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Публикации на разных языках · PubMed, Europe PMC и данные издателей через Crossref · 396 с найденным полным текстом
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Minimally Invasive Pedicle Screw Fixation Combined with Percutaneous Kyphoplasty Under O-Arm Navigation for the Treatment of Metastatic Spinal Tumors with Posterior Wall Destruction.

ObjectiveTo evaluate the safety and efficacy of O-arm-guided minimally invasive pedicle screw fixation combined with percutaneous kyphoplasty for metastatic spinal tumors with posterior wall destruction.MethodsPatients who underwent minimally invasive pedicle screw fixation combined with percutaneous kyphoplasty for pathological vertebral fractures with posterior wall defects from January 2015 to December 2017 were followed up for 1 year. Visual analogue scale (VAS), SF-36 scores, middle vertebral height, posterior vertebral height, and the accuracy of pedicle screws were assessed preoperative

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… At present, the two most popular methods of bone cement enhancement are vertebroplasty and kyphoplasty. The mechanism of pain relief is still controversial. Restoring spinal stability may be the main reason for pain relief. … Minimally invasive pedicle screw fixation combined with percutaneous vertebroplasty for preventing secondary fracture after vertebroplasty. J Orthop Surg Res, 2015, 10: 31. 29. Fuentes S, Blondel B, Metellus P, Gaudart J, Adetchessi T, Dufour H. …

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PMID 32578396Открыть статью

Improving functional outcome and quality of life for patients with metastatic lesion of acetabulum undergoing cement augmentation.

There is an increased enthusiasm in treating osteolytic metastatic acetabulum via injecting polymethyl-methacrylate (PMMA) as a bone filler to provide pain relief and potential structural support. The aim of this respective study is to determine the function and quality of life improvement after cement acetabuloplasty.Thirty two patients underwent acetabular cement augmentation between May 2014 and March 2018 were respectively reviewed. Isolated percutaneous acetabuloplasty (PA) was performed in 15 patients (group A) while radiofrequency ablation with PA (RFA-PA) in 12 patients (group B). Toge

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… In contrast, Orgera et al [ 24 ] performed a randomized controlled trial of 36 consecutive patients with spinal osteolytic lesions secondary to multiple myeloma, reported similar pain scores post procedure in both vertebroplasty alone and combined RFA and vertebroplasty groups (mean VAS scores at baseline … Cemented reconstruction of acetabular ceiling using the vertebroplasty set in treatment of metastatic lesions. Ortop Traumatol Rehabil 2014;16:129–37. [19] Moser TP, Onate M, Achour K, et al. …

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PMID 31490390Открыть статью

Risk Factors for Poor Outcome after Palliative Surgery for Metastatic Spinal Tumors.

Palliative surgery is performed to improve the quality of life of patients with spinal metastases. However, it is sometimes difficult to achieve the expected results because the patient's condition, and risk factors related to poor outcomes have not been well elucidated. This study aimed to evaluate the functional outcomes and investigate the risk factors for poor outcomes after palliative surgery for spinal metastasis. We retrospectively reviewed the records of 117 consecutive patients who underwent palliative surgery for spinal metastases. Neurological and ambulatory statuses were evaluated

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… SINS, Spinal Instability Neoplastic Score; ASA-PS, American Society of Anesthesiologists Physical Status; VP, vertebroplasty; BKP, balloon kyphoplasty. … Decompression between T11 to L1, T12 vertebroplasty, and percutaneous fixation from T10 to L2 were performed, and radiation therapy (30 Gy/10 Fr) was also performed after surgery ( Figure 1 e,f). …

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PMID 37240548Открыть статью

Short-term assessment of functional outcomes and quality of life after thoracic and lumbar spinal metastasis surgery.

BackgroundBecause of improvements in initial tumor identification and treatment, as well as longer life expectancies, more people are receiving diagnoses for spinal metastases.ObjectiveThe aim of this study was to assess early functional outcomes and quality of life (QOL) after surgical management of patients with spinal metastases.Patients and methodsIn this prospective cohort study, a total of 33 patients with thoracic and lumbar spine metastases who underwent surgical management between November 2021 and August 2023 were followed up for 1 year or until death. Oswestry Disability Index and t

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… Anterior reconstruction was performed in 13 (39.3%) patients, with Pyramesh in 2 (6%) patients and with open transpedicular vertebroplasty in 11 (33.3%) patients, whereas posterior fixation was only performed in 20 (60.6%) patients [ Figure 1 ]. … Cement leakage into the canal occurred in 2 (6.1%) patients, one with percutaneous fixation and the other with open vertebroplasty and fixation, without neurological damage. …

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PMID 39483824Открыть статью

Innovative Spine Implants for Improved Augmentation and Stability in Neoplastic Vertebral Compression Fracture.

Background and objectives: Tumor-related vertebral compression fractures often result in severe back pain as well as progressive neurologic impairment and additional morbidities. The fixation of these fractures is essential to obtain good pain relief and to improve the patients' quality of life. Thus far, several spine implants have been developed and studied. The aims of this review were to describe the implants and the techniques proposed to treat cancer-related vertebral compression fractures and to compile their safety and efficacy results. Materials and Methods: A systematic MEDLINE/PubMe

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… Percutaneous vertebroplasty (PVP) is now considered as an effective option to stabilize the fracture and provide good pain relief in addition or not with radiation therapy [ 15 ]. … Percutaneous vertebroplasty. Semin. Muscol. Radiol. 1997;1:285–295. doi: 10.1055/s-2008-1080150. 16. Mansoorinasab M., Abdolhoseinpour H. A review and update of vertebral fractures due to metastatic tumors of various sites to the spine: Percutaneous vertebroplasty. Interv. Med. Appl. …

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PMID 31370309Открыть статью

Unstable Pathologic Vertebral Fractures in Multiple Myeloma : Propensity Score Matched Cohort Study between Reconstructive Surgery with Adjuvant Radiotherapy and Radiotherapy Alone.

ObjectiveAlthough radiotherapy (RT) is recommended for multiple myeloma (MM) involving spine, the treatment of choice between reconstructive surgery with RT and RT alone for pathologic vertebral fractures (PVFs) associated with structural instability or neurologic compromises remains controversial. The purpose of this study was to evaluate the clinical efficacies of reconstructive surgery with adjuvant RT for treatment of MM with PVFs by comparing with matched cohorts treated with RT alone.MethodsTwenty-eight patients underwent reconstructive surgery followed by RT between 2008 and 2015 in a s

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… Seven patients treated with percutaneous vertebroplasty in group II were excluded after propensity score matching. Neurological and clinical outcomes The median survival time of all patients was 46.1 months. … In our study, seven patients treated with vertebroplasty in group II were not included after propensity score matching based on SINS. …

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PMID 34979628Открыть статью

Diagnosis and treatment of bone metastasis: comprehensive guideline of the Japanese Society of Medical Oncology, Japanese Orthopedic Association, Japanese Urological Association, and Japanese Society for Radiation Oncology.

Diagnosis and treatment of bone metastasis requires various types of measures, specialists and caregivers. To provide better diagnosis and treatment, a multidisciplinary team approach is required. The members of this multidisciplinary team include doctors of primary cancers, radiologists, pathologists, orthopaedists, radiotherapists, clinical oncologists, palliative caregivers, rehabilitation doctors, dentists, nurses, pharmacists, physical therapists, occupational therapists, medical social workers, etc. Medical evidence was extracted from published articles describing meta-analyses or random

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… Is vertebroplasty beneficial in bone metastasis? A. Vertebroplasty is beneficial for inoperable cases to sooner relieve pain on movement. (Weak, Evidence C) CQ 10. Is ablation is beneficial in bone metastasis? A. Ablation is beneficial to relieve pain. … (CQ 9) ‘It is weakly suggested that vertebroplasty is beneficial for inoperable cases to sooner relieve pain on movement’. …

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PMID 27843593Открыть статью

Combination radiofrequency ablation and vertebral cement augmentation for spinal metastatic tumors: A systematic review and meta-analysis of safety and treatment outcomes.

BACKGROUND: The treatment of spine metastases continues to pose a significant clinical challenge, requiring the integration of multiple therapeutic modalities to address the multifactorial aspects of this disease process. Radiofrequency ablation (RFA) and vertebral cement augmentation (VCA) are 2 less invasive modalities compared to open surgery that have emerged as promising strategies, offering the potential for both pain relief and preservation of vertebral stability. The utility of these approaches, however, remains uncertain and subject to ongoing investigation.This systematic review and

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… Data analysis Studies reporting changes in pain scores following RFA in combination with vertebroplasty were calculated according to a 0- to 10-point numeric rating scale (NRS). … The combination of radiofrequency ablation and vertebroplasty shows advantages over single vertebroplasty in treating vertebral neoplastic lesions. Skeletal Radiol. 2022;51(3):565–571. doi: 10.1007/s00256-021-03788-7. 41. Yildizhan S, Boyaci MG, Rakip U, Aslan A, Canbek I. …

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PMID 38510810Открыть статью

Initial non-weight-bearing therapy is important for preventing vertebral body collapse in elderly patients with clinical vertebral fractures.

PURPOSE: The aim of the present conventional observational study was to compare the clinical outcomes of initial non-weight-bearing therapy and conventional relative rest therapy among elderly patients with clinical vertebral fractures. METHODS: In total, 196 consecutive patients with clinical vertebral fractures (mean age: 78 years) who were hospitalized for treatment between January 1999 and March 2007 were analyzed. Initial non-weight-bearing therapy consisted of complete bed rest allowing rolling on the bed without any weight-bearing to the spine for 2 weeks, followed by rehabilitation we

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… Recently, two procedures designed to restore vertebral body height and function have been widely adopted: percutaneous vertebroplasty, in which cement is injected into the vertebral body to support the fractured bone; and kyphoplasty, a variant of vertebroplasty in which a balloon is inserted and inflated … Balancing science and informed choice in decisions about vertebroplasty. N Engl J Med. 2009;361(6):619–621. doi: 10.1056/NEJMe0905889. 7. Kallmes DF, Comstock BA, Heagerty PJ, et al. A randomized trial of vertebroplasty for osteoporotic spinal fractures. …

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PMID 22573944Открыть статью

Efficacy and safety of C-arm computed tomography-guided microwave ablation with percutaneous osteoplasty for flat bone metastases.

BACKGROUND: Flat bone metastases are common in patients with advanced cancers, often resulting in severe pain, limited mobility, and reduced quality of life (QOL). Traditional treatment options, such as radiotherapy or systemic therapies, often fail to provide sufficient pain relief or improve functional outcomes in these patients. Microwave ablation (MWA) offers advantages, such as shorter procedure times and larger ablation zones, while percutaneous osteoplasty (PO) enhances bone stability and prevents pathological fractures. Despite these benefits, the combination of these techniques for tr

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… : an in vivo study in humans Intervent Radiol 2009 32 491 498 10.1007/s00270-009-9509-7 19280257 13 Yang HL Sun ZY Wu GZ Chen KW Gu Y Qian ZL Do vertebroplasty and kyphoplasty have an antitumoral effect? … RJ Bendok BR Sato KT Liu JC Patel JD Rosen ST Combination treatment of vertebral metastases using image-guided percutaneous radiofrequency ablation and vertebroplasty: a case report Surg Neurol 2005 63 469 74; discussion 474 15883077 10.1016/j.surneu.2004.04.025 16 Pusceddu C Sotgia B Fele RM Ballicu …

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PMID 40130060Открыть статью

The use of interventional procedures for cancer pain. A brief review.

ContextPain is a common experience in people living with cancer. Concerns around opioid prescribing have seen a move toward a multi-modality management approach, which includes interventional pain procedures.PurposeIn this paper we discuss the interventional pain procedures used to treat cancer pain at two major tertiary centers in Australia.Methods and resultsThis expert review provides practical insights on cancer pain management from healthcare providers in different specialties. These insights can be used to guide the management of a wide range of cancer pain types.ConclusionsFurthermore,

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… Vertebroplasty Vertebroplasty involves the injection of artificial bone cement and an opacifier into the inter-trabecular marrow space of fractured vertebrae [ 37 ]. It is performed with imaging guidance under local anesthesia [ 37 , 38 ]. … In Australia, vertebroplasty is performed infrequently due to its invasive nature and lack of clear evidence of its benefit. …

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PMID 38607568Открыть статью

State-of-the-Art Management of Complications of Myeloma and Its Treatment.

Multiple myeloma is an incurable disease, although patient survival has increased with the availability of novel agents. Both multiple myeloma and its therapies often affect the renal, immune, skeletal, hematologic, and nervous systems. The resulting organ dysfunctions often impair the quality of life of affected patients, complicate and limit subsequent therapies, and may result in significant mortality. Research on the treatment of complications of multiple myeloma has been limited; hence, preventative and management strategies for patients with these complications are heterogeneous and ofte

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… More recently, patients with painful vertebral compression fractures can be treated with vertebroplasty or balloon kyphoplasty. Vertebroplasty involves injection of poly-methylmethacrylate bone cement in the vertebral body. … In addition to pain control, height restoration can be achieved with this procedure, and in some centers this procedure is preferred over vertebroplasty [ 53 , 54 ]. …

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PMID 20671999Открыть статью

The value of routine biopsy during percutaneous kyphoplasty for vertebral compression fractures.

ObjectivePercutaneous kyphoplasty (PKP) is now widely performed to treat VCF, which is usually caused by osteoporosis. Previous researches have reported unsuspected malignancies found by biopsy. However, the safety and cost-effective profiles of routine biopsy during PKP are unclear. The purpose of this study was to evaluate the feasibility of routine biopsy during PKP in treatment of VCF.MethodsNinety-three patients (September 2007-November 2010) undergoing PKP without biopsy were reviewed as the control group. One hundred and three consecutive patients (November 2010-September 2013) undergoi

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… Minimally invasive techniques such as percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP) were increasingly used in the treatment for chronic pain and disabilities caused by VCF in recent years, and proven as effective and safe methods [5] . … Muijs SP, Akkermans PA, van Erkel AR, Dijkstra SD (2009) The value of routinely performing a bone biopsy during percutaneous vertebroplasty in treatment of osteoporotic vertebral compression fractures. Spine (Phila Pa 1976) 34:2395–2399. 13. …

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PMID 25526360Открыть статью

Impact of Cytogenetic Abnormalities, Induction and Maintenance Regimens on Outcomes After High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma: A Decade-Long Real-World Experience.

BackgroundHigh-dose chemotherapy and autologous stem cell transplant (HDT-ASCT) has become a standard of care for transplant eligible newly diagnosed multiple myeloma (NDMM) patients. While cytogenetic abnormalities have been shown to affect outcomes after HDT-ASCT in clinical trials, these trials often exclude or underrepresent elderly patients with comorbidities and those belonging to ethnic minorities. We describe our institutional experience highlighting the impact of high-risk cytogenetic abnormalities (HRCAs) on outcomes after HDT-ASCT for NDMM patients.MethodsA total of 449 patients wit

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… Cement pulmonary embolism as a complication of percutaneous vertebroplasty in cancer patients. Cancer Imaging. 2018;18(1):5. doi: 10.1186/s40644-018-0138-8. 13. Choe DH, Marom EM, Ahrar K, Truong MT, Madewell JE. … Pulmonary embolism of polymethyl methacrylate during percutaneous vertebroplasty and kyphoplasty. AJR Am J Roentgenol. 2004;183(4):1097–1102. doi: 10.2214/ajr.183.4.1831097. 14. Patel Z, Sangani R, Lombard C. …

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PMID 38188477Открыть статью

Multifocal intraosseous hemangioma: A case report.

RationaleMultifocal intraosseous hemangioma, which affects multiple body parts, is rare. The selection of appropriate lesion sites for biopsy and effective treatment in multifocal intraosseous hemangioma is challenging. Here, we report a case of multifocal intraosseous hemangioma.Patient concernsA 49-year-old woman was admitted to our department with a chief complaint of aggravated lumber pain for 10 days.DiagnosesRadiographic imaging revealed lesions involving the bilateral ribs, lumbar vertebrae, ilium, pubis, and proximal femur. Open biopsy in the ilium established the pathological diagnosi

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… Currently, the main treatment options include surgery, intraarterial embolization, vertebroplasty, and radiotherapy. However, no consensus has been reached to date regarding the management of vertebral hemangiomas. … Mirovsky reported 4 patients who underwent preoperative transarterial embolization followed by laminectomy and vertebroplasty of the affected level and 2 patients who were treated with vertebroplasty alone. …

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PMID 30633188Открыть статью

Painful boney metastases.

Boney metastasis may lead to terrible suffering from debilitating pain. The most likely malignancies that spread to bone are prostate, breast, and lung. Painful osseous metastases are typically associated with multiple episodes of breakthrough pain which may occur with activities of daily living, weight bearing, lifting, coughing, and sneezing. Almost half of these breakthrough pain episodes are rapid in onset and short in duration and 44% of episodes are unpredictable. Treatment strategies include: analgesic approaches with "triple opioid therapy", bisphosphonates, chemotherapeutic agents, ho

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… Vertebroplasty Percutaneous vertebroplasty, first described in 1987, is a radiologically guided procedure in which percutaneous injection of polymethylmethacrylate, a surgical bone cement, is injected into a vertebra under imaging guidance [ 80 ]. … Lee and colleagues reported on 19 percutaneous vertebroplasty procedures performed mainly in breast, prostate, lung and renal cancers [ 81 ]. …

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PMID 23861996Открыть статью

Surgery of the tumors of the spine.

Spinal tumors encompass a heterogeneous group of primary and metastatic lesions requiring individualized management strategies based on tumor biology, patient prognosis, and mechanical stability. Decision-making frameworks, such as NOMS, SINS, and Tokuhashi score, provide structured guidance for selecting metastatic patients for surgery and defining individualized treatment strategies. En bloc resection remains the gold standard for selected primary malignant tumors, whereas separation surgery combined with stereotactic radiosurgery represents the cornerstone of modern metastatic spine disease

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… Cement augmentation techniques (vertebroplasty/kyphoplasty) Percutaneous vertebral augmentation techniques, including vertebroplasty and kyphoplasty, have become integral components in the management of spinal tumors, particularly in the palliative setting ( 55 , 56 , 57 ). … (A) Fourteen months after previous vertebroplasty, a percutaneous vertebroplasty of L2 was performed via a right transpedicular approach. (B) Intraoperative fluoroscopic image during cement injection. (C) Final sagittal radiographic image demonstrating adequate cement distribution. …

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PMID 42684947Открыть статью

Interleukin Concentrations in Bone Marrow Fluid and MRI Prognostic Findings in Osteoporotic Vertebral Fractures.

Objective We investigated the association between interleukin-6 (IL-6) and interleukin-8 (IL-8) concentrations in bone marrow fluid and osteoporotic vertebral fracture (OVF) prognosis to obtain insights that could improve the prediction of poor prognosis. Methods Patients with OVFs admitted consecutively to a single facility and who underwent balloon kyphoplasty were prospectively enrolled. Bone marrow fluid was collected during surgery, and IL-6 and IL-8 concentrations were measured. Independent experts blinded to patient details examined the preoperative magnetic resonance imaging (MRI) radi

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… Percutaneous vertebroplasty (PVP) is a treatment option for OVF but has been ruled out as the standard treatment [ 2 , 3 ]. PVP and balloon kyphoplasty (BKP) can reduce the quality of life of patients by limiting the target population for treatment [ 4 , 5 ]. … A randomized trial of vertebroplasty for osteoporotic spinal fractures. Kallmes DF, Comstock BA, Heagerty PJ, et al. N Engl J Med. 2009;361:569–579. doi: 10.1056/NEJMoa0900563. 3. A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. …

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PMID 41179017Открыть статью

Evaluating the Accuracy and Efficiency of Imaging Modalities in Guiding Ablation for Metastatic Spinal Column Tumors: A Systematic Review.

Background/objectivesSpinal metastases are a frequent and serious complication in cancer patients, often causing severe pain, instability, and neurological deficits. Thermal ablation techniques such as radiofrequency ablation (RFA), microwave ablation (MWA), and cryoablation (CA) have emerged as minimally invasive treatments. These techniques rely on precise imaging guidance to effectively target lesions while minimizing complications. This systematic review aims to compare the efficacy of different imaging modalities-computed tomography (CT), magnetic resonance imaging (MRI), fluoroscopy, and

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… The Combination of Radiofrequency Ablation and Vertebroplasty Shows Advantages over Single Vertebroplasty in Treating Vertebral Neoplastic Lesions Skelet. Radiol. 2022 51 565 571 10.1007/s00256-021-03788-7 34247255 64. Wang L. Lu M. Zhang X. Zhao Z. Li X. Liu T. Xu L. Yu S. … Percutaneous CT-Guided Microwave Ablation Combined with Pedicle Screw Fixation Followed by Vertebroplasty (MASFVA): Initial Experience of a Minimally Invasive Treatment of Vertebral Metastases with Extension to the Vertebral Pedicle Curr. …

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PMID 39682134Открыть статью

Sagittal and Frontal Plane Evaluation of the Whole Spine and Clinical Outcomes after Vertebral Fractures.

Although it is known that a change in any level of the spine alters biomechanics, there are not many studies to evaluate the spine as a whole in both sagittal and frontal planes. This prospective cohort study evaluates the morphology and mobility of the entire spine in patients with vertebral fractures. The Treatment Group consisted of 43 patients who underwent percutaneous balloon kyphoplasty or percutaneous balloon kyphoplasty plus fixation. The Control Group consisted of 39 healthy subjects. Spinal Mouse was used for the assessment of the curvatures and the mobility of the spine. Clinical o

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… Questionnaires Regarding VAS score, it is known that BKP and vertebroplasty offer instant and significant relief from pain and present better results in comparison with conservative treatment [ 5 , 10 ]. … New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures Spine 2001 26 14 1511 1515 10.1097/00007632-200107150-00002 2-s2.0-0035879089 11462078 6 Koller H. Acosta F. Hempfing A. …

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PMID 26635978Открыть статью