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Cytotoxic, antioxidant and antimicrobial activities and phenolic contents of eleven salvia species from iran.

The plants of the genus Salvia synthesize several types of secondary metabolites with antimicrobial, cytotoxic, and radical scavenging activities and are used in the folk medicine of different countries. Eleven Salvia species including S. aegyptiaca, S. aethiopis, S. atropatana, S. eremophila, S. hypoleuca, S. limbata, S. nemorosa, S. santolinifolia, S. sclarea, S. syriaca, and S. xanthocheila were collected from different localities in Iran and screened for their cytotoxic activity using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) colorimetric assay. The antioxidant pot…

Torque teno mini virus infection in chronic cervicitis and cervical tumors in Isfahan, Iran.

OBJECTIVES: Torque teno mini virus (TTMV) is classified as the Betatorquevirus genus of Anelloviridae. Little is known about the prevalence … is cases and 42 tumors were collected from histopathological files of Al-Zahra Hospital in Isfahan, Iran. DNA was extracted and subjected to nested polymerase chain reaction. RESULTS: Totally 62% of the tested samples were positive for TTMV. It was positive in 52.4% of adenocarcinoma, 68.4% of CIN and 100% SCC cases. In cervicitis, 48% of the cases we …

First Report of Pharyngostomy Wound Myiasis Caused by Chrysomya bezziana (Diptera: Calliphoridae) in Iran.

Wound or traumatic Myiasis is the infestation of animal and human orifices or wounds by dipterous larvae. It is more common in tropical and sub-tropical countries. Chrysomya bezziana is a major agent of wound myiasis throughout the tropical regions of the Old World. In Iran many cases of human myiasis due to C. bezziana were reported from south and south-east of country. This study reports a case of wound myiasis in a 3-year-old pharyngostomized girl who referred to the Pediatric Hospital in Bandar Abbas for pharyngological follow-up. During the examination, several live and mobile larvae were…

Canine visceral leishmaniasis in boyer ahmad district, kohgiluyeh & boyer ahmad province, southwest of iran.

BACKGROUND: Mediterranean type of visceral leishmaniasis (VL) is present in different parts of Iran. Several studies have identified dogs as the main reservoirs of the VL caused by Leishmania infantum in Iran and other Mediterranean regions. This study aimed to determine the seroprevalence of canine visceral leishmaniasis as animal reservoir host for human visceral leishmaniasis in Boyer Ahmad district in southwest of Iran. METHODS: A seroepidemiological study was carried out to determine the seroprevalence of canine visceral leishmaniasis (CVL) among ownership dogs by using direct agglutinat…

Explosive attack: Lessons learned in Seyed Al Shohada mosque attack, April 2008, Shiraz, Iran.

INTRODUCTION: The threat of explosive attacks has become a worldwide problem. Bombing is the preferred method of attacks. These attacks result in specific physical and psychiatric trauma. In this paper, we present an epidemiologic description of the physical injuries of patients who survived the explosive attack in Seyed Al Shohada mosque April 2008 Shiraz, Iran. MATERIALS AND METHODS: All medical records of the patients admitted at Shiraz Hospitals on April 2008 due to Seyed Al Shohada mosque bombing attacks, Shiraz, Iran, were reviewed. RESULTS: A total of 202 patients were referred to the…

Молекулярное обнаружение вируса геморрагической лихорадки Крымско-Конго (CFV) в клещах из юго-восточного Ирана.

Крымско-конголезский вирус геморрагической лихорадки (CFV) является членом рода Найровирус, семейства Буньявирида. Вирус CFV был изолирован от по крайней мере 31 вида клещей. Вирус передается через укус зараженного клеща или путем прямого контакта с инфицированными вирусом пациентами CFV или с продуктами инфицированного скота. Это исследование было проведено с целью определения степени распространения вируса CFV в клещах в районе Захедан в провинции Систан и Белуджистан на юго-востоке Ирана. В Систане и Белуджистане было собрано в общей сложности 140 клещей. Обратная транскрипция политимеразы

Совпадение в аннотации оригинала
Crimean-Congo haemorrhagic fever (CCHF) virus is a tick-borne member of the genus Nairovirus, family Bunyaviridae. CCHF virus has been isola … ection in ticks in the district of Zahedan, in the province of Sistan and Baluchistan, southeastern Iran. A total of 140 ticks were collected from Sistan and Baluchistan. Reverse transcriptase-polymerase chain reaction (RT-PCR) was used for the detection of the CCHF virus genome in the tick population. This genome was detected in 4.3% of ticks collecte …

Four cases of brown-vialetto-van laere syndrome from Iran: Clinical and electrophysiologic findings.

Brown-Vialetto-Van Laere syndrome (BVVLS) is a rare neurological disorder. We report our finding about four patients clinically and electrophysiologically diagnosed as BVVLS and denoted their clinical features with comparison to previous reports. The first symptom was bilateral hearing loss and the onset of other cranial nerves involvement varied between 0-15 years. Our patients represented some rare features like upper motor neuron signs in one patient and two cases interestingly developed some clinical improvement. This is the first report of BVVLS from Iran. Our patients which represent Cau…

Low-altitude outbreaks of human fascioliasis related with summer rainfall in Gilan province, Iran.

Following human fascioliasis outbreaks in 1988 and 1999 in Gilan province, northern Iran, efforts are now made to shed light on the seasonal pattern of fascioliasis transmission in this endemic area, taking into account snail host populations, climatic conditions and human cases. Populations of the intermediate host snail (Lymnaea spp.) peak in May and November, while there is a fourfold increase in the rate of human fascioliasis in February compared to that of September. Transmission is likely to occur mainly in late autumn and sporadically in late spring. Rainfall, seasonally analysed in per…

Multivariate disease mapping of seven prevalent cancers in Iran using a shared component model.

BACKGROUND: The aim of this study was to model the geographical variation in incidence and risk factors of seven prevalent cancers in Iran. METHODS: The data for cancers of esophagus, stomach, bladder, colorectal, lung, prostate, and female breast along with their risk factors in all 30 provinces of Iran for the year 2007 were included into study. Smoking, overweight, inadequate consumption of fruits and vegetables, socioeconomic status and low physical activity were studied as risk factors. Standardized incidence ratios were estimated using full bayesian model. In addition, the shared compon…

Blood culture contamination in a neonatal intensive care unit in Shiraz, Southwest-Central Iran.

OBJECTIVE: To measure bacterial contamination rates in blood culture specimens and distinguish sepsis from blood culture contamination in newborn hospitalized patients in a neonatal intensive care unit and to recognize the most commonly isolated bacteria. MATERIALS AND METHODS: Blood samples of 578 neonates were collected and cultured throughout the year of study (March 2006 to February 2007). Isolated bacteria were identified by traditional biochemical tests. Clinical criteria combined with laboratory data were used to differentiate the contaminated cultures from clinically significant cultu

Prevalence of aggressive periodontitis in 15-18 year old school-children in Tehran, Iran.

OBJECTIVE: Aggressive periodontitis is one of the periodontal diseases that affects systemically healthy individuals usually under the age of 30 years. The disease is characterized by rapid bone destruction which is inconsistent with the amount of bacterial plaque. The purpose of this cross-sectional study is to determine the prevalence of aggressive periodontitis among students aged 15 to 18 years in high schools of Tehran, Iran. RESEARCH DESIGN: Based on systematic and cluster random sampling, 5,590 students were selected. Probing pocket depth on six areas of incisors and first molars was c…

Seroepidemiological study of visceral leishmaniasis in Booyerahmad district, south-west Islamic Republic of Iran.

Visceral leishmaniasis (VL) is endemic in parts of Islamic Republic of Iran. A cross-sectional seroprevalence study was carried out in children in Booyerahmad district in the south-west of the country. Serum samples were taken from 1628 children up to 10 years old from different areas in Booyerahmad in 2005-06. AntiLeishmania antibody was detected in 50 out of 1628 children (3.1%) by direct agglutination test (antibody titre > or = 1:3200). There was no significant difference in seropositivity between the sexes (2.8% males and 3.3% females). The highest rate of infection (5.2%) was in the age …

Sand fly Surveillance within an Emerging Epidemic Focus of Cutaneous Leishmaniasis in Southeastern Iran.

BACKGROUND: Cutaneous leishmaniasis due to Leishmania major has become a hot topic in Iran. The objective of this study was to determine some ecological aspects of sand flies in the study area. METHODS: Sand flies were collected biweekly from indoors and outdoors fixed places in the selected villages, using 30 sticky paper traps from the beginning to the end of the active season of 2006 in Kerman Province, south of Iran. The flies were mounted and identified. Some blood fed and gravid female sand flies of rodent burrows and indoors were dissected and examined microscopically for natural proma…

Strongyloides stercoralis: The Most Prevalent Parasitic Cause of Eosinophilia in Gilan Province, Northern Iran.

BACKGROUND: Eosinophilia occurs in a wide variety of situations such as parasitic infections, allergic disorders, and malignancies. Most cases of eosinophilia of parasitic origin, especially those with a tissue migration life cycles consists of human infections by helminth parasites. The aim of present study was to determine the parasitic causes of eosinophilia in patients in a major endemic area of human fascioliasis in Gilan Province, northern part of Iran. METHODS: One hundred and fifty patients presenting with an elevated eosinophilia attending infectious disease clinics with or without c…

First Report of Human Nasal Myiasis Caused by Eristalis tenax in Iran (Diptera: Syrphidae).

We report a case of human nasal myiasis caused by flower fly larva in a 14-year-old rural girl in Central Province of Iran. Entomological studies on larva showed the larva as Eristalis tenax which is a rarely cause of nasal myiasis. This is the first reported case of E. tenax larva causing human nasal myiasis in Iran.

Lack of association between paraoxonase-1 Q192R polymorphism and rheumatoid arthritis in southeast Iran.

Decreased paraoxonase-1 (PON1) activity has been associated with rheumatoid arthritis. There are two polymorphisms in serum PON1; one differ … 2R polymorphism was not found to be correlated with increased risk for rheumatoid arthritis in this Iranian population.

Attitude toward prenatal diagnosis for beta-thalassemia major and medical abortion in Southern Iran.

The aim of this study was to evaluate the degree of acceptability of prenatal diagnosis and voluntary termination of pregnancy in case of a fetus affected with beta-thalassemia major (beta-TM) in patients and their parents in Southern Iran. We interviewed 510 parents who had beta-TM children and 254 patients. A questionnaire was used to record information regarding sex, age, parents' and patients' knowledge about prenatal diagnosis, and their decision regarding abortion of an affected fetus. Of 764 participants, 565 (73.9%) knew a little about prenatal diagnosis and 198 (25.9%) had no knowledg…

Frequency of myasthenia gravis in multiple sclerosis: Report of five cases from Isfahan, Iran.

This study was designed to determine the frequency and clinical characteristics of myasthenia gravis (MG) in a large cohort of Persian patients with multiple sclerosis (MS) living in the province of Isfahan. We reviewed the case records of patients with definite MS (McDonald's criteria) registered in the Isfahan MS Society (IMSS) for associated MG. Of the 1,718 patients with MS in the registry, six patients were found to have both MS and MG. The prevalence after excluding one patient with insufficient data, was 291 per 100,000 (0.29%), a higher prevalence than the earlier reports. These result

Immune response to measles vaccine after mass vaccination in Urmia, Islamic Republic of Iran.

We investigated the effectiveness of the mass measles vaccination campaign in Urmia, Islamic Republic of Iran, by examining the measles IgG seroprevalence and antibody response from paired data before and after the campaign. The overall seropositive rate of 624 subjects aged 5-25 years increased 1 year after the mass vaccination (from 53.0% to 72.3%). A rise in antibody titre occurred in all age groups except the 21-25 years group, which had the highest titre before mass vaccination. On logistic regression analysis, only immune status prior to vaccination was significantly associated with the …

Extensively drug-resistant tuberculosis treatment outcome in Iran: a case series of seven patients.

BACKGROUND: Extensively drug-resistant tuberculosis (XDR-TB) has recently been identified as a major threat to global health. XDR-TB poses a risk of higher failure rates and death during TB treatment. We report herein the outcomes of XDR-TB in patients treated with the standardized regimen in Iran. PATIENTS AND METHODS: Between 2002 and 2006, seven patients were diagnosed with XDR-TB. All patients were treated with the standardized second-line regimen containing cycloserine, prothionamide, amikacin, and ofloxacin. First-line drugs, such as ethambutol and pyrazinamide, were added to the regime…