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Воздействие питательных микроэлементов на результаты беременности в развивающихся странах: систематический обзор и метаанализ.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: В развивающихся странах по-прежнему относительно высоки показатели низкой беременности. Недостаток питательных микроэлементов относится к числу факторов, которые играют определенную роль в определении негативных последствий беременности. Цель настоящего исследования заключается в изучении роли дефицита питательных микроэлементов в неудовлетворительных результатах беременности и их связи с здоровьем новорожденных.МЕТОД: Для этого обзора был проведен систематический поиск с использованием программы " Харзинг периш " и публикация программного обеспечения, а также

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… Samimi M Asemi Z Taghizada M Azarbad Z Rahimi-Foroushani A Sarahroodi S Concentrations of serum zinc, hemoglobin and ferritin among pregnant women and their effects on birth outcomes in Kashan, Iran Oman Med J 2012 27 40 5 10.5001/omj.2012.08 22359724 PMC3282140 Samimi M, Asemi Z, Taghizada M, Azarbad … Oman Med J. 2012;27:40–5. 22359724 10.5001/omj.2012.08 PMC3282140 25. …

Sequential inactivated (IPV) and live oral (OPV) poliovirus vaccines for preventing poliomyelitis.

BACKGROUND: Poliomyelitis mainly affects unvaccinated children under five years of age, causing irreversible paralysis or even death. The or … ducted in high-income countries; five in the USA, two in the UK, and one each in Chile, Israel, and Oman. The remaining six RCTs were conducted in middle-income countries; China, Bangladesh, Guatemala, India, and Thailand. We rated all included RCTs at low or unclear risk of bias for randomisation domains, most at high or unclear risk of attrition bias …

Spiritual Needs and Quality of Life of Patients with Cancer.

Background and aimInformation about spiritual needs and quality of life (QoL) is limited in Iranian cancer patients. This study was conducted to determine the relationship between spiritual needs and QoL among cancer patients in Iran.MethodsThis correlational study included a convenience sample of 150 eligible cancer patients who were hospitalized in the oncology wards and outpatient clinics. Using two questionnaires; the spiritual needs survey and the European Organization for Research and Treatment of Cancer QoL Questionnaire-C30 data were collected. The data were analyzed by SPSS software v

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… Sintonen H Hänninen J Taari K Health-related quality of life among breast, prostate, and colorectal cancer patients with end-stage disease Qual Life Res 2014 23 1387 94 24178630 10.1007/s11136-013-0562-y 33 Dehkordi A Heydarnejad MS Fatehi D Quality of life in cancer patients undergoing chemotherapy Oman …

A Case of Light Chain Deposition Disease Leading to Acute Liver Failure and Review of Literature.

Light chain deposition disease (LCDD) is a monoclonal immunoglobulin deposition disease characterized by light chain deposition in soft tissues and viscera, causing systemic organ dysfunction with an underlying lymphoproliferative disorder. While the kidney is the most affected organ, cardiac and hepatic involvement is also seen with LCDD. Hepatic manifestation can range from mild hepatic injury to fulminant liver failure. Herein, we are presenting a case of an 83-year-old woman with a monoclonal gammopathy of undetermined significance (MGUS), who presented to our institution with acute liver …

Анализ тенденций и межнациональный анализ неравноправия в отношении иммунизированных подстрекательских заболеваний у детей и подростков в возрасте от 10 до 24 лет в период с 1990 по 2021 год.

IMID - это хронические подстрекательские заболевания, вызываемые дисрегулированием иммунной системы и затрагивающие многочисленные системы и органы. Дети и подростки в возрасте от 10 до 24 лет относятся к группам повышенного риска, и глобальное бремя является значительным. МЕТОДЫ: Используя самые последние данные о глобальном бремени заболеваний (ГБЗ) 2021 года, мы использовали регрессионный анализ " Компонт " , корреляционный анализ социально-демографического индекса (ИОД) и межнациональный анализ справедливости для разъяснения диспропорциональных различий в бремени ИМНИ среди детей

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… The fastest-growing incidence rate of RA was in Oman (AAPC: 2.2215 [95% CI: 2.1619 to 2.2811, p  = 0.000]), while the fastest declining rate was in Sweden (AAPC: −0.4186 [95% CI: −0.4869 to −0.3503, p  = 0.000]). …

A Monocentric Analysis of Implantable Ports in Cancer Treatment: Five-Year Efficacy and Safety Evaluation.

BACKGROUND: Daily clinical practice requires repeated and prolonged venous access for delivering chemotherapy, antibiotics, antivirals, parenteral nutrition, or blood transfusions. This study aimed to investigate the performance and the safety of totally implantable vascular access devices (TIVADs) over a 5-year follow-up period through a standardized well-trained surgical technique and patient management under local anesthesia. METHODS: In a retrospective, observational, and monocentric study, 70 patients receiving POLYSITE® TIVADs for chemotherapy were included. The safety endpoints focused

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… Complications and Management of Totally Implantable Central Venous Access Ports in Cancer Patients at a University Hospital in Oman. Sultan. Qaboos. Univ. Med. J. 2021;21:e103–e109. doi: 10.18295/squmj.2021.21.01.014. 3. Kulkarni S., Wu O., Kasthuri R., Moss J.G. …

A prospective, multicenter, open-label study of the clinical efficacy of tapentadol extended-release in the treatment of cancer-related pain and improvement in the quality of life of opioid-naïve or opioid-resistant patients.

PurposeThis study aimed to investigate the clinical efficacy of tapentadol extended-release (ER) on pain control and the quality of life (QoL) of patients with moderate to severe chronic cancer pain in clinical practice in Korea.MethodsIn this prospective, open-label, multicenter trial, patients with sustained cancer pain as well as chronic pain, who were or were not using other analgesics were enrolled. Thirteen centers recorded a total of 752 patients during the 6-month observation period, based on the tapentadol ER dose and tolerability, prior and concomitant analgesic treatment, pain inten

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… Jimmy B Jose J Patient medication adherence: measures in daily practice Oman Med J 2011 26 155 159 10.5001/omj.2011.38 22043406 PMC3191684 40. …

Xerostomia due to systemic disease: a review of 20 conditions and mechanisms.

Xerostomia is a common complaint of nearly half of the elderly population and about one-fifth of younger adults. It causes several signs and symptoms, and compromise oral functions and health-related quality-of-life. Multiple reasons are proposed to describe the etiology of xerostomia such as local factors, psychogenic factors, and systemic diseases. In order to manage xerostomia effectively, identification of the main causality is mandatory. The aim of this review was to present systemic diseases leading to xerostomia with their mechanisms of action. We used various general search engines and

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… Bakianian Vaziri P Vahedi M Mortazavi H Abdollahzadeh Sh Hajilooi M Evaluation of salivary glucose, IgA and flow rate in diabetic patients: A case-control study J Dent (Tehran) 2010 7 13 8 21998770 PMC3184719 13 Olokoba AB Obateru OA Olokoba LB Type 2 diabetes mellitus: a review of current trends Oman …

Клинические характеристики, лабораторные меры и качество жизни как предвестники соблюдения лекарств в множестве миеломы.

Соблюдение лекарств в миеломе (ММ) является одним из ключевых факторов, определяющих результаты лечения, однако его взаимосвязь с качеством жизни, о котором сообщают пациенты, по-прежнему недостаточно изучена. Мы провели многоцентральное перекрестное исследование по всему спектру five Больницы на Западном берегу2018–2025), зачисление 250 Взрослые с MM на активном лечении. При поступлении в школу пациенты закончили ЭОРТК QLQ-MY20 для оценки КОЛ для конкретных заболеваний, и one Месяц спустя была проведена оценка участия в программе с использованием Moricy Mediction. Scale-4 (В тыс.MMAS-4). Боль

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… Jimmy B Jose J Patient medication adherence: measures in daily practice Oman Med. J. 2011 26 3 155 159 10.5001/omj.2011.38 22043406 PMC3191684 Jimmy, B. & Jose, J. Patient medication adherence: measures in daily practice. Oman Med. …

Невидимый кризис: выявление скрытого воздействия загрязнения воздуха внутри помещений на здоровье человека - аналитическое исследование.

Загрязнение воздуха внутри помещений представляет собой серьезную проблему для здоровья населения, особенно в таких странах, как Индия, где миллионы людей подвергаются воздействию вредных загрязнителей в своих домах и на рабочих местах. В этом аналитическом обзоре рассматриваются многогранные последствия загрязнения воздуха внутри помещений для здоровья людей, обобщены данные, полученные в ходе различных проектов исследований и в географических регионах. На основе всеобъемлющей стратегии поиска, которая позволила 320 записи, в которых 120 в Паубмеде, 108 Веб-сайт науки, и 92 В SCOPUS. Ten были

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… Al-Shidi HK Ambusaidi AK Sulaiman H Public awareness, perceptions and attitudes on air pollution and its health effects in Muscat, Oman J Air Waste Manag Assoc 2021 71 1159 74 33989134 10.1080/10962247.2021.1930287 44. …

A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes.

Background and aimsAs a curative procedure, hematopoietic stemcell transplantation (HSCT) is an approved treatment for many malignant orbenign hematologic and non-hematologic diseases. There are different outcomes of HSCT, as well as several parameters influencing these outcomes.MethodsWe had searched scientific sources like Web ofScience and PubMed with a combination of keywords such as HSCT, engraftment,survival, outcomes, etc. Totally, 80 articles were included.ResultsHere we have reviewed the effective factors onmain outcomes of HSCT including engraftment, survival, graft versus hostdiseas

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… Oman Med J. 2019;34(1):34. 5. Fürst D, Neuchel C, Tsamadou C, Schrezenmeier H, Mytilineos J. HLA matching in unrelated stem cell transplantation up to date. Transfusion Med Hemother. 2019;46(5):326‐336. 6. Cruz‐Tapias P, Castiblanco J, Anaya J‐M. …

Efficacy and safety of biosimilar Peg-filgrastim after autologous stem cell transplant in myeloma and lymphoma patients: a comparative study with biosimilar Filgrastim, Lenograstim, and originator Peg-filgrastim.

Data about biosimilar Peg-filgrastim (bioPEG) in autologous stem cell transplant (ASCT) are still scarce. The aim of this study has been to assess efficacy and safety of bioPEG among lymphoma and myeloma patients undergoing ASCT, comparing these data with historical controls receiving other G-CSFs. Furthermore, an economic evaluation has been included to estimate the savings by using bioPEG. This is a prospective cohort study comparing lymphoma and myeloma patients undergoing ASCT and receiving bioPEG (n = 73) with three historical consecutive cohorts collected retrospectively who received oth

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… Oman Med J. 2019;34:34–43. doi: 10.5001/omj.2019.06. 26. Cooper KL, Madan J, Whyte S, et al. Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis following chemotherapy: systematic review and meta-analysis. BMC Cancer. 2011;11:404. doi: 10.1186/1471-2407-11-404. 27. …

Effectiveness of biosimilar pegfilgrastim in patients with multiple myeloma after high-dose melphalan and autologous stem cell transplantation.

Multiple myeloma (MM) is the main indication for autologous stem cell transplantation (ASCT). Novel supportive therapies (e.g., granulocyte colony-stimulating factor) have significantly improved post-ASCT-related mortality; however, data on biosimilar pegfilgrastim-bmez (BIO/PEG) in this setting is lacking. This prospective cohort study compared Italian patients with MM who received BIO/PEG post-ASCT with data collected retrospectively from historical control groups from the same center who received either filgrastim-sndz (BIO/G-CSF) or pegfilgrastim (PEG; originator). The primary endpoint was

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… Oman Med J. 2019;34:34–43. doi: 10.5001/omj.2019.06. 28. Bellon A, Wang J, Skerjanec A, Velinova M, Dickerson D, Sabet A, et al. …

Treatment Satisfaction and Burden of Illness in Patients with Newly Diagnosed Multiple Myeloma.

ObjectivesThis observational study identified attributes of patient-reported satisfaction with therapy for multiple myeloma (MM), described the treatment-related time burden and indirect costs, and investigated the effect of administration route (oral vs. injectable) on these outcomes among patients with newly diagnosed MM (NDMM) and among caregivers.MethodsPatients residing in the USA with a self-reported diagnosis of NDMM were recruited from PatientsLikeMe, MyelomaCrowd, and Facebook (16 December 2016 and 6 July 2017) to complete an electronic survey including questions on treatment experien

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… Oman Med J. 2014;29(1):3–7. doi: 10.5001/omj.2014.02. 6. Efficace F, Cottone F, Abel G, et al. Patient-reported outcomes enhance the survival prediction of traditional disease risk classifications: an international study in patients with myelodysplastic syndromes. …

Psychometric properties of two physical activity questionnaires, the AQuAA and the PASE, in cancer patients.

BackgroundThis study aimed to evaluate the reliability and validity of two self-report physical activity (PA) questionnaires - the AQuAA (Activity Questionnaire for Adults and Adolescents) and PASE (Physical Activity Scale for the Elderly) - in cancer patients.MethodsTest-retest reliability was determined by administering the questionnaires twice within 5 days. Intraclass correlation coefficient (ICC), standard error of measurement (SEM) and smallest detectable difference (SDD) were calculated. Construct validity was determined by comparing the questionnaire results with ActiGraph acceleromete

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… Dinger MK, Oman RF, Taylor EL, Vesely SK, Able J. Stability and convergent validity of the Physical Activity Scale for the Elderly (PASE) J Sports Med Phys Fitness. 2004;44:186–192. Hendelman D, Miller K, Baggett C, Debold E, Freedson P. …

Скрытые расходы PEG-rhG-CSF на аутлогическую трансплантацию стволовых клеток для недавно диагностированной множественной миеломы.

Оценить клиническую ценность полиэтилен-гликолизированного рекомбинированного человеческого гранулоцита-стимулирующего фактора (PEG-rhG-CSF) для гематопоэтического восстановления после аутологической трансплантации стволовых клеток (ASCT) у недавно диагностированных пациентов с множественными миеломами (NDMM). В настоящем исследовании анализируются данные, полученные от 70 Пациенты NDMM, проходящие ACCT, с 33 получение PEG-rhG-CSF и 37 Принимаю RG-CSF. Среднее время нейтрофильного и тромбоцитного оплодотворения, медианное переливание продуктов крови, неблагоприятные реакции, связанные с лечени

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… Oman Med. J. 34 , 34–43. 10.5001/omj.2019.06 (2019). 4. Aladağ Karakulak, E. et al. CD34+ hematopoietic progenitor cell dose as a predictor of engraftment and survival in multiple myeloma patients undergoing autologous stem cell transplantation. Turk. J. Med. …

Частота и коррелация перинатальной депрессии.

ЦЕЛЬ: Этот систематический обзор систематических обзоров призван дать первую глобальную картину распространенности и корреляции перинатальной депрессии и изучить общие черты и расхождения в литературе. МЕТОДЫ: Seven :: Поиск баз данных с момента их создания и до апреля 2022. Полнотекстовая проверка и извлечение данных проводились независимо two Для оценки методологического качества использовались исследователи и инструмент AMSTAR. Результаты: 128 В анализ были включены систематические обзоры. Средняя распространенность перинатальной депрессии, дородовой депрессии и послеродовой депрессии 26.3%

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… Funding This research was part of a PhD (full scholarship) at University of Manchester, which was funded by the Government of the Sultanate of Oman (Ministry of Higher Education). …

The salivary proteome in relation to oral mucositis in autologous hematopoietic stem cell transplantation recipients: a labelled and label-free proteomics approach.

BACKGROUND: Oral mucositis is a frequently seen complication in the first weeks after hematopoietic stem cell transplantation recipients which can severely affects patients quality of life. In this study, a labelled and label-free proteomics approach were used to identify differences between the salivary proteomes of autologous hematopoietic stem cell transplantation (ASCT) recipients developing ulcerative oral mucositis (ULC-OM; WHO score ≥ 2) or not (NON-OM). METHODS: In the TMT-labelled analysis we pooled saliva samples from 5 ULC-OM patients at each of 5 timepoints: baseline, 1, 2, 3 week

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… Oman Med J. 2012;27(5):348–357. doi: 10.5001/omj.2012.90. 40. Paladini RD, Takahashi K, Bravo NS, Coulombe PA. Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16. …

Exploring Healthcare Continuity in Pediatric-Onset Multiple Sclerosis in the United States.

OBJECTIVE: Little is known about shifting from pediatric to adult-focused multiple sclerosis (MS) care. This study aims to explore transition of care and follow-up in the US pediatric-onset MS (POMS) population. METHODS: Surveys were distributed to 10 sites in the US Network of Pediatric MS Centers (US NPMSC) about transition-of-care practices. A cohort of POMS/clinically isolated syndrome (CIS) at 12 US NPMSC sites was analyzed. The primary comparison was between < 18 and ≥ 18-years of age. The primary outcome was 1- and 2-year lapse in last follow-up visit, measured from last recorded datab

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… Al Kalbani , “ Implications of Language Barriers for Healthcare: A Systematic Review ,” Oman Medical Journal 35 , no. 2 ( 2020 ): e122 . 32411417 10.5001/omj.2020.40 PMC7201401 45 E. Wilson , D. Howard , D. Daniel , L. Taylor , M. P. Gorman , and L. A. …

Role of Chimeric Antigen Receptor T-Cells in the Evolving Therapeutic Landscape of Multiple Myeloma: A Literature Review.

Multiple myeloma (MM) is a quotidian malignant disorder of plasma cells. It is hallmarked by the uncontrolled growth of bone marrow plasma cells, leading to multiorgan dysfunction. Despite ongoing advancements in remedies, including chemotherapy, radiotherapy, immunomodulatory drugs, stem cell transplantations, and countless other lines of treatment, the management of MM remains a challenge. Recent studies indicate promising outcomes with chimeric antigen receptor T-cell (CAR-T) therapy, especially in patients who have previously undergone other treatments. This literature review aims to explo

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… Table 1 Number of cases and deaths of multiple myeloma (MM) within the Gulf Cooperation Council (GCC) in 2022 Table credit: [ 14 ] Country | Bahrain | Kuwait | KSA | UAE | Oman Number of cases | 15 | 65 | 295 | 69 | 61 Number of deaths | 12 | 44 | 229 | 37 | 47 Pathophysiology of MM The development …