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Chronic fatigue and minor psychiatric morbidity after viral meningitis: a controlled study.

OBJECTIVE: To test the hypotheses that patients exposed to viral meningitis would be at an increased risk of developing chronic fatigue syndrome and would have an excess of neurological symptoms and physical impairment. METHODS: Eighty three patients were followed up 6-24 months after viral meningitis and a postal questionnaire was used to compare outcome with 76 controls who had had non-enteroviral, non-CNS viral infections. RESULTS: For the 159 patients and controls the prevalence of chronic fatigue syndrome was 12.6%, a rate higher than previously reported from primary care attenders, sug…

Effect of vibration on antagonist muscle coactivation during progressive fatigue in humans.

1. Biceps femoris antagonist coactivation increases during progressive fatigue. Our purpose was to determine if the mechanism that increases coactivation during fatigue is susceptible to vibration. Vibration drives alpha-motoneurons via the Ia loop, producing force without descending motor drive, and thus uncoupling antagonist and agonist activation. Evidence that vibration increases coactivation disproportionately from its 'common drive' would suggest the possibility that some of the effects of fatigue are mediated through a segmental reflex loop. 2. Ten male subjects performed repeated maxim…

Public knowledge, attitudes, and beliefs about homeless people: evidence for compassion fatigue.

Media reports suggest that the public is becoming impatient with the homeless--that so-called "compassion fatigue" has gripped the nation. This characterization of public sentiment could have important policy consequences-- restrictive measures can be justified by growing public impatience, and progressive housing policies seem feasible within a hostile climate of opinion. But evidence to support the compassion fatigue notion is anecdotal. We examine the issue by tracking the results of public opinion polls and by reporting detailed evidence from a nationwide random-digit dial telephone survey…

Chronic fatigue syndrome associated with a psychotic state resulting in multiple murders.

A 28-year-old, ambitious, academically successful Asian man with a zeal for hard work develops infectious mononucleosis and its resultant lethargy and fatigue. He becomes depressed, then develops symptoms of mania before turning floridly psychotic. In his psychotic state he develops grandiose delusions about being the second son of God after Christ and takes it upon himself to rid the world of all evil by defeating the anti-Christ. He kills four people and seriously injures a fifth. He is arrested and found not guilty by reason of insanity. He remains a diagnostic puzzle for a long time before…

Сопоставление коксаки Б нейтрализации и информуационного ПЦР у пациентов, страдающих хронической усталостью.

В качестве агентов, связанных с хроническим синдромом усталости (КФС), неоднократно упоминались энтеровирусы Коксаки В. Цель этого исследования состояла в том, чтобы сравнить серологические доказательства наличия вируса Коксаки В, нейтрализирующего антитела, с тем, чтобы цепная реакция полимеразы (ПКР) выявила часть 5-футовой области генома энтеровируса (NTR). В ходе этого исследования использовались образцы сыворотки 100 пациентов, страдающих от хронической усталости, и 100 больных, страдающих от здоровых сопоставителей. В исследовательской группе КВПБ 42% пациентов были положительно восприня

Совпадение в аннотации оригинала
Coxsackie B enteroviruses have been implicated repeatedly as agents associated with chronic fatigue syndrome (CFS). The objective of this study was to compare the serological evidence for the presence of Coxsackie B virus neutralising antibody, with the polymerase chain reaction (PCR) detecting a portion of the 5' nontranslated region (NTR) of the enteroviru…

Chronic fatigue syndrome: have flawed assumptions been derived from treatment-based studies?

Chronic fatigue syndrome is a disabling disorder that has been studied primarily in clinical settings. In the absence of an adequate epidemiological database, cultural stereotypes have influenced the characterization of chronic fatigue syndrome as "the yuppie flu," similar to the 19th century characterization of neurasthenia as a disease of the affluent. The limited epidemiological data available and the overall medical-sociological literature call this assumption into question. Only a community "true" prevalence study that is unbiased by help seeking and access to health care can provide an a…

Epidemic neuromyasthenia and chronic fatigue syndrome: epidemiological importance of a cluster definition.

Outbreaks of illness variously identified by a number of terms, including epidemic neuromyasthenia, myalgic encephalomyelitis, Iceland disease, and atypical poliomyelitis, have been reported from many countries during the past 45 years. Since the first well-described outbreak occurring in 1934, > 60 outbreaks have been reported, but few of these have been described in considerable detail. These outbreaks are usually cited in historical reports of chronic fatigue syndrome (CFS) since each of these outbreaks appears to contain a number of cases meeting the current case definition of CFS. There h…

[Chronic fatigue syndrome--51 cases in the Jikei University School of Medicine].

Between April 1991 and August 1992, we diagnosed 51 cases of CFS who met definition of CFS designated by CDC, 1988. They are 41 female and 11 male, and 78% are women. At first visit, their ages are ranged from 16 to 64 years old, and approximately 45% is 20 to 30 years old. In periods of illness from onset, 39.2% of the patients are in period of 6 month to 1 year, 19.6% within 2 years, and 15.6% within 3 years, respectively. The sufferer who have symptoms of CFS over 10 years long are in 6 cases. Most of patients have already been examined by many other clinics and hospitals. They have been to

Chronic fatigue syndrome: I. Epstein-Barr virus immune response and molecular epidemiology.

Patients with chronic fatigue syndrome were compared to healthy seropositive control subjects in an open study and a case-control study analyzing spontaneous transformation rates of peripheral blood lymphocytes, EBV viral genome characteristics as determined by DNA restriction fragment polymorphisms, and antibody production by Western blot analysis. Thirty percent of patients versus 8% of control subjects underwent spontaneous transformation in the two studies. Viral genome patterns were overall similar to one another, with polymorphisms frequently present in BamHI B', K, H, and Y fragments. O…

Physiologic parameters and perceived exertion with local muscle fatigue in postpolio subjects.

Fifty postpolio patients, 34 with and 16 without complaints of progressive loss of muscle strength, and 41 control subjects were studied to compare physiologic measures of the fatiguing process and to determine whether there is a significant interaction between the rating of perceived exertion (RPE) and physiologic measures. Statistical analyses were by ANOVA and repeated-measures ANOVA. The RPE was obtained every 20 seconds during an isometric contraction of the quadriceps at 40% of maximal torque; median frequency (Fm) of the power spectrum of the surface electromyographic signal and neuromu

[Decreased reading speed and rapid fatigue as signs of disordered visual function].

Monocular and binocular reading curves of 20 patients (4 with cataract, 5 with glaucoma, 11 with maculopathy) were recorded by infrared ocul … hat measurement of reading speed is a valuable function test, and to the fact that in certain cases fatigue of an eye during reading is a new and measurable criterion of the degree of visual impairment.

Bilateral phrenic stimulation: a simple technique to assess diaphragmatic fatigue in humans.

Transdiaphragmatic pressure (Pdi) and the rate of relaxation of the diaphragm (tau) were measured at functional residual capacity (FRC) in six normal seated subjects during single-twitch stimulation of both phrenic nerves. The latter were stimulated supramaximally with needle electrodes with square-wave impulses of 0.1-ms duration at 1 Hz before and after diaphragmatic fatigue produced by resistive loaded breathing. Constancy of chest wall configuration was achieved by monitoring the diameter of the abdomen and the rib cage with a respiratory inductive plethysmograph system. During control the…

A new syndrome: thrombocytopathia, muscle fatigue, asplenia, miosis, migraine, dyslexia and ichthyosis.

A new multifacetted syndrome inherited as an autosomal, dominant trait is described encompassing not only two hitherto undescribed hereditary defects--thrombocytopathia and asplenia--but also muscle contractile defect, migraine-like headache, miosis, dyslexia and ichthyosis. None of these defects has so far been assigned to a specific chromosome or linkage group. Further studies on the various aspects of the syndrome are in progress.

The Experiences of Compassion Fatigue in Oncology and Palliative Care Nursing: A Scoping Review.

PURPOSE: Oncology and palliative care nursing involves prolonged exposure to suffering, death, and emotionally demanding care, placing nurses at heightened risk of compassion fatigue. Although previous research has identified associated risk and protective factors, less attention has been given to understanding how compassion fatigue develops and is sustained within clinical practice. This scoping review aimed to examine the emotional, relational, individual, and organizational processes shaping compassion fatigue among nurses working in oncology and palliative care settings. METHODS: A scopi…

Fatigue in Dental Ceramics: A Call for Standardized Testing and Emerging Manufacturing Technologies.

In recent decades, dental ceramics have undergone substantial technological and scientific advancement, consolidating their role as key materials for esthetic and functional oral rehabilitation [...].

Fatigue in Parkinson's Disease: A Cross-Sectional Study of Prevalence and Clinical Correlates.

BACKGROUND AND OBJECTIVES: Fatigue is a non-motor symptoms (NMS) of Parkinson's disease (PD). The study aimed to determine the frequency and severity of fatigue, its predictors, and its impact on quality of life. METHODS: We included 150 patients with PD. The Fatigue Severity Scale (FSS) and the Parkinson Fatigue Scale-16 (PFS-16) were used to assess the presence and severity of fatigue. RESULTS: The frequency of fatigue was 46%, predominantly of mild severity. The mean FSS score was 33.3 ± 10.3. Patients with fatigue were older, had a longer disease duration, received higher levodopa doses,…