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Design and optimization of highly reliable cognitive non-orthogonal multiple access communication systems.

In this paper, we consider a coexisting network of cellular transmission and device-to-device (D2D) communication, in which BS wants to communicate with far user, meanwhile, a D2D source desires to transmit information to a D2D destination. However, due to heavy shadowing or severe path loss, their direct links are not available. To cope with this problem, a relay is employed to assist the involved transmission. For such a relay-assisted spectrum sharing network, two transmission schemes are designed, i.e., multiple access broadcast NOMA (M-NOMA) scheme and time division broadcast NOMA (T-NOMA…

Corporate communication as discursive decriminalization and symbolic compliance in transnational corruption criminal proceedings.

OBJECTIVE: The purpose of this study was to examine and to determine whether triplet pregnancies are associated with a significantly greater risk of adverse outcome than are twin pregnancies. METHODS: Maternal and perinatal outcomes were evaluated retrospectively in 41 sets of triplets and twin pregnancies that were matched for maternal age, parity, mode of delivery, preterm delivery, mode of conception, and antepartum complications. MAIN OUTCOME MEASURES: Perinatal outcome in triplet versus twin gestation. RESULTS: Triplets had a significantly lower mean average birth weight than in twin g

Potential molecular communication of blood and synovium through ligand-receptor interactions in osteoarthritis.

INTRODUCTION: Osteoarthritis (OA) is a common degenerative joint disease resulting from the breakdown of multiple joint tissues, remains a leading cause of disability with limited therapeutic options. Synovitis is one of the reasons of OA progression, while communication between blood and synovium during disease process is still unclear. METHODS: We used transcriptomic datasets from blood and synovium of healthy controls and OA patients to investigate potential molecular crosstalk between blood and synovium in OA pathogenesis through ligand-receptor pairs. RESULTS: Ligand-receptor pair analy…

Vesicular Communication in the Bone-Muscle Unit: Physiological Functions, Aging, and Therapeutic Potential.

Extracellular vesicles (EVs) have emerged as fundamental pillars of intercellular communication, acting as primary mediators of the bidirectional biochemical crosstalk within the integrated bone-muscle unit. This review provides a comprehensive synthesis of EV-mediated signaling across the bone-muscle axis, offering a side-by-side mapping of vesicular biogenesis, cargo composition, and functional roles in both tissues. Under physiological conditions, skeletal muscle- and bone-derived EVs orchestrate tissue homeostasis, adaptations to physical exercise, myogenesis, and bone remodeling by transf…

Disruption of major Ptchd1 isoforms causes autistic traits in social behavior and communication.

PTCHD1 is an X-linked three-exon gene associated with autism spectrum disorder (ASD) and/or intellectual disability (ID). Mice lacking Ptchd … Ptchd1Δexon3 mutants, both Ptchd1_a and Ptchd1_c were lost, along with dysregulation of social and communication behaviors, increased repetitive behavior, and motor and learning impairments. Our side-by-side analyses of Ptchd1Δexon2 and Ptchd1Δexon3 mice suggest a functional link between PTCHD1/Ptchd1 and ASD, demonstrating that loss-of-function mutations disr …

Preadmission, admission, and post-discharge factors associated with impaired communication after hemorrhagic stroke.

BACKGROUND: Many survivors of hemorrhagic stroke have impaired communication. We aimed to identify preadmission, admission, and post-discharge factors associated with self-reported impaired communication after hemorrhagic stroke. DESIGN: Patients with intracerebral or subarachnoid hemorrhage (ICH or SAH) admitted at an urban academic medical center were assessed 3-months post-bleed using the communication Quality of Life in Neurological Disorders (Neuro-QoL) short form inventory. Multivariate analysis was performed to evaluate the relationship between impaired communication (Neuro-QoL scaled …

BDNF-related brain-liver communication in metabolic syndrome: implications for anxiety and depression.

Metabolic syndrome is frequently accompanied by anxiety and depression, suggesting interactions between metabolic dysfunction and affective regulation. Brain-derived neurotrophic factor (BDNF) and its high-affinity receptor tropomyosin receptor kinase B (TrkB) are involved in energy balance, neuroplasticity, stress adaptation, and emotional processing, positioning BDNF-related signaling as a potential interface within brain-liver communication. Experimental evidence strongly supports central BDNF-TrkB signaling in the regulation of feeding and energy expenditure, while central BDNF-sensitive p…

Innovations in Deaf Health Care Communication: Systematic Review of Sign Language Recognition Systems.

BACKGROUND: Deaf individuals often face communication challenges when interacting with those who can hear. Within health care settings, these challenges may pose risks to their safety, potentially resulting in misdiagnoses, treatment errors, and decreased quality of care. OBJECTIVE: This study aims to systematically review the evidence on communication systems reported in the literature that use human-computer interaction techniques to support communication between deaf individuals who use sign language and hearing health professionals in health care settings. The review focuses on systems th…

ELAVL Proteins, miRNA Fate, and Extracellular RNA Communication in Brain Aging and Neurodegeneration.

Brain aging is accompanied by changes in RNA homeostasis, intercellular communication, and stress responses that increase vulnerability to neurodegenerative diseases. The neuronal protein HuD (ELAVL4) and the broadly expressed HuR (ELAVL1) regulate RNA stability, translation, localization, and selected microRNA (miRNA) activities. Recent studies further show that HuD can promote export of let-7a and miR-125b during differentiation of PC12 cells, whereas HuR can bind selected miRNAs and engage endosomal export or intracellular buffering mechanisms in other cellular contexts. These observations …

Доверие, информационная оценка и общение между людьми, живущими с множественным склерозом.

Справочная информация: Люди, страдающие множественным склерозом (МС), все чаще обращаются в Интернет за информацией о своем состоянии и лечении. Вместе с тем информация о состоянии здоровья в онлайновом режиме существенно варьируется по качеству, и пациенты часто не имеют грамотности в области электронного здравоохранения, необходимой для проведения различия между надежными и ненадежными источниками. Цель: В этом исследовании рассматривается вопрос о том, каким образом лица, имеющие НР в Соединенном Королевстве, стремятся получить, оценить и оценить качество онлайновой информации по вопросам з

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… The proliferation of disease-specific platforms, social media communities, and patient charity websites has reinforced this trend, and the COVID-19 pandemic accelerated the shift toward digitally mediated health information [ 13 ]. 1.1. … Education in patient-physician communication: How to improve effectiveness? Patient Educ. Couns. 2013 90 46 53 10.1016/j.pec.2012.09.005 23068910 9. Fowler F.J. Jr. Levin C.A. Sepucha K.R. …

Addressing HPV vaccine hesitancy and misinformation in India through public health communication strategies.

India witnessed a significant step forward in cervical cancer prevention and human papillomavirus (HPV) vaccine coverage with the rollout of … and COM-B theoretical framework, it proposes a culturally sensitive, evidence-based multifactorial communication strategy focused on raising awareness, building trust, countering misinformation, capacity building of healthcare providers, and enhancing opportunities for the adoption of HPV preventive behavior. The commentary highlights the need to actively enga …

Hijacking Host Communication: The Central Role of Extracellular Vesicles in Infectious Disease Pathogenesis.

Extracellular vesicles (EVs) have emerged as fundamental mediators of intercellular communication during infectious diseases, acting as vehicles for proteins, lipids, and nucleic acids that profoundly influence host-pathogen interactions. In recent years, accumulating evidence has revealed that pathogens from distinct biological kingdoms, including protozoan parasites, viruses, and bacteria, either release their own EVs or exploit host-derived EVs to manipulate immune responses, promote infection, and sustain chronic disease. This review provides a comprehensive and integrative overview of the…

Therapeutic Communication as Autobiographical Memory Scaffolding: Bridging Developmental Science and Psychiatric Nursing Practice.

OBJECTIVE: To introduce the developmental and cross-cultural science of autobiographical memory to psychiatric nursing and argue that therapeutic communication functions as autobiographical memory scaffolding. METHODS: This discussion article integrates three fields within the literature: elaborative reminiscing and autobiographical memory development (developmental psychology), overgeneral autobiographical memory (clinical psychology), and cultural variation in autobiographical recall (cross-cultural research). It applies the integration to psychiatric nursing assessment and intervention. R…

Earning Trust Before the Crisis: Health Literacy and Communication Readiness in Healthcare Systems.

Risk communication and community engagement are fundamental to healthcare preparedness, yet many systems still focus solely on communication during a public health emergency. At this point, trust may be fragile, misinformation may be circulating, and healthcare professionals may be asked to explain changing guidance without sufficient preparation or organizational support. This Perspective starts from the premise that communication and community engagement should begin before a crisis. We argue that messaging alone is insufficient to earn trust; healthcare systems must be transparent, accessib…

scACCorDiON: a clustering approach for explainable patient level cell-cell communication graph analysis.

MOTIVATION: Combining single-cell sequencing with ligand-receptor (LR) analysis paves the way for the characterization of cell communication events in complex tissues. In particular, directed weighted graphs naturally represent cell-cell communication events. However, current computational methods cannot yet analyze sample-specific cell-cell communication events, as measured in single-cell data produced in large patient cohorts. Cohort-based cell-cell communication analysis presents many challenges, such as the nonlinear nature of cell-cell communication and the high variability given by the p…

Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication.

Pancreatic alpha cells modulate beta cell function in a paracrine manner through the release of glucagon. However, the detailed molecular architecture underlying alpha-to-beta cell regulation remains poorly characterized. Here, we show that the glucagon-like peptide-1 receptor (GLP1R) is enriched as nanodomains on beta cell membranes that contact alpha cells, in keeping with increased single-molecule transcript expression. At low glucose, beta cells next to alpha cells directly sense micromolar glucagon release by pre-internalizing GLP1R. Pre-internalized GLP1R is associated with earlier beta

Oral hygiene habits are risk factors of oral cavity cancer: a short communication.

Poor oral hygiene is a well-established risk factor for oral cavity cancer. However, the specific association between oral hygiene practices and oral cancer risk remains unclear. This study aimed to investigate the relationship between oral hygiene habits and the risk of oral cavity cancer. A case-control study was conducted involving 231 participants: 94 oral cavity cancer patients (case group) and 137 controls with other head and neck cancers. Oral health status was assessed using the Revised Oral Assessment Guide - Jönköping (ROAG-J), and a structured questionnaire was used to collect data

Cayley-Purser secured communication and jackknife correlative classification for COVID patient data analysis.

Internet of Medical Things (IoMT) is a group of medical devices that connect the healthcare information technology to minimize the redundant hospital visit and healthcare system troubles. IoMT connect the patients to the doctor and transmit the medical data over the network. The spread of corona virus has put the people at high risk. Due to increasing number of cases and its stress on health professionals, IoMT technology is used in many healthcare centers. But, the security level and data classification accuracy was not improved by existing methods during the data communication. In order to s…

Asymmetry and Alignment: Physician Perspective on Patient-Based Evidence for Improving Health Communication.

We investigated the response of experienced amyotrophic lateral sclerosis physicians to patient-based evidence pertaining to health communication. Fifteen expert amyotrophic lateral sclerosis (ALS) physicians participated in an in-person focus group. Focusing on clinical feasibility and first-hand experience, participants discussed recommendations from people with ALS and caregivers for improving communication. Data were qualitatively analyzed using conventional content analysis. Findings demonstrated shared and differing perspectives, and communication challenges. Findings suggest a differenc…

Pharmacological modulation of directed network communication and neural hubs in action-effect integration.

BACKGROUND: Acting intentionally requires individuals to anticipate the effects of their actions. Recent work has revealed the neural oscill … and methylphenidate conditions. Electroencephalogram data were analyzed to investigate the directed communication in cortical networks underlying action effect integration. RESULTS: We show that an increase in catecholaminergic system activity alters the strength of directed communication in a cortical theta frequency network constituted by the insular cortex, …