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Prognostic value of D3 lymph node dissection and nutritional status in colorectal cancer patients aged 80 years and older.

PURPOSE: To evaluate the impact of D3 lymph node dissection and nutritional status on outcomes in patients aged ≥80 years with colorectal cancer. METHODS: We retrospectively analyzed patients aged ≥80 years who underwent curative resection for stage I-III colorectal cancer between April 2007 and February 2020. Patients were divided into D3 and non-D3 lymph node dissection groups. Propensity score matching was performed to reduce baseline differences. Short- and long-term outcomes, including overall survival (OS), disease-free survival (DFS), and cancer-specific survival (CSS), were compared. …

Investigating Handgrip Strength as a Practical Biomarker for Therapeutic Endpoints and Nutritional Status in Patients with Inflammatory Bowel Disease.

PURPOSE: Current biomarkers for inflammatory bowel disease (IBD) often rely on invasive procedures and lack broad availability, limiting their utility in clinical practice. This study aims to investigate the association between handgrip strength (HGS) and crucial treatment endpoints in IBD, such as disease activity, endoscopic severity and nutritional status in patients with IBD. METHODS: This double-center study enrolled patients with Crohn's disease (CD) and ulcerative colitis (UC). The disease activity, endoscopic severity, health-related quality of life (HRQoL) and presence of depressive …

Nutritional Status, Dietary Practices, and the Double Burden of Malnutrition Among School-Aged Children in Cameroon: A Systematic Review.

Undernutrition remains highly prevalent among children and adolescents in Cameroon, while increasing rates of overweight and obesity reflect an ongoing nutrition transition and a growing double burden of disease. This systematic review aimed to provide a comprehensive overview of research conducted on nutritional status, dietary intake, and nutrition-related practices in nursery, primary, and secondary schools in Cameroon. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Four electronic databases (PubMed, Sc…

Nutritional status among North Korean refugee and immigrant children in South Korea: evidence of a double burden of malnutrition.

OBJECTIVES: Children from migrant and refugee families may face a double burden of malnutrition, with undernutrition and obesity occurring within the same population. However, evidence on the nutritional status of North Korean refugee (NKR) and immigrant children in South Korea (SK) remains limited. This study compared nutritional status among SK, NKR, and immigrant children. METHODS: Data for 2,856 SK children were obtained from the 2021-2023 Korea National Health and Nutrition Examination Survey. Separately, 336 NKR children and 597 immigrant children were recruited between 2021 and 2025. N…

Nutritional status impact on engraftment time in hematopoietic stem cell transplants (HSCT) in Semarang, Indonesia: A cross-sectional study.

BackgroundNutritional support is a critical consideration in the care of individuals undergoing hematopoietic stem cell transplantation (HSCT), given the metabolic alterations induced by intensive treatments. This study aimed to explore the correlation between nutritional status and the time to engraftment in HSCT patients at Dr. Kariadi General Hospital, Semarang, Indonesia.MethodsThis study included adult patients with malignant diseases who underwent autologous or allogeneic HSCT at Dr. Kariadi General Hospital between 2013 and 2023. Nutritional status was evaluated using body mass index (B…

Dietary intake patterns and nutritional adequacy in older adults with predialysis chronic kidney disease: a comparison by diabetes status.

OBJECTIVE: Nutritional management is essential in caring for patients with chronic kidney disease (CKD), older adults at higher risk of malnutrition and comorbidities. However, data on actual dietary intake patterns in older adults with predialysis CKD, especially by diabetes mellitus (DM) status, remain limited. METHODS: This cross-sectional study included 106 patients aged ≥65 years with CKD stage G3a or higher, divided into DM (n=67) and non-DM (n=39) groups. Dietary intake was assessed using a single 24-hour recall. Nutrient and food-group intakes were compared with recommended levels. R

Состояние питания, способность к антиоксидантам в рационе питания и разнообразие рациона питания у пациентов с недавно диагностированными гематологическими отклонениями: тематическое исследование.

ППОЗ: Состояние питания и способность к антиоксидантам в рационе питания являются важными факторами, определяющими клиническую устойчивость к раку; однако данные о гематологических заболеваниях по-прежнему ограничены. Мы поставили перед собой цель сравнить состояние питания, общий потенциал рациона питания с антиоксидантами (DTAC) и разнообразие рациона питания между пациентами с недавно диагностированными гематологическими отклонениями и здоровыми средствами контроля. МЕТОДЫ: Это тематическое исследование включало 34 больные с недавно диагностированными гематологическими заболеваниями12 лимфо

Совпадение в аннотации оригинала
PURPOSE: Nutritional status and dietary antioxidant capacity are important determinants of clinical resilience in cancer; however, data in hematological malignancies remain limited. We aimed to compare nutritional status, dietary total antioxidant capacity (DTAC), and dietary diversity between patients with newly diagnosed hematological malignancies and heal…

Zinc as a Biomarker of Nutritional Status and Clinical Burden in Recessive Dystrophic Epidermolysis Bullosa: Implications for Preventive Monitoring.

Background/Objectives: Recessive dystrophic epidermolysis bullosa (RDEB) is a severe congenital genodermatosis characterized by skin and muc … kin involvement. Conclusions: These findings identify serum zinc as a clinically relevant marker of nutritional status and complication burden in RDEB. While no causal or therapeutic effects can be inferred from this cross-sectional study, the strong and biologically plausible associations observed suggest a rationale for systematic monitoring and correction of zinc …

Assessing the nutritional status and micronutrient gaps in Sierra Leone: a systematic rapid review of women, children, and adolescents.

BACKGROUND: Sierra Leone continues to experience a substantial burden of malnutrition across all age groups. In response, the government has implemented several nutrition strategies, including the 2017-2021 RMNCAH&N Strategy and routine vitamin A supplementation, among others. While national surveys and programme evaluations have provided valuable insights, evidence on micronutrient status and dietary intake among women, children, and adolescents remains fragmented, limited, and in some cases outdated. This systematic rapid review aimed to synthesise existing data, map nutritional outcomes, id

Splenic flexure colon cancer may represent a distinct prognostic subtype associated with elevated systemic inflammation and impaired nutritional status.

BACKGROUND: Splenic flexure colon cancer (SFCC) is a rare gastrointestinal malignancy distinguished by its unique anatomical location and dual vascular supply. Nevertheless, its clinical behavior, prognostic outcomes, and underlying risk factors remain inadequately defined. METHODS: A two-cohort study design enrolled 478 patients with stage II-III colon cancer. A colon cancer cohort (2012-2017) compared survival outcomes across tumor locations, while a separate SFCC-specific cohort (2012-2022) evaluated prognostic biomarkers in SFCC patients. A composite nutrition-inflammation integrating ind

Association of Dysphagia Severity with Nutritional Status and Muscle Function in Outpatients with Multiple Sclerosis: A Cross-Sectional Study.

Background/Objectives: Dysphagia may adversely affect nutritional status in patients with Multiple Sclerosis (MS). This study aimed to investigate the associations between dysphagia severity and (i) nutritional status, assessed by the Malnutrition Universal Screening Tool (MUST) and Global Leadership Initiative on Malnutrition (GLIM) criteria, and (ii) secondary sarcopenia indicators according to the European Working Group on Sarcopenia in Older People-2 (EWGSOP2) framework. Materials and Methods: This cross-sectional study enrolled 32 consecutive adult outpatients with confirmed MS and self-r…

Evaluation of quality of life, sleep quality, depression, and nutritional status in community living older adults using videoconference method.

The aim of this study was to evaluate quality of life, sleep quality, depression level, and nutritional status in older adults using a videoconference-based method, and to examine the effects of these variables on quality of life through a multiple linear regression model. Eighty-four older adults aged 65 to 75 with a mean age of 69.85 ± 2.34 participated in the study. Evaluations of older adults were made using the videoconference method via smartphone. Quality of life of older adults was assessed with the Nottingham Health Profile, sleep quality with the Pittsburgh Sleep Quality Index, depre…

Nutritional Status and Its Determinants among Adults with Cancer Prior to the Initiation of Chemotherapy: An Ordinal Regression Analysis.

The nutritional status of adults before the initiation of chemotherapy in low-income countries has been poorly explored. This study aimed to determine the prevalence of malnutrition and its associated factors before initiating chemotherapy at major cancer centers in Ethiopia. A multicenter cross-sectional study was conducted from February 13 to June 4, 2024, involving 400 adults diagnosed with solid tumors. The Patient-Generated Subjective Global Assessment (PG-SGA) was used to evaluate nutritional status. A multiple ordinal logistic regression model was used to determine associated factors. T…

Effect of intermittent hemodialysis filtration mode on intradialytic hypotension and nutritional status in patients with end-stage renal disease.

INTRODUCTION: This study aimed to investigate the effect of intermittent hemodialysis filtration mode (IHDF) on intradialytic hypotension and nutritional status in patients with end-stage renal disease (ESRD). METHODS: Patients with ESRD who underwent hemodialysis and were treated at our hospital from December 2021 to December 2023 according to the inclusion and exclusion criteria were selected and randomly assigned into two groups: the experimental group (patients received intermittent hemodialysis filtration mode treatment, n = 50) and the control group (patients received conventional maint…

Association between controlling nutritional status score and mortality in older patients with dysphagia in Japan: a retrospective cohort study.

BACKGROUND: Dysphagia confers elevated risks of adverse clinical outcomes. While the Controlling Nutritional Status (CONUT) score has emerged as a prognostic indicator of mortality in critically ill populations, its association with mortality risk among Japanese geriatric patients with dysphagia remains poorly characterized. OBJECTIVE: This retrospective cohort study investigated the prognostic utility of the Controlling Nutritional Status (CONUT) score in geriatric Japanese patients with dysphagia. METHODS: Clinical data from 236 consecutive dysphagia patients admitted to a tertiary care ce…

Exploring the role of human papillomavirus (HPV) status in body composition and nutritional features in patients with oropharyngeal cancer.

BACKGROUND AND AIMS: Patients with oropharyngeal squamous cell carcinoma (OPSCC) are highly prone to malnutrition and sarcopenia due to the … HPV-related patients had higher body mass index (27.3 vs 21.9 kg/m2; p < 0.001) and better baseline nutritional status (p = 0.023), but no differences in skeletal muscle index (SMI, p = 0.103) compared to HPV-unrelated patients. At 3- and 6-months post-treatment the two groups showed similar SMI and total adipose tissue index loss (p > 0.05 for both). HPV status was …

The prognostic impact of preoperative nutritional status on postoperative complications and overall survival in patients with resectable pancreatic cancer.

PURPOSE: The aim of the study is to demonstrate the prognostic impact of preoperative nutritional status indicators, including prognostic nutritional index (PNI), hemoglobin-albumin-lymphocyte-platelet (HALP) score, sarcopenia index (SI), and bone mineral density (BMD) values, on postoperative complications and survival in patients with resectable pancreatic cancer (PC). MATERIALS AND METHODS: The medical data and computed tomography (CT) images of 85 patients who undergone surgery for PC between January 2017 and 2023 were evaluated retrospectively. Patients were grouped according to the pres…

Self-Reporting Cutaneous Leishmaniasis Patients and Nutritional Status: A Study of the Host Factor in Remote Areas of Ethiopia.

BACKGROUND: Leishmania aethiopica is the leading cause of cutaneous leishmaniasis (CL) in Ethiopia. Different clinical manifestations might be related to host immunity, which itself can be influenced by the host's nutritional status. However, there is limited evidence that associates nutritional status with CL in Ethiopia. We investigated the relationship between clinical variables of CL and malnutrition. METHODS: A retrospective study was conducted in June 2024. Patient data was analyzed from those treated for CL and screened for nutrition from January 2022 to May 2024 at Tefera Hailu and Ad…

Impact of Vomer Flap on Nutritional Status in Infants With Cleft Lip and Palate: A Multicenter Retrospective Cohort Study.

ObjectiveTo determine the effect of early hard palate closure by means of a Vomer flap (VF) on the nutritional status of children with cleft lip and palate.DesignMulticenter retrospective cohort study.SettingThree referral centers for oral clefts.Patients, ParticipantsNonsyndromic children with UCLP or BCLP.Interventions: Early hard palate closure with a VF at cheiloplasty around 3 months versus isolated cheiloplasty, both followed by palatoplasty around 9 to 10 months.Main Outcome Measure(s)Anthropometric measures (weight and height) and related weight-for-age and height-for-age Z-scores at t…

Changes in nutritional status and associations with physical and clinical outcomes in acute myeloid leukemia patients during intensive chemotherapy.

BACKGROUND/OBJECTIVES: Patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) often receive medical nutrition therapy (MNT) during intensive remission-induction treatment. Since little is known about changes in nutritional status, specifically body composition, in this patient population, these changes and their associations with physical and clinical outcomes were assessed. SUBJECTS/METHODS: In this multicenter prospective observational study, newly diagnosed AML/MDS patients who received intensive remission-induction chemotherapy, routine dietary counseling by a dietic…