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Recommendations for the analysis of leading indicators in epidemic surveillance.

Leading indicator analyses, a type of time series analysis, are frequently used to assess how epidemic surveillance signals relate to one another. Strong leading indicators can drive early, and better decisions in public health systems. We conducted a narrative review of leading indicator studies and evaluated methodological limitations in their reporting and analysis, which we used to generate recommendations in retrospective surveillance analyses. Achievable recommendations are provided based on the reporting and analysis components of real-time epidemic time series analysis. We provide cont