Результаты поиска

Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review.

INTRODUCTION: Stiff-person syndrome (SPS) is a rare neurological disorder that causes progressive muscle rigidity, gait disturbances, and functional impairment; type 1 is autoimmune, with positive anti-GAD antibodies (Ab), while type 2 is paraneoplastic and associated with antiamphiphysin Ab. CASE PRESENTATION: A 41-year-old man with a silent medical history presented with stiffness and functional impairment; after numerous rheumatological and neurological investigations, he was diagnosed with SPS, with evidence of high titer anti-GAD Ab. After treatment with benzodiazepines was started, the

Anti-fracture Efficacy of Monthly Risedronate Compared with That of Weekly Risedronate in Postmenopausal Korean Women with Osteoporosis: A Nationwide Cohort Study.

BackgroundIntermittent dosing regimens for oral risedronate (once-monthly and once-weekly) were developed for patient convenience. While several studies have reported the anti-fracture efficacy of weekly dosing, few have assessed monthly dosing. The lower efficacy of monthly dosing has been previously suggested. The aim of this study was to compare the anti-fracture efficacy of monthly and weekly dosing.MethodsWe obtained information from the Korea National Health Insurance Service database from 2012 to 2017 of Korean women of ≥50 years of age who used weekly or monthly risedronate. We compare

Совпадение в полном тексте источника
… American Association of Clinical Endocrinologists and American College of Endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis: 2016. Endocr Pract. 2016;22(Suppl 4):1–42. doi: 10.4158/EP161435.GL. 19. …

Clinical significance of Ki-67 in patients with lung adenocarcinoma in situ complicated by type 2 diabetes.

BackgroundThe increasing number of type 2 diabetes mellitus (T2DM) patients leads to higher rates of morbidity and mortality related to lung cancer.AimTo investigate the utility of the proliferating cell nuclear antigen Ki-67 in patients with lung adenocarcinoma in situ (AIS) complicated by T2DM.MethodsOne hundred patients with AIS and T2DM (group A), 100 patients with AIS alone (group B), and 60 patients with benign lung lesions (group C) admitted to the Department of Thoracic Surgery and Endocrinology of the First Affiliated Hospital of Soochow University from November 2021 to December 2022

Совпадение в полном тексте источника
… Therefore, thoracic surgeons and endocrinologists should pay special attention to the postoperative results of these patients and emphasize the necessity of regular follow-up. …

Do Legal Issues Deserve Space in Specialty Medical Journals ?

Physicians and Internists in India have tended to brush under the carpet legal issues affecting their profession. Of concern to all Physicians is the judgment in a recent case where the NCDRC has stated that if MD Medicine Physicians write Physician & Cardiologist on their letterhead it is Quackery. What is MD Medicine degree holder in India qualified and trained to treat ? These are issues which need debate and that can only be initiated once we recognize that there is a problem. Either an MD Medicine is a cardiologist or he is not. If he is then it is the bounded duty of the Association of P

Indications for Sleeve Gastrectomy-Is It Worth Waiting for Comorbidities to Develop?

(1) Background and Objectives: Morbid obesity significantly increases the prevalence of comorbidities, such as heart disease, restrictive lung disease, stroke, diabetes mellitus and more. (2) Methods: Patients undergoing gastric sleeve surgery were divided into three groups with BMI between 30-34.9 kg/m2 (Group I), 35-39.9 kg/m2 (Group II), and over 40 kg/m2 (Group III). Preoperative examinations included cardiac ultrasound, respiratory function and laboratory tests, and preoperative comorbidities were also recorded. Following a one-year follow-up, we compared the rate of weight loss in the th

Совпадение в полном тексте источника
… Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient—2013 update: Cosponsored by American association of clinical endocrinologists, The obesity society, and American society for metabolic & bariatric surgery Surg. Obes. …

Association between Hyperglycemia and Medication-Related Osteonecrosis of the Jaw (MRONJ).

BACKGROUND: Medication-related osteonecrosis of the jaw (MRONJ) is a type of jawbone necrosis caused by the use of drugs for some types of cancer and osteoporosis. The current study aimed to evaluate the associations between hyperglycemia and the development of medication-related osteonecrosis of the jaw. METHODS: Our research group investigated data collected between 1 January 2019 and 31 December 2020. A total of 260 patients were selected from the Inpatient Care Unit, Department of Oromaxillofacial Surgery and Stomatology, Semmelweis University. Fasting glucose data were used and included

Совпадение в полном тексте источника
… In conclusion, the clinical therapy of MRONJ can be challenging, and a multidisciplinary approach involving dentists, oral surgeons, and endocrinologists may be necessary. The choice of therapy depends on the severity of the condition and the individual patient’s response to treatment. …

Skeletal consequences of heart failure.

Heart failure (HF) is a prevalent clinical syndrome that causes significant physical limitations. Osteoporosis is also an important cause of loss of functionality, and it mainly affects women. There are several reports linking HF and osteoporosis, and both share risk factors. Most of the data available so far point to bone fragility as a consequence of HF, and several mechanisms have been identified to explain this relationship. Among the proposed pathophysiological mechanisms are the hyperactivation of the renin-angiotensin-aldosterone system and the increase in parathyroid hormone, functiona

Совпадение в полном тексте источника
… Eur J Heart Fail 2020 ; 22 ( 8 ): 1342 – 1356 . 32483830 10.1002/ejhf.1858 PMC7540043 6 Camacho PM Petak SM Binkley N , et al American Association of Clinical Endocrinologists/American College of Endocrinology Clinical Practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis …

2022 American Society of Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) Indications for Metabolic and Bariatric Surgery.

MAJOR UPDATES TO 1991 NATIONAL INSTITUTES OF HEALTH GUIDELINES FOR BARIATRIC SURGERY: Metabolic and bariatric surgery (MBS) is recommended for individuals with a body mass index (BMI) >35 kg/m2, regardless of presence, absence, or severity of co-morbidities.MBS should be considered for individuals with metabolic disease and BMI of 30-34.9 kg/m2.BMI thresholds should be adjusted in the Asian population such that a BMI >25 kg/m2 suggests clinical obesity, and individuals with BMI >27.5 kg/m2 should be offered MBS.Long-term results of MBS consistently demonstrate safety and efficacy.Appropriately

Совпадение в полном тексте источника
… Mechanick JL Apovian C Brethauer S Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric surgery-2019 update: co-sponsored by the American Association of Clinical Endocrinologists/American College of Endocrinology, The Obesity … Mechanick JL Kushner RF Sugerman HJ American Association of Clinical Endocrinologists, The Obesity Society, and the American Society for Metabolic and Bariatric Surgery medical guidelines for clinical practice for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery …

Analysis of Preventive Effect of Bisphosphonate for Osteoporotic Fracture in Patients with Alzheimer's Disease and Patient Mortality.

Background: Alzheimer's disease (AD) is the most common neurodegenerative disease in the older adult population and is often associated with reduced physical activity. Reduced activity and mechanical loading subsequently reduce bone mineral density and increase risk of osteoporosis. Bisphosphonates (BPs) offer preventative effects on osteoporotic fractures in the general population, but their effects on patients with AD are less known. This study aimed to assess the impact of BPs on osteoporotic fractures and survival in patients with AD. Methods: In this nationwide retrospective cohort study,

Совпадение в полном тексте источника
… American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Postmenopausal Osteoporosis: Executive Summary of Recommendations. Endocr. Pract. Off. J. Am. Coll. Endocrinol. Am. Assoc. Clin. …

Effect of Baduanjin exercise on primary osteoporosis: study protocol for randomized controlled trial.

BackgroundLack of exercise is often a major cause of chronic disease. Osteoporosis (OP) is a chronic disease with multifactorial co-morbidity. Baduanjin (BDJ) exercise may be a powerful tool for modifying risk factors. The aim is to provide more evidence about the effectiveness of BDJ exercise in improving pain and balance ability in patients with OP.MethodsIn the prospective randomized controlled trial, 160 participants will be recruited and randomized to the treatment group (BDJ exercise combined with Calcium carbonate and D3) or the control group (Calcium carbonate and D3) at 1:1 ratio. Par

Совпадение в полном тексте источника
… American Association of Clinical Endocrinologists and American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis - 2016--Executive Summary. Endocr Pract. 2016;22(9):1111–8. 10.4158/EP161435.ESGL. 12. …

Idiopathic osteoporosis, Ehlers-Danlos syndrome, postural orthostatic tachycardia syndrome, and mast cell activation disorder in a 27-year-old male patient: A unique case presentation.

A young male patient presents with widespread pain and varying chronic inflammatory symptoms for three years and idiopathic low bone density for more than ten years. Based on the patient's clinical history, the patient has been diagnosed with an hypermobile Ehlers-Danlos syndrome, postural orthostatic tachycardia syndrome, and mast cell activation disorder trifecta with affiliated inflammation-induced osteoporosis.

A Multicenter Analysis of Clinical Features and Long-Term Outcomes of POEMS Syndrome in Korea.

BackgroundPOEMS syndrome is a rare form of plasma cell dyscrasia characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal proteins, and skin changes. Owing to its low incidence, there are few reports regarding this syndrome. This multicenter study included 84 patients diagnosed with POEMS syndrome in South Korea.MethodsWe retrospectively evaluated 84 patients diagnosed with POEMS syndrome at 8 hospitals in South Korea between January 2000 and October 2022. The clinical characteristics and treatment outcomes were analyzed.ResultsThe median patient age was 53 years (range, 26-77

Совпадение в полном тексте источника
… Therefore, a multidisciplinary approach by hematologists, neurologists, and endocrinologists is essential for accurate and early diagnosis of POEMS syndrome. There is no consensus regarding the treatment of this syndrome. …

Hematologic malignancies magnify the effect of body mass index on insulin resistance in cancer survivors.

Cancer survivors are at increased risk of type 2 diabetes, which usually develops from obesity and insulin resistance. Whether diabetes susceptibility is due to shared risk factors for cancer and insulin resistance or directly related to cancer and its treatment is unknown. We investigated effect modification between malignancy and body mass index (BMI) as determinants of insulin sensitivity in patients with hematologic malignancies and controls without cancer. In a cross-sectional study of 43 individuals without diabetes (20 patients with treated hematologic malignancies; 23 controls without

Совпадение в полном тексте источника
… intervention and education, (2) research to address whether cancer survivors require more aggressive screening or treatment schedules for hypertension, dyslipidemia, obesity, or impaired glucose tolerance than those recommended by standard guidelines, and (3) earlier referrals to specialists, including endocrinologists …

Cost-effectiveness of preventative therapies for postmenopausal women with osteopenia.

BackgroundLimited data are available regarding the cost-effectiveness of preventative therapies for postmenopausal women with osteopenia. The objective of the present study was to evaluate the cost-effectiveness of raloxifene, alendronate and conservative care in this population.MethodsWe developed a microsimulation model to assess the incremental cost and effectiveness of raloxifene and alendronate relative to conservative care. We assumed a societal perspective and a lifetime time horizon. We examined clinical scenarios involving postmenopausal women from 55 to 75 years of age with bone mine

Совпадение в полном тексте источника
… Clarke BL, Gray TK, Harris DW, Johnston CC, Jr, Kleerekoper M, Lindsay R, Luckey MM, McClung MR, Nankin HR, Petak SM, Recker RR, Anderson RJ, Bergman DA, Bloomgarden ZT, Dickey RA, Palumbo PJ, Peters AL, Rettinger HI, Rodbard HW, Rubenstein HA, AACE Osteoporosis TF American Association of Clinical Endocrinologists …

Secondary fracture prevention in primary care: a narrative review.

The global burden of osteoporosis continues to rise with an ageing population. Untreated osteoporotic fractures not only heighten the risk of subsequent fractures but are associated with excess mortality. Although primary care guidelines consistently stress the importance of secondary fracture prevention, fewer than 20% of patients are appropriately treated for osteoporosis following an initial osteoporotic fracture. This worldwide phenomenon is known as the osteoporosis care gap. This literature review examines the barriers to secondary fracture prevention in primary care and evaluates the ef

Синдром Сусака: история инвалидности из-за позднего признания.

Синдром Сусака является редкой провокационной микроангиопатией, характеризующейся триадой ретинопатии, энцефалопатии и потери слуха. Синдром вызывает повторяющиеся микроинфаркты в этих органах, которые, в свою очередь, проявляются в неоднократных атаках, связанных с потерей визуального поля, потерей слуха и слуха, а также различными синдромами мозга. Это часто приводит к значительному накоплению инвалидности с течением времени, особенно в случае задержек или неудач в диагностике. Повреждения мозга, связанные с этим заболеванием, могут быть похожи на повреждения, вызванные множественным склероз

The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of erectile dysfunction.

PURPOSE: Erectile dysfunction (ED) is one of the most prevalent male sexual dysfunctions. ED has been in the past mistakenly considered a purely psycho-sexological symptom by patients and doctors. However, an ever-growing body of evidence supporting the role of several organic factors in the pathophysiological mechanisms underlying ED has been recognized. METHODS: The Italian Society of Andrology and Sexual Medicine (SIAMS) commissioned an expert task force involving several other National Societies to provide an updated guideline on the diagnosis and management of ED. Derived recommendations

Совпадение в полном тексте источника
… The project was actively supported by several other National Societies including the Italian Society of Endocrinology (Società Italiana di Endocrinologia, SIE), the Association of Clinical Endocrinologists (Associazione Medici Endocrinologi, AME), the Italian Society of Diabetology (Società Italiana …

Новое развитие аутоиммунного расстройства после лечения иммунной реконституции при множественном склерозе.

Иммунная реконституционная терапия (IRT) является относительно новым и высокоэффективным средством лечения множественного склероза (MS). Неопределенность в отношении развития аутоиммунных расстройств (АД) после сохранения некоторых методов лечения. Цель этого исследования состояла в том, чтобы провести оценку новых разработок в области АД после IRT у пациентов с РС и описать характер этих АД и время их начала. В исследование было включено в общей сложности 179 пациентов с множественным склерозом (37 после аналоговой трансплантации гематопоэтических стволовых клеток (АХСТ), 19 пациентов после а

Building a comprehensive cancer survivorship program.

There is a significant increase in the number of people surviving cancer as a result of improved detection and better treatments. In the United States (US) alone, these numbers are estimated to reach 20 million by 2026 [Miller et al (2016) CA Cancer J Clin 66(4) 271-289)]; [Bluethmann et al (2016) Cancer Epidemiol Biomarkers Prev 25(7) 1029-1036]. Living through cancer treatment represents a life-changing event, often including residual and long-term emotional, physical, psychological and spiritual sequelae. Survivorship programming must encompass the clinical management of medical issues, loc

Совпадение в полном тексте источника
… Oncocardiologists, endocrinologists, dentists and fertility specialists are examples of the more common specialists who can contribute to providing coordinated survivorship care. These providers can work hand-in-hand with the survivorship team and PCPs to provide comprehensive care. …

Multiple Myeloma: Risk Stratification and Toxicity Management

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.