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Adenoma Recurrence after Endoscopic Piecemeal Mucosal Resection of Colorectal Flat Lesions: Applicability of the Sydney EMR Recurrence Tool in a Non-Tertiary Centre.

INTRODUCTION: Endoscopic mucosal resection (EMR) is the treatment of choice for non-invasive colorectal flat lesions. When endoscopic piecem … were classified as SMSA (size, morphology, site, and access score) level 4. Adjunctive therapy with argon plasma coagulation (APC) was used in 37% (n = 67) of cases. The 6-month AR rate was 16% (n = 29). According to SERT groups, the AR rate was: SERT 0: 12% (14/120); SERT 1: 17% (6/35); SERT 2: 25% (3/12); SERT 3: 30% (3/10); SERT 4: 75% (3/4). Two of …

Interventions for dysphagia in oesophageal cancer.

BACKGROUND: Most patients with oesophageal and gastro-oesophageal carcinoma are diagnosed at an advanced stage and require palliative interv … dvantage and possibly a better quality of life, and might provide better results when combined with argon plasma coagulation or external beam radiation therapy. AUTHORS' CONCLUSIONS: Self-expanding metal stent insertion is safe, effective and quicker in palliating dysphagia compared to other modalities. However, high-dose intraluminal brachytherapy is …

Cold Atmospheric Plasma in the Treatment of Osteosarcoma.

Human osteosarcoma (OS) is the most common primary malignant bone tumor occurring most commonly in adolescents and young adults. Major improvements in disease-free survival have been achieved by implementing a combination therapy consisting of radical surgical resection of the tumor and systemic multi-agent chemotherapy. However, long-term survival remains poor, so novel targeted therapies to improve outcomes for patients with osteosarcoma remains an area of active research. This includes immunotherapy, photodynamic therapy, or treatment with nanoparticles. Cold atmospheric plasma (CAP), a hig

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… A noble gas, in this case argon, is driven into the head of the jet, where a high-frequency electrode ionizes argon molecules. … This argon plasma is then driven out into the vicinity where reactive argon molecules react with ambient-air resident oxygen and nitrogen molecules to form dozens of different reactive oxygen and nitrogen species. Major reactive moieties also dominate the coloring of the plasma effluent. …

Surgical findings and long-term hearing results in 3,050 stapedotomies for primary otosclerosis: a prospective study with the otology-neurotology database.

OBJECTIVE: To evaluate with a new otologic database the results of primary stapes surgery for otosclerosis with up to 14 years of follow-up … time after stapedotomy did not exceed the rate of hearing loss because of presbyacusis. Therefore, argon laser stapedotomy with vein graft interposition is our preferred surgical technique in the treatment of otosclerosis. Obliterative otosclerosis and simultaneous malleus ankylosis may be encountered during stapedotomy. Our study shows that reasonable …

New histone deacetylase inhibitors improve cisplatin antitumor properties against thoracic cancer cells.

Hemangiomas are common benign vascular tumors of infancy characterized by a proliferative growth phase followed by very slow inevitable regr … eated effectively by systematic drug therapy, sclerotherapy, laser therapy or combined therapy. The argon laser (514 nm in wavelength, 0.5 mm in depth) is useful in the treatment of superficial telangiectasias and small, flat cutaneous hemangiomas. Flashlamp-pumped pulsed-dye laser (FPDL, 585 nm or 595 nm in wavelength, 1.0-2.0 mm in depth) can be used …

[Own clinical experience in treatment of port-wine stain with KTP 532 nm laser].

UNLABELLED: Lesions of port-wine stain (PWS) type are the most commonly occurring vascular malformations of the skin which concerns about 0. … he continuation of other previously attempted treatment, which included excision and skin grafting, argon laser therapy, radiation therapy and pulsed dye laser treatment. The procedures were performed with at least 4-week intervals without, or under local and in children general anaesthesia. Therapeutic efficacy was evaluated independently by 3 surgeons …

Cold Atmospheric Pressure Plasma (CAP) as a New Tool for the Management of Vulva Cancer and Vulvar Premalignant Lesions in Gynaecological Oncology.

Vulvar cancer (VC) is a specific form of malignancy accounting for 5-6% of all gynaecologic malignancies. Although VC occurs most commonly in women after 60 years of age, disease incidence has risen progressively in premenopausal women in recent decades. VC demonstrates particular features requiring well-adapted therapeutic approaches to avoid potential treatment-related complications. Significant improvements in disease-free survival and overall survival rates for patients diagnosed with post-stage I disease have been achieved by implementing a combination therapy consisting of radical surgic

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… Several different gases can be used to produce cold atmospheric plasma, such as helium, argon, nitrogen, heliox, and air. Cold atmospheric plasma is created by many methods [ 170 ]. Each unique method can be used in different biomedical areas. … It is not CAP, however, but plasma argon beam coagulation that is used to treat, for example, multifocal VIN III lesions with a favourable clinical outcome. …

Risk Factors for Aspiration Pneumonia After Endoscopic Hemostasis.

BACKGROUND: Although all types of endoscopic procedures harbor risk of aspiration, little is understood about risk factors for aspiration pneumonia developing after endoscopic hemostasis. AIMS: The present study aimed to identify risk factors for aspiration pneumonia after endoscopic hemostasis. METHODS: Charts from consecutive patients with upper gastrointestinal bleeding that had been treated by endoscopic hemostasis at a single center between January 2004 and January 2015 were retrospectively reviewed. Patient information and clinical characteristics including cause of hemorrhage, establi

Exploring the applicability, combined strategies, and challenges of ablation in hematology based on its characteristics and immunomodulatory mechanisms.

Malignant hematological diseases, such as lymphoma, leukemia, and multiple myeloma, are frequently accompanied by clinical challenges including local progressive lesions, relapsed/refractory conditions, and poor tolerance to standard treatments in special populations. Systemic therapies represented by chemotherapy and targeted therapy have inherent limitations in addressing local tumor burden, relieving organ compression, and being suitable for frail patients. As a minimally invasive local treatment technology, ablation has been widely used in solid tumor therapy due to its advantages of preci

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… Cryoablation relies on argon and helium, which are relatively costly, limiting its popularization in resource-constrained areas. Moreover, the long-term efficacy of new carbon dioxide-based cryoablation devices requires confirmation through additional clinical data. … The Effect of Argon Gas Pressure on Ice Ball Size and Rate of Formation. Journal of Endourology, 2010, 24(Suppl 1): S59–S63. 10.1089/end.2009.0587 11. Nezami N, Khorshidi F, Mansur A, Habibollahi P, Camacho JC. …

Обобщение и оценка 6-ариламинобензамидов в качестве позитронных фотографических лигандов для рецептора фингозина-1-фосфата-5.

Спингосин-1-фосфат-5 (S1P5) является одним из пяти мембранных белковых рецепторов G, которые активируются лизофосфолипидом, фосфатом-1, что приводит к регулированию многих клеточных процессов. Рецепторы S1P5 расположены на олигодендроцитах и предлагаются для оказания влияния на физиологию олигодендроцитов. Понимание модуляции S1P5 в ходе таких процессов, как ремиелионация, может иметь потенциальные возможности для демиелионизации расстройств CNS, таких, как множественный склероз (MS). В этой связи мы сообщаем об обобщении и предварительной оценке серии фторированных 6-ариламинобензамидов в кач

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… Lithium chloride (0.0413 g, 0.975 mmol) was added and the mixture was degassed under argon, while stirring for 0.2 h. … Tetrakis(triphenylphosphine)palladium(0) (0.0451 g, 0.0390 mmol, 20 mol%) and hexamethylditin (0.0806 mL, 0.390 mmol) were added under argon and the reaction mixture was stirred under reflux for 21 h. …

[Analysis of influencing factors for bidirectional transformation between capillary dilatation and ulcerative types in chronic radiation rectal injury].

Objective: To investigate the differences in clinical characteristics between telangiectatic and ulcerative subtypes of chronic radiation re … 002], diseased bowel resection [3.8%(5/131) vs. 15.7%(31/198), χ2=11.34, P<0.001] and proportion of argon plasma coagulation (APC) treatment is lower [21.7%(43/198) vs. 36.6%(48/131), χ2=13.63, P=0.004]. The median follow-up time for the entire group of patients was 66 (4-186) months, During follow-up, subtype transformation occurred in 102 patients (31 …

Controlling Guest Diffusion by Local Dynamic Motion in Soft Porous Crystals to Separate Water Isotopologues and Similar Gases.

ConspectusThe precise and effective separation of similar mixtures is one of the fundamental issues and essential tasks in chemical research. In the field of gas/vapor separation, the size difference among the molecular pairs/isomers of light hydrocarbons and aromatic compounds is generally 0.3-0.5 Å, and the boiling-point difference is generally 6-15 K. These are necessary industrial raw materials and have great separation demands. Still, their separation mainly relies on energy-intensive distillation technology. On the other hand, remarkably similar substances such as oxygen/argon and isotop…

Sensing nitrogen limitation in Corynebacterium glutamicum: the role of glnK and glnD.

Psychosis only rarely occurs in patients with untreated Parkinson's disease. Much more commonly, psychosis is induced by drug therapy for Parkinson's disease and is the strongest known risk factor for nursing home placement. Delusions are less frequent than hallucinations, but are more concerning as they are often paranoid in nature. Treatment begins with a search for correctable infectious, toxic, and metabolic aetiologies. If symptoms persist, anti-Parkinson's disease medications are slowly reduced. However, withdrawal of these drugs usually worsens parkinsonism and is often not tolerated. C

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… Dry thoroughly with Argon/N 2 gas. Bake chips at 80 °C for 15 min. Store polymer-coated substrates/chips in a dry environment (vacuum desiccator) for up to 3 months until probe spotting procedure. 2. Preparation of Probe Array: Antibodies, antigens, ss/dsDNA, RNA, etc. … Depending on the type of experiment (wet vs. dry), dry the chip thoroughly with Argon gas and begin incubation or place the chip in a flow chamber and assemble. …

[The effect of sufentanil on cerebral blood flow, cerebral metabolism and the CO2 reactivity of the cerebral vessels in man].

Sufentanil, a synthetic opioid that is 5-10 times as potent as fentanyl, has been suggested for use during neurosurgical procedures because … d during hypocapnia (pa CO2 31.7 +/- 2 mmHg) (IV). Cerebral blood flow (CBF) was measured using the argon wash-in technique. Cerebral venous blood was obtained from a catheter in the superior bulb of the right internal jugular vein. Cerebral metabolic rates of oxygen (CMRO2) glucose (Mgluc) lactate (CMlac) were calculated by multiplying the arterial-cer …

L-662,583 is a topically effective ocular hypotensive carbonic anhydrase inhibitor in experimental animals.

1. L-662,583 was a potent inhibitor in vitro of purified, human erythrocyte carbonic anhydrase II, possessing an IC50 of 0.7 nM. The IC50 va … . 5. Unilateral ocular hypertension was elicited in the right eye of sedated, cynomolgus monkeys by argon laser-induced photocoagulation of the trabecular meshwork. The instillation (one drop of 50 microL) of L-662, 583 (2%) significantly lowered the elevated intraocular pressure of the right eye at all time points from 1 h up to and including 5 h. The …

Vertebral Primary Bone Lesions: Review of Management Options.

The assessment and treatment of vertebral primary bone lesions continue to pose a unique yet significant challenge. Indeed, there exists little in the literature in the way of compiling and overviewing the various types of vertebral lesions, which can often have complicated intervention strategies. Given the severe consequences of mismanaged vertebral bone tumors-including the extreme loss of motor function-it is clear that such an overview of spinal lesion care is needed. Thus, in the following paper, we aim to address the assessment of various vertebral primary bone lesions, outlining the re

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… Other types of adjuvant therapies, such as argon bean, hydrogen peroxide, liquid nitrogen, and alcohol, are being evaluated but have yet to demonstrate a significant impact [ 41 ]. … Additionally, laser technology such as the argon surgical laser is used as a micro-neurosurgical alternative approach. …

Translocation of inhaled ultrafine particles to the brain.

Ultrafine particles (UFP, particles <100 nm) are ubiquitous in ambient urban and indoor air from multiple sources and may contribute to adve … )C particles (CMD = 36 nm; GSD = 1.66) from [(13)C] graphite rods by electric spark discharge in an argon atmosphere at a concentration of 160 microg/m(3). Rats were exposed for 6 h, and lungs, cerebrum, cerebellum and olfactory bulbs were removed 1, 3, 5, and 7 days after exposure. (13)C concentrations were determined by isotope ratio mass spectroscopy …

Recurrent Respiratory Papillomatosis (RRP)-Juvenile Onset.

In this article, we describe the treatment of long standing juvenile-onset recurrent respiratory papillomatosis (JORRP) with eventual transformation to carcinoma in a patient who lived to the age of 73. Treatment modalities consisted of bronchoscopy and local excision initially. Later, YAG and CO2 laser debulking were used. Radiotherapy, chemotherapy with carboplatin (300 mg/m2) and 5-FU (600 mg/m2), oral methotrexate (5-7.5 mg/week), pegylated Interferon, indole-3-carbamide, and intralesional cidofovir were also utilized in the treatment of this patient. Except for methotrexate, each of the t

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… In July 2004 for stomal obstruction secondary to recurrent/worsening laryngeal tracheobronchial papillomatosis, an Argon laser coagulation (60minutes) was performed and the debulking of the tumor allowed mild relief of her symptoms. … These tissue regions are then exposed to a certain wavelength via an argon laser. …

AGA Clinical Practice Update on the Use of Electrosurgery in Therapeutic Endoscopy: Expert Review.

DESCRIPTION: This American Gastroenterological Association (AGA) Institute Clinical Practice Update aims to review the available evidence an … non-lifting fibrosis. BEST PRACTICE ADVICE 11: The endoscopist should understand the principles of argon plasma coagulation as a non-contact method of delivering electrosurgical energy and how gas flow and power parameters can be adjusted to achieve the desired tissue effect. BEST PRACTICE ADVICE 12: Endoscopists should understand how to optimally deli …

Septotomy and Balloon Dilation to Treat Chronic Leak After Sleeve Gastrectomy: Technical Principles.

BACKGROUND: Chronic leaks after laparoscopic sleeve gastrectomy (LSG) are often difficult to treat by endoscopy metallic stent. Septotomy ha … to "reshape" this area by septotomy. Septotomy procedure: Sequential incisions were performed using argon plasma coagulation (APC) with 2.5 flow and 50 W (WEM, SP, Brazil) over the septum in order to allow communication between the perigastric cavity (leak site) and the gastric lumen. The principles below must be followed: (1) Scope position: the endosc …