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The study of loading mode with in-vitro fatigue testing for mitral annuloplasty ring.

To maintain the physiological dynamics of the mitral annulus, mitral annuloplasty rings (MAR) must be flexible. Enhanced flexibility implies decreased resistance to fatigue and potential for fatigue fracture. This study established new methods to test the flexible fatigue life of MAR in-vitro using numerical analysis; the purpose is that the fatigue test could reflect the real stress distribution in-vivo. Based on the conventional test methods (C1, D1), this paper presents a novel test method (C2, D2). Four testing methods for open-end annuloplasty rings (C1, C2) and closed-end annuloplasty ri…

Creatine Monohydrate as an Effective Supplement for Muscular Fatigue in an Ehlers-Danlos Patient.

Patients with Ehlers-Danlos syndrome (EDS) frequently report symptoms such as chronic pain and muscular fatigue that can heavily impact their quality of life. The treatment for many of the physical symptoms of EDS is focused on supportive care, which may include physical therapy and exercise programs. However, many patients will experience difficulty in deriving benefits from these activities due to significant pain and fatigue from physical activity. We report a case of a 39-year-old female with a history of EDS whose physical capabilities were severely impacted by their chronic pain and fati…

The effect of breathing exercises on fatigue in tuberculosis patients: a randomized controlled trial.

OBJECTIVE: This study was conducted as a randomized controlled trial to investigate the effect of breathing exercises on fatigue in patients diagnosed with tuberculosis. METHODS: The tuberculosis patients included in the study were divided into two groups: intervention (26) and control (28) by a program established after the power analysis. After the researcher informed the patients in the intervention group about breathing exercises, including diaphragmatic and pursed lip breathing, they were taught, and the first exercise was practiced. Then, the patients in this group did breathing exercis…

Наблюдение за сезонными колебаниями усталости в множестве склероза зависит от измерительного прибора.

Обсуждается вопрос о том, способствуют ли сезонные колебания внешней температуры утомлению MS, что является одним из наиболее распространенных симптомов болезни. Мы проанализировали влияние сезона на базовые уровни усталости в наших случайных, контролируемых плацебо, перекрестных испытаниях с двойным слепым слоем, лечении усталости от метилфенидата, Modafinil и амантадина в MS (TRIUMPANT-MS), проведенных на двух участках с очень различным климатом. Усталость измерялась с использованием двух проверенных инструментов (изменение степени усталости (MFIS) и оценка усталости Neuro-QoL). Оценки УМФС

Совпадение в аннотации оригинала
It is debated whether seasonal variation in outside temperature contributes to MS fatigue, one of the disease's most common symptoms. We analyzed the effect of the season on the baseline fatigue levels in our randomized, placebo-controlled, crossover, double-blind trial, Treatment of Fatigue with Methylphenidate, Modafinil, and Amantadine in MS (TRIUMPHANT-M…

Brain and muscle activity during fatiguing maximum-speed knee movement.

Although the underlying mechanisms behind upper limb (e.g., finger) motor slowing during movements performed at the maximum voluntary rate have been explored, the same cannot be said for the lower limb. This is especially relevant considering the lower limb's larger joints and different functional patterns. Despite the similar motor control base, previously found differences in movement patterns and segment inertia may lead to distinct central and peripheral manifestations of fatigue in larger joint movement. Therefore, we aimed to explore these manifestations in a fatiguing knee maximum movem…

The influence of symptom severity and fatigue on sleep quality in patients with myasthenia gravis.

INTRODUCTION: Myasthenia gravis is a rare and chronic autoimmune disease. The study aimed to evaluate the influence of symptom severity and fatigue on sleep quality in patients with myasthenia gravis. METHODS: This was a cross-sectional study, and the population consisted of patients with MG throughout Turkey. The study was completed with 163 patients on 1 April and 31 July 2022. RESULTS: It was found that the mean Myasthenia Gravis-Activities of Daily Living Scale score was 6.32 ± 3.9, the Fatigue Severity Scale score was 37.01 ± 23.26, and the total Pittsburgh Sleep Quality Index score was…

The effect of physical exercise on fatigue in systemic lupus erythematosus: a systematic review.

OBJECTIVE: Fatigue is a prominent and disabling manifestation that impairs the quality of life of Systemic Lupus Erythematosus (SLE) patients both physically and mentally. The majority of SLE patients reports fatigue as an unmet need. Physical exercise could help SLE patients to reduce fatigue and improve quality of life. METHODS: A systematic review was conducted to analyse the effectiveness of physical exercise interventions to reduce fatigue in SLE patients. PubMed, EMBASE, Web of Science: Core Collection, the Cochrane Library, CINAHL via EBSCO, and PEDro were searched (March 2021 to Octob…

The effect of fatigue on postural control in individuals with multiple sclerosis: a systematic review.

BackgroundFatigue is the most disabling symptom for individuals with multiple sclerosis (MS), which can significantly affect postural control (PC) by impairing the ability of the central nervous system to modulate sensory inputs and coordinate motor responses. This systematic review aimed to investigate the effect of fatigue on PC in individuals with MS..MethodsThis systematic review is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline and registered in PROSPERO with ID CRD42022376262. A systematic search was performed in the Web of…

The Influence of Fatigue on the Characteristics of Physiological Tremor and Hoffmann Reflex in Young Men.

The aim of the study was to determine the relationship between changes in physiological tremor after exercise and changes in the traction properties of the stretch reflex indirectly assessed using the Hoffmann reflex test. The research involved 19 young men practicing canoe sprint (age 16.4 ± 0.7 years, body mass 74.4 ± 6.7 kg, body height 182.1 ± 4.3 cm, training experience 4.8 ± 1.6 years). During resting tests, Hoffmann reflex measurements were performed from the soleus muscle, physiological tremor of the lower limb, and the blood lactate concentration was determined. Then, a graded test wa

In vitro fracture and fatigue resistance of monolithic zirconia crowns fabricated by stereolithography.

STATEMENT OF PROBLEM: Stereolithography has been used to print zirconia ceramic crowns with acceptable dimensional accuracy and fracture force. However, studies that compared the fatigue resistance of zirconia crowns fabricated by stereolithography are lacking. PURPOSE: The purpose of this in vitro study was to compare the fracture and fatigue resistance of monolithic zirconia crowns printed by stereolithography apparatus (SLA) and digital light processing (DLP) with those of zirconia crowns milled by computer numerical control (CNC). MATERIAL AND METHODS: A total of 120 crowns were fabricat…

On the fatigue life of dental implants: Numerical and experimental investigation on configuration effect.

Dental implants have seen widespread and successful use in recent years. Given their long-term application and the critical role of geometry in determining fracture and fatigue characteristics, fatigue assessments are of utmost importance for implant systems. In this study, nine dental implant system samples were subjected to testing in accordance with ISO 14801 standards. The tests included static evaluations to assess ultimate loads and fatigue tests conducted under loads of 270 N and 230 N at a frequency of 15 Hz, aimed at identifying fatigue failure locations and fatigue life. Fatigue life…

The relationship of centralized pain in fibromyalgia syndrome with sleep, fatigue and quality of life.

OBJECTIVES: The aim of this study was to examine the central role of pain in patients' lives by evaluating the relationship between the centralization of pain and clinical and functional parameters. METHODS: Adult patients aged 18-70 diagnosed with FM were included in the study. The Fibromyalgia Impact Questionnaire (FIQ) was used to assess the severity of FM, and the Centrality of Pain Scale (COPS) was used to assess pain centralization. The European Quality of Life Scale 5 Dimension (EQ-5D) assessed quality of life, the Jenkins Sleep Scale (JSS-TR) sleep, and the Beck Depression Inventory (

The vicious cycle of physical inactivity, fatigue and kinesiophobia in patients with fibromyalgia syndrome.

This study aims to determine the association between fatigue, kinesiophobia, disease severity, and physical inactivity by comparing fibromyalgia syndrome (FMS) patients with healthy controls. Pain and fatigue are significant barriers to the participation in functional activities. Inactivity is a result of fatigue, but exercise is the foundation of FMS treatment. This case-control study included a total of 203 participants (107 patients with FMS and 96 healthy volunteers). The fibromyalgia impact questionnaire, the fatigue severity scale, the international physical activity questionnaire, and t…

Can infrared thermography serve as an alternative to assess cumulative fatigue in women?

Muscle fatigue can limit performance both in sports and daily life activities. Consecutive days of exercise without a proper recovery time may elicit cumulative fatigue. Although it has been speculated that skin temperature could serve as an indirect indicator of exercise-induced adaptations, it is unclear if skin temperature measured by infrared thermography (IRT) could be an outcome related to the effects of cumulative fatigue. In this study, we recruited 21 untrained women and induced cumulative fatigue in biceps brachii over two consecutive days of exercise. We measured delayed onset muscl…

Perfusion Imaging of Fatigue and Time-on-Task Effects in Patients With Parkinson's Disease.

Fatigue is a highly prevalent and debilitating non-motor symptom in Parkinson's disease (PD), yet its' neural mechanisms remain poorly understood. Here we combined arterial spin labeling (ASL) perfusion functional magnetic resonance imaging (fMRI) with a sustained mental workload paradigm to examine the neural correlates of fatigue and time-on-task effects in PD patients. Twenty-one PD patients were scanned at rest and during continuous performance of a 20-min psychomotor vigilance test (PVT). Time-on-task effects were measured by the reaction time changes during the PVT and by self-reported f…

Validity and reliability of the German multidimensional fatigue inventory in spinal muscular atrophy.

OBJECTIVE: Fatigue is a common and burdensome symptom of spinal muscular atrophy. Given its complex interactions, different dimensions of fatigue need to be investigated. The Multidimensional Fatigue Inventory is a widely used instrument that captures five distinct dimensions. The aim of this study was to investigate the validity and reliability of the German Multidimensional Fatigue Inventory in spinal muscular atrophy and to evaluate the presence of clinically relevant fatigue. METHODS: One hundred and forty adult spinal muscular atrophy patients completed the Multidimensional Fatigue Inven…

Validity and reliability of the Tampa Kinesiophobia-Fatigue Scale in patients with multiple sclerosis.

BACKGROUND: Kinesiophobia can be a barrier for physical activity in patients with multiple sclerosis (PwMS) and it can develop as a result of fear and avoidance reactions due to fatigue. However, there is no valid and reliable scale available to assess kinesiophobia due to fatigue in PwMS. AIMS: To investigate the test-retest reliability and construct validity of the Tampa Scale of Kinesiophobia-Fatigue (TSK-F) in PwMS. METHODS: Eighty-seven PwMS were included in the study. In addition to TSK-F, the following measurements were used for construct validity: Expanded Disability Status Scale (ED…

Experimental study on the influence of mental fatigue on risk decision-making of miners.

Mental fatigue increases risk-taking behavior. Using data collected between June 15 and August 6, 2020, this study investigates the impact of miners' mental fatigue on risk decision-making to improve risk prevention and prediction abilities, and to reduce the occurrence of coal mine safety accidents. A total of 273 and 33 people participated in the preliminary and formal experiments, respectively. The participants, coal miners, visited a lab thrice to complete the pre-experiment, Balloon Analog Risk Task (BART), and Iowa Gambling Task (IGT). On the BART, mental fatigue displayed a significantl…

Exploring the role of the left DLPFC in fatigue during unresisted rhythmic movements.

Understanding central fatigue during motor activities is important in neuroscience and different medical fields. The central mechanisms of motor fatigue are known in depth for isometric muscle contractions; however, current knowledge about rhythmic movements and central fatigue is rather scarce. In this study, we explored the role of an executive area (left dorsolateral prefrontal cortex [DLPFC]) in fatigue development during rhythmic movement execution, finger tapping (FT) at the maximal rate, and fatigue after effects on the stability of rhythmic patterns. Participants (n = 19) performed six…