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Acceptance in Patients With Cancer: A Scoping Review.

BackgroundCancer is generally perceived as a major stressor. Occasionally, patients are able to accept their diagnosis and prognosis, and it is not uncommon for patients who initially experience great distress to eventually learn to accept their disease. A deeper understanding of acceptance can enable clinicians to better support patients in achieving a more peaceful state of mind. The purpose of this literature review was to provide a comprehensive overview of existing research on acceptance in patients with cancer.Recent findingsStudy selection resulted in the inclusion of 54 studies. All st

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… Feng | 2022 | The dyadic effects of personality traits on depression in advanced lung cancer patients and caregivers: The mediating role of acceptance of illness | China | This study aimed to explore the intrapersonal and interpersonal effects of three personality traits—neuroticism, extraversion and … Patients' and partners' neuroticism and extraversion were associated with their own acceptance of illness, which in turn were negatively associated with the depression of their counterpart (actor–partner effect). 44 | S. Wieder‐Huszla, J. Owsianowska, A. Chudecka‐Głaz, D. Branecka‐Woźniak, A. …

Psychosocial development of full term singletons, born after preimplantation genetic diagnosis (PGD) at preschool age and family functioning: a prospective case-controlled study and multi-informant approach.

STUDY QUESTION: Do full term singletons born after preimplantation genetic diagnosis (PGD) differ in their psychosocial functioning from chi … rents scored comparable with each other. PGD and ICSI mothers were emotionally more stable [NEO-FFi Neuroticism/emotionality: P = 0.013, η(2) = 0.066; 95% confidence interval (CI) 95% (0.003;0.148)]. They experienced less parental stress in general [PSI, Total stress: P = 0.001, η(2) = 0.102, 95% CI (0.02;0.192)] and on different sublevels opposed to their SC …

Resilience in Cancer Patients.

Background: Being diagnosed with cancer and undergoing its treatment are associated with substantial distress that can cause long-lasting negative psychological outcomes. Resilience is an individual's ability to maintain or restore relatively stable psychological and physical functioning when confronted with stressful life events and adversities. Posttraumatic growth (PTG) can be defined as positive life changes that result from major life crises or stressful events. Objectives: The aims of this study were to 1) investigate which factors can strengthen or weaken resilience and PTG in cancer pa

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… | Personality, cognitive/psychological traits and psychiatric resilience: a multivariate twin study | Retrospective study design | | SCL-90 Life Orientation Test Rosenberg Self-Esteem Scale | To determine the phenotypic relationships, and etiologic underpinnings, of cognitive/psychological traits (neuroticism … The association for all-cause mortality remained after adjustment for cigarette smoking history, social class, body mass index, systolic blood pressure, cholesterol, hostility, and neuroticism. …

Keyword Index for Volume 95

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… acetylcysteine 35 naevus 496 nasopharyngeal neoplasm 1269 NBCCS 548 NCI-60 panel 906 NDRG1 307 neoadjuvant 710 neoadjuvant chemoradiation 1174 neoadjuvant chemotherapy 1683 neoplasms 416, 1180, 1579 nephrectomy 1076 neuroblastoma 49, 879 neuroendocrine carcinoma 1148 neuroleptic medication 934 neuroticism …

Determinants and Clinical Significance of Musculoskeletal Symptoms in Patients With Chronic Graft-Versus-Host Disease.

Musculoskeletal symptoms in chronic graft-versus-host disease (cGVHD) are rare manifestations contributing to disease burden. This study assesses the frequency of muscle cramps, joint and muscle aches, and muscle weakness in a cohort of patients severely affected by cGVHD. Three hundred thirty-four patients participated in the NCI natural history study of cGVHD (NCT00092235) from October 2004 to March 2017. Five-point Lee cGVHD Symptom Scale was dichotomized (less symptom bother-0, 1, 2; severe symptom bother-3, 4) and tested for associations with: Short Form 36 (SF36), 2-minute walk test, gri

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… Fatigue symptoms in relation to neuroticism, anxiety-depression, and musculoskeletal pain. A longitudinal twin study. PLoS One. 2018;13:e0198594. 23. Kenzik K, Huang IC, Rizzo JD, et al. …

GWAS подчеркивает невральный вклад в подверженность множественным склерозам.

Множественный склероз (MS) — хроническое воспалительное и нейродегенеративное заболевание мозга и спинного мозга. Генетические исследования выявили множество рисковых лоси, которые, как считалось, в первую очередь влияют на иммунные клетки и микроглию. Здесь мы провели многокантрольное исследование генома связи с 20,831 МЗ и 729,220 контроль за участниками, выявление 236 Возможные варианты уязвимости за пределами основного комплекса four Роман-лочи. Мы вычислили полигенный балл для MS и, оптимизированный для европейского происхождения, он является информативным для афро-американских и латиноам

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… Interestingly, we also found significant positive correlations between MS and neuroticism (rg = 0.090, p-value = 2.00×10 −04 ). MS severity did not show any significant correlations with the traits we tested. … We have also downloaded four neurodegenerative diseases: Alzheimer’s disease (AD) 41 , Amyotrophic lateral sclerosis (ALS) 42 , Frontotemporal dementia (FTD) 43 , Parkinson’s disease (PD) 44 , four psychiatric disorders/traits: Bipolar disorder (BIP) 45 , Major depressive disorder (MDD) 46 , Neuroticism …

Исследование, посвященное детской травме и сексуальному нарциссизму у лиц с навязчивым сексуальным поведением, принимающих советы

Навязчивое сексуальное поведение (CSB) ассоциируется с травмами и безнадзорностью в детстве. Имеются свидетельства того, что ЦСБ имеет отношение к физическому и сексуальному насилию в отношении детей. Сексуальный нарциссизм был связан с агрессией, сексом в молодом возрасте и многими партнерами по сексу. В этом исследовании были рассмотрены связи между жестоким обращением с детьми и безнадзорностью, сексуальным нарциссизмом и гиперсексуальным поведением между участниками группы поддержки сексуальной зависимости и группой участников контроля. В нем приняли участие 118 взрослых, в том числе 72 му

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… Openness to experience and neuroticism positively correlated with sex addiction scores, whereas conscientiousness negatively correlated with sex addiction scores. …

Depression and anxiety among people living with and beyond cancer: a growing clinical and research priority.

BackgroundA cancer diagnosis can have a substantial impact on mental health and wellbeing. Depression and anxiety may hinder cancer treatment and recovery, as well as quality of life and survival. We argue that more research is needed to prevent and treat co-morbid depression and anxiety among people with cancer and that it requires greater clinical priority. For background and to support our argument, we synthesise existing systematic reviews relating to cancer and common mental disorders, focusing on depression and anxiety. We searched several electronic databases for relevant reviews on can

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… Personality factors, such as neuroticism, and existing coping skills may also contribute [ 11 ]. …

Haemato-oncology and burnout: an Italian survey.

This cross-sectional survey aimed to evaluate the prevalence of burnout and estimated psychiatric disorders among haemato-oncology healthcare professionals in Italy. The aspects of work that respondents perceive as stressful and satisfying have also been examined. The assessments were made using the Maslach Burnout Inventory (MBI), General Health Questionnaire and a study-specific questionnaire. Logistic regression models were applied to show associations between different sources of work-related stress and burnout. Three hundred and eighty-seven out of 440 (87.95%) returned their questionnair

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… Following individual factors have been found to be associated with burnout: being young, single and female, early life events, family or past history of psychiatric disorder, personality traits of neuroticism and self-criticism, lack of communication and management skills, surface learning style and …

Peri-transplant psychosocial factors and neutrophil recovery following hematopoietic stem cell transplantation.

ObjectiveMultiple psychosocial factors appear to affect cancer progression in various populations; however, research investigating the relationship between psychosocial factors and outcomes following hematopoietic stem cell transplantation (HCT) is scarce. Subject to adverse immunological and psychological conditions, HCT patients may be especially vulnerable to psychosomatic health sequelae; therefore, we studied whether optimism and anxiety influence the pertinent clinical outcome of days to neutrophil engraftment (DTE).Method54 adults undergoing either autologous or allogeneic HCT completed

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… Rev Clin Exp Hematol 5 : 67 – 86 . 11486655 10.1046/j.1468-0734.2001.00033.x 19 Scheier MF , Carver CS , Bridges MW ( 1994 ) Distinguishing optimism from neuroticism (and trait anxiety, self-mastery, and self-esteem): A reevaluation of the life orientation test . …

Time Goes Back-Time Perspective in Polish Men with Compulsive Sexual Behavior Disorder and Risky Sexual Behavior.

Many relationships between time perspective and a propensity to engage in risky behaviors or developing addictions have been demonstrated. The aim of our study was to determine the differences in intensity of individual time perspectives in people with compulsive sexual behavior disorder (CSBD) and risky sexual behavior (RSB). The analysis includes 425 men: 98 CSBD (age M = 37.99 years), 63 RSB (age M = 35.70 years), 264 without CSBD and RSB features constituting the control group (age M = 35.08 years). We used the Zimbardo Time Perspective Inventory, the Sexual Addiction Screening Test-Revise

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… For example, in a study of 233 individuals (age M = 21.4 years), past-negative TP increased the risk of FB use disorder, but only when it co-occurred with high levels of neuroticism [ 90 ]. …

The effect of exercise and nutrition interventions on physical functioning in patients undergoing haematopoietic stem cell transplantation: a systematic review and meta-analysis.

PurposeHaematopoietic stem cell transplantation (HSCT) is potentially lifesaving. However, it comes with negative consequences such as impaired physical functioning, fatigue and poor quality of life. The aim of this systematic review and meta-analysis is to determine the effect of exercise and nutrition interventions to counteract negative consequences of treatment and improve physical functioning in patients receiving HSCT.MethodsThis systematic review and meta-analysis included randomised controlled trials from three electronic databases between 2009 and 2020. The trials included adult patie

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… Chronic fatigue is highly prevalent in survivors of autologous stem cell transplantation and associated with IL-6, neuroticism, cardiorespiratory fitness, and obesity. Bone Marrow Transplant. 2019;54(4):607–610. doi: 10.1038/s41409-018-0342-y. 9. …

Use of methotrexate in adult-onset Still's disease.

We appreciate Lavigne-Robichaud et al`s critical remarks (1) to our systematic review addressing the epidemiological evidence for causal rel … s://doi.org/10.1111/j.2044-8325.1994.tb00545.x. 6. Shipley BA, Weiss A, Der G, Taylor MD, Deary IJ. Neuroticism, extraversion, and mortality in the UK Health and Lifestyle Survey: a 21-year prospective cohort study. Psychosom Med 2007 Dec;69(9):923-31. https://doi.org/10.1097/PSY.0b013e31815abf83. 7. Kasl SV. Measuring job stressors and studying the health im …

Home-based, telehealth, and hybrid exercise interventions for adults undergoing or recovering from hematopoietic stem cell transplantation: a systematic review of randomized controlled trials.

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is associated with substantial treatment-related morbidity, including reduced physical function, fatigue, and impaired quality of life. Home-based and telehealth-supported exercise may improve access to rehabilitation in this population, but randomized evidence remains limited. OBJECTIVE: To systematically review randomized controlled trials evaluating the effectiveness, feasibility, and safety of structured exercise interventions delivered in home-based, telehealth, or hybrid formats for adults undergoing or recovering from HSCT. ME

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… Smeland KB Loge JH Aass HCD Aspelin T Bersvendsen H Bolstad N Chronic fatigue is highly prevalent in survivors of autologous stem cell transplantation and associated with IL-6, neuroticism, cardiorespiratory fitness, and obesity . …

Potential drug targets for Neuromyelitis optica spectrum disorders (NMOSD): A Mendelian randomization analysis.

BackgroundCertain peripheral proteins are involved in the development of Neuromyelitis optica spectrum disorders (NMOSD), such as IL-6, complement proteins, and MHC class II molecules. However, the roles of other new protein biomarkers are unclear. Current NMOSD treatments (e.g., intravenous pulse methylprednisolone, or satralizumab for IL-6 receptor inhibition) can only manage symptoms, necessitating the identification of new drug targets to treat NMOSD. The objective of this study is to identify potential drug targets for NMOSD through Mendelian randomization (MR) analysis, thereby addressin

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… Assessing the Role of Cortisol in Anxiety, Major Depression, and Neuroticism: A Mendelian Randomization Study Using SERPINA6/SERPINA1 Variants . Biol Psychiatry Glob Open Sci . 2024 ; 4 ( 3 ):100294. …

Несоответствие между готовностью к вакцинации и фактическим состоянием вакцинации SARS-COV-2 у людей с множественным склерозом: продольное исследование.

Фон/цели: Заражение острым острым респираторным синдромом коронавируса типа 2 (SARS-COV-2) создает значительный риск для здоровья, особенно для лиц с хроническими заболеваниями. Множественный склероз (MS) является наиболее распространенным хроническим неврологическим расстройством с иммунной помощью, и вакцинация имеет важное значение для его лечения. Цель этого исследования заключалась в сопоставлении заявленной готовности к вакцинации против SARS-COV-2 с фактическим состоянием вакцинации людей с MS (PwMS) и выявлении факторов, объясняющих это несоответствие. Методы: В продольном двухцентрово

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… The five personality dimensions assessed were neuroticism, extraversion, openness, conscientiousness, and agreeableness. …

Managing fatigue in patients with primary Sjögren's syndrome: challenges and solutions.

Primary Sjögren's syndrome (pSS) patients identify fatigue as their most important symptom and the one most difficult to cope with, but there are still many challenges and few solutions to manage this debilitating symptom. Promising pharmacological treatments, such as rituximab, have failed in more stringent tests including randomized controlled trials (RCTs) and meta-analysis. While non-pharmacological interventions may be safer, less costly, and address other common comorbidities, to date only aerobic exercise seems to be effective at reducing fatigue in pSS. All interventions, pharmacologic

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… These include sleep disturbances, 21 – 23 autonomic dysfunction, 24 , 25 depression, 11 , 13 , 15 , 26 , 27 dysfunctional or alexithymic psychological profile, 28 neuroticism, and fibromyalgia. 15 These complex associations and comorbidities require appropriate management in clinical practice based on …

Тип общей генетической и нейроиммунной архитектуры 1 диабет с нейрокогнитивными признаками.

Тип 1 диабет, особенно в детстве, ассоциируется с изменяющимися нейрокогнитивными признаками, однако основные биологические механизмы неясны. Здесь мы интегрируем результаты общегеномной ассоциации с одноклеточных эпигеномических профилей и показываем этот тип 1 Наследственность диабета обогащается доступным хроматином клеток мозга человека, в первую очередь микроглией, через нейроразвитие до взрослого возраста. Анализ генетической корреляции, скорректированный по методу Bonferroni, показывает отрицательную корреляцию типа 1 диабет с интеллектом, исполнительными функциями и биполярным расстрой

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… Additional GWAS included cognitive traits (intelligence, educational attainment, EXF), psychiatric disorders (autism spectrum disorder, BPD, schizophrenia, obsessive-compulsive disorder, ADHD, major depression, PTSD, and neuroticism), neurological and neurodegenerative diseases (Alzheimer’s disease, …

Навязчивое сексуальное поведение может быть в большей степени похоже на состояние, чем на предательство: результаты трехлетнего продольного репрезентативного обследования.

ИСТОРИЯ ВОПРОСА О том, является ли принуждение к сексуальному поведению (CSB) устойчивым или переходным продольным курсом, является скудной и вызывает неоднозначные выводы, осложняющие его концептуализацию. Модель, включающая как специфические/стабильные факторы, так и факторы, характерные для конкретного состояния/окции, может уточнить направление и характер деятельности ЦСБ. Авторы преследовали цель определить долю различий в оценках ССБ, обусловленных специфическими/стабильными и государственными/окнесационными факторами, и проанализировать прочность авторегрессивного воздействия между посл

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… It can be assumed that an individual's temporally stable, habitual level of CSB may be shaped by factors such as stable personality characteristics (e.g., higher neuroticism, impulsivity, and difficulties in emotion regulation, lower agreeableness), early life experiences (e.g., insecure attachment patterns …

Многофакторный характер принятия репродуктивных решений женщинами с множественным склерозом.

ВВЕДЕНИЕ: Множественный склероз (МС) является хроническим неврологическим заболеванием, которое часто затрагивает женщин в их репродуктивном возрасте и может влиять на намерения в отношении фертильности и решения в области планирования семьи. Цель этого исследования заключалась в выявлении факторов, связанных с репродуктивным выбором женщин с НР, и в изучении роли психологических, социальных и связанных с болезнями переменных в процессе принятия решений о рождаемости. МЕТОДЫ: В период с августа в Греции было проведено перекрестное исследование. 2023 и декабрь 2024, включая 103 Женщины в возрас

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… The subscales also showed good internal consistency: extraversion (α=0.76), agreeableness (α=0.77), conscientiousness (α=0.78), neuroticism (α=0.79), and openness (α=0.71). …