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Predicting incontinence and erectile function after prostate cancer surgery: International validation of models.

BACKGROUND: Our objective is to externally validate the most accurate, published tools predicting urinary incontinence and erectile dysfunction following prostatectomy. Several models have been developed to predict the risks of adverse events, though most have not been externally validated. METHODS: Data were obtained from the Prostate Cancer Outcomes Registry of Australia and New Zealand (PCOR-ANZ). Self-reported urinary incontinence and erectile dysfunction were measured using EPIC-26 at 12 months after radical prostatectomy. Four predictive models were selected for external validation, bei…

Gonadal dysfunction in male patients with Budd Chiari syndrome and its reversibility with treatment.

BACKGROUND AND AIMS: Budd Chiari syndrome (BCS) commonly affects adolescents and adults. With improved survival, important quality-of-life p … TS: Sixteen (53.3%) out of 30 patients were sexually active at the time of study and 5/16 (31%) had erectile dysfunction. Hypogonadotropic hypogonadism (HH) was the most common pattern seen in 50% cases followed by hypergonadotropic hypogonadism (HyH) in 23% cases. 27% patients had eugonadism. At 6 months of treatment, 60% of patients in HH group became eugonadal as c …

Does the positive intracavernous papaverine test always indicate a normal penile vascular system?

OBJECTIVE: A positive intracavernous papaverine test has been presumed to determine normal erectile hemodynamics. Recently, positive erectile responses to intracorporeal injection tests were reported in patients with penile arterial insufficiency. METHODS: This hypothesis was assessed by obtaining hemodynamic data using color Doppler ultrasonography in 417 patients with erectile dysfunction aged between 20 and 73 years (mean 43.06 +/- 13.66). A normal penile vascular system was found in 95 patients (22.79%), veno-occlusive dysfunction in 76 (18.22%), arteriogenic erectile dysfunction (ED) in …

The erectile and ejaculatory implications of the surgical management of rectal cancer.

Colorectal cancer is a significant cause of cancer-related deaths worldwide. Although advances in surgical technology and technique have decreased mortality rates, surviving patients often experience sexual dysfunction as a common complication. The development of the lower anterior resection has greatly decreased the use of the radical abdominoperineal resection surgery, but even the less radical surgery can result in sexual dysfunction, including erectile and ejaculatory dysfunction. Improving the knowledge of the underlying causes of sexual dysfunction in this context and developing effectiv

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… dysfunction. … Erectile dysfunction. Am Fam Physician. 2016;94(10):820–7. 70. McMahon CG. Current diagnosis and management of erectile dysfunction. Med J Aust. 2019;210(10):469–76. 71. Dhaliwal A, Gupta M. PDE5 inhibitors. StatPearls Publishing LLC: Treasure Island (FL); 2022. 72. …

[Investigation and analysis of chronic prostatitis and sexual dysfunction].

OBJECTIVE: To investigate the prevalence of sexual dysfunction in chronic prostatitis patients and its relation with patients' age and the c … s with chronic prostatitis was 49.0% : 26.2% of the subjects with premature ejaculation, 15.0% with erectile dysfunction and 7.7% with both premature ejaculation and erectile dysfunction. CONCLUSION: The prevalence of sexual dysfunction in patients with chronic prostatitis is high, which is negatively correlated with both the age of the patients (P < 0.001) and the c …

[Cavernosography using digital luminescence radiography (DLR) in the diagnosis of venous induced erectile function and of diseases of the corpus cavernosum].

Dynamic cavernosography is the most important technique for identifying and localizing venous leakage in erectile dysfunction. The use of digital radiography with a greater degree of tolerance in the exposure, a more dynamic signal, and a shorter exposure time can enhance the diagnostic value of conventional cavernosography. A further advantage of the method is the lower dosage required, which means that the gonads are exposed to less radiation. For 30 patients with erectile dysfunction and 7 other cases, conventional cavernosography images were compared with those obtained by this new method.…

Functional crackers from tiger nut, unripe plantain, and sorghum flours improve vascular and sexual health in hypertensive rats.

BackgroundHypertension, erectile dysfunction, and dyslipidemia are interrelated conditions strongly driven by poor dietary habits dominated by refined carbohydrate snacks and high-fat fast foods.AimThis study investigated the potential of functional crackers formulated from tiger nut, unripe plantain, and sorghum flours to ameliorate N-nitro-l-arginine methyl ester and high-fat diet-induced hypertension and erectile dysfunction in Wistar rats.MethodsComposite crackers were prepared in different proportions and evaluated for effects on blood pressure, sexual behavior, lipid profile, nitric oxid…

Role of hydrogen sulfide in the male reproductive system.

As an important gas signaling molecule, hydrogen sulfide (H2S) affects multiple organ systems, including the nervous, cardiovascular, digestive, and genitourinary, reproductive systems. In particular, H2S not only regulates female reproductive function but also holds great promise in the treatment of male reproductive diseases and disorders, such as erectile dysfunction, prostate cancer, varicocele, and infertility. In this review, we summarize the relationship between H2S and male reproductive organs, including the penis, testis, prostate, vas deferens, and epididymis. As lower urinary tract …

How, why and when should urologists evaluate male sexual function?

Male sexual dysfunction-a term that is commonly used to refer to erectile dysfunction, premature ejaculation, decreased libido and impaired orgasm-is the primary complaint encountered by many urologists. Despite the high prevalence and bothersome nature of these complaints, they are frequently neglected in clinical practice. This paper highlights clinical situations in which urologists should systematically evaluate male sexual functioning. These include men who present with several common urologic disorders, such as pelvic trauma, malignancies, and lower urinary tract symptoms associated with…

The use of vibrotactile stimulation for determining sexual potency in the laboratory in men with erectile problems: methodological considerations.

Vibrotactile stimulation, when used in combination with visual sexual stimulation, has been shown to enhance erectile response in sexually functional men. The present study attempted to describe a diagnostic methodology, including the development and application of a new mini-vibrator, that might enhance penile response in men with erection problems. Tests on 78 men with either erectile dysfunction (ED), or a combination of erectile dysfunction and premature ejaculation (ED+PE), showed that vibratory stimulation together with an erotic video (EV+VT), produced greater penile response than the e…

[The role of tadalafil in the management of sexual dysfunctions].

Erectile dysfunction (ED) has a significant negative impact on the quality of life of the patients and their partners. The sequence and regimens of ED therapy have become quite evident since the advent of phosphodiesterase type 5 inhibitors (PDE-5). However, there have been continued basic research of the efficacy and safety of these agents and studies aimed at new therapeutic goals. In recent years, the attention of researchers has shifted into a wider range of issues related to the personalized PDE-5 therapy, including sexual satisfaction, psychosocial variables (e.g., confidence, self-estee…

Specific aspects of erectile function in urology/andrology.

The urologist/andrologist is the specialist responsible for diagnosis and treatment of health problems related to the genitourinary tract, and his or her participation in comprehensive care for a patient with erectile dysfunction (ED) is fundamental and often indispensable. The urologists/andrologists should characterize the origin of ED because of their knowledge and familiarity of all diagnostic tests and second- and third-line therapy. The origin of ED is important to determine for various reasons, such as young people suitable for etiologic treatment, medicolegal reasons, or patients' wish…

[Current status of the study of genital sympathetic evoked potentials in the assessment of impotence].

OBJECTIVE: To determine the usefulness of penile sympathetic skin response (PSSR) in the study of impotence. METHODS: The PSSR, hand sympathetic skin response (HSSR), filling videocystography and SPACE (single potential analysis cavernous electromyography) were performed in 39 patients referred for study of impotence. RESULTS: A relationship between not obtaining PSSR and an open bladder neck (60%) in the videocystography at filling, and between a closed bladder neck and obtained PSSR (81%) was demonstrated. The percentage of normal hand sympathetic potentials was similar for patients with o

Assessment and treatment of impotence.

Impotence is a common problem. History is primarily relied on to diagnose psychogenic impotence. Sex therapy is an effective treatment. Antihypertensive and psychiatric medicines often cause impotence, but most medicines should be considered a cause if this is supported by the history. Hormonal causes should be suspected in a patient with decreased libido or decreased testicular size, and testosterone should be measured in these cases. Hormone replacement may restore sexual function in hypogonadal men. Doppler sonogram or arteriography should be used to diagnose vascular impotence for men who

[Impotence].

"Impotence" is a vague term for a variety of sexual dysfunctions in the male, such as libido disturbance, erectile impotence, dyspareunia and a number of ejaculatory problems. They are very rarely caused and maintained by any single factor. Usually a combination of organic and psychic factors is involved; the symptoms may give some indication as to what factors are dominant. Organic and surgical treatment should be considered cautiously and should have a clear indication. Frequent psychic causes are partnership or personality problems and the so-called vicious circle of performance anxiety. Se

Male sexual dysfunction.

Impotence and premature ejaculation are common male sexual dysfunctions that are present in most adult primary care populations. New information about the vascular and neurophysiologic mechanisms of impotence have been joined by new technology to advance the medical practices in the diagnosing and treating of the impotent male. While similar advances have not occurred in the understanding of premature ejaculation, behavior therapy techniques are extremely effective with motivated couples. Primary care physicians can aid male patients with sexual dysfunction by attempting to identify them, init