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Necrotizing fasciitis and toxic shock-like syndrome caused by group B streptococcus.

A recent increase in reports of necrotizing fasciitis resulting from group B streptococcus has alerted physicians to a possible concomitant increase of toxic shock-like syndrome. We report the second case of group B streptococcus causing necrotizing fasciitis and toxic shock-like syndrome. A black woman, aged 52 years, with newly diagnosed diabetes mellitus had necrotizing fasciitis type II of the left groin. Hypotension, elevated bilirubin and liver enzymes, and adult respiratory distress syndrome rapidly developed. Because group B streptococcus was isolated from a normally sterile site, the …

Eosinophilic fasciitis following idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia and Hashimoto's disease.

OBJECTIVE: To investigate the impact of post-activation potentiation (PAP) induced by resisted sled sprint at different loads on the subsequent 30 m ice push sled performance of Chinese skeleton athletes, and to identify the resisted sled sprint load that most effectively enhances PAP for Chinese skeleton athletes. METHODS: Seven elite athletes from the Chinese skeleton team participated in four tests with more than 48 h intervals. During the tests, on the first test, athletes completed a 40 min standard warm-up, rested for 6 min, and then performed a 30 m test. On the second, third, and four

Fournier's gangrene: a clinical presentation of necrotizing fasciitis after bone marrow transplantation.

Three patients with ANLL developed Fournier's gangrene as an early complication after allo-BMT (two cases) and auto-BMT (one case); two patients were in first CR, the third had resistant disease. Patients developed fever, perineal pain, swelling and blistering of the genital area. Pseudomonas aeruginosa was isolated from the lesions and patients received systemic antibiotic therapy, surgical debridement and medication with potassium permanganate solution. Two patients made a complete recovery although one died of sepsis. The third had progressive involvement of the abdominal wall and later die

[Eosinophilia-myalgia syndrome with fasciitis and interstitial myositis after L-tryptophan administration].

We describe a 53-year-old women with eosinophilia-myalgia syndrome who suddenly developed severe persistent myalgias of her arms, legs, back … electrophysiological examinations were consistent with sensory neuropathy and myositis. Remarkable fasciitis and interstitial myositis were present in a biopsy specimen (from skin to muscle) taken from her thigh. However, eosinophilic infiltrates were rare. Angiography revealed an apical obstructive cardiomyopathy. In this paper, we describe the clinical f …

[Eosinophilic fasciitis. A recently reported oligotopic connective tissue inflammation. A case report].

A 25 year old suffering from eosinophilic fasciitis is reported. This patient showed periostitis at some bones and myatrophy of thenar and hypothenar besides the typical manifestations related to the involvement of fascia and nearby tissues. On the whole these manifestations reduced the patient's mobility seriously. The typical humoral findings of eosinophilic fasciitis were present, i. e. remarkable eosinophilia, hypergammaglobulinemia with rise of Ig G, and inflammatory serum alterations. Furthermore an increase urinary hydroxyproline excretion was found which means an altered collagen metab…

Reconstruction After Necrotizing Fasciitis: A Timing-Based Algorithm for the Plastic Surgeon.

Survival after necrotizing fasciitis has improved, producing a growing population of survivors whose function and appearance are determined by reconstruction. Guidance on reconstructive timing and technique, however, remains limited. This structured narrative review synthesizes evidence from PubMed/MEDLINE on reconstruction after necrotizing fasciitis from the perspective of the plastic surgeon and proposes a practical, timing-based algorithm. Its central thesis is that reconstruction is planned from the first debridement: wound-bed readiness and patient physiology, rather than a preferred tec…

A Case of Cervical Necrotising Fasciitis Precipitated by Hypopharyngeal Squamous Cell Carcinoma.

Cervical necrotising fasciitis (CNF) is a rare but life-threatening soft tissue infection of the head and neck, associated with high morbidity and mortality despite advances in disease detection and antimicrobial therapy. It most commonly arises from odontogenic or pharyngeal sources, and presentation secondary to underlying head and neck malignancy is uncommon. We report the case of a 54-year-old woman who presented with rapidly progressive anterior neck swelling, subcutaneous emphysema, and septic shock. Cross-sectional imaging demonstrated extensive gas-forming infection involving multiple …

Antibiotic Selection and Outcomes in Patients With Monomicrobial and Polymicrobial Vibrio Necrotizing Fasciitis.

BACKGROUND: Necrotizing fasciitis (NF) caused by Vibrio species is a rapidly progressing, life-threatening infection. The purposes of this study were to characterize polymicrobial Vibrio NF and compare its clinical features, microbiology, antimicrobial therapy, and outcomes with those of monomicrobial Vibrio NF, and to evaluate the effective usage of empirical antibiotics. METHODS: One hundred and ninety-four patients surgically confirmed with Vibrio NF were retrospectively reviewed, in which 180 (92.8%) patients were infected by Vibrio vulnificus. There were 179 patients (92.3%) with a monom…

Eosinophilic Fasciitis in Pediatric Patients: A Rare but Distinct Autoimmune Fibrosing Disorder.

Eosinophilic fasciitis (EF), or Shulman syndrome, first described in 1974, is a rare fibrosing disorder characterized by painful, symmetric swelling and progressive woody induration of skin and subcutaneous tissues. Although the pathogenesis remains unclear, EF is considered immune-mediated, often triggered by physical exertion, infections, or medications. Pediatric EF, a particularly uncommon subset, can exhibit distinct clinical features, including pronounced extracutaneous manifestations, unpredictable disease progression, and variable therapeutic responses. Clinical presentations range fro…

Eosinophilic fasciitis: a comprehensive systematic review of clinical, histologic, and therapeutic perspectives.

BACKGROUND: Eosinophilic fasciitis (EF) is a rare autoimmune disorder within the sclerodermatous disease spectrum, characterized by inflammation and fibrosis of the subcutaneous fat and fascia, often accompanied by peripheral eosinophilia. Although its exact etiology remains uncertain, potential triggers include intense physical exertion, infections, malignancies, and drug exposure - most recently, immune checkpoint inhibitors such as anti-PD-1/PD-L1 agents. Histopathological findings consistently reveal eosinophilic infiltration and fibrosis of subcutaneous fat and fascia. Corticosteroids rem…

An unusual case of IgG4-related disease presenting as lower limb fasciitis.

Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory condition that can affect nearly any organ. We report an unusual case of IgG4-RD presenting as gradually progressing bilateral lower limb fasciitis in a 29-year-old male patient. He was initially diagnosed with lower limb cellulitis; however, the symptoms did not improve with long courses of intravenous antibiotics. Autoimmune screen was negative and there were no features to suggest an underlying atypical infection. Subsequent cross-sectional imaging demonstrated deep fasciitis in both lower legs and a deep in…

Дело о фульминантном некротизирующем фасиите верхней конечности в иммунокомпрометированном пациенте.

Некротизирующий фаскиит (NF) — редкий, чрезвычайно агрессивный и угрожающий конечностям и жизни инфекция мягких тканей, требующая хирургического вмешательства. Диагноз часто задерживается неспециализированными ранними исследованиями, и иммунокомпромиссные пациенты подвергаются особому риску в связи с хладнокровными, атипичными представлениями. Мы представляем случай 70-летнего мужчины с отдаленной историей множественных миелом, обработанных трансплантацией стволовых клеток, который разработал большой NF правой верхней конечности в течение 24 часов после небольшой тупой травмы. Несмотря на появ

Совпадение в аннотации оригинала
Necrotizing fasciitis (NF) is a rare, extremely aggressive, and limb-and-life-threatening soft tissue infection requiring emergent surgical intervention. Diagnosis is often delayed by nonspecific early findings, and immunocompromised patients are at particular risk for fulminant, atypical presentations. We present a case of a 70-year-old male with a remote h…

Necrotizing fasciitis caused by Actinomyces europaeus: a case report and literature review.

BACKGROUND: Necrotizing fasciitis caused by Actinomyces europaeus is rare, here we report a case of necrotizing fasciitis caused by Actinomyces europaeus infection in a 43-year-old adult male from China. CASE PRESENTATION: A 43-year-old man with inguinal necrotizing fasciitis who initially received clindamycin but showed poor response. Subsequent cultures revealed polymicrobial infection, and therapy was switched to piperacillin-tazobactam with repeated surgical debridement. He was later discharged on oral amoxicillin-clavulanate for three months and fully recovered without recurrence. This ca…

Characteristic contrast-enhanced MRI findings of nodular fasciitis and their chronological change.

PURPOSE: This study aimed to identify characteristic contrast-enhanced MRI features of nodular fasciitis that aid in differentiating it from malignant tumors and to evaluate their chronological changes. MATERIALS AND METHODS: We analyzed 62 histologically confirmed nodular fasciitis lesions from 61 patients. All patients underwent T2-weighted and post-contrast MRI. Non-enhancing patterns were categorized as follows: type 1 (homogeneous enhancement), type 2 (central non-enhancement), type 3 (heterogeneous non-enhancement), and type 4 (predominantly non-enhancing). Type 4 was subdivided into ty…

Insights into necrotising fasciitis: A prospective pilot study in a Tertiary Care Hospital.

INTRODUCTION: Necrotising fasciitis, commonly referred to as "flesh-eating disease," is a rapidly spreading soft tissue infection characterised by extensive necrosis of the skin, subcutaneous tissue, and fascia while sparing the underlying muscle. Despite its low overall incidence, it is a significant soft tissue infection due to its rapid spread and associated high mortality risk. MATERIALS AND METHODS: This prospective pilot study aims to analyse 25 consecutive cases of necrotising fasciitis to assess various aspects, including age and sex incidence, microbial flora, role of co-morbidities …

Core Muscle Weakness May Be a Risk Factor for the Development of Plantar Fasciitis.

Introduction Plantar fasciitis (PF) is a common diagnosis in the United States and worldwide. Core musculature helps to stabilize the spine in order to prevent buckling and provide optimal production of motion. Core deficits may contribute to lower extremity injury through kinematic changes in lower extremity movement. There may be an association between a theoretical core muscle deficit and the subsequent development of symptomatic PF. Methods A retrospective case-control study was designed using the Truven Health MarketScan® database. The incidence of new, concurrent PF diagnoses was determi…

Analgesia With Epidural Anesthesia in Lower-Leg Necrotizing Fasciitis: A Case Report.

Appropriate methods have not been established despite the necessity of analgesia for debridement in cases of necrotizing fasciitis. A 45-year-old woman was hospitalized for necrotizing fasciitis due to Streptococcus pyogenes. Rapid debridement and antibiotic treatment enabled the patient's quick discharge from the intensive care unit. However, after discharge, she began experiencing considerable pain in the left lower leg, which hindered adequate debridement, resulting in the persistence of necrotic tissue. Epidural anesthesia was administered to alleviate pain and enable debridement. Epidural…

MRSA Necrotizing Fasciitis of the Neck and Chest in a 3-Month-Old Infant.

We report the case of a 3-month-old infant with methicillin-resistant Staphylococcus aureus (MRSA) necrotizing fasciitis of the neck and chest complicated by bacteremia, pneumonia, and mediastinitis, which required multiple surgical debridements, including median sternotomy. The case is unsual given the patient's age and causative pathogen, and underscores the importance of early diagnosis, timely surgical intervention, and multidisciplinary collaboration to ensure survival.