Результаты поиска

A two-tier polymerase chain reaction direct sequencing method for detecting and typing human papillomaviruses in pathological specimens.

An in-house polymerase chain reaction direct sequencing (PCR-DS) approach for HPV detection and typing was developed, taking advantage of two widely used pairs of human papillomavirus (HPV)-specific PCR primers, MY09/MY11 and GP5/GP6, and 33P-labeled dideoxynucleotides. In this study, 105 pathological specimens were examined: 89% were diagnosed as cervical intraepithelial neoplasia (CIN) grade I-III, 76.2% were HPV-positive by PCR-DS. The PCR using GP5/GP6 (first tier) and MY09/MY11 primers (second tier for the GP5/GP6-negative samples) detected additional 15%-25% HPV-positive samples compared

Metatarsal metastasis from clear cell renal cell carcinoma: a case report and literature review.

BACKGROUND: Bone metastasis is known to occur in some patients with cancer, usually in the spine, pelvis or ribs, and less than 0.01% of patients have metastases in the foot bone, so metatarsal metastasis is quite rare. The initial symptoms of osseous metastases are swelling, pain, or both. CASE PRESENTATION: We report a 68-year-old man with solitary metatarsal metastasis 26 months after a diagnosis of renal clear cell carcinoma. The patient suffered intermittent swelling of his right foot and pain for one year due to trauma and was not treated. The doctor attributed the symptoms to trauma, a

Совпадение в полном тексте источника
… metatarsal bone Fig. 5 Postoperative X-ray scan of the patient. a Positive radiograph. b Lateral radiograph Discussion and conclusion RCC is commonly known to metastasize to the lungs, bone, and brain, but RCC can metastasize to some atypical sites as well, such as skeletal muscle [ 4 ], scalp [ 5 ] and uvula … Atypical metastasis of renal cell carcinoma to the uvula: case report and review of literature. Int Med Case Rep J. 2018;11:29–32. doi: 10.2147/IMCRJ.S147815. 7. Kemnitz MJ, Erdmann BB, Julsrud ME, Jacobs PM, Ringstrom JB. Adenocarcinoma of the lung with metatarsal metastasis. …

Causal Beliefs Affect Treatment Practices and Preferences for Neonatal Danger Signs in Northwest Ethiopia: A Qualitative Study.

This study was conducted to explore the experiences of community members, particularly mothers, concerning their beliefs about the causes, treatment practices, and preferences for World Health Organization-defined neonatal danger signs in northwest Ethiopia. A phenomenological qualitative study was conducted in three districts of north Gondar Zone, Amhara region, Ethiopia, from March 10 to 28, 2016. Twelve focus group discussions were conducted involving 98 individuals. In-depth interviews were conducted with six health extension workers and 30 women who were either pregnant or who delivered i

Modified uvulopalatopharyngoplasty and coblation channeling of the tongue for obstructive sleep apnea: a multi-centre Australian trial.

STUDY OBJECTIVES: To investigate the surgical outcomes and efficacy of modified uvulopalatopharyngoplasty (mod UPPP) and Coblation channelling of the tongue (CCT) as a treatment for obstructive sleep apnea (OSA). METHODS: Adult patients with simple snoring or obstructive sleep apnea were treated with combined modified UPPP, bilateral tonsillectomy, and CCT (N = 48). Full polysomnography was performed preoperatively and 3 months postoperatively. Postoperative clinical assessment, sleep questionnaires, and patient demographics including body mass index were compared to preoperative data. All po

Vessel sealing system uvulopalatoplasty versus uvulopalatal flap: a randomized, controlled study of efficacy and adverse effects.

The objective of this randomized, controlled study is to compare intraoperative blood loss, operative time, postoperative pain and postoperative adverse effects (bleeding, velopharyngeal insufficiency and others) between vessel sealing system uvulopalatoplasty (VSSU) and uvulopalatal flap (UPF). The study was conducted at the Department of Otolaryngology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand. 31 subjects with sleep-disordered breathing and obstruction at the retropalatal level were enrolled consecutively. Intervention was randomized by mixed block randomization into 2 groups

Cervical CT derived neck fat tissue distribution differences in Japanese males and females and its effect on retroglossal and retropalatal airway volume.

OBJECTIVE: The objective of this study was to investigate the difference of neck fat tissue distribution by sex and its correlation with retropalatal and retroglossal airway. STUDY DESIGN: A total of 38 consecutive patients (male: 19; female: 19) who received a CT scan were compared in the retroglossal region and at the narrowest cross section of the airway. Retroglossal fat tissue volume (FV) was segmented with Amira software and separated into subcutaneous and internal fat volume (SFV, IFV). These volumes were normalized by retroglossal neck volume (NV). RESULTS: Men had 51.9% more IFV/NV

Pycnodysostosis at otorhinolaryngology.

AIM: Pycnodysostosis is a rare autosomal, recessive, skeletal dysplasia caused by a mutation in the cathepsin k gene. Pycnodysostosis is cha … three (37.5%) patients displayed grade 1 Mallampati score. Further, while six (75%) patients had no uvular pathology, one (12.5%) patient presented with uvular elongation and another patient had a bifid uvula. Cephalometric measurements such as PAS-UP (mean 5.67 mm; range: 5.0-7.6 mm) and PAS-TP (mean 9.61 mm; range: 8.5-12.2 mm) were lower than that of …

Assessment of ED triage of anaphylaxis patients based on the Emergency Severity Index.

OBJECTIVES: To describe the emergency department (ED) triage of anaphylaxis patients based on the Emergency Severity Index (ESI), assess the … hrine from emergency medical services (OR 0.56 [0.38-0.82]), presented with posterior pharyngeal or uvular angioedema (OR, 0.56 [0.38-0.82]), hypoxemia (OR, 0.34 [0.18-0.64]), or increased heart (OR 0.83 [0.73-0.95]) or respiratory (OR 0.70 [0.60-0.82]) rates. CONCLUSION: Patients triaged to lower acuity ESI levels experienced delays in ED epinephrine …

The incidence of early post-operative complications following uvulopalatopharyngoplasty: identification of predictive risk factors.

OBJECTIVE: Characterize complications following uvulopalatopharyngoplasty (UPPP) for obstructive sleep apnea. STUDY DESIGN: Retrospective chart review. SUBJECTS AND METHODS: Charts of patients undergoing UPPP at an academic teaching hospital from 1999 to 2005 were reviewed. RESULTS: 345 consecutive patients (248 inpatients; 97 outpatients) were studied. The most common post-operative complication in the entire study was oxyhemoglobin desaturation (12.8%). Three patients suffered major complications (airway obstruction, pulmonary edema, arrhythmia). Regarding complications limited to the pos

Traditional nutritional and surgical practices and their effects on the growth of infants in south-west Ethiopia.

A 1-year birth cohort of 1563 infants was seen bi-monthly for the first year of life. They comprised all identified infants born in Jimma town, south-west Ethiopia, in the year starting 1 Meskren 1985 in the Ethiopian calendar (11 September 1992). Growth in infancy is poor in this town, as it is in Ethiopia more generally: mean z-scores for both weight and length were more than 1.5 SD below the median of the NCHS/WHO reference population by 1 year of age, and infant mortality was 115/1000. In this paper we examine the weight gain of singletons in relation to background variables and to traditi

Different therapeutic mechanisms of rigid and semi-rigid mandibular repositioning devices in obstructive sleep apnea syndrome.

To clarify the mechanisms of rigid and semi-rigid mandibular repositioning devices (MRDs) in obstructive sleep apnea syndrome (OSAS), seven … d in the respective groups (P < 0.05). However, airway volume, cross-sectional area measured at the uvular tip level, and anteroposterior and transverse diameters of the airway were not significantly different. In conclusion, both types of MRDs improve respiratory status, but they affect different parts of the airway.

Seroprevalence of Hepatitis B Infection in Nigeria: A National Survey.

Hepatitis B virus (HBV) infection accounts for about 1 million deaths worldwide annually. This study was to determine the prevalence, distribution of HBV, and factors associated with infection in an apparently healthy population in Nigeria. A cross-sectional study among the general population was conducted employing a multistage sampling technique. Data on demographic, social, and behavioral indicators were collected using questionnaires and blood samples tested for HBV seromarkers. Descriptive, bivariate, and multivariate analyses were done. Prevalence of hepatitis B infection was 12.2% (conf

Brachytherapy versus surgery in carcinoma of tonsillar fossa and/or soft palate: late adverse sequelae and performance status: can we be more selective and obtain better tissue sparing?

PURPOSE: To report on the tumor control, adverse late normal tissue sequelae, and functional performance in patients with tonsillar fossa an … ry to treat the contralateral neck, unless the tumor extends beyond the midline of the soft palate (uvula) or beyond the lateral one-third of the ipsilateral base of the tongue. Moreover, with the currently available CT-based neck level definitions, more conformal contours (i.e., tighter boundaries) around the clinical target volume can be designed. In …

Coexistence of Autoantibodies against the Golgi Complex and Ro52 Antigen in a Patient with Nonspecific Interstitial Pneumonia.

Nonspecific interstitial pneumonia (NSIP) is often associated with connective tissue diseases (CTD). The diagnosis of NSIP was confirmed in a 63-year-old man by high-resolution computed tomography and an open lung biopsy. Anti-Golgi complex autoantibodies (AGA) and anti-Ro52 antibodies were simultaneously detected at high concentrations. Autoantibodies to aminoacyl-tRNA synthetases (ARS) were negative. The patient was treated with corticosteroids for six months. During the seven-year follow-up, NSIP had a slow progression and patient had not developed the clinical features of CTD. The present

A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity.

BACKGROUND/PURPOSE: Oral involvement often constitutes the first sign of amyloidosis as a life-threatening disease that can lead to multiple organ impairment. The purpose of this study was to analyze the scientometric characteristics and research trends of amyloidosis involving the oral cavity. MATERIALS AND METHODS: All the papers on oral involvement of amyloidosis were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2015 and 2015-2024 in the analysis of research trends. RESULTS: There were 2540 relevant papers on amyloidosis involving t

Совпадение в полном тексте источника
… Uvula amyloidosis. N Engl J Med. 2020;383:577. doi: 10.1056/NEJMicm1915258. 11. Sanchorawala V. Systemic light chain amyloidosis. N Engl J Med. 2024;390:2295–2307. doi: 10.1056/NEJMra2304088. 12. Adams D., Koike H., Slama M., Coelho T. …

Эксклюзивный метастаз желчного протока в множестве миеломы: доклад о деле и обзор литературы.

Внешняя миелома (ЕММ) определяется проникновением злокачественных плазменных клеток в неопасные ткани. Его соучастие с илар-холангиокарсином остается чрезвычайно редким явлением. Такая диагностика сопряжена с существенными клиническими рисками, поскольку неправильное отнесение ЭММ к категории билиарной карциномы может привести к неправильному хирургическому вмешательству и задержкам с системной терапией, что в конечном счете поставит под угрозу выживание пациента. Поэтому мы сообщаем об этом случае неправильного диагноза, с тем чтобы снизить коэффициент неправильного диагностирования в будущем

Совпадение в полном тексте источника
… World J Surg Oncol 2025 ; 23 : 210 . 10.1186/s12957-025-03851-w 40450260 PMC12126908 5 Yang J Peng H Tu SK Extramedullary plasmacytoma with the uvula as first affected site: A case report. …

Peritonsillar Abscess Simulator: A Low-Cost, High-Fidelity Trainer.

AUDIENCE: Our reusable low-cost peritonsillar abscess simulator (PTA) simulator is designed to train emergency medicine (EM) residents, fell … nsillectomy.The simulator provides a realistic characteristic of typical PTA presentations, such as uvula deviation, swelling, trismus, and purulence during aspiration. While learning to drain a PTA, trainees must locate the infection with a needle without injury to the surrounding structures of the oral cavity and deep structures of the neck. The disco …

[Dysphagia or dysphagias during neuroleptic medication?].

INTRODUCTION: Dysphagia is a common symptom in the general population, and even more among psychiatric patients, but rarely seen as a sign o … w physical examination is performed; it is normal except for sedation and a slight deviation of the uvula. Upper gastrointestinal endoscopy shows no anatomical lesion. No functional assessment of swallowing is done however. At this stage, the suspicion of neuroleptic induced dysphagia appears to be the most likely hypothesis. Treatment with loxapine is …

Ensuring the Safety of Yellow Fever Vaccination in Travelers-The Experience at a Large U.S. Academic Medical Center in Colorado.

Background: Yellow fever (YF) virus has the potential to cause fatal outcomes among at-risk individuals visiting endemic areas. Vaccinating travelers who are at risk is necessary to prevent virus-related life-threatening complications. We lack data on the clinical features of persons seeking YF vaccination. We aim to describe the characteristics of a cohort of persons receiving the YF vaccine before travel. Methods: A retrospective analysis of 964 travelers receiving the YF vaccine (Stamaril®) from Oct 2016 to Jul 2019 was performed at the University of Colorado Hospital, U.S. Percentages, mea

Совпадение в полном тексте источника
… CM | 173.99 | Sweat gland tumor, malignant | Neoplasms ICD-9-CM | 172.9 | Superficial spreading melanoma (HC code) | Neoplasms ICD-10-CM | D25.2 | Subserosal leiomyoma of uterus | Neoplasms ICD-9-CM | 154.1 | Stage IV carcinoma of rectum (HC code) | Neoplasms ICD-9-CM | 210.4 | Squamous papilloma of uvula …