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Increased resistance to penicillin of pneumococci isolated from man.

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Molecular basis for several drug-induced nephropathies.

A recent clinical advance has been the discovery that many drug-induced hepatic diseases result from the metabolic activation of chemically stable drugs to potent alkylating agents by the liver. In addition to the liver, however, the kidney also contains active enzyme systems capable of metabolically activating drugs and other chemicals. For this reason a systematic investigation of the possible role of metabolic activation in the pathogenesis of several drug-induced renal diseases has been undertaken. These laboratory results are reviewed in the light of the clinical spectrum of the renal inj

Use of antibiotics in obstetric practice.

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Four cases of rickettsial endocarditis.

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Broad-spectrum penicillins in enteric infections of children.

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Meningitis caused by Streptococcus in adults.

Meningitis caused by Streptococcus is uncommon in adults. Otitis media, mastoiditis, sinusitis, or trauma has antedated most cases reported in the past. Data on 10 recent cases suggest changes in the current pathogenesis of streptococcal meningitis in adults and emphasize the importance of accurate streptococcal speciation. Endocarditis was present in five cases; trauma played a role in two others. Brain abscess, corticosteroids, alcoholic cirrhosis, and peritonitis secondary to chronic peritoneal dialysis were etiologic factors in five patients. Otitis media, mastoiditis, and sinusitis were c

Current status of the treatment of syphilis.

Penicillin remains the treatment of choice for syphilis, with sustained low blood levels curing virtually all patients having early syphilis and halting disease progression in most patients with symptomatic syphilis. Tetracycline, erythromycin or cephalothin yields similar cure rates for patients with early syphilis who are allergic to penicillin. The efficacy of non-penicillin regimens for the treatment of late syphilis is uncertain. Results of Venereal Disease Research Laboratory (VDRL) or other reagin tests should become negative or remain at very low titer following adequate therapy, altho

Urinary tract infections following transurethral prostatectomy: with special reference to the use of antimicrobials.

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Diagnosis and treatment of syphilis.

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Acute interstitial nephritis - a reappraisal and update.

Acute interstitial nephritis (AIN) is an under recognized and under diagnosed cause of acute kidney injury (AKI). It is estimated to account for 15 - 20% of cases of AKI; it is the reported diagnosis in 2.8% of all kidney biopsies, and 13.5% of biopsies done specifically for acute renal failure. Considerable evidence implicates antigen initiated cell-mediated injury in the pathogenesis of AIN. Drugs account for 70% of all cases, with over 150 different agents incriminated. The remaining cases are due to infections, autoimmune diseases, and rarely idiopathic. The central component of renal inju

Совпадение в полном тексте источника
… antibiotics Incidence > 50 cases reported Methicillin, rifampin, ciprofloxacin Incidence < 30 cases reported Acyclovir, amoxicillin, ampicillin, atazanivir, carbenicillin, cefazolin, cefaclor, cefamandole, cefotaxime, cefotetan, cefoperazone, cefoxitin, ceftriaxone, cephalothin, cephalexin, cephradine, cephaloridine … antibiotics | Incidence > 50 cases reported Methicillin, rifampin, ciprofloxacin Incidence < 30 cases reported Acyclovir, amoxicillin, ampicillin, atazanivir, carbenicillin, cefazolin, cefaclor, cefamandole, cefotaxime, cefotetan, cefoperazone, cefoxitin, ceftriaxone, cephalothin, cephalexin, cephradine, cephaloridine …

C

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Diseases of the Nervous System

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ECC-4 Abstracts

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