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The DMP atlas for North Rhine-Westphalia, Germany: results of the disease management programmes on district level.

Disease Management Programmes (DMP) in Germany were initiated to enhance the quality of ambulatory health care for specific chronic diseases. They aim to prevent the progression of the disease and comorbidity as well as to improve quality of life. It is the purpose of this paper to describe the contents of the web-based DMP atlas for North Rhine-Westphalia. The atlas provides a comprehensive overview of the regional DMP results, including outcomes at district level. In 2024, these analyses encompassed data of approximately 1.8 million patients. Quality of care is displayed by quality indicator…

Baby Boomers in Germany: a secondary data analysis of demographics, regional disparities, healthcare utilization, and mortality.

BACKGROUND: The demographic shift driven by the aging Baby Boomer cohort represents a substantial burden for our healthcare system. The aim … stics. RESULTS: At the end of the Baby Boomers’ birth period, the registered resident population in Germany born between 1955 and 1969 was 18.20 million. Most Baby Boomers live in cities, metropolitan areas or in North Rhine-Westphalia, eastern Germany, and Baden-Württemberg. The relative share of the population clearly shows a statistically significant u …

Ecological momentary insights into cannabis use and its contexts: a pre-post legalization study in Germany.

Globally, cannabis ranks third in psychoactive substance prevalence after nicotine and alcohol, with heavy use linked to psychosis, anxiety, and depression. However, real-time data on how legal reforms influence consumption remain scarce. This Ecological Momentary Assessment (EMA) study analyzed daily cannabis use patterns before and after Germany's recreational cannabis decriminalization in April 2024 in 49 individuals (34.7% women, age 33.8 ± 11 years). Following the legal reform, a selective increase in consumed amounts among younger individuals (β = 0.01, 95%CI = 0.00-0.02, z = 3.05) was o…

[Real-world Management of Acute Pancreatitis in Germany - Results of a Nationwide Survey Among Gastroenterology Hospitals].

BACKGROUND: There are no current data on real-world management of acute pancreatitis in German hospitals. The ALGK (Working Group of Leading … s recommend referral to specialized lipid clinics. CONCLUSION: Management of acute pancreatitis in Germany shows gaps in implementing S3 guideline recommendations. Standardized protocols and improved follow-up concepts could enhance quality of care and reduce recurrence rates.

Evaluation of Morphological and Osteometric Sex Estimation on Historical Skeletal Material of Subadult Individuals From Germany.

OBJECTIVES: While sex estimation based on morphological features of the adult skeleton is considered reliable, it proves to be challenging, especially in skeletons of subadults. The purpose of this study is to investigate the accuracy of sex estimation of the methods described below and errors within the observer and between observers. MATERIALS AND METHODS: For this purpose, samples from 20 individuals from four different skeleton series from Lower Saxony (Germany) were analyzed. DNA-analytical examinations were used for sex determination. The primary aim was to validate the morphological an…

Burden of hidradenitis suppurativa in Germany: a retrospective claims data analysis and comparison with non-HS patients.

BACKGROUND: The aim of this analysis was to assess the burden of hidradenitis suppurativa (HS) in Germany. PATIENTS AND METHODS: This was a retrospective German statutory health insurance claims data analysis covering the years 2020-2022 and 4.1 million individuals. An HS prevalence cohort and matched non-HS cohort representing the general population were analyzed regarding burden of disease indicators. An HS incidence cohort was analyzed regarding flare occurrences. RESULTS: Adult HS patients showed a significantly higher prevalence of comorbidities including a 3.58 (95% CI: 3.30; 3.85) hig…

Interplay of Atrial Arrhythmia and Chronic Heart Failure: A Population-Based Analysis of Hospital Outcomes in Germany.

AIMS: Atrial fibrillation or flutter (AFl) frequently coexists with chronic heart failure (CHF), yet its impact on in-hospital outcomes in large, unselected populations remains insufficiently defined. METHODS: We analyzed all hospitalizations for CHF (ICD-10-GM I50*) in Germany from 2014 to 2022 using nationwide administrative data. Patients were stratified by rhythm status (AFl vs. non-AFl). Outcomes included in-hospital mortality, complications, length of stay, and health care costs. Multivariable logistic regression was used to identify independent predictors of mortality. RESULTS: Among …

(Alzheimer's) dementia in adults with Down syndrome in Germany: Administrative prevalence based on a claims data analysis.

BackgroundPeople with Down syndrome (DS) have a significantly increased risk of developing early-onset Alzheimer's disease. For example, a l … epidemiological data. This suggests a potential underdiagnosis of dementia in the DS population in Germany.

Current Practices and Perspectives on Video Capsule Endoscopy in Germany: Findings from a nationwide survey of gastroenterologists.

BACKGROUND AND STUDY AIMS: Video capsule endoscopy (VCE) is an established approach for small bowel (SB) examination. In 2022, the European Society of Gastrointestinal Endoscopy (ESGE) updated its guideline on VCE use. However, little is known about guideline implementation in daily clinical practice. METHODS: Between June and August 2025, we performed a nationwide online survey on VCE use in Germany. A questionnaire was distributed to gastroenterologists in Germany performing VCE in in- or outpatient settings. RESULTS: The main indications for VCE were SB bleeding and iron deficiency anaemi…

Misophonia in a large treatment-seeking child and adolescent sample in mental health care in Germany and Austria.

BACKGROUND: Misophonia is a newly conceptualized disorder. Although its onset is usually in childhood and early adolescence, the current knowledge about etiology or treatment options for children and adolescents is still limited. This is the first study investigating treatment-seeking children and adolescents in routine mental health care with regard to misophonia symptomatology and co-occurring symptoms. METHODS: In this multi-center cross-sectional study, conducted in Germany and Austria, N = 214 participants completed measures on misophonia, anxiety, depression, posttraumatic stress disorde…

Molecular Identification and Phenotypic Antimicrobial Resistance of Acinetobacter spp. from an Equine University Clinic in Germany.

BACKGROUND: While equine patient-mediated introduction of A. baumannii into hospital settings has been documented, its environmental dissemination and the risk of hospital-acquired surgical site infection remain poorly understood. OBJECTIVE: Therefore, this descriptive observational study examined (a) the environmental distribution of Acinetobacter spp. in an equine university hospital, (b) the impact of the implementation of new hygiene protocols, (c) the specification of resistance patterns, and (d) the evaluation of the presence of Acinetobacter spp. in hospital-acquired wound infections.

Surveillance of invasive pneumococcal disease in Germany: surge in PCV13 serotypes and new challenges, 2017 to 2024.

BACKGROUNDPneumococcal vaccination has been recommended in Germany for adults aged ≥ 60 years (1998) and children aged < 2 years (2006), resulting in a reduction of pneumococcal disease incidence in vaccinated children and unvaccinated individuals through herd protection.AIMWe aimed to investigate serotype distribution of invasive pneumococcal disease (IPD) among children and adults in 2017-2024.METHODSWe analysed data of an ongoing nationwide surveillance of IPD. All isolates were serotyped by Neufeld's Quellung reaction.RESULTSIn total, 24,122 IPD isolates were analysed by the German Referen…

Стационарная помощь лицам с множественным склерозом - вторичный анализ данных в Германии между 2019 и 2024.

Множественный склероз (MS) является хроническим аутоиммунным заболеванием, которое ложится тяжелым бременем на системы здравоохранения. В Германии услуги по уходу за больными переходят от стационарного лечения к амбулаторному лечению, чему способствуют успехи в лечении заболеваний и развитие инфраструктуры ухода. Всесторонние данные о тенденциях использования стационаров и их детерминантах по-прежнему ограничены. ЦЕЛИ: Анализ практики госпитализации и приема в детские сады лиц, имеющих MS (PWMS) в Германии в период между 2019 и 2024, анализ тенденций в разбивке по подтипам заболеваний, демогра

Совпадение в аннотации оригинала
BACKGROUND: Multiple sclerosis (MS) is a chronic autoimmune disease imposing a substantial burden on healthcare systems. In Germany, MS care has been transitioning from inpatient to outpatient settings, driven by advances in disease-modifying therapies and evolving care infrastructure. Comprehensive data on inpatient utilisation trends and their determinants…

Long-Term Cost and Health Impact of a Digital Obesity Intervention in Germany: Economic Modeling Study.

BACKGROUND: Obesity imposes a substantial economic burden, accounting for an estimated 10% of total health care expenditures in Germany. Digital health apps (DHAs) have demonstrated effectiveness in supporting weight management among individuals with obesity; however, evidence regarding their long-term economic impact remains limited. OBJECTIVE: This study aimed to evaluate the long-term cost-effectiveness of the Oviva Direkt app for obesity treatment in the German health care context. METHODS: We developed a cohort-based Markov model, informed by the Core Obesity Model, to evaluate the cost…

Caries experience and care in Germany: results of the 6th German Oral Health Study (DMS • 6).

OBJECTIVES: One goal of the 6th German Oral Health Study (DMS • 6) was to survey the caries experience and care for caries in a representative cross-sectional study across Germany. METHOD AND MATERIALS: Using almost the same methodology as the previous studies DMS III (1997) to V (2014), data were collected on caries experience (including dmft/DMFT, root caries) in the three standard World Health Organization age groups (12-year-olds, 35- to 44-year-olds, and 65- to 74-year-olds) as well as among 8- and 9-year-olds. RESULTS: The caries experience expressed as dmft/DMFT in 8- and 9-year-olds …

[White paper on identification, information, and eligibility assessment of potential participants in lung cancer screening in Germany].

The nationwide introduction of lung cancer screening using low-dose computed tomography (LDCT) is imminent in Germany. In contrast to other cancer screening programs, lung cancer screening follows a risk-based approach and specifically targets heavy current and former smokers aged 50 to 75 years. Following several years of pilot phases and regulatory preparation, the Federal Joint Committee (G-BA) decided in June 2025 to include this program as a regular benefit covered by statutory health insurance starting in 2026.Evidence from large international studies demonstrates a significant reduction…

Determinants of the number of dental visits in the general adult population in Germany during the COVID-19 pandemic.

BACKGROUND: Oral health is essential to general health and well-being. The utilization of oral health care services represents an important factor in reducing oral health morbidities. In order to understand the disparities in the frequency of dental visits, it is necessary to identify determinants that influence the use of those services. The aim of the current study was to investigate the determinants of the number of dental visits in Germany during the COVID-19 pandemic. METHODS: We used data from the general adult population in Germany with n = 2,807 individuals in the analytical sample. A…

The public health impact of the Rx-to-OTC switch of triptan in Germany: Systematic review and framework analysis.

BACKGROUND: Migraine is a prevalent and debilitating condition in Germany, affecting 10%-15% of the population. Triptans are the primary treatment for acute attacks. The switch of triptans from prescription (Rx) to over-the-counter (OTC) status in Germany aims to improve access and timely treatment. However, it also raises concerns regarding patient safety and misuse. The public health impact of the triptan Rx-to-OTC switch remains underexplored. This study aims to evaluate the public health implications of the Rx-to-OTC switch of triptans in Germany. OBJECTIVES: Evaluate the public health im…

Vitamin D Levels in Patients Presenting to a Rheumatology Clinic in Germany: Associations with Patient Characteristics and Season.

Background: High rates of vitamin D deficiency have been reported in population-based studies, including those conducted in Germany. The goal of this study was to evaluate vitamin D levels and associated factors in a clinical cohort of German patients presenting to a rheumatology clinic. Methods: We conducted a retrospective observational study of electronic health record data from patients presenting to a rheumatology clinic in southern Germany. Data included demographic characteristics and vitamin D levels as measured by the Elecsys® Vitamin D total III assay (Roche). Associations between vi…

Temporal trends in the prescription of low-dose antithrombotic and anti-inflammatory therapies in Germany (2022-2024).

AIMS: This study aimed to investigate the prescription rates of low-dose antithrombotic and anti-inflammatory therapies in Germany from 2022 to 2024. METHODS: We analyzed national outpatient claims data from the German Institute for Drug Use Evaluation. Claims data for patients receiving the following medications were included: aspirin 100 mg, clopidogrel 75 mg, prasugrel 5 mg and 10 mg, ticagrelor 60 mg and 90 mg, rivaroxaban 2.5 mg, and colchicine 0.5 mg. Drug utilization was quantified using defined daily doses per 1000 Statutory Health-insured persons per day (DID, 10 DID = approximately …