных вопросников и полуструктуриров

Ambulatory care after acute kidney injury: an opportunity to improve patient outcomes.

Purpose of reviewAcute kidney injury (AKI) is an increasingly common problem among hospitalized patients. Patients who survive an AKI-associated hospitalization are at higher risk of de novo and worsening chronic kidney disease, end-stage kidney disease, cardiovascular disease, and death. For hospitalized patients with dialysis-requiring AKI, outpatient follow-up with a nephrologist within 90 days of hospital discharge has been associated with enhanced survival. However, most patients who survive an AKI episode do not receive any follow-up nephrology care. This narrative review describes the e

Экспериментальное технико-экономическое обоснование исследования виртуальной оценки гейт на основе реальности с орехами у людей с множественным склерозом: исследовательский протокол.

Множественный склероз (МС) часто приводит к значительным нарушениям в походах и мобильности. Несмотря на то, что пешие брекеты обычно предписываются, их эффективность в реальном мире ограничивается недостаточной адаптацией. Традиционные клинические оценки основываются на субъективных масштабах и могут не в полной мере отражать проблемы повседневной жизни. Неизмеримая виртуальная реальность (VR) и износимые сенсоры предлагают перспективные решения для экологического мониторинга, однако их комбинированное использование по-прежнему не является приемлемым для ортопедической поддержки в MS. В рамка

Проверка диагноза множественных склерозов в шведском национальном регистре пациентов.

В эпидемиологических исследованиях широко используются реестры населения. Мы стремились оценить обоснованность множественных склерозовых (MS) диагнозов, зарегистрированных в шведском национальном регистре пациентов (НСП), с помощью two последовательные алгоритмы определения дел на основе регистров. Психиатрические пациенты в возрасте до одного года 16-64 :: были определены годы, полученные в ходе проведения и специализированного амбулаторного обследования 2001-2013, с использованием кода G35 Международной классификации болезней. Эти выявленные диагнозы MS были подтверждены с помощью two послед

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… Longitudinal integration database for sick leave and labour market studies (LISA) 1990–2013. (Longitudinell integrationsdatabas för sjukförsäkrings- och arbetsmarknadsstudier (LISA) 1990–2013 (in Swedish) ). Örebro: Statistics Sweden (Statistika centralbyrån); 2016. 29. …

Managing Matajoosh: determinants of first Nations' cancer care decisions.

BackgroundAccessing cancer treatment requires First Nation peoples living in rural and remote communities to either commute to care, or to relocate to an urban centre for the length or part of the treatment. While Canadians living in rural and remote communities must often make difficult decisions following a cancer diagnosis, such decisions are further complicated by the unique policy and socio-historical contexts affecting many First Nation peoples in Canada. These contexts often intersect with negative healthcare experiences which can be related to jurisdictional confusion encountered when

"Anecdotal evidence": why narratives matter to medical practice.

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