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Lewis Acid-Catalyzed Synthesis of Polysubstituted Furans from Conjugated Ene-yne-ketones and 1,3,5-Triazinanes.

An efficient and metal-free approach to the construction of diverse functionalized furan derivatives has been developed from ene-yne-ketones and 1,3,5-triazinanes. As an atom-economical and environment-friendly protocol, the new conditions are suitable for selective C-N and C-O bond formation of a wide range of polysubstituted furans in one pot.

Alternative Protein Systems: A Bibliometric and Comparative Review of Sustainability, Functionality, and Future Food Systems.

The growing demand for sustainable protein sources has accelerated the development of plant-based, microbial, cultivated, and insect proteins. This review combines a systematic analysis of Scopus-indexed publications with bibliometric mapping in Biblioshiny and VOSviewer and a comparative synthesis across environmental, economic, technological, nutritional, and social dimensions. The bibliometric results show a shift from technology-specific studies toward sustainability, circular bioeconomy, life-cycle assessment, consumer acceptance, and protein-transition research. No platform consistently

Analysis of heterogeneity of the different health technology assessment reports produced on the transcatheter aortic valve implantation in patients with severe aortic valve stenosis at low surgical risk.

BACKGROUND: Symptomatic severe aortic stenosis is a congenital or acquired aortic valve disease that occurs when the aortic valve of the heart narrows. It represents the most common valvular disease in adults and generally has a degenerative nature. Transcatheter aortic valve implantation (TAVI), due to its non-invasive approach, has become the standard treatment in patients who are ineligible to surgery or at high surgical risk, and it is also increasingly being performed in patients at intermediate to low surgical risk. The aim is to analyze the heterogeneity and explore the limitations of c

Harnessing the potential of lignocellulosic biomass for biofuels production.

Currently, fossil fuels are the main and dominant sources for producing fuels and commodity chemicals. The rising demand for fossil fuels continues to entrench global dependency on non-renewable sources creating the climate risk, the economic instability and sustainability challenges. Hence, there is a need to shift towards globally available, sustainable and renewable resources such as lignocellulosic biomass (LCB) that offers a sustainable pathway for producing biofuels and chemicals. Though various technologies are available for LCB conversion to biofuels and chemicals, scaling up of bioref

Reduction in NO(x) emission trends over China: regional and seasonal variations.

We analyzed satellite observations of nitrogen dioxide (NO2) columns by the Ozone Monitoring Instrument (OMI) over China from 2005 to 2010 in order to estimate the top-down anthropogenic nitrogen oxides (NOx) emission trends. Since NOx emissions were affected by the economic slowdown in 2009, we removed one year of abnormal data in the analysis. The estimated average emission trend is 4.01 ± 1.39% yr(-1), which is slower than the trend of 5.8-10.8% yr(-1) reported for previous years. We find large regional, seasonal, and urban-rural variations in emission trends. The average NOx emission trend

Integrated zoning of wellness tourism resources and economic valuation of summer-retreat wellness climate resources in mountainous cities: a case study of Chongqing, China.

Mountainous regions hold considerable wellness tourism potential, backed by abundant ecological and climatic resources. Yet research has largely focused on spatial zoning rather than linking spatial patterns to the economic valuation of ecological resources. This gap constrains evidence-based planning and hinders effective industrial conversion of ecological products. This study therefore develops an integrated framework that combines citywide wellness tourism resource zoning with Gross Ecosystem Product (GEP)-based economic valuation, using Chongqing, China, as a case study. We constructed a

Who is Anaemic in India? Intersections of class, caste, and gender.

Anaemia severely impacts physical and mental abilities, raises health risks, and diminishes the quality of life and work capacity. It is a leading cause of adverse pregnancy outcomes and maternal mortality, especially in developing nations like India, where recent data on anaemia from National Family and Health Survey (NFHS-4) (2015-16) and NFHS-5 (2019-21) indicate a tremendous rise. Anaemia is a marker of poor nutrition and health, and socio-economic factors such as gender norms, race, income, and living conditions influence its impact. As a result, there are disparities in how anaemia affec

An experimental investigation of a water desalination unit using different microparticle-coated absorber plate: yield, thermal, economic, and environmental assessments.

This study aims to augment the performance of a solar desalination unit. To experimental examine this idea, a modified solar still with three different microparticles doped in black paint-coated absorber were designed, fabricated, and tested in Jaipur, India. Three different microparticles such as copper, aluminum, and tin with particle size of 50-80 μm with weight concentration of 10% were doped in black paint and then coated on the absorber of solar still. The coated absorber of solar still were compared with the conventional solar still without any microparticle coating to obtain the effect

Impact of substandard and falsified antimalarials in Zambia: application of the SAFARI model.

BACKGROUND: Many countries are striving to become malaria-free, but global reduction in case estimates has stagnated in recent years. Substandard and falsified medicines may contribute to this lack of progress. Zambia aims to eliminate their annual burden of 1.2 million pediatric malaria cases and 2500 child deaths due to malaria. We examined the health and economic impact of poor-quality antimalarials in Zambia. METHODS: An agent-based model, Substandard and Falsified Antimalarial Research Impact (SAFARI), was modified and applied to Zambia. The model was developed to simulate population cha

Нарушение зрения и слепота взрослых - обзор распространенности и причин в Саудовской Аравии.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Крупное социально-экономическое развитие в Саудовской Аравии повлияло на структуру и причины нарушения зрения за последние 40 лет. Кроме того, актуализированное резюме имеющихся данных имеет жизненно важное значение для планирования, мониторинга и оценки национальной программы профилактики слепоты. АИМ: Это исследование, проведенное с целью дать краткий обзор распространенности, причин и изменений в структуре слепоты и нарушения зрения среди взрослых саудовцев за последние 40 лет с кратким обсуждением соответствующих социально-экономических и экологических факторов. МЕТО

Совпадение в аннотации оригинала
BACKGROUND: A major socio-economic development in Saudi Arabia affected the pattern and causes of visual impairment for the past 40 years. Moreover, an up-to-date summary of available data is vital for planning, monitoring, and evaluating national blindness prevention program. AIM: This study conducted to provide a summary overview of prevalence, causes, an…

The comparison of outcome and cost of three protocols for childhood non-high risk acute lymphoblastic leukemia in China.

OBJECTIVE: To compare the outcome and treatment cost of three protocols for childhood non-high risk acute lymphoblastic leukemia (ALL), and evaluate the feasibility of less intensive treatment protocol for low income families. METHODS: Two hundred forty-three children were newly diagnosed ALL in a university hospital from May 1999 to August 2006. Three protocols were offered to the patients: China-98 protocol, or modified ALLIC BFM2002 protocol, or an in-house Reduced Intensity Protocol (or also known as Economic Protocol). RESULTS: Among 243 patients, 19 abandoned treatment, 3 transferred t

[Research progress of free ammonia pretreatment in sewage sludge anaerobic fermentation for resource recovery and hazardous substance removal].

Direct anaerobic fermentation of sewage sludge is often inefficient for the recovery of high-value products such as short-chain fatty acids, hydrogen, and methane, as well as for the simultaneous removal of hazardous substances like hydrogen sulfide, pathogens, and antibiotic resistance genes. Free ammonia (FA), a substance that can be obtained internally within wastewater treatment systems, exhibits environmental friendliness, cost-effectiveness, and sustainability, showing promising prospects in achieving sludge resource recovery and hazardous substance removal. This paper systematically rev

Planning for the Post-COVID Syndrome: How Payers Can Mitigate Long-Term Complications of the Pandemic.

As the COVID-19 pandemic continues to unfold, payers across the USA have stepped up to alleviate patients' financial burden by waiving cost-sharing for COVID-19 testing and treatment. However, there has been no substantive discussion of potential long-term effects of COVID-19 on patient health or their financial and policy implications. After recovery, patients remain at risk for lung disease, heart disease, frailty, and mental health disorders. There may also be long-term sequelae of adverse events that develop in the course of COVID-19 and its treatment. These complications are likely to pla

European guidance for the diagnosis and management of osteoporosis in postmenopausal women.

Guidance is provided in a European setting on the assessment and treatment of postmenopausal women at risk from fractures due to osteoporosis.IntroductionThe International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2013. This manuscript updates these in a European setting.MethodsSystematic reviews were updated.ResultsThe following areas are reviewed: the role of bone mineral density measurement for the diagnosis of osteoporosis and assessment of fracture