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Inflammation markers in cutaneous melanoma - edgy biomarkers for prognosis.

BACKGROUND: Parasitic infections of the gastrointestinal tract is one of the highest causes of morbidity and mortality among HIV infected individuals. This is due to the colonization of the intestinal tract by parasites influenced by induced enteropathy caused by HIV infection. CD+4 t-lymphocytes count is a marker of the immune status of HIV infected individuals. OBJECTIVE: This study investigated the prevalence of gastrointestinal parasitic infections among HIV coinfected individuals in relation to their immunological status. METHODS: CD+4 t-lymphocytes count was determined using fluorescen

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… The European countries we are using in our analysis are the following: Austria, Belgium, Bulgaria, Croatia, Cyprus, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Romania, Slovakia …

Фрейлти и ее связь с психическим здоровьем и качеством жизни в множестве склерозов: перекрестное исследование.

С увеличением среднего возраста людей с множественным склерозом (MS) возникают такие возрастные синдромы, как слабость, в качестве новых вызовов для здоровья пациентов. Предварительные исследования по вопросу о слабости в РС были сосредоточены главным образом на физических аспектах, в результате чего связь между слабостью и психическим здоровьем не была изучена. ЦЕЛЬ: изучение связей между слабостью, психическим здоровьем и качеством жизни (QoL) у людей, имеющих MS. DESIGN: Исследование на основе перекрестных вопросников, проведенное в Центре по оказанию медицинской помощи инвалидам при Медици

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… Psychometric properties of the HADS measure of anxiety and depression among multiple sclerosis patients in Croatia. Front Psychol 2021; 12: 794353. 17. Vickrey BG, Hays RD, Harooni R, et al. A health-related quality of life measure for multiple sclerosis. Qual Life Res 1995; 4(3): 187–206. 18. …

Ассоциация < < Средиземное питание > > и < < Развитие множественного склероза: систематический обзор и мета-анализ > > .

Множественный склероз (MS) является хроническим воспалительным заболеванием центральной нервной системы. С учетом противоречивых данных о влиянии соблюдения средиземноморской диеты (MedDiet) на развитие НР и отсутствия систематического обзора по этой теме цель настоящего исследования состояла в изучении этой ассоциации. МЕТОДЫ: В соответствии с методами PrISMA и JBI до марта был проведен поиск электронных баз данных через PubMed, Embase, Web of Science и Scopus 2024. В него были включены первоначальные клинические исследования по оценке связи между присоединением к MedDiet и разработкой MS. Ри

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… Sepcic . 2009 . “ Multiple Sclerosis and Cancers in Croatia—A Possible Protective Role of the “Mediterranean Diet” .” Collegium Antropologicum 33 , no. 2 : 539 – 545 . 19662776 Cavalla , P. , and M. Vercellino . 2023 . “ May Mediterranean Diet Contribute to Reduce Risk of Multiple Sclerosis? …

Risk Factors of Infection in Relapsed/Refractory Multiple Myeloma Patients Treated with Lenalidomide and Dexamethasone (Rd) Regimen: Real-Life Results of a Large Single-Center Study.

Lenalidomide-based regimens are effective treatment options for patients with relapsed/refractory multiple myeloma (RRMM). However, they are associated with an increased risk of infectious complications. This study examines the clinical factors influencing the occurrence of infection in MM patients treated with lenalidomide and dexamethasone (Rd). A retrospective analysis of all patients who received the Rd regimen between 2017 and 2021 at our institution was performed. The study group consisted of 174 patients and the median age was 65 years. Most patients (n = 110, 63.2%) received the Rd tre

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… IntechOpen Rijeka, Croatia 2018 Ch.8 10.5772/intechopen.81683 15. Teh B.W. Harrison S.J. Worth L.J. Thursky K.A. Slavin M.A. Infection risk with immunomodulatory and proteasome inhibitor–based therapies across treatment phases for multiple myeloma: A systematic review and meta-analysis Eur. J. …

Association of Wnt Inhibitors, Bone Mineral Density and Lifestyle Parameters in Women with Breast Cancer Treated with Anastrozole Therapy.

AimTo determine the levels of Wnt inhibitors in patients treated with aromatase inhibitors (AIs) prior to therapy and to investigate their association with bone mineral density (BMD) and lifestyle parameters.Methods137 breast cancer patients were divided into a group treated with 1 mg of anastrozole and a group w/o anastrozole therapy. Serum concentrations of sclerostin and dickkopf1 (DKK1) were measured by ELISA. BMD was measured by dual-energy X-ray absorptiometry (DXA). Lifestyle factors were investigated by a self-reported questionnaire.ResultsSclerostin was significantly higher in the AI-

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… Strossmayer University of Osijek, Osijek, Croatia—grant’s numbers: VIF-2017-MEFOS-5 (to M.S.) and VIF-2017-MEFOS-2 (to A.V.). Conflicts of Interest The authors declare no conflict of interest. References 1. Dowsett M. Cuzick J. Ingle J. Coates A. Forbes J. Bliss J. Buyse M. Baum M. Buzdar A. …

The 48th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians - Oral Sessions (O009-O155).

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… Department D’Hematologie, Nantes, France, 20 S.S.C.V.D Trapianto di Cellule Staminali, A.O.U Citta della Salute e della Scienza di Torino, Torino, Italy, 21 Hospital Reina Sofia, Córdoba Hospital, Cordoba, Spain, 22 University Hospital Center Zagreb, School of Medicine, University of Zagreb, Zagreb, Croatia … Hematologie, Nantes, France, 12 CHU Lapeyronie, Département d`Hématologie Clinique, Montpellier, France, 13 University Hospital Muenster, Muenster, Germany, 14 BMT Unit and CBMDP Donor Center, University of Patras, Patras, Greece, 15 University Hospital Centre Zagreb, Zagreb School of Medicine, Zagreb, Croatia …

Abstracts of the 12th European Cytogenomics Conference 2019 : Salzburg, Austria. 6-9 July 2019

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:: 8th Европейский конгресс фармацевтики: выдержки из выступлений

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… Harmonized educational tools for valproate-containing medicines have been successfully implemented in Croatia, aiming to both patients and healthcare professionals. References 1. Meador K, Reynolds MW, Crean S, et al. … Barbara Kovačić Bytyqi Agency for Medicinal Products and Medical Devices of Croatia (HALMED) Medicines ought to have favourable benefit-risk profile for the treatment of patients in their authorised indication(s) in order to remain on the market. …

Relative Risk of Death in Bulgarian Cancer Patients during the Initial Waves of the COVID-19 Pandemic.

BackgroundThe COVID-19 pandemic has led to millions of documented deaths worldwide, with diverse distribution among countries. Surprisingly, Bulgaria, a middle-income European Union member state, ranked highest in COVID-19 mortality. This study aims to assess whether Bulgarian cancer patients experienced a higher relative risk (RR) of death compared to the general Bulgarian population during the pandemic.Materials and methodsData from the Bulgarian National Statistical Institute and the Bulgarian National Cancer Registry were analyzed to estimate monthly RR of death in cancer patients compared

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… A comparison of health system responses to COVID-19 in Bulgaria, Croatia and Romania in 2020 Health Policy 2022 126 456 464 10.1016/j.healthpol.2022.02.003 35221121 PMC8851743 24. Steinert J.I. Sternberg H. Prince H. Fasolo B. Galizzi M.M. Büthe T. Veltri G.A. …

Коэффициент сокращения моноклонального белка в качестве полезного прогнозного фактора в стандартной группе риска, недавно диагностированной множественной миеломы.

Множественная миелома (ММ) — обычная гематологическая гелингология, которая исходит из злокачественного клона плазменных клеток. Однолитровая плазмоцитома, история диабета и количество тромбоцитов считаются прогнозными факторами для MM. Но некоторые пациенты все еще связаны с гораздо худшими результатами без каких-либо предсказателей. Цель этого исследования заключалась в том, чтобы проследить темпы сокращения моноклонального белка (М протеина) после первого и четвертого циклов химиотерапии, который считается новым прогнозным фактором для беспрогрессивного выживания (ПФС) в группе стандартного

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… in press: August 1, 2023 Specialty type: Medicine, research and experimental Country/Territory of origin: China Peer-review report’s scientific quality classification Grade A (Excellent): 0 Grade B (Very good): 0 Grade C (Good): C Grade D (Fair): 0 Grade E (Poor): 0 P-Reviewer: Roganovic J, Croatia …

Demographic shift disproportionately increases cancer burden in an aging nation: current and expected incidence and mortality in Hungary up to 2030.

BACKGROUND: Population aging is a common demographic pattern in developed countries, and aging increases the risk of cancer. The disproportionately high cancer burden, as a consequence, is especially pronounced in Central and Eastern European countries, including Hungary. METHODS: We summarized current and projected future cancer incidences and mortalities utilizing data from the last two decades. Predictions are based on cancer incidence and mortality collected between 1996 and 2015 in Hungary. In addition to the crude rates, data were age standardized to the European standard population (ES

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… Among 40 European countries, the incidence of lung and bronchus cancer (LC), colon and rectum cancer (CRC), and oral cavity-pharynx cancers is highest in Hungary among both males and females. 1 , 3 Neighboring countries, such as the Czech Republic, Slovenia, Slovakia, Croatia, and Serbia, experience …

Распространение остеопороза в хронических заболеваниях: зонтичный обзор 283 наблюдения, полученные в ходе 13 систематического обзора.

ВВЕДЕНИЕ: Остеопороз - это болезнь, характеризующаяся снижением плотности минералов кости и ухудшением микроархитектуры кости, что повышает риск разрушения. В контексте различных хронических патологий это состояние может привести к еще более высокому уровню заболеваемости, смертности и бремени здравоохранения. ЦЕЛЬ: Обобщать и сопоставлять имеющиеся данные, полученные в ходе систематических обзоров распространения остеопороза среди различных хронических заболеваний. МЕТОДОЛОГИЯ: В соответствии с руководящими принципами ПРИСМА был проведен зонтичный обзор с уделением особого внимания систематич

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… United States Adult patients with cystic fibrosis, mean age 28.2 years (18.5–32) years Systematic review and meta-analysis Cystic Fibrosis Diagnosis based on clinical and genetic criteria Bone densitometry (DXA), T-score <= -2.5 Ramírez (2017) 5 905 Spain, France, Netherlands, Germany, Morocco, Turkey, Croatia …

Effectiveness of Convalescent Plasma Therapy in COVID-19 Patients with Hematological Malignancies: A Systematic Review.

Background: Immunocompromised patients, including those with hematological malignancies, are at a high risk of developing severe coronavirus disease 2019 (COVID-19) complications. Currently, there is a limited number of systematic reviews into the efficacy of convalescent plasma therapy (CPT) use in the treatment of COVID-19 patients with hematological malignancies. Therefore, the aim of this review was to systematically appraise the current evidence for the clinical benefits of this therapy in COVID-19 patients with hematological malignancies. Methods: A comprehensive search was conducted up

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… States | Hematologic cancer | Retrospective cohort study | 143/823 | 65 years | NA | Luetkens et al. [ 16 ] | 2020 | United States | MM | Case report | 1/0 | 72 years | F | 3 ASCT Moore et al. [ 17 ] | 2020 | United States | NHL | Case report | 1/0 | 63 years | F | Malsy et al. [ 18 ] | 2020 | Germany Croatia …

Management of bone health in patients with cancer: a survey of specialist nurses.

BackgroundPatients with cancer can experience bone metastases and/or cancer treatment-induced bone loss (CTIBL), and the resulting bone complications place burdens on patients and healthcare provision. Management of bone complications is becoming increasingly important as cancer survival rates improve. Advances in specialist oncology nursing practice benefit patients through better management of their bone health, which may improve quality of life and survival.MethodsAn anonymised online quantitative survey asked specialist oncology nurses about factors affecting their provision of support in

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… Table 1 Demographics, specialties and roles of survey participants DXA , dual energy X-ray absorptiometry Austria ( n = 1), Azerbaijan ( n = 1), Croatia ( n = 1), Cyprus ( n = 1), Denmark ( n = 1), France ( n = 1), Greece ( n = 2), Italy ( n = 1), Malta ( n = 2), Netherlands ( n = 10), Portugal ( n = …

Резюме: 31 Европейский конгресс патологии.

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… Hospital, Zagreb, Croatia, 4 University of Zagreb, School of Medicine, Croatia, 5 Institute of Pathology, School of Medicine, University of Zagreb, Croatia, 6 Department of Paediatrics, Children's Hospital Zagreb, Croatia, 7 Polyclinic Dr. … Vlasic, Split, Croatia, 8 Department of Nephrology and Dialysis, Dubrava University Hospital, Zagreb, Croatia Background & Objectives: Alport spectrum disorders are genetically heterogenic disorders caused by COL4A3, COL4A4 or COL4A5 mutations. …

Global trends in CAR-T cell therapy for multiple myeloma: A bibliometric analysis, 2013-2025.

CAR-T cell therapy has dramatically changed the treatment paradigm for relapsed/refractory multiple myeloma (R/R MM). Nevertheless, there is a notable paucity of comprehensive bibliometric analyses within this specialized domain. On January 26, 2026, publications on CAR-T cell therapy for MM (2013-2025) were retrieved from the Web of Science Core Collection using: TS = (CAR-T OR "chimeric antigen receptor T*" OR "chimeric antigen receptor modified T" OR "chimeric antigen receptor engineered T" OR "chimeric antigen receptor transduced T" OR "chimeric antigen receptor redirected T") AND TS = ("m

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… Notably, Russia (centrality = 0.78), Saudi Arabia (centrality = 0.66), and Croatia (centrality = 0.45) exhibit high intermediary centrality, suggesting that these countries play a crucial role as bridges within the international collaboration network. …

Global Burden of Rare Cancers: Insights from GLOBOCAN 2022 Estimates.

Background: Rare cancers, defined as those with an incidence rate of fewer than 6 cases per 100,000 individuals, contribute to a substantial portion of the global cancer burden. Despite their impact, they receive less attention than more common malignancies, leading to challenges in early detection, treatment strategies, and research funding. This study aims to assess the global incidence and mortality patterns of rare cancers in 2022 to better understand their contribution to the overall cancer burden and regional disparities. Methods: We conducted a comprehensive analysis using 2022 GLOBOCAN

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… IntechOpen; Rijeka, Croatia: 2023. 46. He R., Jiang W., Wang C., Li X., Zhou W. Global burden of pancreatic cancer attributable to metabolic risks from 1990 to 2019, with projections of mortality to 2030. BMC Public Health. 2024;24:456. doi: 10.1186/s12889-024-17875-6. 47. …

Low-Bacterial Diet in Cancer Patients: A Systematic Review.

The low-bacterial diet (LBD) is a widely used dietary regimen to reduce the risk of food-borne infections in patients with neutropenic cancer, but its role is controversial due to its unclear benefits. The purpose of this study was to provide an updated analysis of the available evidence on the efficacy of the LBD to reduce the risk of infections, mortality rates, and quality of life (QoL) in neutropenic patients with cancer. A systematic literature search was conducted in the biomedical databases Cochrane Library, PubMed, CINHAL, and EMBASE. The process of the screening, selection, inclusion

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… Geographically, the studies were conducted in 27 countries, including the USA, the Netherlands, the Republic of Korea, mainland China, Italy, Spain, France, Germany, Turkey, the United Kingdom, Belgium, Poland, Switzerland, Australia, Algeria, Austria, Hungary, Croatia, the Czech Republic, Denmark, Greece …

Gaucher: A Systematic Review on Oral and Radiological Aspects.

Background and Objectives: Gaucher disease (GD) is a lysosomal storage disorder with the genetic autosomal recessive transmission. Bone involvement is a prevalent finding in Gaucher disease. It causes deformity and limits daily activities and the quality of life. In 75% of patients, there is bone involvement. This review aims to evaluate the principal findings in the jaw by a Cone-beam computed tomography (CBTC) and X-ray orthopantomography; Materials and Methods: PubMed, Web of Science, Lilacs and Scopus were systematically searched until 31 December 2022. In addition, a manual search was per

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… Interpretation of pulmonary function test results in relation to asthma classification using integrated software suite; Proceedings of the 36th International Convention on Information and Communication Technology, Electronics and Microelectronics (MIPRO 2013); Opatija, Croatia. 20–24 May 2013; pp. 140 …

The Reporting, Use, and Validity of Patient-Reported Outcomes in Multiple Myeloma in Clinical Trials: A Systematic Literature Review.

BACKGROUND: Patient-reported outcomes (PROs) are becoming increasingly important in supporting clinical outcomes in clinical trials. In multiple myeloma (MM), PRO measurement is useful to reveal how treatment affects physical, psychosocial, and functional behaviour as well as symptoms and treatment-related adverse events to evaluate the benefit-risk ratio of a particular drug or drug combination. We report the types of PRO instruments used in MM, the frequency in which they are utilised in randomised controlled trials (RCTs), and the consistency of their reporting. METHODS: The European Hemat

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… IntechOpen; Rijeka, Croatia: 2021. p. Ch. 2. 10. Durie B.G. New approaches to treatment for multiple myeloma: Durable remission and quality of life as primary goals. Clin. Lymphoma Myeloma. 2005;6:181–190. doi: 10.3816/CLM.2005.n.045. 11. …