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Surface expression of an immunodominant malaria protein B cell epitope by yellow fever virus.

The yellow fever 17D virus (YF17D) has several characteristics that are desirable for the development of new, live attenuated vaccines. We approached its development as a vector for heterologous antigens by studying the expression of a humoral epitope at the surface of the E protein based on the results of modelling its three-dimensional structure. This model indicated that the most promising insertion site is between beta-strands f and g, a site that is exposed at the external surface of the virus. The large deletion of six residues from the fg loop of the E protein from yellow fever virus, c…

Гепаратная сульфатная связь с вирусом инфекционного денге типа 2 и вирусом желтой лихорадки.

Вирус денге типа 2 и вирус Желтой лихорадки - это артропроподовые ароматизаторы, вызывающие геморрагическую лихорадку у людей. Идентификация вирусных рецепторов имеет важное значение для понимания патогенеза флавивируса. Цель этой работы заключалась в изучении роли сульфата клеточной гепары в адсорбции инфекционных желтых лихорадок и вирусов денге типа 2. Вирусное соединение оценивалось путем адсорбирования вируса к клеткам, стирания незамысловатого вируса, высвобождения вируса привязки к клеткам путем замерзания/отталкивания, а затем заклеивания высвобожденного инфекционного вируса. Лечение к

Совпадение в аннотации оригинала
Dengue virus type 2 and Yellow fever virus are arthropod-borne flaviviruses causing hemorrhagic fever in humans. Identification of virus receptors is important in understanding flavivirus pathogenesis. The aim of this work was to study the role of cellular heparan sulfate in the adsorption of infectious Yellow fever and Dengue type 2 viruses. Virus attachmen…

[The combined measles-yellow fever vaccination in African infants aged 6 to 10 months].

The compared tolerance and immunogenicity of vaccines against yellow fever and measles, separately administered or combined, have been evaluated in a group of 319 children from North Cameroon, aged 6-10 months. The clinical tolerance was excellent for both the isolated and the combined vaccines. The seroconversion level is higher after administration of the combined vaccine: 89.9% against 83.5% for measles, 95.8% against 92.6% for yellow fever, but these results are not significantly different. 30 days after vaccination, the antibody titers are higher with the combined vaccine: 215.3 against 1…

Dengue-2 vaccine: virological, immunological, and clinical responses of six yellow fever-immune recipients.

Six male volunteers, previously immunized with yellow fever vaccine, were inoculated subcutaneously with a live, attenuated dengue-2 virus (PR-159/S-1) candidate vaccine. Five recipients developed viremia 8 or 9 days after vaccination, which lasted 1 to 10 days. The onset of viremia was followed by fever in three people, transient leukopenia in four, and an erythematous rash in one. One volunteer developed an oral temperature of 38.8 degrees C with headache, myalgia, fatigue, and photophobia suggestive of mild dengue fever. All five viremic volunteers developed fourfold or greater rises in ser…

Morphogenesis of yellow fever virus in Aedes aegypti cultured cells. II. An ultrastructural study.

The growth and intracytoplasmic development of two yellow fever virus strains (wild and French neurotropic) were studied in Aedes aegypti cells (clone C 17). Despite a longer period of latency for the vaccine virus, infected cells appeared similar. The cisternae of the rough endoplasmic reticulum (RER) were swollen and formed vesicles which contained the virus. This RER appeared to be the predominant locus of viral synthesis and maturation. Cytopathic effect appeared when the cells were filled with vesicles, and it was characterized by cell degeneration and lysis.

A yellow fever epizootic in Zika Forest, Uganda, during 1972: Part 2: Monkey serology.

During the 1972 yellow fever epizootic in Zika Forest, Uganda, sera from 21 monkeys shot in a number of forests around the Entebbe area were tested for the presence of a number of arbovirus antibodies. All sera were tested for antibodies against Chikungunya (CHIK), O'nyong-nyong (ONN), Zika, yellow fever (YF) West Nile (WN) and Wesselsbron (WESS) by the haemagglutination-inhibition (HI) test. Because of the crossreaction within the flaviviruses (group B arboviruses) mouse protection test (PT) was also carried out on the sera against YF, WESS and Zika viruses. Serological studies carried out on…

ETIOLOGY OF YELLOW FEVER : X. COMPARATIVE IMMUNOLOGICAL STUDIES ON LEPTOSPIRA ICTEROIDES AND LEPTOSPIRA ICTEROHAEMOORRHAGIAE.

It has been previously reported that a filterable microorganism belonging to the genus Leptospira has been recovered from the blood or organs of human beings suffering from the disease known as yellow fever in Guayaquil, and that the organism, which has been termed Leptospira icteroides, induces in certain experimental animals the characteristic symptoms and lesions observed in the patients from whom it was isolated. It has also been previously shown that the serum from patients recovering from an attack of yellow fever in Guayaquil had the power to agglutinate and dissolve the organism when i…

[Ocular manifestations of emerging arboviruses: Dengue fever, Chikungunya, Zika virus, West Nile virus, and yellow fever (French translation of the article)].

Arboviruses are viral diseases transmitted by mosquitoes and tics bites. They are a major cause of morbidity and sometimes mortality. Their … phthalmological manifestations of Dengue fever, Chikungunya virus, Zika virus, West Nile virus, and yellow fever.

Suspected immune-mediated inflammatory myositis with rhabdomyolysis following yellow fever vaccination: a case report.

BACKGROUND: The yellow fever vaccine is a live-attenuated vaccine with an excellent safety profile; however, rare adverse events have been reported. Musculoskeletal complications, particularly inflammatory myositis with rhabdomyolysis, are exceedingly uncommon and not well characterized in the literature. CASE PRESENTATION: We report a case of a 49-year-old man who developed acute febrile illness, severe myalgia, and progressive proximal muscle weakness 1 week after receiving his first yellow fever vaccination. An extensive diagnostic evaluation was performed. The patient presented with high-…

Yellow Fever Virus Surveillance in Callithrix spp. Marmosets during Epizootic Outbreak, Brazil, 2024-2025.

In 2023, a new yellow fever virus (YFV) lineage was introduced in São Paulo state, Brazil. During July 2024-June 2025, nine Callithrix penicillata marmosets tested YFV-positive, showing high viral loads and characteristic organ lesions. Those results highlight the need to include these animals in multispecies surveillance strategies for early YFV detection.