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'It gives you an understanding you can't get from any book.' The relationship between medical students' and doctors' personal illness experiences and their performance: a qualitative and quantitative study.

BackgroundAnecdotes abound about doctors' personal illness experiences and the effect they have on their empathy and care of patients. We formally investigated the relationship between doctors' and medical students' personal illness experiences, their examination results, preparedness for clinical practice, learning and professional attitudes and behaviour towards patients.MethodsNewly-qualified UK doctors in 2005 (n = 2062/4784), and two cohorts of students at one London medical school (n = 640/749) participated in the quantitative arm of the study. 37 Consultants, 1 Specialist Registrar, 2 C

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… It may be that the medical students who reported higher levels of state anxiety were also higher on the personality trait neuroticism [ 40 ]. High neuroticism individuals tend to be more anxious [ 41 ] and report more illness symptoms [ 41 ]. … Perhaps students who reported being ill were not more anxious because they were ill, but remembered more illness and were more anxious because they were higher on neuroticism . …

A Shared Genetic Basis Underlying Myopia-Exotropia Comorbidity.

IMPORTANCE: Adolescent depression is characterized by diverse symptom trajectories over time and has a strong genetic influence. Research ha … h mixture modeling of longitudinal depression symptoms. PRSs were computed for depression, anxiety, neuroticism, bipolar disorder, schizophrenia, attention-deficit/hyperactivity disorder, and autism in European ancestry. Genomic structural equation modeling was used to build multitrait genetic models of psychopathology followed by multitrait PRS. Depression P …

[Psychological features of primary Sjögren syndrome].

Összefoglaló. A primer Sjögren-szindróma (pSS) krónikus autoimmun betegség, melynek elsődleges tünetei az exokrin mirigyeket érintő autoimmu … kre is, amely ígéretes terület, de kevés adat áll rendelkezésünkre; az eddigi vizsgálatok alapján a neuroticismus a leginkább pSS-re jellemző tényező. A kognitív funkciók érintettségének összefoglalása és az egyéb pszichológiai tényezők (szellemi fáradtság, szexualitás, testképzavar, életminőség) összegzése után egyértelműen levonható a következtetés, hogy a …

Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder.

IMPORTANCE: Antidepressant treatment remains a trial-and-error process: one-third of people with major depressive disorder (MDD) report inef … CI, 0.02-0.05; P = 2.1 × 10-5 ; bipolar disorder PGS: β, 0.03; 95% CI, 0.01-0.04. P = 1.2 × 10-4 ; neuroticism PGS: β, 0.02; 95% CI, 0.01-0.04; P = 1.3 × 10-3). A total of 5453 (61%) met criteria for an exclusive antidepressant sustained-use 360 group. These groups had distinct phenotypic profiles, including associations with body mass index, suicidal ideati …

Information-Seeking Patterns and Communication Preferences Among Japanese Survivors With Cancer: Cross-Sectional Analysis.

BackgroundWith increasing numbers of survivors with cancer, the importance of patient-centered information provision and communication to alleviate psychological burdens, such as anxiety and depression, is growing. However, substantial individual differences exist in patients with cancer information-seeking behaviors and use of support services, and few studies have comprehensively examined cognitive and psychological factors such as treatment status, sex, trust in information sources, and patient-provider relationships.ObjectiveThis study aimed to integrate the theory of planned behavior and

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… The TIPI-J measures the Big Five personality dimensions—extraversion, agreeableness, conscientiousness, neuroticism, and openness—with 2 items each and has shown high internal consistency: extraversion (α=.92), agreeableness (α=.85), conscientiousness (α=.82), neuroticism (α=.91), and openness (α=.86 … Regarding the TIPI-J, agreeableness ( χ ² ₂ =6.7; P =.04) and neuroticism ( χ ² ₂ =8.8; P =.01) did not show significant differences after the post hoc test ( Figure 4 and Multimedia Appendix 2 ). Figure 3. …

Теоретический опыт в множестве склерозов: функциональные неврологические симптомы, недовольство изображением тела и расстройство пищевой практики. Обзор описательной части.

Множественный склероз (MS) — хроническое заболевание центральной нервной системы, связанное с целым рядом физических, когнитивных и психологических трудностей. Помимо классических неврологических симптомов, нарушения физического опыта, включая функциональные неврологические симптомы, соматизацию, расстройства, связанные с изображением тела, и расстройство питания, представляют собой недооцененный, но клинически значимый аспект болезни. В настоящем докладе обобщаются данные, полученные от взрослого и педиатрического населения, с уделением особого внимания частому соучастию этих нарушений в рабо

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… ; self-esteem | BFI (neuroticism); RSES-10; BSQ-8; EAT-26; self-reported MS and SRDSS | Community-based MS sample recruited via online ads, support groups, and hospital noticeboards | 21% lifetime eating disorder; neuroticism linked to low self-esteem and body dissatisfaction; mediated eating disorder … Statistically significant correlations were observed between neuroticism, low self-esteem, body dissatisfaction, and eating disorder symptoms, suggesting a complex interplay among these psychological factors. …

Life Satisfaction and Its Relationship With Personality Traits Among Medical College Students in China.

BACKGROUND: Life satisfaction is a comprehensive psychological index to measure a person's life quality. Previous studies have found that po … mension was positively correlated with the life satisfaction score in each dimension except for the neuroticism dimension of personality (p<0.05). CONCLUSION: The life satisfaction of college students is different for different lifestyles. The student management department should pay attention to the physical and mental health of college students with low li …

Psychologic Factors Do Not Affect Placebo Responses After Upper Extremity Injections: A Randomized Trial.

BACKGROUND: Studies on how psychologic factors influence the placebo effect have shown conflicting results in an experimental setting. Pessimists are more likely to experience a nocebo effect (feel worse after an inert intervention), whereas other studies suggest that patients with more symptoms of depression or anxiety or greater neuroticism have a greater response to a placebo. This is important because treatment benefits are potentiated by placebo effects, and optimal utilization of this phenomenon may improve clinical outcomes. QUESTIONS/PURPOSES: (1) What psychologic factors are associat…

Risk. Impact of having a first-degree relative with affective disorder: a 7-year follow-up study.

This study investigated a high-risk sample in order to elucidate risk factors for affective disorder. Healthy monozygotic (MZ) and dizygotic … fy a cluster of prodromal symptoms encompassing subclinical anxiety and depressive symptoms, higher neuroticism and cognitive problems. The cognitive problems may further be related to the cross-sectional finding that high-risk twins had lower hippocampal volumes. Further, 2 genetic polymorphisms: the 5-HTTLPR and the brain-derived neurotrophic factor (BDNF) …

[Analgesic abuse and psychiatric comorbidity in headache patients].

Headache patients frequently overuse analgesic medications: 20% of the patients from headache centers is concerned by this problem, which ha … The presence of personality disorders in these patients is poorly documented, with the exception of neuroticism, which probably reflects the anxious and depressive comorbidity. Clinical findings show that a subgroup of patients needs an hospitalisation to succeed in withdrawal. They appears likely to be dependant on several types of drugs, to present with fea …

Idiopathic vulvodynia - a psychosomatic disease? A cross-sectional single-center study.

BACKGROUND: Idiopathic vulvodynia is a chronic vulvar pain condition that occurs with a high burden of disease and frustratingly low therape … s, nor to control women. A finding that was further emphasised by Wilcoxon rank-sum testing. Median neuroticism scores in idiopathic vulvodynia patients were, however, highest in patients that reported the least or medium symptom severity. CONCLUSIONS: Sexual violence/abuse rates of all vulvar pain groups were higher than the estimated rate in the general fem …

Real-World Meditation App Engagement: Longitudinal Study of the Medito Meditation App.

BACKGROUND: Meditation apps are increasingly popular but face significant engagement challenges. Most research does not meaningfully capture … s (ρ=0.091; P=.02), and conscientiousness (ρ=0.124; P=.003) were associated with higher engagement. Neuroticism was negatively associated with engagement (ρ=-0.103; P=.010). For mental health factors, satisfaction with life (ρ=0.123; P=.002) and well-being (ρ=0.135, P<.001) were associated with higher engagement, while perceived stress (ρ=-0.107; P=.007), psy …

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

IMPORTANCE: Alcohol dependence (AD) and major depression (MD) are leading causes of disability that often co-occur. Genetic epidemiologic da … rican participants. Analyses of polygenic risk scores showed that individuals with a higher risk of neuroticism (β = 1.01; 95% CI, 0.50-1.52) or depressive symptoms (β = 0.87; 95% CI, 0.32-1.42) and a lower level of subjective well-being (β = -0.94; 95% CI, -1.46 to -0.42) and educational attainment (β = -1.00, 95% CI, -1.57 to -0.44) had a higher level of AD …

Personality Traits Affect the Cost-Effectiveness of Total Knee Arthroplasty.

OBJECTIVE: To assess the clinical benefit and compare the cost-effectiveness of total knee arthroplasty (TKA) in patients with different per … in general, the extroversion (measured by the extroversion subscale) and stability (measured by the neuroticism subscale) displayed more pleasurable QALYs in comparison with introversion and instability (P < 0.05). Sensitivity analysis showed that the results mentioned above appeared not to be sensitive when varying key parameters (prosthesis survival and lif …

A chain mediation model reveals the association between metacognition and quality of life in hematologic tumor patients.

The study aims to explore the relationship among metacognition (MC), fear of disease of progression (FoP), psychological distress (PD), and quality of life (QoL), and verify whether FoP and PD have a chain mediating effect between MC and QoL. 231 hematologic tumor patients in a large tertiary hospital were investigated by using Meta-Cognitions Questionnaire-30, Fear of Progression Questionnaire-Short Form, Hospital Anxiety and Depression Scale, and Functional Assessment of Cancer Therapy scale. Data analyses were performed using IBM SPSS (version 25.0) and the PROCESS macro (version 4.1). The

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… Ng DWL Fear of cancer recurrence among Chinese cancer survivors: Prevalence and associations with metacognition and neuroticism Psycho Oncol. 2019 28 1243 1251 10.1002/pon.5073 30932279 Ng, D. W. L. et al. … Fear of cancer recurrence among Chinese cancer survivors: Prevalence and associations with metacognition and neuroticism. Psycho Oncol. 28 , 1243–1251. 10.1002/pon.5073 (2019). 10.1002/pon.5073 30932279 31. …

Пищевая зависимость от поведенческих пристрастий: сетевой подход.

СПРАВОЧНАЯ ИНФОРМАЦИЯ/AIMS: Сопоставимость психических расстройств является хорошо задокументированным явлением. Вместе с тем не было проведено никакого расследования по вопросу о соучастии и механизмах, лежащих в основе пищевой зависимости и поведенческих пристрастий. Таким образом, цели этого исследования заключались в следующем: a) проведение сетевого анализа для изучения взаимосвязей между клиническим профилем пациентов, нуждающихся в лечении от игорного расстройства, навязчивым расстройством, связанным с покупкой и покупкой (CBSD), навязанным расстройством сексуального поведения, и сопутс

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… Notably, high neuroticism and low levels of conscientiousness, extraversion, and openness are common across mood, anxiety, and psychotic disorders ( Marshall et al., 2012 ; Dupuis et al., 2016 ; Ohi et al., 2016 ). … For example, low conscientiousness, high neuroticism, and high narcissism have been associated as risk factors for the onset and progression of addictions ( Charzyńska et al., 2021 ). …

Нейропсихологические аспекты расстройств контроля импульсов в болезни Паркинсона.

Синдромы импульсного контроля (ИДД), такие, как чрезмерные азартные игры, навязчивое сексуальное поведение, поедание бингов, навязчивые покупки, а также синдром регулирования дофамина, могут возникать как изнурительное нервно-психическое осложнение болезни Паркинсона (PD). Хотя патофизиология не в полной мере понятна, она, вероятно, включает мезолимбичную допаминергическую чрезмерную оптимизацию в сочетании с факторами уязвимости, связанными с заболеваниями, в плане поощрения, мотивации и ингибиционных сетей контроля. В настоящем описательном обзоре резюмируются данные о нейропсихологических,

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… Neuroticism appears to be a particular risk factor, as higher levels of neuroticism increase the chance of ICD symptoms and medication addiction ( Callesen et al., 2014 ). … They reported elevated levels of neuroticism, perfectionism, introversion, and inflexibility related with obsessive-compulsive personality disorder ( Kapsomenakis et al., 2023 ). …

The impact of experiential avoidance on anxiety and depressive disorders in hematological cancer patients.

Anxiety disorders and/or depressive disorders co-occurring with hematological cancer are an additional burden for patients. Experiential avoidance (EA; efforts to avoid negative emotions, thoughts, or memories) is an empirically evident transdiagnostic factor for the onset and maintenance of anxiety and depressive disorders in non-cancer populations. There is lack of evidence on the impact of EA in predicting anxiety and depression in cancer patients. A total of 291 patients with hematological cancer (60% male, mean age 55 years) were included in this cross-sectional observational study. Parti

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… Personality variables such as neuroticism also contribute to a higher prevalence of comorbid mental disorders (Harrison & Maguire, 1994 ; Niedzwiedz et al., 2019 ). … In addition, some constructs of interest, such as psychosocial support, neuroticism, rumination, or intolerance of uncertainty, that might further explain experiences of EA in cancer patients were not assessed and future studies may investigate these constructs (Panjwani et al., 2024 ; Spinhoven et al …

Cumulative burden of psychiatric disorders and self-harm across 26 adult cancers.

Cancer is a life-altering event causing considerable psychological distress. However, information on the total burden of psychiatric disorders across all common adult cancers and therapy exposures has remained scarce. Here, we estimated the risk of self-harm after incident psychiatric disorder diagnosis in patients with cancer and the risk of unnatural deaths after self-harm in 459,542 individuals. Depression was the most common psychiatric disorder in patients with cancer. Patients who received chemotherapy, radiotherapy and surgery had the highest cumulative burden of psychiatric disorders.

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… Neuroticism is linked to poorer quality of life after cancer treatment in patients with breast cancer 39 . … Grov EK The personality trait of neuroticism is strongly associated with long-term morbidity in testicular cancer survivors Acta Oncol. (Madr.). 2009 48 842 849 10.1080/02841860902795232 19412812 41. Linsley KR Schapira K Kelly TP Open verdict v. suicide–importance to research Br. J. …

A Systematic Review of Trajectories of Clinically Relevant Distress Amongst Adults with Cancer: Course and Predictors.

To improve interventions for people with cancer who experience clinically relevant distress, it is important to understand how distress evolves over time and why. This review synthesizes the literature on trajectories of distress in adult patients with cancer. Databases were searched for longitudinal studies using a validated clinical tool to group patients into distress trajectories. Twelve studies were identified reporting trajectories of depression, anxiety, adjustment disorder or post-traumatic stress disorder. Heterogeneity between studies was high, including the timing of baseline assess

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… For instance, a recent systematic review concluded that the only consistent psychological predictors of clinically relevant distress longitudinally are initial distress and neuroticism (Cook et al., 2018 ). … Persistent or fluctuating trajectories (combined and compared to non-cases) were associated with younger age, more difficulties with daily activities, less social support than desired, lower optimism, and higher neuroticism. …