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Rehabilitation and acute exacerbations.

Recent evidence indicates that acute exacerbations of chronic obstructive pulmonary disease aggravate the extrapulmonary consequences of the disease. Skeletal muscle dysfunction, a sustained decrease in exercise tolerance, enhanced symptoms of depression and fatigue are reported. Avoidance of physical activities is likely to be a key underlying mechanism and increases the risk of new exacerbations. Pulmonary rehabilitation is an intervention targeting these systemic consequences. Exercise strategies need to be adapted to the increased feelings of dyspnoea and fatigue. This review aims to descr

Myositis unrelated to the inoculation site after COVID-19 vaccination: a case report.

We describe the case of a 49-year-old right hand-dominant woman with myositis of the biceps brachii muscle unrelated to the inoculation site following Pfizer-BioNTech COVID-19 vaccination on the deltoid muscle of the left shoulder. Coronavirus disease 2019 (COVID-19) pandemic has involved global spread, and different vaccines including inactivated, protein, vectored, and nucleic acid vaccines have been developed and administered. Common side effects of COVID-19 vaccines include general manifestations such as headache, fever, and fatigue, and various musculoskeletal symptoms. Here, we present a

Effects of Transcranial Stimulation on Resistance Exercise in Mentally Fatigued Subjects.

The objective was to analyze the effect of anodic transcranial direct current stimulation over the the primary motor cortex (M1) on resistance exercise in mentally fatigued individuals. Thirty-five participants performed a Stroop task to induce mental fatigue until they reached 50 mm on the visual analogue scale under three different conditions in a randomized, double-blind, crossover experimental trial. The participants completed a resistance training session with six sets for muscle failure with fixed load (Vload=1 ms-1) after the Stroop task. During the resistance training session, performa

Changes in countermovement jump performance and subjective readiness-to-train scores following a simulated soccer match.

The study investigated whether countermovement jump (CMJ) metrics and subjective responses to a readiness-to-train questionnaire (RTT-Q) tracked simulated match-induced acute fatigue. This was a randomized cross-over repeated measures study. Participants were assigned into one of two groups; CONTROL or LIST. The LIST group performed the Loughborough Intermittent Shuttle Run (LIST), which was designed to simulate the demands of a soccer match. The CONTROL performed light physical activity at an intensity of <65% of maximal heart rate. Each group performed three CMJ's and completed an RTT-Q befo

Muscle strain injury: diagnosis and treatment.

Muscle strain is a very common injury. Muscles that are frequently involved cross two joints, act mainly in an eccentric fashion, and contain a high percentage of fast-twitch fibers. Muscle strain usually causes acute pain and occurs during strenuous activity. In most cases, the diagnosis can be made on the basis of the history and physical examination. Magnetic resonance imaging is recommended only when radiologic evaluation is necessary for diagnosis. Initial treatment consists of rest, ice, compression, and nonsteroidal anti-inflammatory drug therapy. As pain and swelling subside, physical

Роль VibraPlus в утомлении пациентов с множественным склерозом: случайный контролируемый процесс.

Предыстория и цель: Усталость представляет собой отличительный симптом множественного склероза (MS), однако его диагностика и клиническая оценка сопряжены с трудностями, поскольку он описывается как субъективное чувство истощенного физического и психического ощущения. Исследования также показали, что подходы, основанные на терапии и робототехнике, а также использование вибрации, которые используются для улучшения сенсорной интеграции, уменьшают усталость. Основным результатом этого исследования является оценка воздействия применения вибрации с помощью фокуса на снижение усталости, мышечной сил

Совпадение в полном тексте источника
… Resistance training activity based on muscle-strengthening exercises was performed 2 times a week for 45 min each session to increase resistance to muscle fatigue and improve functional endurance. …

Differential responses of spinal motoneurons to fatigue induced by short-lasting repetitive and isometric tasks.

Compared to isometric activities, the neural basis of fatigue induced by repetitive tasks has been scarcely studied. Recently, we showed that during short-lasting repetitive tasks at the maximal possible rate (finger tapping for 10 and 30s), tapping rate and maximal voluntary contraction (MVC) force decrease at the end of finger tapping. We also observed larger silent periods (SP) induced by transcranial magnetic stimulation during MVC post finger tapping. However, if SP were induced by cervicomedullary stimulation (CMS) they remained unchanged. This suggested a supraspinal origin of fatigue f

Mouse models of myasthenia gravis.

Myasthenia gravis is a muscle weakness disease characterized by autoantibodies that target components of the neuromuscular junction, impairing synaptic transmission. The most common form of myasthenia gravis involves antibodies that bind the nicotinic acetylcholine receptors in the postsynaptic membrane. Many of the remaining cases are due to antibodies against muscle specific tyrosine kinase (MuSK). Recently, autoantibodies against LRP4 (another component of the MuSK signaling complex in the postsynaptic membrane) were identified as the likely cause of myasthenia gravis in some patients. Fati

Reduced maximum shortening velocity in the absence of phosphocreatine observed in intact fibres of Xenopus skeletal muscle.

1. ADP inhibits the maximum shortening velocity (V0) in skeletal muscle. [ADP] may increase considerably during contractions and reduce V0 in the absence of energy buffering by phosphocreatine (PCr). We have tested this hypothesis by comparing V0 in long and short tetani produced in situations where PCr buffering is absent. 2. Single, intact muscle fibres were dissected from toe muscles of Xenopus and stimulated by current pulses at 20 degrees C. The test sequence consisted of a 400 ms tetanus, followed after 3 s by a 1400 ms tetanus and after an additional 4 s by a 400 ms tetanus. V0 was meas

Mechanical work derived using markerless motion capture provides a valid indication of acute neuromuscular fatigue in tennis.

Whilst workload monitoring is key to managing performance and injury risk, effective strategies in tennis are not well-established. Mechanical work (external and internal components), measurable through markerless motion capture approaches, provides a novel way to quantify workload. To determine the suitability of this approach, this study investigated the association between mechanical work and acute neuromuscular fatigue. Fifteen tennis players completed a tennis-specific on-court fatiguing protocol interspersed with sprint tests. Peak sprint velocity (measure of acute neuromuscular fatigue)

Physiological limb tremor modulation by physical exertion: a systematic review and meta-analysis in healthy adults.

INTRODUCTION OR BACKGROUND: Physiological tremor is a low-amplitude, high-frequency oscillation of body segments influenced by both mechanical and neurogenic factors. Its modulation by physical exertion has emerged as a potential indicator of neuromuscular fatigue in healthy individuals. SOURCES OF DATA: We conducted a systematic search across four databases (PubMed, Scopus, Web of Science, and SPORTDiscus) in accordance with PRISMA 2020 guidelines. Twenty-eight experimental studies involving healthy adults and reporting tremor outcomes post-exertion were included. AREAS OF AGREEMENT: The ma

Fatigue-induced Landing Alterations in ACL Reconstructed Athletes after Return-to-Sport.

At the time of return-to-sport, anterior cruciate ligament reconstructed athletes still show altered neuromechanics in their injured leg during single leg hopping tasks. Part of these alterations can be magnified when these athletes are fatigued. So far, little is known whether fatigue-induced landing alterations persist after return-to-sport. Therefore, the aim of this study was to evaluate whether these alterations persist in the six months following return-to-sport. Sixteen anterior cruciate ligament reconstructed athletes performed five unilateral hop tasks before and after a fatigue proto

Vaginal Lubrication and Pressure Increase Induced by Pudendal Nerve Stimulation in Cats.

BACKGROUND: Vaginal lubrication and contractions are among the top difficulties affecting sexual intercourse in women after spinal cord injury. AIM: This study aimed at determining if pudendal nerve stimulation (PNS) can improve vaginal lubrication and induce increases in vaginal pressure. METHODS: In anesthetized cats, a small piece of cotton was inserted into the vagina for 10 minutes with or without PNS to measure vaginal wetness by the weight increase of the vaginal cotton. Then, a small balloon catheter was inserted into the vagina to measure the pressure increase induced by PNS. Intens

Hyperbaric oxygenation and blood lactate clearance: study in sixty male naval cadets.

The research was aimed to study the effects of a 30 minute exposure to 2.5 ATA with 100% O2-inhalation on lactate concentration after muscular fatigue from incremental exercise on a cycle ergometer The subjects were 60 male naval cadets aged 20-23 years whose physical fitness was equivalent to the average athletes. All volunteers participated in the first VO2 max exercise test to obtain their baseline data and randomly assigned into 3 groups of 20. The 3 groups were: Rest recovery group (RR), Oxygen recovery group (OR), and the Hyperbaric oxygenation (HBO2) recovery group (HR). The volunteers

Spasticity, ataxia and fatigue in multiple sclerosis.

Multiple sclerosis frequently results in a wide range of symptoms which often coexist, creating a complex pattern of disability. Chief among these symptoms, both in relation to their frequency and their impact on the patient, are spasticity, ataxia and fatigue. This chapter discusses the pathological basis and current treatment of these symptoms and stresses the importance of a multidisciplinary approach to their management, producing a comprehensive care plan which incorporates these and any other coexisting problems.

RACLET: the Ramp Above Critical Level Endurance Test to evaluate critical velocity in running.

Critical velocity ([Formula: see text]) is an important fatigability threshold in running, but only strenuous methods exist to assess it (e.g. time-trials). Based on a novel mathematical model of fatigability, the Ramp Above Critical Level Endurance Test (RACLET), a simple 5-min test to evaluate [Formula: see text] was developed. This study aimed to test the measurement properties of this novel non-exhaustive test. Thirty-eight participants performed two RACLET (session 1) and three time-trials (sessions 2-4). For the RACLET, velocity target tracking was guaranteed by either a pacing bike or c

The Effect of Mental and Muscular Fatigue on the Accuracy and Kinematics of Dart Throwing.

In this study, we analyzed the effect of mental and muscular fatigue on the accuracy and kinematics of dart throwing. For this purpose, 28 young adults (19 females and 9 males) aged 25-35 years, without any regular experience in dart throwing, participated in this study. We evaluated their dart throwing skills in mental fatigue, muscular fatigue, and non-fatigue conditions. To induce mental fatigue, we used the Stroop task for 70 minutes and a simulated dart throwing exercise with an elastic band. In all three conditions, we collected accuracy data, based on the score of the dart on the board

Trunk variability and local dynamic stability during gait after generalized fatigue induced by incremental exercise test in young women in different phases of the menstrual cycle.

PURPOSE: The purpose of this study was to identify how generalized fatigue along with hormonal changes throughout the menstrual cycle affects trunk variability and local dynamic stability during gait. METHODS: General fatigue was induced by an incremental test on a treadmill, and the menstrual cycle was divided into three phases: follicular, ovulatory, and luteal. Twenty-six healthy, young volunteers (aged 18 to 28 years) who did not use oral contraceptives or other hormonal drugs with a regular menstrual cycle participated in the study. They walked on the treadmill for 4 min at the preferred