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Child Perceptions Questionnaire in Croatia: Two Domains for Measuring Oral Health.

OBJECTIVE: To perform cross-cultural adaptation and to test psychometric properties of the 8-item CPQ in 11-14 year-olds: stepwise-regression (RSF:8) and item-impact (ISF:8) short-forms. MATERIALS AND METHODS: The sample included 237 orthodontic patients aged 11-14 at two University Dental Clinics in Croatia. Structural and construct validity, reliability and responsiveness were assessed. Intraoral examination included an assessment of dental caries and malocclusion severity. RESULTS: Two domains instead of originally suggested four are more appropriate for the assessment of oral health-rela…

HPV-driven oropharyngeal squamous cell cancer in Croatia - Demography and survival.

OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Main HNSCC risk factors are tobacco, alcohol, and high-risk human papillomavirus (HPV). HPV+ oropharyngeal squamous cell cancer (OPSCC) usually have different etiology, increasing incidence and often show an improved survival when compared to HPV-negative cases. The objective of the current study was to retrospectively examine the influence of HPV on the survival of OPSCC patients in a non-Western population setting. MATERIALS AND METHODS: We determined the presence of HPV DNA and/or RNA i

Mosquito survey during West Nile virus outbreak 2012 in northeast Croatia.

During the August and September 2012, seven human cases of the West Nile neuro-invasive disease were reported in Croatia. Medical entomology research on a potential vectors during the outbreak was supported by the Ministry of Health. A mosquito survey has been done in 64 sites in three eastern Croatian counties (Osijek-Baranja County, Vukovar-Srijem county and in Brod-Posavina county). Dry ice baited CDC traps were used for mosquito sampling in a period from the 10th to 25th September 2012. A total of 1785 mosquitoes were collected and 5 species were determined. The most numerous species were …

Fibrous dysplasia in a 120,000+ year old Neandertal from Krapina, Croatia.

We describe the first definitive case of a fibrous dysplastic neoplasm in a Neandertal rib (120.71) from the site of Krapina in present-day Croatia. The tumor predates other evidence for these kinds of tumor by well over 100,000 years. Tumors of any sort are a rare occurrence in recent archaeological periods or in living primates, but especially in the human fossil record. Several studies have surveyed bone diseases in past human populations and living primates and fibrous dysplasias occur in a low incidence. Within the class of bone tumors of the rib, fibrous dysplasia is present in living hu…

Epidemiologic data of adult native biopsy-proven renal diseases in Croatia.

PURPOSE: There is a paucity of epidemiological data on biopsy-proven renal disease in Croatia. The purpose of this report is a review of clinical and histological data, over a period of 15 years, from the single biggest adult native renal biopsy center in Croatia. METHODS: This report includes data from 922 adult native renal biopsies in patients referred from the whole country and performed in our center from 1996 till February 2012. Data on age, gender, serum creatinine, urine sediment, 24-h proteinuria, clinical syndrome and histological diagnosis were collected and analyzed retrospectivel…

The MECP2 gene mutation screening in Rett syndrome patients from Croatia.

Rett syndrome (RTT) is an X-linked dominant neurodevelopmental disorder almost exclusively affecting females and is usually sporadic. Mutati … e cases should be further analyzed for gross rearrangements. This is the first study of its kind in Croatia and it enabled us to give the patients an early confirmation of RTT diagnosis.

Epidemiology of monosymptomatic optic neuritis in Rijeka County, Croatia: meteorological aspects.

In order to analyze the meteorological factors possibly influencing the monosymptomatic optic neuritis in Rijeka County, northwestern part of Croatia, retrospective analysis of all cases diagnosed in Rijeka County in period from 1977 to 2001, was done. Meteorological data on monthly and yearly temperature, humidity, insolation in Rijeka County were collected from Croatian Meteorological and Hydrological Service. In the observed period there were 173 cases of monosymptomatic optic neuritis, female/male ratio was 1.66, and overall incidence was 2.18/100,000 inhabitants. There was no correlation …

Prenatal diagnosis of congenital adrenal hyperplasia (21-hydroxylase deficiency) in Croatia.

We report on the prenatal diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase in 20 at-risk pregnancies (16 salt-wasting and 4 simple virilizing families). We have diagnosed 3 affected fetuses (2 males and 1 female), 3 healthy homozygotes (2 males and 1 female), and 14 healthy heterozygotes (7 females and 7 males). These data were collected over 4 years. In 16 fetuses, the diagnosis was made with measurements of 17-hydroxyprogesterone (17-OHP) and delta-4-androstenedione (delta) in amniotic fluid (AF), human leukocyte antigen (HLA) typing of amniotic cells, as well as karyotypes

A Ten Year Overview of Adrenal Vein Sampling in Croatia: Insights and Outcomes.

BACKGROUND: Adrenal vein sampling (AVS) is the gold standard for subtype differentiation in primary aldosteronism (PA), yet it remains technically demanding and resource intensive. However, data on long-term performance, learning curves, and concordance with imaging in real-world clinical practice are limited. METHODS: We conducted a retrospective single-centre study including patients with PA who underwent AVS between January 2016 and June 2025. AVS was performed under continuous adrenocorticotropic hormone stimulation using a sequential sampling protocol. Procedural success, learning curve,

Therapy changes in the treatment of subglottic laryngitis: A 30-year experience in Croatia.

BACKGROUND: Croup (viral laryngotracheitis, also referred to in some settings as subglottic laryngitis) can cause acute upper-airway obstruction and requires prompt management to prevent respiratory compromise. This study evaluated long-term changes in reported croup management in Croatia. METHODS: Questionnaires were distributed to pediatricians and otolaryngologists in multiple Croatian hospitals in 1993, 2003, 2013, and 2023. A standardized clinical vignette of a 2-year-old child with mild-to-moderate croup was used for the core longitudinal comparisons. Categorical variables are reported …

Occurrence of microplastics in bottled water from Croatia: a Raman spectroscopy approach.

The occurrence of microplastics (MPs) in bottled water is still largely unexplored in Croatia. This study fills this gap by analysing six water brands available on the Croatian market, all bottled in either virgin or recycled polyethylene terephthalate (PET). In order to analyse microplastics down to a size of 1 µm, the water from the purchased bottles was filtered with silicon filters with a pore size of 1 µm and then micro-Raman spectroscopy was performed. A significant reduction in analysis time was achieved by using a randomly selected filter area of 12.05 mm2 instead of the conventional 1…

Dental profiling in the archaeological sample of the Illyrian population in Southern Dalmatia, Croatia.

Background: Dental profiling is the process of analyzing teeth to identify a victim or skeletal remains when no antemortem data are available. Using dental profiling techniques, we can determine the age, sex, and population of the individual and gather data about their socio-economic status, personal habits, oral and systemic health, occupation, nutrition, family relationships, and psychological characteristics. Aims: The research aims to gain insights into the diet, health, socio-economic status, and demography of the Late Iron Age inhabitants of Illyrian origin who lived on the Croatian isla…

Prevalence of Overweight and Obesity among Primary School Students in Split, Croatia.

The rising prevalence of obesity among children and adolescents is a global public health concern, significantly contributing to noncommunicable chronic diseases such as cardiovascular disease, diabetes and cancer. In Croatia, obesity rates are alarmingly high, affecting both children and adults. Data from the Institute of the Public Health of Split-Dalmatian County were analyzed to identify trends in body mass index (BMI) among primary school students in Split, Croatia and possible connection with sports participation and parental education levels. A longitudinal analysis of students was cond…

Возрождение нейроинвазивных флавивирусов в Хорватии во время сезона трансмиссии 2022 года.

(Возрождение) новых арбовирусов, таких, как вирус энцефалита (ТБЭВ), вирус Западного Нила (ВНН) и вирус Усуту (УССВ), постоянно увеличивается. Мы проанализировали эпидемиологические характеристики инфекций флавируса у людей, сторожевых животных и комаров, обнаруженных в 2022 году в Хорватии. В период с апреля по ноябрь 2022 года 110 госпитализированных пациентов с нейроинвазивными заболеваниями (НИД) были проверены на наличие арбовирусов. RT-qPCR использовался для обнаружения TBEV, WNV и UUV RNA. Для обнаружения ароматических антител использовались тесты ELISA и нейтрализации вируса. Инфекция

Совпадение в аннотации оригинала
(Re-)emerging arboviruses, such as tick-borne encephalitis virus (TBEV), West Nile virus (WNV), and Usutu virus (USUV), are continuously increasing in incidence. We analyzed the epidemiological characteristics of flavivirus infections in humans, sentinel animals, and mosquitoes detected in the 2022 transmission season in Croatia. From April to November 2022,…

Current Status of Vector-Borne Diseases in Croatia: Challenges and Future Prospects.

Different vector-borne pathogens are present or have (re-)emerged in Croatia. Flaviviruses tick-borne encephalitis (TBEV), West Nile (WNV), and Usutu (USUV) are widely distributed in continental regions, while Toscana virus (TOSV) and sandfly fever viruses are detected at the Croatian littoral. Recently, sporadic clinical cases of Tahyna orthobunyavirus (TAHV) and Bhanja bandavirus infection and seropositive individuals have been reported in continental Croatia. Acute infections and serologic evidence of WNV, TBEV, USUV, and TAHV were also confirmed in sentinel animals and vectors. Autochthono…

Epidemiology of 10-year paediatric renal biopsies in the region of southern Croatia.

BACKGROUND: Information about renal diseases in children is available from national registries of renal biopsies. Aim of the study was to compare the clinical presentation of glomerular diseases and tubulointerstitial space diseases with pathohistological diagnosis of indicated renal biopsies from pediatric population in the Croatian region of Dalmatia. METHODS: Out of 231 pediatric patients with suspected glomerular and tubulointerstitial diseases, 54 underwent ultrasound-guided renal biopsy at University Hospital of Split. Kidney allograft biopsy, and re-biopsy were excluded. The biopsy sec…

Antibiotic Administration Along with Endodontic Therapy in the Republic of Croatia: a Pilot Study.

OBJECTIVE: To evaluate the type and the frequency of antibiotic prescribing along with endodontic therapy in Croatia. The aim is, also, to assess the attitudes of Croatian doctors towards endodontic treatment of patients at risk of developing bacterial endocarditis. MATERIAL AND METHODS: Data were collected by a survey questionnaire. RESULTS: 8.4% of the examined practitioners stated that they prescribe antibiotics often, and 91.6% of them stated that they prescribed them never/ very rarely/rarely. Most of them (41%) prescribe antibiotics once or twice a month, 32.5% once or twice in several…

Epidemiology of colistin-resistant, carbapenemase-producing Enterobacteriaceae and Acinetobacter baumannii in Croatia.

Colistin is a last-resort antibiotic for the treatment of infections caused by multidrug and carbapenem-resistant Gram-negative bacteria. Colistin resistance has been emerging and multiple outbreaks have been reported in Europe and elsewhere. It has been most frequently reported in carbapenem-resistant K. pneumoniae. In this study, 24 multidrug and colistin-resistant clinical isolates (14 K. pneumoniae, one E. aerogenes, one E. cloacae, and eight A. baumannii) were collected from four hospitals in Croatia from 2013 to 2018, in order to analyse the molecular epidemiology and mechanisms of antib…

Clinicopathological Characteristics of BRAF V600E Mutated Melanomas in the Dalmatian Region of Croatia.

A high proportion of cutaneous melanomas harbor activating mutations of the BRAF or NRAS genes, which are components of mitogen-activated protein kinase (MAPK) signal transduction pathway. The importance of BRAF V600E mutation in melanoma is not only related to the possibility of the administration of the targeted therapy, but also to the fact that BRAF V600E mutated melanomas have distinct clinicopathological features. We investigated the clinicopathological features of 80 primary skin melanomas with known BRAF V600E mutation status excised in the Dalmatian region of Croatia, with comparison …