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Survival outcomes and quality of life after percutaneous cryoablation for liver metastasis: A systematic review and meta-analysis.

BackgroundLiver metastasis is present in a wide range of malignancies, with colorectal cancer as the most common site. Several minimally invasive treatments have been suggested for managing hepatic metastases, and cryoablation is among them, yet not widely used. In this systematic review, we aimed to assess the effectiveness of percutaneous cryoablation in all types of liver metastases.MethodsA systematic search was performed in international databases, including PubMed, Scopus, Embase, and Web of Science, to find relevant studies reporting outcomes for percutaneous cryoablation in liver metas

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… The current method of cryoablation is the administration of probes with the use of circulating cooled fluid or gas, such as nitrogen or argon, which then expands into a gas, creating low temperatures, including the Joule-Thomson effect [ 12 ]. … Another challenge in LMICs might be the availability of argon gas as one of the main gases used in the cryoablation procedure. Hence, all these should be considered in the evaluation of the possible use of cryoablation. …

Доклад по делу и всеобъемлющий обзор литературы: редкий случай экстрамуллярной плазмоцитомы в трахее.

Этот случай описывает редкий случай изолированной экстрамуллярной плазмоцитомы в трахее 69-year-old Женщины, страдающие острыми респираторными расстройствами 1 h До поступления. Вычисленная томография грудной клетки (CT) выявила нокулярное повреждение внутри трахеи, которое характеризовалось маргинальной кальцинацией и сильным стратозом трахеиального люмена. Фибероптическая бронхоскопия показала, что носовое повреждение значительно помешало люмену дыхательных путей. Пациент прошел технически требовательную процедуру детонации эндоскопической опухоли. Гистопатологический анализ с помощью эндоск

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… Urgent endoscopic tumor ablation was performed using techniques such as electrocautery snaring, electrocautery resection, argon plasma coagulation, and laser ablation of calcified lesions to remove the affected tissue. Two endoscopic tumor debulking procedures were conducted at one-week intervals. …

Laser photocoagulation for proliferative diabetic retinopathy.

BACKGROUND: Diabetic retinopathy is a complication of diabetes in which high blood sugar levels damage the blood vessels in the retina. Some … with non-proliferative retinopathy. Four of the studies evaluated panretinal photocoagulation with argon laser and one study investigated selective photocoagulation of non-perfusion areas. Three studies compared laser treatment to no treatment and two studies compared laser treatment to deferred laser treatment. All studies were at risk of performance …

Treatment of bone tumours by radiofrequency thermal ablation.

Radiofrequency thermal ablation (RFTA) is considered the treatment of choice for osteoid osteomas, in which it has long been safely used. Other benign conditions (chondroblastoma, osteoblastoma, giant cell tumour, etc.) can also be treated by this technique, which is less invasive than traditional surgical procedures. RFTA ablation is also an option for the palliation of localized, painful osteolytic metastatic and myeloma lesions. The reduction in pain improves the quality of life of patients with cancer, who often have multiple morbidities and a limited life expectancy. In some cases, these

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… Use of an adjuvant therapy such as phenol, liquid nitrogen or argon beam coagulator may help to reduce the risk of local recurrence. The created defect should be carefully filled with impacted, antibiotic-laden, morcellized graft bone from the bone bank [ 28 , 29 ]. …

Predictive Value of the Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Monocyte-to-Lymphocyte Ratio Esophageal Stricture After Endoscopic Submucosal Dissection of Early Esophageal Cancer.

BACKGROUND Endoscopic submucosal dissection (ESD) has become a preferred treatment method for patients with early esophageal cancer (EEC), but it can easily be complicated by esophageal stricture. In this study, we aimed to analyze the predictive value of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR) for post-ESD esophageal stricture of EEC. MATERIAL AND METHODS A retrospective study of 285 patients with EEC who underwent ESD was conducted. Patients were divided into 2 groups according to whether there were complications of eso

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… Argon gas is marked 5 mm outside the lesion, and the electric knife is used to mark the tumor margin outside the mark. …

Case Report: Management of Primary Tracheobronchial Light Chain Amyloidosis in a Patient With Biclonal Gammopathy Using a Systemic Bortezomib-Based Regimen.

Primary tracheobronchial light chain (AL) amyloidosis is a rare and heterogeneous disease characterized by the buildup of amyloid deposits in the airway mucosa. Although its treatment remains challenging, the current view is that the localized form can be treated conservatively due to its slow progression. While radiotherapy has proven effective in treating localized form of the disease, some patients do not respond to local treatment and continue to experience poor quality of life, highlighting the need to explore additional treatment strategies. In this report, we discuss a case of primary t

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… The patient underwent rigid bronchoscopy with argon plasma coagulation (APC) and Nd:YAG laser debridement for the treatment of his endobronchial obstruction. However, this did not improve the patient's dyspnea with massive expectoration. …

AGA Clinical Practice Update on Management of Ampullary Neoplasms: Expert Review.

DESCRIPTION: Although ampullary neoplasia is a rare entity and represents 0.6%-0.8% of gastrointestinal cancers, the incidence among young a … tandard hemostasis techniques, such as epinephrine injection, electrocoagulation, use of hemoclips, argon plasma coagulation, and hemostatic sprays, may all be carefully employed for treating bleeding from endoscopic papillectomy. BEST PRACTICE ADVICE 12: Following endoscopic papillectomy, surveillance should begin at 3 months, with side-viewing duodeno …

[Nonarteritic ischemic optic neuropathy animal model and its treatment applications].

Nonarteritic ischemic optic neuropathy (NAION) is one of the most common acute unilaterally onset optic nerve diseases. One management probl … tail vein of SD rats, the small vessels of the left optic nerve were photoactivated using a 514 nm argon green laser (RB-laser-induction). In the RB-laser-induction eyes, the capillaries within the optic disc were reduced markedly, the optic disc became swollen, and fluorescein angiography showed filling defect in the choroid and the optic disc at an e …

Минимально инвазивное плазменное устройство для борьбы с множественным раком кожи Бенигена, связанное с сериями Rare Gendermatoses-Cases, и обзор терапевтических методов.

Фон: Немеланоцитические доброкачественные опухоли кожи включают в себя разнообразную группу повреждений, классифицированных по признаку их клеточного происхождения, таких, как эпидермальные, сосудистые, волокнистые, нейронные, мышечные и аднексальные опухоли. Хотя они часто обнаруживают повреждения в одиночестве, многочисленные опухоли кожи сосредотачиваются на генодерматозах. Каждый синдром обладает различными клиническими характеристиками и потенциальными осложнениями, включая категорические и внекачественные недуги, некоторые из которых могут представлять опасность для жизни. Диагнозные ген

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… Treatment of sebaceous adenoma with Argon, CO 2 , or KTP lasers are published as case reports out of the scope of MTS [ 116 , 117 , 118 , 119 , 120 ]. … Adenoma sebaceum: Successful treatment with the argon laser Plast. Reconstr. Surg. 1982 70 91 93 10.1097/00006534-198207000-00021 7089113 118. Wheeland R.G. Bailin P.L. Kantor G.R. Walker N.P. Ratz J.L. Treatment of adenoma sebaceum with carbon dioxide laser vaporization J. Dermatol. Surg. …

Proteasome inhibition protects blood-brain barrier P-glycoprotein and lowers Aβ brain levels in an Alzheimer's disease model.

BackgroundLoss of P-glycoprotein (P-gp) at the blood-brain barrier contributes to amyloid-β (Aβ) brain accumulation in Alzheimer's disease (AD). Using transgenic human amyloid precursor protein (hAPP)-overexpressing mice (Tg2576), we previously showed that Aβ triggers P-gp loss by activating the ubiquitin-proteasome pathway, which leads to P-gp degradation. Furthermore, we showed that inhibiting the ubiquitin-activating enzyme (E1) prevents P-gp loss and lowers Aβ accumulation in the brain of hAPP mice. Based on these data, we hypothesized that repurposing the FDA-approved proteasome inhibitor

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… Per treatment group, images of 7–15 capillaries were acquired using a Zeiss LSM 710 inverted confocal microscope (40 × 1.2 NA water immersion objective, 488 nm line of argon laser, Carl Zeiss Inc., Thornwood, NY, USA). Isolated capillaries adhering to the glass cover slip were randomly selected. … Immunofluorescence was visualized using a Zeiss LSM 710 inverted confocal microscope (40 × 1.2 NA water immersion objective, 488 nm line of argon laser, Carl Zeiss Inc., Thornwood, NY, USA). Per treatment group, confocal images of 10 capillaries were acquired. …

Pericytes as targets in hereditary hemorrhagic telangiectasia.

Defective paracrine Transforming Growth Factor-β (TGF-β) signaling between endothelial cells and the neighboring mural cells have been thought to lead to the development of vascular lesions that are characteristic of Hereditary Hemorrhagic Telangiectasia (HHT). This review highlights recent progress in our understanding of TGF-β signaling in mural cell recruitment and vessel stabilization and how perturbed TGF-β signaling might contribute to defective endothelial-mural cell interaction affecting vessel functionalities. Our recent findings have provided exciting insights into the role of thalid

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… Surgical replacement of nasal epithelium by skin, argon laser coagulation or antioxidants is also used and shows efficacy (Sadick et al., 2003 ; Lesnik et al., 2007 ; de Gussem et al., 2009 ). … [Argon plasma coagulation and topically applied estriol. Long-term results in the treatment of hereditary hemorrhagic telangiectasia of the nasal mucosa] . HNO 51 , 118 – 124 . 10.1007/s00106-002-0666-0 12589417 Sagare A. P. Bell R. D. Zhao Z. Ma Q. Winkler E. A. Ramanathan A. . ( 2013 ). …

Predicting survival in cancer patients: the role of cachexia and hormonal, nutritional and inflammatory markers.

BACKGROUND: Cancer can lead to weight loss, anorexia, and poor nutritional status, which are associated with decreased survival in cancer patients. METHODS: Male cancer patients (n = 136) were followed for a mean time of 4.5 years. Variables were obtained at baseline: cancer stage, albumin, hemoglobin, tumor necrosis factor alpha (TNF-α), interleukin (IL)-6, bioavailable testosterone, appetite questionnaire, and weight change from baseline to 18 months. Primary statistical tests included Kaplan-Meier survival analysis and Cox proportional hazard regression (PHREG). RESULTS: Univariate PHREG

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… Tas F, Duranyildiz D, Argon A, Oguz H, Camlica H, Yasasever V, et al. Serum levels of leptin and proinflammatory cytokines in advanced-stage non-small cell lung cancer. Med Oncol. 2005;22:353–8. doi: 10.1385/MO:22:4:353. 29. Dulger H, Alici S, Sekeroglu MR, Erkog R, Ozbek H, Noyan T, et al. …

Non-surgical interventions for late rectal problems (proctopathy) of radiotherapy in people who have received radiotherapy to the pelvis.

BACKGROUND: This is an update of a Cochrane review first published in 2002, and previously updated in 2007. Late radiation rectal problems ( … high risk of bias. The only treatments that made a significant difference on primary outcomes were argon plasma coagulation (APC) followed by oral sucralfate versus APC with placebo (endoscopic score 6 to 9 in favour of APC with placebo, risk ratio (RR) 2.26, 95% confidence interval (CI) 1.12 to 4.55; 1 study, 122 participants, low- to moderate-quality …

Обзор заболеваний, связанных с палидомидом и пищеварительной системой.

Талидомид, когда-то обнаруженный и используемый для лечения беременной болезни, вышел из фаворита с скандалами тератогенности, а затем вновь вошёл в общественный глаз с его удивительной эффективностью против проказы и множественной миеломы, и его антиопухоль и антивоспалительные эффекты были постепенно обнаружены. В последние годы талидомид также стал играть все более важную роль в расстройствах пищеварения, особенно в связи с его антиангиогенными последствиями, которые являются эффективными при лечении диспластического желудочно-кишечного кровоизлияния. В ряде клинических испытаний и отчетов

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… In addition recurrent bleeding from the watermelon stomach associated with cirrhosis cannot be controlled by argon knife coagulation therapy (APC), but can be successfully treated with thalidomide ( 24 ). …

Calcium Phosphate Ceramics Can Prevent Bisphosphonate-Related Osteonecrosis of the Jaw.

Bisphosphonate-associated osteonecrosis of the jaw (BRONJ), a post-surgical non-healing wound condition, is one of the most common side effects in patients treated with nitrogen-containing bisphosphonates. Its physiopathology has been related with suppression of bone turnover, of soft tissue healing and infection. Biphasic calcium phosphates (BCP) are used as a drug delivery vehicle and as a bone substitute in surgical wounds. Due to their capacity to adsorb zoledronate, it was hypothesized these compounds might have a protective effect on the soft tissues in BRONJ wounds. To address this hypo

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… For this, ultra-pure water was used, and the final solution was degassed with argon. For labeling, sodium pertechnetate activity (130–160 MBq) was added. …

Interventions for central serous chorioretinopathy: a network meta-analysis.

BACKGROUND: Central serous chorioretinopathy (CSC) is characterized by serous detachment of the neural retina with dysfunction of the choroi … nti-VEGF (ranibizumab, bevacizumab), PDT (full-dose, half-dose, 30%, low-fluence), laser treatment (argon, krypton and micropulse laser), beta-blockers, carbonic anhydrase inhibitors, Helicobactor pylori treatment, and nutritional supplements (Icaps, lutein); there were only one or two trials contributing data for each comparison. We downgraded for risk …

Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines.

The availability of metamizole varies greatly around the world. There are countries such as the USA, UK, or Australia where the use of metamizole is completely forbidden, and there are also countries where this drug is available only on prescription (e.g., Greece, Italy, Spain, etc.) and those in which it is sold OTC-over the counter (e.g., most Asian and South American countries). Metamizole, as a drug with a strong analgesic effect, is used as an alternative to other non-steroidal anti-inflammatory drugs, alone or in combination with opioid drugs. Risedronate sodium is a third-generation bis

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… The samples were analysed using a flow cytometer (FACSCalibur, Becton Dickinson, Franklin Lakes, NJ, USA) equipped with an argon laser with an excitation wavelength of 488 nm. The mean with the standard deviation of four independent repetitions was given as the final result. 2.6. …

Impact of preoperative anemia on outcomes in patients undergoing curative resection for gastric cancer: a single-institution retrospective analysis of 2163 Chinese patients.

We sought to evaluate whether preoperative anemia was an important determinant of survival in gastric cancer (GC). A single institution cohort of 2163 GC patients who underwent curative resection were retrospectively analyzed. Anemia was defined as a preoperative hemoglobin level <120 g/L in males and <110 g/L in females. Overall survival (OS) was analyzed using the Kaplan-Meier method, and a multivariate Cox proportional hazards model was performed to identify the independent prognostic factor. Anemic patients had a poorer OS compared with nonanemic patients after resection for tumor-nodes-me

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… Tas, F. , Eralp Y., Basaran M., Sakar B., Alici S., Argon A., et al. 2002. Anemia in oncology practice: relation to diseases and their therapies. Am. J. Clin. Oncol. 25:371–379. 3. Mercadante, S. , Gebbia V., Marrazzo A., and Filosto S.. 2000. Anaemia in cancer: pathophysiology and treatment. …

New dimensional staging of bisphosphonate-related osteonecrosis of the jaw allowing a guided surgical treatment protocol: long-term follow-up of 266 lesions in neoplastic and osteoporotic patients from the university of bari.

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is the most serious side effect in patients receiving bisphosphonates (BPs) for neoplastic disease and osteoporosis. The aim of this study is to propose a new dimensional stage classification, guiding the surgical treatment of BRONJ patients, and to evaluate the success rate of this new management. From 2004 to 2013, 203 neoplastic and osteoporotic patients with 266 BRONJ lesions were referred to the Odontostomatology Unit of the University of Bari. All patients underwent surgery after suspension of BPs therapy and antibiotic treatment. T

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… The histological examination was carried out using Nikon Eclipse E600 microscope (Nikon Corporation, Tokyo, Japan), equipped with Argon and Helio-Neon lasers, emitting at 488 nm and 543 nm wavelengths, which allows both optical and confocal laser scanning microscope (CLSM) analysis. …

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty.

BACKGROUND: Glaucoma is the international leading cause of irreversible blindness. Intraocular pressure (IOP) is the only currently known mo … ly one of the included trials used selective laser trabeculoplasty (SLT); the remaining trials used argon laser trabeculoplasty (ALT). Risk of bias issues were primarily in detection bias, reporting bias, and other potential bias due to studies funded by industry. Two potentially relevant studies are awaiting classification due to needing translation.In …