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Abstracts of the 28th Annual San Antonio Breast Cancer Symposium, December 8-11, 2005, San Antonio, Texas, USA.

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… Indiana University Cancer Center, Indianapolis, IN; Dana Farber Cancer Institute; Pudget Sound Oncology Consortium; Memorial Sloan Kettering Cancer Center; Rush University Medical Center; Mayo Clinic; Vancouver Cancer Center; Johns Hopkins Oncology Center Purpose: This randomized phase III trial compared …

Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic.

Reduction-oxidation factor 1-apurinic/apyrimidinic endonuclease (Ref-1/APE1) is a critical node in tumor cells, both as a redox regulator of transcription factor activation and as part of the DNA damage response. As a redox signaling protein, Ref-1/APE1 enhances the transcriptional activity of STAT3, HIF-1α, nuclear factor kappa B, and other transcription factors to promote growth, migration, and survival in tumor cells as well as inflammation and angiogenesis in the tumor microenvironment. Ref-1/APE1 is activated in a variety of cancers, including prostate, colon, pancreatic, ovarian, lung an

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… Kelley has licensed E3330 (APX3330) through Indiana University Research and Technology Corporation to Apexian Pharmaceuticals. Apexian Pharmaceuticals had neither control nor oversight of the studies or the study design, results or interpretation, or presentation of the data in this manuscript. …

Selected Abstracts from the 12th Annual Meeting of the Clinical Immunology Society: 2021 Virtual Annual Meeting: Immune Deficiency and Dysregulation North American Conference.

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… Cecilia Poli, MD, PhD 14 , David Murdock, MD 7 , Tiphanie Vogel, M.D, Ph.D. 15 1 Resident/Baylor College of Medicine 2 Division of Rheumatology, Department of Pediatrics Associate Professor/Baylor College of Medicine/Texas Children's Hospital 3 Division of Rheumatology, Department of Pediatrics/Indiana … 10 Human Genome Sequencing Center Postdoctoral Associate/Baylor College of Medicine 11 Human Genome Sequencing Center Assistant Professor/Baylor College of Medicine 12 Undiagnosed Disease Network/Undiagnosed Disease Network 13 Division of Rheumatology, Department of Pediatrics Associate Professor/Indiana …

Demographic, epidemiological, and health transitions: are they relevant to population health patterns in Africa?

BackgroundStudies of trends in population changes and epidemiological profiles in the developing world have overwhelmingly relied upon the concepts of demographic, epidemiological, and health transitions, even though their usefulness in describing and understanding population and health trends in developing countries has been repeatedly called into question. The issue is particularly relevant for the study of population health patterns in Africa and sub-Saharan Africa, as the history and experience there differs substantially from that of Western Europe and North America, for which these conce

Выдержка гемпта (Extractum Cannabis) в деле " Лечение кишечных расстройств и диспепсии: исторические сведения из Барселоны, Испания " .

В этом исследовании изучается траектория интереса и использования экстракта каннабиса (выдержка канабиса сативы L.) для симптоматического лечения легких желудочно-кишечных расстройств и диспепсии в Барселоне XIX и начала XX века (Каталония, Испания) 1939, на основе обзора первичных источников. Цель настоящего документа заключается в том, чтобы представить исторический фармацевтический и прикладный обзор использования гематома (Cannabis L.) в медицинских целях до его запрещения, способствуя тем самым его признанию в качестве медицинского продукта. Представленная информация свидетельствует об ис

2021 Scientific Session of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), Las Vegas, Nevada, 31 August–3 September 2021: Video Loops

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… Vincent Hospital; 2 Indiana Hernia Center. This video demonstrates a reinforced biologic augmented repair (or ReBAR) of both an inguinal hernia and incisional hernia with robotic assistance. …

2026 Приложение к резюме Международного конгресса

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СРП 2013

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31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one : National Harbor, MD, USA. 9-13 November 2016

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… Nordrhein-Westfalen, Germany; 8 University of Pittsburgh, Pittsburgh, PA, USA; 9 CHU Rennes, Service Hématologie Clinique and INSERM 0203, Unité d'Investigation Clinique, Rennes, Bretagne, France; 10 Centre Hospitalier Régional Universitaire de Lille, Lille, Nord-Pas-de-Calais, France; 11 Simon Cancer Center, Indiana …

Abstract

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Student Summer Research Awards - SSRAAbstracts of the SSRA September 2022 meeting, UCD School of Medicine.

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Antibodies to watch in 2026.

The Antibodies to Watch article series provides annual updates on commercial late-stage clinical development, regulatory review, and marketing approvals of antibody therapeutics. Since the first article was published in 2010, the late-stage pipeline has grown from 26 antibody therapeutics to over 200, while during the same time numerous molecules in late-stage studies either transitioned to regulatory review and were approved or were terminated. In this installment of the series, we recap first marketing approvals granted to 19 antibody therapeutics in 2025, discuss 26 molecules currently in r

CAR-T cell therapy for cancer: current challenges and future directions.

Chimeric antigen receptor T (CAR-T) cell therapies have transformed the treatment of relapsed/refractory (R/R) B-cell malignancies and multiple myeloma by redirecting activated T cells to CD19- or BCMA-expressing tumor cells. However, this approach has yet to be approved for acute myeloid leukemia (AML), the most common acute leukemia in adults and the elderly. Simultaneously, CAR-T cell therapies continue to face significant challenges in the treatment of solid tumors. The primary challenge in developing CAR-T cell therapies for AML is the absence of an ideal target antigen that is both effec

Обязательный экзамен по патологии: лишний или необходимый?

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ISEV2025 Резюме книги.

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… function: implications for glaucoma pathogenesis Elie Beit‐Yannai 1 , Valeria Feinshtein 1 , Boris Knyazer 1 , Sofia Schreiber‐Avissar 1 , Padmanabhan Pattabiraman 2 , Christina Ferrara 2 , Isana Veksler‐Lublinsky 1 1 Ben‐Gurion University of the Negev, Be'er Sheva, Israel; 2 Ophthalmology Department, Indiana … University, Indianapolis, Indiana, USA Introduction : Primary open‐angle glaucoma (POAG) is a leading cause of irreversible blindness, characterized by progressive optic neuropathy often associated with elevated intraocular pressure (IOP). …

33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018) : Washington, D.C., USA. 7-11 November 2018.

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Abstracts from the ISSAID 2021 Periodic Congress : Virtual. May - Dec 2021

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… Goldbach-Mansky 1 1 Translational Autoinflammatory Diseases Section; 2 BCBB, NIAID, NIH; 3 NCI, NIH; 4 DLM, NIH; 5 CSI; 6 NCBR, NIAID, NIH, Bethesda; 7 Indiana University School of Medicine, Indianapolis; 8 Lurie Children’s Hospital, Chicago; 9 University of North Carolina School of Medicine, Chapel …

Increased Indoleamine 2, 3-Dioxygenase expression modulates Th1/Th17/Th22 and Treg pathway in humans with Helicobacter Pylori-Infected gastric mucosa.

Introduction and purposeIndoleamine 2, 3- dioxygenase (IDO) plays an importantrole in immunosuppressive pathway, as inhibits responsesof T cells and promotes immune tolerance. Host responsetoHelicobacter pylori (H. pylori) is involved in the infection persistenceand it is also associatedwith different clinical outcomes. The aim of this study was to investigate the role of IDO in H. pylori-infected patients with gastritis diseases and peptic ulcer diseases (PUD) through the assessment of the relationship among IDO protein expression and the numbers of T helper (Th)-1, Th17, Th22, and T regulato

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… Goggins, Transplant Immunology, IU Health, Indianapolis, Indiana, UNITED STATES| Aim: Single antigen bead (SAB) assays are used to detect and measure the strength of HLA Ab. …

Премии победителей и резюме 32nd Ежегодный симпозиум Общества протеинов; Бостон, ОЭТ, июль 9-12, 2018.

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… Contributions of Conformational Changes in Proteins Upon Ligand Binding Somnath Mukherjee 1 , Dionne Griffin 2 , James Horn 2 , Shahir Rizk 3 , Malgorzata Nocula‐Lugowska 1 , Anthony Kossiakoff 1 1 University of Chicago (Chicago, United States); 2 Northern Illinois University (DeKalb, United States); 3 Indiana …

Четвертое Международное совещание ИСЕВ, ISEV2015.

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