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[Effect of different acupuncture and moxibustion methods on muscle inflammation and muscle atrophy related proteins in the gastrocnemius of rats with knee osteoarthritis].

OBJECTIVES: To compare the effects of filiform acupuncture, electroacupuncture (EA) and moxibustion on gastrocnemius inflammation and muscle atrophy related proteins in rats with knee osteoarthritis (KOA). METHODS: A total of 40 Wistar rats were randomly divided into blank control, model, filiform acupuncture, EA and moxibustion groups, with 8 rats in each group. The KOA model was established by intra-articular injection of sodium iodate into the right knee joint in the model group and treatment groups (filiform acupuncture, EA and moxibustion groups). Treatment groups received filiform acupu…

[Acupuncture mitigates ocular surface inflammatory response via α7nAChR/NF-κB p65 signaling in dry eye guinea pigs].

OBJECTIVE: To observe the effect of electroacupuncture (EA) on the ocular surface inflammation and α7 nicotinic acetylcholine receptor (α7nAChR) / nuclear factor kappa-B (NF-κB) p65 signal pathway in guinea pigs with dry eye, so as to explore its underlying mechanism. METHODS: A total of 32 male British tricolor short haired guinea pigs were randomized into blank control, model, EA and sham acupuncture groups, with 8 guinea pigs in each group. The dry eye model was established by subcutaneous injection of scopolamine hydrobromide solution (0.6 mg/0.2 mL each time, 4 times a day for 10 days). …

Integrative Medicine for Cancer-Related Pain: A Narrative Review.

Cancer-related pain (C-RP) is a prevalent and debilitating concern among patients with cancer, with conventional treatments limited in their ability to provide adequate relief, and by the adverse effects associated with their use. Complementary and integrative medicine (CIM) modalities have been shown to be potentially effective and safe for the treatment of pain and related symptoms, when used in conjunction with conventional medications and under medical supervision. An increasing number of oncology centers provide CIM within their conventional supportive and palliative care service, in an "

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… In today’s acupuncture practice, needles can be attached to electrodes from a 9-volt battery (“electroacupuncture”), for what is believed to be an enhanced effect. … In the Personalized Electroacupuncture vs. …

[Acupuncture and Chinese medicine of artificial cycle therapy for insulin resistance of polycystic ovary syndrome with phlegm damp type and its mechanism].

OBJECTIVE: To explore the effect difference between acupuncture combined with Chinese medicine of artificial cycle therapy on the basis of w … (CV 4) and Qihai (CV 6); Zhongji (CV 3) and Xuehai (SP 10) were matched in the ovulatory phase, and electroacupuncture were used at Qihai (CV 6) and Zhongji (CV 3), Xuehai (SP 10) and Yinlingquan (SP 9), 2 Hz and continuous wave; The acupoints in the luteal phase were the above main acupoints, at the same time, moxibustion was used at Guanyuan (CV 4) and Qihai (CV 6 …

Identification, pharmacologic considerations, and management of prostatitis.

BACKGROUND: Prostatitis is a collection of signs and symptoms that occur as a result of inflammation or swelling of the prostate gland. Ther … tment regimens may benefit from direct stimulation of the pelvic muscles through electromagnetic or electroacupuncture therapy. CONCLUSIONS: Prostatitis can resemble various other medical conditions but proper classification and an understanding of the pharmacologic features and expectations of the medications used to treat it can help identify effective treatment …

Investigating the Analgesic Mechanisms of Acupuncture for Cancer Pain: Insights From Multimodal Bioelectrical Signal Analysis.

PurposeCancer pain management remains a significant clinical challenge. While acupuncture has shown potential in alleviating cancer pain, its underlying mechanisms are not yet fully understood. This study investigates the neurophysiological mechanisms underlying acupuncture's analgesic effects using multimodal bioelectrical signal analysis.Patients and methodsFifteen cancer pain patients underwent acupuncture while wearing portable, multi-sensor devices to capture bioelectrical signals. Pain levels were assessed using the Numerical Rating Scale (NRS) before and during needle retention. Neuroph

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… This mechanism regulates the transmission of migraine pain signals from the periphery to the central nervous system. 18 This indicates that electroacupuncture’s analgesic effects are multifaceted, involving distinct physiological pathways at both cellular and neural levels. … Bioelectric phenomena in electroacupuncture analgesia . Zhongguo Zhen Jiu . 2023 ; 44 ( 1 ): 89 – 93 . 10.13703/j.0255-2930.20230413-0001 38191165 16. Lu K , Song X , Pan X , Wang Z , Guo H . …

Acupuncture Reduces Hypertrophy and Cardiac Fibrosis, and Improves Heart Function in Mice with Diabetic Cardiomyopathy.

PURPOSE: To assess the effects of electro-acupuncture (EA) on glycemic control, myocardial inflammation, and the progression of diabetic cardiomyopathy in mice with type 2 diabetes. METHODS: Db/Db mice received EA at PC6+ST36 (DM-Acu), non-acupoint simulation (DM-Sham), or no treatment (DM). EA was applied for 30 min per day, 5 days a week for 4 weeks. Heart function was assessed by echocardiography. Myocardium was assessed by RT-PCR, immunoblotting, and histology. Serum TNF-α, IL-1α, IL-1β, IL-6, and IL-8 were measured. RESULTS: DM-Acu, but not DM-Sham, reduced fasting blood glucose without

Acupuncture Synergized With Bortezomib Improves Survival of Multiple Myeloma Mice via Decreasing Metabolic Ornithine.

Multiple myeloma (MM) is a hematological malignancy worldwide in urgent need for novel therapeutic strategies. Since Velcade (bortezomib) was approved for the treatment of relapsed/refractory MM in 2003, we have seen considerable improvement in extending MM patient survival. However, most patients are fraught with high recurrence rate and incurability. Acupuncture is known for alleviating patient symptoms and improving the quality of life, but it is not well investigated in MM, especially in combination with bortezomib. In this study, we employed LC-MS and UHPLC-MS together with bioinformatics

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… The Effect of High and Low Frequency Electroacupuncture in Pain After Lower Abdominal Surgery. Pain (2002) 99(3):509–14. doi: 10.1016/S0304-3959(02)00261-0 22. Mavrommatis CI, Argyra E, Vadalouka A, Vasilakos DG. … Electroacupuncture for Thalidomide/Bortezomib-Induced Peripheral Neuropathy in Multiple Myeloma: A Feasibility Study. J Hematol Oncol (2014) 7:41. doi: 10.1186/1756-8722-7-41 42. Han X, Wang L, Shi H, Zheng G, He J, Wu W, et al. …

Acupuncture in Multiple Myeloma Peripheral Neuropathy: A Systematic Review.

BackgroundPeripheral neuropathy (PN) is a prevalent complication of multiple myeloma (MM), due to the disease itself or its treatment. Despite extensive research, the optimal treatment for multiple myeloma peripheral neuropathy (MMPN) remains unclear. Clinical practice has shown the potential efficacy of acupuncture in managing MMPN. This study aimed to conduct a comprehensive analysis of the literature to assess the effectiveness and safety of acupuncture as a treatment for MMPN.MethodsThe PubMed, Web of Science, MEDLINE, Cochrane Library, and Embase databases were comprehensively searched fr

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… Among the studies that used body acupuncture, one used electroacupuncture, 18 and the other used manual acupuncture. Table 2 The Details of the Intervention Protocol Abbreviation : N/R, Not reported. … Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study. J Hematol Oncol . 2014;7:41. doi: 10.1186/1756-8722-7-41 19. Bao T, Goloubeva O, Pelser C, et al. …

Исследования " горячих точек " и тенденций в области электрической стимуляции нарушений движения: библиометрический анализ на основе 2016 в адрес 2025.

Лечение электрической стимуляции стало важнейшим средством борьбы с нарушениями, связанными с движением. Однако быстро расширяющийся и фрагментированный объем литературы требует макроскопической оценки для выявления глобальных сетей сотрудничества и формирующихся научных границ. В связи с этим в рамках этого исследования был проведен всеобъемлющий визуализационный анализ исследовательских тенденций и " горячих точек " в этой области для определения эволюционной траектории и определения будущих терапевтических изменений. Публикации 2016 в адрес 2025 были найдены в Web of Science Core

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… Effects of electroacupuncture combined with hydrogel on the formation and changes in the glial scar in rats with spinal cord injury. J. Tradit. Chin. Med. Sci. 9, 197–205. doi: 10.1016/j.jtcms.2022.04.002 Kapadia N. M., Nagai M. … Electroacupuncture participates in pain transition through the KCC2/GABAAR pathway in the spinal dorsal horn of male rats. Acupunct. Herb. Med. 5, 217–228. doi: 10.1097/hm9.0000000000000161 Simon L., Alex P., Spencer N., Baltazar Z., Ludvic Z., Marwan H., et al. (2013). …

Progress and research trends in neurogenic bladder after spinal cord injury bibliometric analysis based on web of science database: An observational study.

Neurogenic bladder (NB) is a significant complication that often occurs after spinal cord injury. It results from urinary dysfunction caused by the injury, disrupting the normal neural control of the bladder and urethra. Symptoms of NB can include urinary frequency, urgency, incontinence, and retention, all of which can greatly impact the quality of life of affected individuals. While there are articles and reviews on NB, fewer specifically address NB following spinal cord injury. This study examined 1095 publications from January 1, 2000, to March 27, 2024, in the Web of Science core database

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… Electroacupuncture improves neurogenic bladder dysfunction through activation of NGF/TrkA signaling in a rat model. J Cell Biochem. 2019;120:9900–5. [26] Lin Q, Ren Y, Chen K, Duan H, Chen M, Liu C. … Effects of electroacupuncture on bladder and bowel function in patients with transverse myelitis: a prospective observational study. Acupunct Med. 2018;36:261–6. [28] Peyronnet B, Roumiguié M, Castel-Lacanal E, et al. …

Physiotherapy for pain and disability in adults with complex regional pain syndrome (CRPS) types I and II.

BACKGROUND: Complex regional pain syndrome (CRPS) is a painful and disabling condition that usually manifests in response to trauma or surge … s including physical rehabilitation, electrotherapy modalities, cortically directed rehabilitation, electroacupuncture and exposure-based approaches. Most interventions were tested in small, single trials. Most were at high risk of bias overall (27 trials) and the remainder were at 'unclear' risk of bias (seven trials). For all comparisons and outcomes where we foun …

[Biomechanical mechanism of acupotomy on cartilage degeneration in KOA rabbits based on three-dimensional finite element model].

OBJECTIVE: To observe the effect of acupotomy on cartilage degeneration in rabbits with knee osteoarthritis (KOA) from the perspectives of force line and knee joint stress distribution, and to explore the biomechanical mechanism of acupotomy for KOA. METHODS: A total of 24 male New Zealand rabbits were randomly divided into a normal group, a model group, an electroacupuncture (EA) group and an acupotomy group, 6 rabbits in each group. Except for the normal group, in the other 3 groups, the left hind limbs were immobilized for 6 weeks to establish KOA model using the modified Videman method. I…

A randomized exploratory phase 2 study in patients with chemotherapy-related peripheral neuropathy evaluating whole-body vibration training as adjunct to an integrated program including massage, passive mobilization and physical exercises.

BackgroundChemotherapy-induced polyneuropathy (CIPN) is a common toxicity after chemotherapy, immunomodulatory drugs or proteasome inhibitors, which is difficult to treat and may also have impact on quality of life. The objective of the study was to evaluate whole-body vibration (WBV) on the background of an integrated program (IP) including massage, passive mobilization and physical exercises on CIPN.Patients and methodsIn an exploratory phase-2 study patients with CIPN (NCI CTC grade 2/3) were randomized for WBV plus IP (experimental) to IP alone (standard). 15 training sessions within 15 we

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… Treatment with electroacupuncture may be a therapeutic strategy for CIPN in patients with multiple myeloma. However, a randomized study is currently not available to confirm the results of the reported small phase-II study [ 14 ]. … Interestingly, electroacupuncture also showed an improvement of CIPN measured with the FACT/GOG-NTX scale [ 14 ]. …

[Effect of "Xingnao Kaiqiao" needling on expression of ferroptosis-related factors in rats with cerebral ischemia-reperfusion injury].

OBJECTIVES: To observe the effect of "Xingnao Kaiqiao" needling on the expression of ferroptosis-related proteins in neurons of rats with ce … ao" needling was applied to "Shuigou" (GV26), "Neiguan" (PC6) and "Sanyinjiao"(SP6) for 20 min with electroacupuncture (2 Hz/15 Hz, 1 mA) at PC6 and SP6, twice daily for continuous 3 days. Rats of the DFO group received intraperitoneal injection of iron chelator DFO (0.1 g/kg, once daily). The severity of neurological impairment (neurological deficit score, 0-5 poin …

[Effect of moxa-cone moxibustion at lung's back-shu points and front-mu points on Th17/Treg balance in mice with asthma].

OBJECTIVE: To observe the effect of moxa-cone moxibustion at lung's back-shu points and front-mu points on the expression of helper T lymphocyte 17 (Th 17)/regulatory T lymphocyte (Treg) in mice with asthma, and to explore the possible mechanism of moxa-cone moxibustion on asthma. METHODS: Sixty SPF-grade healthy male Balb/c mice were randomly divided into a normal group, a model group, an LY294002 group (LY group), an electroacupuncture (EA) group and a moxibustion group, 12 mice in each group. Asthma model was replicated by using ovalbumin (OVA) sensitization. Except the mice in the normal …

[Catheter balloon dilation combined with acupuncture for cricopharyngeal achalasia after brain stem infarction: a randomized controlled trial].

OBJECTIVE: To screen the optimal acupuncture regimen for cricopharyngeal achalasia (CPA) after brain stem infarction and compare the therape … ints in accordance with the syndrome differentiation. In the group C1 and group C2, after deqi, the electroacupuncture was used, with continuous dense wave, 5 to 8 Hz in frequency. The needles were retained for 30 min. Acupuncture was given once a day, 5 treatments a week. Before treatment, in 6 weeks of treatment or after removal of gastric tube, the rehabilitation …

Traditional chinese medicine in cancer care: a review of case series published in the chinese literature.

Traditional Chinese medicine (TCM) has been widely used in cancer in China. Case series report a series of cases exposed to a certain intervention. To understand the current situation of case series of TCM for cancer, we performed this review. We included case series of cancer patients treated with TCM therapy. Electronic searches were conducted in four main Chinese databases until February 2011. A total of 1,217 reports of case series (92,945 patients) were included. The top five types of cancer were lung cancer, liver cancer, stomach cancer, leukemia, and esophageal cancer. Leukopenia and hi

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… Acupoint stimulation was further classified into manual acupuncture, moxibustion, ear-acupuncture, cupping, electroacupuncture, and acupuncture point injection (injection with western medicine was defined as integrated therapy). … Types of acupoint stimulation mainly involved manual acupuncture, acupuncture point injection, and electroacupuncture ( Table 3 ). …

A comprehensive review on pain: Model, target, therapy, and prospect (Review).

Pain serves as both a protective physiological response essential for species survival and a global health issue affecting human well‑being and societal development. The present review systematically summarized and analyzed the research progresses on pain through a multidimensional analytical framework encompassing animal models, molecular targets, therapeutic approaches and future prospects. In animal modeling, neuropathic pain paradigms have evolved from traditional mechanical compression to composite models that combine dynamic displacement and chemical stimulation. Cancer‑induced pain mode

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… The model also facilitates analgesic intervention evaluation: Electroacupuncture attenuated pain via autophagy-mediated NLRP3 suppression or NRG1/ErbB2 signaling modulation of glial activation, while opioids paradoxically promoted tumor angiogenesis through μ opioid receptor (MOR) upregulation. … Previous studies confirmed electroacupuncture combined with spinal orphanin FQ receptor antagonists modulates such pain, validating acupuncture analgesia in chronic inflammation ( 110 , 111 ). …

["Shugan Tiaoshen" acupuncture improves chronic inflammatory pain and depression comorbidity by inhibiting ferroptosis of hippocampal neurons].

OBJECTIVES: To observe the effect of "Shugan Tiaoshen" (regulating mental activities by relieving depressed liver) acupuncture on hippocampal iron metabolism, antioxidant system and lipid peroxidation related factors in chronic inflammatory pain and depression comorbidity (CIPDC) rats and its protective effect on hippocampal neurons, so as to explore its mechanisms underlying improvement of CIPDC. METHODS: A total of 48 male SD rats were randomly divided into control, model, electroacupuncture (EA) and medication (paroxetine) groups, with 12 rats in each group. The CIPDC model was established…