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Classification of Health-Related Social Media Posts: Evaluation of Post Content-Classifier Models and Analysis of User Demographics.

BackgroundThe increasing volume of health-related social media activity, where users connect, collaborate, and engage, has increased the significance of analyzing how people use health-related social media.ObjectiveThe aim of this study was to classify the content (eg, posts that share experiences and seek support) of users who write health-related social media posts and study the effect of user demographics on post content.MethodsWe analyzed two different types of health-related social media: (1) health-related online forums-WebMD and DailyStrength-and (2) general online social networks-Twitt

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… | 33 (6.6) Advertisement | N/A | N/A | 26 (5.2) | 70 (14.0) Personal opinion | N/A | N/A | 35 (7.0) | 84 (16.8) Educational material | N/A | N/A | 36 (7.2) | 137 (25.7) Bot Filtering We examined the impact of automated accounts (ie, bots ) on our study using OSoMe’s Botometer (formerly BotOrNot, Indiana …

Иммунитет в нейромодуляции: исследование нейронных и иммунных путей в расстройствах мозга.

Иммунитет четко регулирует функцию мозга. Она непосредственно участвует в патологических процессах таких нейродегенеративных заболеваний, как болезнь Паркинсона и Альцгеймера, посттравматические заболевания, множественный склероз, травма головного мозга и психические расстройства (большое расстройство организма, серьезное депрессивное расстройство (МДС), расстройства тревожности, расстройства психоза и шизофрения, а также расстройства нервного развития (НРД). Нейромодулирование в настоящее время является одной из ведущих терапевтических стратегий лечения этих расстройств, однако пока мало что

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… TgCRND8 mice expressing Swedish (KM670/671 NL) and Indiana (V717 F) APP mutations under the control of the hamster prion (PrP) promoter received either scyllo-inositol or an initial gFUS MRI treatment administering BAM-10 prior to scyllo-inositol treatment. …

Best of JACC: Case Reports From ACC.23.

This dedicated issue of JACC: Case Reports highlights the top ranked Complex Clinical Cases from the ACC 2023 Scientific Sessions. These cases were reviewed and selected by a committee of peers in the months leading up to the annual meeting. These reviewers were ACC members with no affiliation to the JACC: Case Reports Editorial Board. While the cases were presented at the meeting and included in the formal Abstract Book from ACC, they have not been published elsewhere. These cases illustrate how the ACC can be a place for cardiovascular professionals to come together to learn, grow, and share

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… Cook, Indiana University School of Medicine, Indianapolis, IN, USA Background Cardiovascular disease is the most common cause of pregnancy-related mortality. Pregnant women with symptomatic, severe aortic stenosis (AS) carry the greatest complication risk. …

Scoping Review and Meta-Analysis Suggests that Cannabis Use May Reduce Cancer Risk in the United States.

Introduction:Cannabis smoke contains carcinogens similar to tobacco, in addition to compounds with antitumor activity. Cannabis use reduces the risk of obesity and cannabinoids inhibit chronic inflammation, known causes of cancer. The net effect of Cannabis use on cancer risk is not known. Objective: To examine the association between Cannabis use and cancer risk in the United States. Methods: Identify and analyze published data on cancer risk in Cannabis users. Results: A total of 55 data points, consisting of risk ratios of cancer in Cannabis users and nonusers, were identified from 34 studi

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… Funding Information This research was supported by a sabbatical leave from Indiana University South Bend. No other funding support was utilized in this project. References 1. Siegel RL , Miller KD , Jemal A . Cancer statistics, 2019 . …

Corneal Epithelial Findings in Patients with Multiple Myeloma Treated with Antibody-Drug Conjugate Belantamab Mafodotin in the Pivotal, Randomized, DREAMM-2 Study.

IntroductionPatients with relapsed or refractory multiple myeloma (RRMM) represent an unmet clinical need. Belantamab mafodotin (belamaf; GSK2857916) is a first-in-class antibody-drug conjugate (ADC; or immunoconjugate) that delivers a cytotoxic payload, monomethyl auristatin F (MMAF), to myeloma cells. In the phase II DREAMM-2 study (NCT03525678), single-agent belamaf (2.5 mg/kg) demonstrated clinically meaningful anti-myeloma activity (overall response rate 32%) in patients with heavily pretreated disease. Microcyst-like epithelial changes (MECs) were common, consistent with reports from oth

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… site: Abramson Cancer Center; MD Anderson Cancer Center, Houston; University of Maryland at Baltimore; Princess Margaret Cancer Centre; Emory University, Winship Cancer Institute; Icahn School of Medicine at Mount Sinai; Universitätsklinikum Tübingen; University of Wisconsin, Carbone Cancer Center; Indiana …

The International Headache Congress - IHS and EHF joint congress 2021 : Virtual. 8-12 September 2021.

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Current state of CAR-T therapy for T-cell malignancies.

Chimeric antigen receptor T-cell (CAR-T) therapy has been approved for relapsed/refractory B-cell lymphomas and greatly improves disease outcomes. The impressive success has inspired the application of this approach to other types of tumors. The relapsed/refractory T-cell malignancies are characteristic of high heterogeneity and poor prognoses. The efficacy of current treatments for this group of diseases is limited. CAR-T therapy is a promising solution to ameliorate the current therapeutic situation. One of the major challenges is that normal T-cells typically share mutual antigens with mali

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… Antigen target | Trial identifier | Trial phase | Disease | Recruitment status | Country | Institution CD4 | NCT04162340 | I | T-NHL | Recruiting | China | Peking University Shenzhen Hospital | NCT03829540 | I | T-cell malignancies | Not recruiting | United States | Indiana University | NCT04219319 …

Прогресс в оказании поддержки в проведении обзора по множественным болезням, связанным с миеломой.

Множественная миелома (ММ) — неизлечимая порча плазменных клеток, характеризующаяся увеличением производства моноклонального иммуноглобулина. Пациенты с ММ подвержены высокому риску возникновения осложнений, связанных с заболеваниями. Остеолитическая болезнь костей one - из наиболее распространенных осложнений, связанных с заболеваниями, которые приводят к хронической боли и патологии скелета, что в значительной степени способствует высоким уровням заболеваемости и смертности среди пациентов с ОМ. Помимо стандартной антиММ-терапии, для улучшения качества жизни пациентов, страдающих ММ, необход

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… Indiana Health Law. Rev. 2023;20:63–89. doi: 10.18060/27180. 79. Neuropathic Pain in Adults: Pharmacological Management in Non-Specialist Settings. [(accessed on 20 February 2025)]; Available online: https://www.ncbi.nlm.nih.gov/books/NBK552848/pdf/Bookshelf_NBK552848.pdf . 80. …

BioBERT-powered synergy: advanced bibliometric and molecular insights into prostate cancer bone metastasis.

BACKGROUND: Prostate cancer (PC) is a leading cause of male cancer mortality, with bone metastasis (BM) being a frequent and debilitating complication. Despite therapeutic advancements, the molecular mechanisms underlying BM remain poorly understood. This study aims to bridge this gap by integrating bibliometric analysis with bioinformatics to provide a comprehensive overview of the academic trends and molecular profiles associated with prostate cancer bone metastasis (PCBM). METHODS: We conducted a bibliometric analysis to identify key contributors in PCBM research from 2004 to 2024 with adv

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… . | 43 | USA | Massachusetts Gen Hosp | 9 | Shore, Neal D | 3,260 | USA | Carolina Urol Res Ctr 10 | Sartor, Oliver | 42 | USA | Tulane Canc Ctr | 10 | Guise, Theresa A | 2,997 | USA | Indiana Univ Sch Med Lotka’s Law is considered as one of the most noted laws in bibliometric studies ( 23 ). …

The Genetics and Epigenetics of 22q11.2 Deletion Syndrome.

Chromosome 22q11.2 deletion syndrome (22q11.2del) is a complex, multi-organ disorder noted for its varying severity and penetrance among those affected. The clinical problems comprise congenital malformations; cardiac problems including outflow tract defects, hypoplasia of the thymus, hypoparathyroidism, and/or dysmorphic facial features. Additional clinical issues that can appear over time are autoimmunity, renal insufficiency, developmental delay, malignancy and neurological manifestations such as schizophrenia. The majority of individuals with 22q11.2del have a 3 Mb deletion of DNA on chrom

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… Nelson (Indiana University School of Medicine) for helpful discussions and information. We also thank Dr. Pratibha Bhalla and Ms. Fatma Coskun (UT Southwestern Medical Center) for reviewing the figures in the manuscript. References Alfano D., Altomonte A., Cortes C., Bilio M., Kelly R. …

The Medicare experience with end-stage renal disease: trends in incidence, prevalence, and survival.

This article presents a detailed account of the incidence, prevalence, and survival experience of people with end-stage renal disease (ESRD) covered by Medicare. The number of new entrants into the ESRD program has risen since its inception. This increase is greatest for people whose cause of renal failure is primary hypertensive disease or diabetic nephropathy. The program incidence rates for black people is 2.8 times that of white people. Incidence is highest for persons 65 to 69 years of age. Total patient survival is 44 percent 5 years after renal failure onset. Total Medicare enrollment f

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… 25.3 | 57 District of Columbia | 674 | 125.0 | 185 | 152 | 9.7 | 64 Florida | 8594 | 921.0 | 107 | 5457 | 381.7 | 70 Georgia | 5084 | 482.0 | 95 | 3256 | 178.3 | 55 Hawaii | 897 | 86.7 | 97 | 307 | 17.0 | 55 Idaho | 878 | 38.3 | 44 | 684 | 29.3 | 43 Illinois | 11243 | 807.3 | 72 | 8585 | 402.7 | 47 Indiana …

2023 Scientific Session of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), Montréal, Canada, 19 March–April 1 2023: Posters

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… Matthew Ritter, MD, MHPE; Comprehesive Hernia Program, Department of Surgery, Indiana University School of Medicine, Indianapolis IN Background: Smoking, obesity, diabetes mellitus, and COPD are known risk factors for surgical site occurrences (SSO) following open ventral hernia repair. …

Evaluating patient-reported outcomes in randomized controlled trials of targeted therapy and/or immunotherapy for liver cancer: a scoping review.

ObjectiveTo assess the reporting characteristics and quality of patient-reported outcomes (PROs) in randomized controlled trials (RCTs) of targeted therapy and/or immunotherapy for liver cancer.MethodsWe systematically searched six electronic databases for relevant RCTs published in English or Chinese from inception to April 17, 2025. The reporting quality of PROs was assessed using the CONSORT-PRO extension and the CONSORT 2010 guidelines.ResultsWe included 64 RCTs with 8,494 participants. Of these, 14 studies were confirmatory studies, 31 studies were exploratory studies and 19 studies were

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… Footnotes Edited by: Wen Yang , Eastern Hepatobiliary Surgery Hospital, China Reviewed by: Fabrizio Di Costanzo , Newcastle University, United Kingdom Archita Desai , Indiana University, United States Data availability statement The original contributions presented in the study are included in the …

Историческое развитие иммуноэндокринных концепций психических расстройств и их терапии.

Отношения между центральной нервной, иммунной и эндокринной системами являются предметом психиатрических исследований, особенно в области депрессии и шизофрения. У поля длинные предтечи. Наблюдаемые явления, связанные с этими отношениями, восходят к неолитической эпохе. Теории иммуноэндокринной системы в самом широком смысле записаны в древности. В 19th Крепелин и Вагнер-Джаурег сообщили о первых клинических наблюдениях у пациентов психиатрических учреждений. Von Bestow, Эддисон и Кушинг описали психические симптомы у пациентов, страдающих эндокринными заболеваниями. :: 20th откровение века с

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… Sharp in Indiana had 180 male prison inmates castrated to reduce their sexual drive in order to, on the one hand, but not only, prevent sex offences, but also, on the other to prevent masturbation and reproduction of “mental defectives” [ 14 , 15 ]. …

Abstracts From JADPRO Live 2019: Washington State Convention Center • Seattle • October 24-27.

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… LeFebvre, MSN, RN, RN-BC, AOCN®, Oncology Nursing Society; David DeRemer, PharmD, BCOP, FCCP, FHOPA, University of Florida College of Pharmacy; Joshua Nubla, PharmD, National Community Oncology Dispensing Association; Julianne Orr, PharmD, BCOP, Indiana University Health; Michael Reff, RPh, MBA, National …

Early detection of sporadic pancreatic cancer: summative review.

Pancreatic cancer (PC) is estimated to become the second leading cause of cancer death in the United States by 2020. Early detection is the key to improving survival in PC. Addressing this urgent need, the Kenner Family Research Fund conducted the inaugural Early Detection of Sporadic Pancreatic Cancer Summit Conference in 2014 in conjunction with the 45th Anniversary Meeting of the American Pancreatic Association and Japan Pancreas Society. This seminal convening of international representatives from science, practice, and clinical research was designed to facilitate challenging interdiscipli

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… Registries (and often genetic studies) exist at the following centers or agencies in the United States: Creighton University, Columbia University, Dana Farber Cancer Center, Indiana University, Johns Hopkins, Mayo Clinic, Memorial Sloan Kettering Cancer Center, Mt Sinai Hospital–Icahn School of Medicine …

Identification of broad anti-coronavirus chemical agents for repurposing against SARS-CoV-2 and variants of concern.

Endemic human coronaviruses (hCoVs) 229E and OC43 cause respiratory disease with recurrent infections, while severe acute respiratory syndrome (SARS)-CoV-2 spreads across the world with impact on health and societies. Here, we report an image-based multicycle infection procedure with α-coronavirus hCoV-229E-eGFP in an arrayed chemical library screen of 5440 clinical and preclinical compounds. Toxicity counter selection and challenge with the β-coronaviruses OC43 and SARS-CoV-2 in tissue culture and human airway epithelial explant cultures (HAEEC) identified four FDA-approved compounds with ora

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… For fluidics handling, a Matrix WellMate dispenser and Matrix WellMate tubing cartridges (Thermo Fisher Scientific, Waltham, USA), an Assist Plus pipetting robot (Integra Biosciences AG, Zizers, Switzerland) and an Echo acoustic dispenser (Labcyte Inc., Indiana, USA) were used. …

Резюме, представленные на 32nd Ежегодная конференция Международного общества по изучению качества жизни.

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Abstracts of the 19th International Congress on Neuromuscular Diseases 7th – 11th July 2026

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… Poznań, Poland. 4 MDA ALS & Neuromuscular Center, Department of Neurology, University of California, Irvine, Orange, CA, United States. 5 Lange Neurology, New York, NY, United States. 6 Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Hiroshima, Japan. 7 Neurology Department, Indiana … University School of Medicine, Indiana University Health, Indianapolis, IN, United States. 8 Université Côte d'Azur, Peripheral Nervous System & Muscle Department, Pasteur 2 Hospital, Centre Hospitalier Universitaire de Nice, Nice, France. 9 Department of Neurology, Hanamaki General Hospital, Hanamaki …

The 4th Global Congress on Sickle Cell Disease Abstract Book 2022

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… association of america PI-08: HIGH DISEASE BURDEN, MORBIDITY AND MORTALITY AMONG CHILDREN WITH SICKLE CELL ANAEMIA IN UGANDA NAMAZZI R. 1 , CONROY A. 2 , BOND C. 2 , GOINGS M. 2 , DATTA D. 2 , WARE R. 3 , OPOKA R. 1 , JOHN C. 2 1 Makerere University College of Health Sceinces, Kampala, UGANDA; 2 Indiana … University, Indiana, UNITED STATES; 3 Cincinatti Children’s Hospital Medical Center, Cincinatti, UNITED STATES Purpose: Few studies have described in depth the burden of sickle cell anemia (SCA) related morbidity and mortality in children in Sub Saharan Africa, the continent with the highest burden …