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Calcium Isotopic Evidence for Vulnerable Marine Ecosystem Structure Prior to the K/Pg Extinction.

The collapse of marine ecosystems during the end-Cretaceous mass extinction involved the base of the food chain [1] up to ubiquitous vertebr … Mosasaurids are unusually diverse and locally abundant in the Maastrichtian phosphatic deposits of Morocco, and with large sharks and one species of elasmosaurid plesiosaurian recognized so far, contribute to an overabundance of apex predators [3, 7, 14, 15]. For this reason, high local diversity of marine reptiles exhibiting different body masses and a …

Home treatment of haemarthrosis with recombinant activated factor VII in patients with haemophilia A or B and inhibitors: experience from developing countries.

Home therapy for uncomplicated mild/moderate bleeding can decrease healthcare burden, promote self-esteem, reduce complications, and provide near-normal quality of life. To evaluate recombinant activated factor VII (rFVIIa) as home therapy for joint bleeds in Algeria, Morocco, Oman, Saudi Arabia, and United Arab Emirates. Twenty-seven patients aged more than 2 years with congenital haemophilia and inhibitors were monitored for up to 8 months after a first haemarthrosis episode treated with rFVIIa. Assessments were made by patients/caregivers with a standardized diary. The main measures include…

Improving the prognosis of pediatric Hodgkin lymphoma in developing countries: a Moroccan Society of Pediatric Hematology and Oncology study.

BACKGROUND: The event-free survival (EFS) of children with Hodgkin lymphoma (HL) exceeds 80% in high income countries (HIC), but little is known about this rate in developing countries. PROCEDURE: A prospective national protocol for children with classical HL was implemented in Morocco to increase EFS by careful risk stratification, providing each cycle of therapy on time, decreasing treatment abandonment, improving communication among healthcare providers, and improving data collection. Patients were stratified into a favorable risk group (Ann Arbor stages I and II, no B symptoms, no bulky d…

Bacteriological features of infectious spondylodiscitis at Mohammed V Military Teaching Hospital of Rabat.

To review the bacteriological features of infectious spondylodiscitis and provide recommendations for the initial therapy which remains empi … necrosis in total concordance with TB culture. TB is the most frequent cause of spondylodiscitis in Morocco. Our study found the same frequency for non-specific and specific germs. Empirical treatment must take into account S. aureus and M. tuberculosis.

Culex pipiens, an experimental efficient vector of West Nile and Rift Valley fever viruses in the Maghreb region.

West Nile fever (WNF) and Rift Valley fever (RVF) are emerging diseases causing epidemics outside their natural range of distribution. West … rth Africa to transmit WNV and the avirulent RVFV Clone 13 strain. Mosquitoes collected in Algeria, Morocco, and Tunisia during the summer 2010 were experimentally infected with WNV and RVFV Clone 13 strain at titers of 10(7.8) and 10(8.5) plaque forming units/mL, respectively. Disseminated infection and transmission rates were estimated 14-21 days follow …

[Results of the surgical closure of ventricular septal defects of various ages: report of 30 cases].

OBJECTIVE: To appreciate short and midterm results of patients after surgical closure of the ventricular septal defect. MATERIAL AND METHODS: The study is retrospective and took place in the department of cardiovascular surgery "B", Ibn-Sina hospital, Rabat, Morocco. Between 1995 and 2005, 30 patients underwent a surgical closure of ventricular septal defect. Eighteen patients (60%) were males and twelve (40%) were females with a mean age of 10 years (18 months-36 years). Seven patients (23%) were older than 16 years. All of ventricular septal defects were type 2, unique and most of them peri…

Genome-wide analysis for micro-aberrations in familial exstrophy of the bladder using array-based comparative genomic hybridization.

OBJECTIVE: Exstrophy of the bladder (EB) is part of the bladder-exstrophy-epispadias complex (BEEC). Because familial occurrence of BEEC is rare, exogenous factors are thought to play a major role in the etiology of most BEEC cases. We aimed to investigate a possible genetic basis of BEEC in a consanguineous kindred of Moroccan origin with three members showing the same phenotypic expression of BEEC. PATIENTS AND METHODS: The three affected males (two cousins and their maternal uncle) all presenting with nonsyndromic classic EB, were born in Morocco or The Netherlands. One Moroccan patient ha…

Folic acid knowledge and use in a multi-ethnic pregnancy cohort: the role of language proficiency.

OBJECTIVE: To investigate the role of language proficiency as determinant of folic acid knowledge and use in a multi-ethnic pregnancy cohort. DESIGN: Prospective cohort study. SETTING AND POPULATION: Pregnant women from Amsterdam attending obstetric care for their first antenatal visit. Number approached: 12,373 women, response rate: 67% (8266 women aged 14-49 years). Ethnicity was based on the country of birth: the Netherlands, Surinam, Antilles, Turkey, Morocco, Ghana, other non-Western and other Western countries. MAIN OUTCOME MEASURES: Knowledge about and use of folic acid supplements i…

[Vascular complications of infective endocarditis: a retrospective analysis of 18 cases].

OBJECTIVES: Among 82 patients hospitalized for infective endocarditis between June 1995 and June 2001 at the cardiology B unit of the Rabat University Hospital Morocco, 18 (22%) had one or more vascular complications. We present here a retrospective analysis. PATIENTS AND METHODS: The cohort included 12 men and 6 women, mean age 22 years. Infective endocarditis had grafted on a pre-existing cardiopathy among 17 patients: rheumatic heart disease (n=14), mechanical prosthetic valve (n=2), congenital heart disease (n=1). RESULTS: For 12 patients, vascular disease was the only complication, 1 ha…

[Implantation of catgut plus Laser for treatment of trigeminal neuralgia].

BACKGROUND AND AIM: Type 2 diabetes is prone to numerous comorbidities resulting from complex mechanisms involving hyperglycemia, insulin resistance, low-grade inflammation and accelerated atherogenesis. The purpose of the present study was to investigate these disorders and their associated risk factors according to patient sex in a population of type 2 diabetics in North-Eastern Morocco. METHODS: This study was conducted in a medical analysis laboratory over a 1-year period from 01/10/2018 to 01/10/2019. This epidemiological study was carried out on 830 subjects aged 18 and over. Quantitati…

Parietal hydatid cyst of the rectus abdominis muscle: case report and literature review.

INTRODUCTION AND IMPORTANCE: Hydatid disease is a zoonotic infection caused by the larval stage of Echinococcus granulosus. It remains endemic in Morocco and represents a significant public health concern. Although the liver and lungs are the most frequently affected organs, muscular involvement is rare. This report aims to describe an unusual case of a hydatid cyst in the rectus abdominis muscle and highlight the role of imaging in diagnosis and management. CASE PRESENTATION: A 37-year-old woman presented with a progressively enlarging hypogastric swelling evolving over 5 months. Clinical ex…

Hyalomma aegyptium: наблюдаемое глобальное распределение, импортированные образцы, предпочтительные носители и векторная компетентность.

Тортоза тикает Hyalomma aegyptium (Linnaeus, 1758) — трихостовой клещ, в основном поражающий черепахи рода Testudo. Была составлена база данных, в результате чего в Палерктике было установлено 557 географических привязок H. aegyptium. Этот набор данных впервые охватывает весь диапазон H. aegyptium. Таким образом, площадь естественного распределения H. aegyptium простирается от Марокко на северо-западе Африки до Кыргызстана в Центральной Азии от 10°W-73° E до 28-46° N, что отражено в обзорной карте и четырех подробных картах, охватывающих Северную Африку, Балканы, Ближний Восток и Ближний Восто

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The tortoise tick Hyalomma aegyptium (Linnaeus, 1758) is a three-host tick, predominantly infesting land tortoises of the genus Testudo. A d … f H. aegyptium for the first time. Thus, the natural distribution area of H. aegyptium extends from Morocco in northwestern Africa to Kyrgyzstan in Central Asia between 10° W-73° E and 28-46° N, which is shown in an overview map and four detailed maps covering North Africa, the Balkans, the Near East, and the Middle East. In addition, documented findings …

Рамадан постится в множестве склерозов: систематический обзор.

Во время рамадана, девятого месяца исламского календаря, мусульмане должны воздерживаться от еды, питья, курения и сексуальной деятельности с восхода солнца до захода солнца. Возможные последствия соблюдения рамадана у пациентов с множественным склерозом (МС) являются сложной проблемой, которая рассматривается в настоящем систематическом обзоре. МЕТОДЫ: В соответствии с методами JBI и PRISMA в базах данных PubMed, Scopus, Embase и Web of Science были проведены широкие обыски, и были собраны клинические данные о вероятных последствиях постовых операций в Рамадане у пациентов, страдающих НР. Обз

Совпадение в аннотации оригинала
BACKGROUND AND AIMS: During Ramadan, the ninth month of the Islamic calendar, Muslims should abstain from eating, drinking, smoking, and sex … study settings were Iran (two studies) and Egypt; and one multicenter study was conducted in Egypt, Morocco, and Saudi Arabia. Ramadan fasting was not found to be associated with increasing frequency of MS relapsing or worsening of disability. Also, evidence suggests benefits regarding the quality of life and cognitive domain score of modified fatigue imp …

Социально-демографические и клинические детерминанты качества жизни марокканского народа с множественным склерозом.

КАЧЕСТВО ЖИЗНИ (КОЛ) людей с множественным склерозом (МС) значительно ниже, чем КОЛ людей с другими хроническими заболеваниями. Управление QOL не должно ограничиваться только клиническими аспектами, но и факторами, изменяющими QOL. Цель этого исследования состояла в том, чтобы выявить социально-демографические и клинические детерминанты QOL у людей с MS. МЕТОДЫ: В период с 2022 по 2023 год было проведено перекрестное исследование, в котором приняли участие 200 человек в возрасте 18 лет и старше, набранных в медицинской больнице Университета им. Хасана II в Фесе, Марокко. Оценка QOL проводилась

Совпадение в аннотации оригинала
BACKGROUND: The quality of life (QOL) of people with multiple sclerosis (MS) is considerably poorer than the QOL of people with other chroni … 200 participants aged 18 and over recruited from the Hassan II University Medical Hospital in Fez, Morocco. QOL assessment was performed using the Arabic version of the Multiple Sclerosis Quality of Life-54 (MSQOL-54) questionnaire. Univariate analysis using Student t test, analysis of variance, and Pearson correlation was performed, followed by multiple …

Genetic insights of H9N2 avian influenza viruses circulating in Mali and phylogeographic patterns in Northern and Western Africa.

Avian influenza viruses (AIVs) of the H9N2 subtype have become widespread in Western Africa since their first detection in 2017 in Burkina F … istance lineage dispersal event of the H9N2 virus to Western Africa, likely to have originated from Morocco in 2015, shaping the westward diffusion of the H9N2 virus. Our study highlights the need for long-term surveillance of H9N2 viruses in poultry populations in Western Africa, which is crucial for a better understanding of virus evolution and effectiv …

Navigating diagnostic challenges-distinguishing malignant melanoma and clear cell sarcoma of soft tissues: a case report and review of the literature.

BACKGROUND: Within the spectrum of melanocytic-differentiated tumors, the challenge faced by pathologists is discerning accurate diagnoses, … al and molecular analyses. CASE PRESENTATION: A compelling case unfolds as a 25-year-old male from Morocco, initially misdiagnosed with malignant melanoma, experiences tumor recurrence on the second toe. With no history of trauma or familial neoplasia, the patient's clinical journey is explored, emphasizing the importance of detailed clinical examination …

Inflammatory breast cancer: Epidemiologic data and therapeutic results.

Since the early description more than a century ago, inflammatory breast cancer (IBC) remains an aggressive disease, with a different geographic repartition, with the highest ones incidence reported in the North of Africa (Tunisia, Algeria, Morocco, and Egypt), and the lowest incidence in Western countries (USA, Europe…). In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to…

Peritoneal hydatidosis secondary to an asymptomatic liver hydatid cyst rupture: A case report.

INTRODUCTION AND IMPORTANCE: Hydatid cysts, caused by Echinococcus granulosus, are a significant public health problem in regions such as Tunisia and Morocco. These cysts primarily affect the liver and lungs but can also involve the spleen, kidneys, bones, and brain. Peritoneal hydatidosis, involving the formation of hydatid cysts in the peritoneal cavity, is a rare manifestation of this disease. This case report aims to highlight the presentation, diagnostic process, and surgical management of a primary peritoneal hydatid cyst. CASE PRESENTATION: A 73-year-old asymptomatic woman with no sign…

Unusual Presentation of Non-Hodgkin Lymphoma of Two Cases: Case Report.

UNLABELLED: Pregnancy and/or the puerperium involve social, physiological and psychological changes that make women more vulnerable to mental disorders such as anxiety and depression, even more so if these develop in stressful contexts such as the pandemic. The aim of this study is to identify factors associated with the risk of postpartum anxiety and depression during the COVID-19 pandemic. A cross-sectional study was conducted among postpartum women (n = 69) who gave birth between March 2020 and March 2021 in Melilla, a Spanish cross-border city with Morocco whose borders were closed, making…

Prevalence and Risk Factors of Retinopathy in Type 1 Diabetes: A Cross-Sectional Study.

Introduction Diabetic retinopathy (DR) is a severe complication of diabetes. It remains a major cause of visual impairment and blindness, es … t of Endocrinology, Diabetology, and Nutrition of the University Hospital Center Mohammed VI Oujda, Morocco. Data were collected from medical records and analyzed by binary logistic regression using IBM Corp. Released 2012. IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp. Results The average age of our patients was 24.2 ± 11.4 years. T …