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Sleep disturbances in patients with vasculitis.

OBJECTIVE: Research on sleep patterns in individuals with vasculitis remains limited. This SleepVasc study aimed to 1) evaluate sleep disturbances and a range of sleep health dimensions in individuals with vasculitis, and 2) identify potential risk factors for sleep problems/disturbances/disorders. METHODS: SleepVasc was conducted through a cross-sectional, web-based survey within the Vasculitis Patient-Powered Research Network. Participants completed these questionnaires: Epworth Sleepiness Scale, Functional Outcomes of Sleep Questionnaire-10, Multivariable Apnea Prediction Questionnaire, an…

[Sleep and neurodevelopment: a timely subject].

Neurodevelopmental disorders (NDDs) include a heterogeneous group of conditions characterized by an alteration of neurodevelopmental processes leading to a significant impact on the individual's personal, social, and/or academic functioning. Among the many comorbidities frequently associated with NDDs, sleep disturbances play a major role, affecting between 30% and 80% of concerned people. This article explores the various links between sleep and NDDs through a review of the scientific literature highlighting the most recent research in this area, with a particular focus on two neurodevelopmen…

[Dementia and Sleep: A Bidirectional Relationship].

Sleep-waking is regulated by numerous sleep- and wake-promoting nuclei in the brain and biological clocks (suprachiasmatic nucleus). In dementia, organic damage occurs in the brainstem, hypothalamus, and thalamus, where these nuclei and their neural projections are concentrated, resulting in severe insomnia, hypersomnia, and irregular sleep-wake patterns. Numerous cohort studies have strongly suggested that sleep disturbances, such as impaired sleep quality and hypersomnia, may serve as early indicators or risk factors for the onset of dementia. Until recently, the neuropathological mechanisms…

Hypnotic suggestions in the modulation of sleep.

Sleep is vital for physical and mental health and plays an important role in general well-being. Given the high prevalence of sleep disturbances in contemporary society, developing effective sleep-enhancing interventions, including non-pharmacological approaches such as hypnosis, is important. In this chapter, we will first discuss the nature of sleep and the factors that can disturb it. We will present scientific evidence on how hypnotherapy can improve sleep parameters and disturbances. This will be followed by the presentation of experimental studies highlighting the potential of hypnotic s…

Sleep Medicine-What's in a Name?

Sleep medicine has matured into a recognised medical discipline, characterised by defined diagnostic concepts, evidence-based treatments, and significant progress in understanding sleep physiology and disorders. Sleep and its disturbances impact virtually every aspect of health and well-being. The major categories of sleep disorders include insomnia, neurological and psychiatric sleep disorders, sleep-disordered breathing, and paediatric sleep disorders. Breakthroughs in biomedical research have deepened clinical expertise across each of these domains. Although sleep medicine has historically …

The Mechanisms of Magnesium in Sleep Disorders.

Sleep is a highly elaborate biological occurrence, necessitating the combined action and participation of diverse brain regions. The sleep-wake cycle is regulated by a multitude of factors, including various hormones produced by the hypothalamus and external stimuli. Sleep disorders can accelerate the progression of numerous diseases or directly trigger the onset of many health conditions. However, the specific regulatory mechanisms remain elusive. In recent years, the role of magnesium in sleep disorders has garnered considerable attention. Magnesium not only reduces the excitability of the n…

Роль сна в множественном склерозе.

Множественный склероз (MS) — расстройство, связанное с автоматическим иммунитетом и затрагивающее главным образом молодых людей. Высокая распространенность этого заболевания и его воздействие на качество жизни пациентов побудили исследователей изучить этиопатогенез этого заболевания для выявления возможных модифицируемых факторов и соответствующих эффективных стратегий вмешательства. Недавние гипотезы говорят о том, что этиопатогенез MS является многофакторным и включает в себя факторы, связанные с иммунной системой, нейроинфламмацией и нейродегенерацией. В этом сценарии сон, как представляетс

Совпадение в аннотации оригинала
Multiple Sclerosis (MS) is an autoimmunity-related disorder that mainly affects young adults. The high prevalence of the disease and its imp … es factors related to the immune system, neuroinflammation and neurodegeneration. In this scenario, sleep seems to have a close indirect relationship with MS, through its relationship with each of those factors and given the high incidence of sleep disorders in the MS population. Furthermore, given the growing interest of research in the mechanisms unde …

The Role of Sleep in Cardiovascular Disease.

PURPOSE OF REVIEW: Sleep is an important component of cardiovascular (CV) health. This review summarizes the complex relationship between sleep and CV disease (CVD). Additionally, we describe the data supporting the treatment of sleep disturbances in preventing and treating CVD. RECENT FINDINGS: Recent guidelines recommend screening for obstructive sleep apnea in patients with atrial fibrillation. New data continues to demonstrate the importance of sleep quality and duration for CV health. There is a complex bidirectional relationship between sleep health and CVD. Sleep disturbances have syst…

Coffee and sleep: Benefits and risks.

Consuming coffee, a widely enjoyed beverage with caffeine, can impact the central nervous system and disturb sleep if taken too close to bedtime. Caffeine impacts sleep by slowing the onset, blocking adenosine receptors, lowering deep sleep levels, disrupting sleep patterns, and lessening rapid eye movement sleep. Although coffee can help with alertness in the morning, it may disturb sleep in the evening, particularly for individuals who are sensitive to caffeine. To enhance the quality of sleep, reduce the consumption of caffeine in the afternoon and evening, refrain from drinking caffeine be…

Sleep and critical illness: a review.

Critical illness and stays in the Intensive Care Unit (ICU) have significant impact on sleep. Poor sleep is common in this setting, can persist beyond acute critical illness, and is associated with increased morbidity and mortality. In the past 5 years, intensive care clinical practice guidelines have directed more focus on sleep and circadian disruption, spurring new initiatives to study and improve sleep complications in the critically ill. The global SARS-COV-2 (COVID-19) pandemic and dramatic spikes in patients requiring ICU level care also brought augmented levels of sleep disruption, the…

Obstructive sleep apnea for the rhinologist.

PURPOSE: Obstructive sleep apnea (OSA) is a ubiquitous disease defined by repetitive partial or complete cessation of airflow during sleep caused by upper airway collapse. Otolaryngologists play a crucial role in the management of OSA, which is rapidly evolving with the advent of new surgical techniques and medical devices. Here we review the medical and surgical treatment options for OSA with a focus on unique considerations for patients with OSA who undergo nasal, sinus, and skull base surgery. RECENT FINDINGS: Treatment of OSA includes both nonsurgical and surgical options. Positive airway…

[Properties of milk in sleep induction].

Sleep induction and its quality are issues of growing concern because its deterioration affects a large number of people and poses a risk to their well-being and quality of life and long-term health. There are several factors involved in the problem, but nutrition is one of them and in particular milk consumption has often been linked to sleep habits, sometimes as a promoter and sometimes as an inhibitor. The purpose of this review is to examine the matter further. On reaching the brain, tryptophan is the basis for the synthesis of serotonin and melatonin, which improve the induction and quali…

The role of sleep in neuromuscular disorders.

Sleep represents a major frontier both in clinical myology and as a new possibility for delivering treatment to neuromuscular patients since various neuromuscular cases present a variable degree of disordered sleep and such conditions should be diagnosed and prevented, i.e., sleep apnea and hypoxemia. These sleep disorders are present in dystrophinopathies and in various types of limb-girdle muscular dystrophies (LGMD). Excessive daytime sleepiness (EDS) is found in patients affected by spastic paraparesis or cerebellar ataxia but is rather common in both myotonic dystrophy type 1 and 2, and t…

Sleep in the intensive care unit.

PURPOSE OF REVIEW: Sleep is particularly important for critically ill patients. Here, we review the latest evidence on how sleep and circadian disruption in the intensive care unit (ICU) affects physiology and clinical outcomes, as well as the most recent advances in sleep and circadian rhythm promoting interventions including therapeutics. RECENT FINDINGS: On a molecular level, clock genes dysrhythmia and altered immunity are clearly linked, particularly in sepsis. Melatonin may also be associated with insulin sensitivity in ICU patients. Clinically, changes in sleep architecture are associa…

[Sleep medicine in psychiatry and psychotherapy].

Sleep medicine is a cross-disciplinary subject with high relevance for psychiatry and psychotherapy. The three most common sleep disorders (insomnia, sleep apnea syndrome and restless legs syndrome) are presented here with practical relevance. Cognitive behavioral therapy is the treatment of choice for insomnia, whereas symptomatic drug treatment (especially with GABA receptor agonists) should be used with caution. Sleep-related breathing disorders have a high prevalence of around 24% among psychiatric inpatients in Germany. Typical symptoms of obstructive sleep apnea syndrome should lead to a…

[Sleep medicine for the ENT specialist].

Sleep-related breathing disorders can be divided into obstructive and central sleep apnea, and hypoventilation syndromes. The diagnosis is made according to an algorithm in which clinical symptoms and a polygraphy or polysomnography usually point the way. After initial diagnosis of the most common obstructive sleep apnea, conservative therapies such as positive airway pressure therapy (PAP therapy), positional therapy, and/or mandibular advancement splint are used in many cases, supplemented by treatment of risk factors. If PAP therapy is not possible, more detailed diagnosis of airway obstruc…

Narrative review of sleep and stroke.

Sleep disorders, such as sleep-disordered breathing (SDB), insomnia or restless legs syndrome (RLS), are common in the general population and after stroke. In some cases, sleep disturbances are pre-existing, but can also appear de novo as a direct consequence of brain damage or due to stroke-related complications. Furthermore, some sleep conditions may act as a risk factor of stroke. This review explores the available evidence of the two-way relationship between sleep and stroke. Cardiovascular physiological changes during sleep are described, as well as the evidence on the relationship betwee…