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Osteomas of the maxillofacial district: endoscopic surgery versus open surgery.

Maxillofacial district osteomas are benign lesions with very slow growth. The most frequent localization is the frontal sinus, about 57% of all paranasal cavity osteomas; less frequently, they can be located in the ethmoidal sinus or sphenoidal and maxillary. Etiology has not completely clarified yet; nevertheless, there are 3 main pathogenetic theories: osteogenic, traumatic, and infective. Open procedures represent the gold standard, but there is still an unsolved debate for the best treatment option. Endoscopic techniques offer an alternative approach, enabling closer and more direct visual

Anatomy, histology, and nerve density of clitoris and associated structures: clinical applications to vulvar surgery.

BACKGROUND: A precise understanding of structures comprising the female external genitalia is essential in obstetric and gynecologic practic … he medial surface of the inferior pubic ramus surrounded by a dense fibrous capsule adherent to the periosteum. The nerve and artery then coursed deep to dense connective tissue layers, which were contiguous with the suspensory ligament and fascia of the clitoris. Histologic examination revealed the presence of erectile tissue in the clitoral body, crura, an …

[Treatment of the complex intraarticular fracture of the distal humerus with the latitude elbow prosthesis].

OBJECTIVE: Therapy of comminuted intraarticular distal humerus fractures in elderly patients with primary total elbow arthroplasty to achiev … e distal humerus, capsule and proximal ulna. Reflection of the triceps in continuity with the ulnar periosteum and the forearm fascia. Attempt at reconstruction of the epicondyles to achieve ligamentary stability and to implant an unlinked prosthesis. If this is technically not possible, the prosthesis is linked at the end of the operation. Removal of the di …

Temporal expression patterns of BMP receptors and collagen II (B) during periosteal chondrogenesis.

Articular cartilage has a limited ability to repair itself. Periosteal grafts have chondrogenic potential and are used clinically to repair defects in articular cartilage. An organ culture model system for in vitro rabbit periosteal chondrogenesis has been established to study the molecular events of periosteal chondrogenesis in vitro. In this model, bone morphogenetic protein-2 (BMP2) mRNA expression was found to be upregulated in the first 12 h. BMPs usually transduce their signals through a receptor complex that includes type II and either type IA or type IB BMP receptors. Receptors IA and

[Discogenic low back pain and degenerative lumbar spinal stenosis - how appropriate is surgical treatment?].

Surgery in acute and/or chronic low back pain is still a matter of intensive and controversial discussions. A vast number of minimally invas … usually nociceptors in the cartilaginous endplates, in the outer anulus fibrosus as well as in the periosteum of the vertebral bodies. Clinical symptoms correlate with morphologic changes detected with MR-imaging (modic type I) or with contained disc protrusions mainly without neurological symptoms. Surgery is rarely indicated, spontaneous remissions occur …

Teaching the Basics: Development and Validation of a Distal Radius Reduction and Casting Model.

BACKGROUND: Approximately one-third of reduced pediatric distal radius fractures redisplace, resulting in further treatment. Two major modif … re model was created with radiopaque bony segments and articulating elbows and shoulders. Simulated periosteum and internal deforming forces required proper reduction and casting techniques to achieve and maintain reduction. The forces required were estimated through an iterative process through feedback from experienced clinicians. Embedded monofilaments al …

Synergetic effects of hBMSCs and hPCs in osteogenic differentiation and their capacity in the repair of critical-sized femoral condyle defects.

Tissue-engineered bone grafts require an osteoblastic cellular source to be utilized in bone transplantation therapy. Human bone marrow stem cells (hBMSCs) and periosteal-derived stem cells (hPCs) are the commonly used cellular sources for bone tissue engineering and are essential in fracture healing. In the present study, hBMSCs and hPCs were co-cultured from the same donors, as the cellular source. In monolayer cultivation, co-culturing hBMSCs and hPCs demonstrated more robust mineralized nodule formation and stronger alkaline phosphatase (ALP) positive staining than hBMSCs or hPCs. Three-di

[One hundred years of bone surgery in the Lyons Teaching Hospitals (1897-1997)].

Throughout the XIXth century and until 1945, bone surgery focused primarily on correcting deformities in children. The treatment of injury-r … liantly applied the method developed by Claude Bernard to the experimental study of the role of the periosteum. He observed that new bone was laid down after "subperiosteal resection" of infected bone or joint tissue. His technique allowed to reduce dramatically the number of limb amputations for infection. In 1897, in addition to Ollier (who died in 1900), …

Biodegradable miniplates (LactoSorb): long-term results in infant minipigs and clinical results.

Metallic plates are known for their passive intraosseous transmission in the growing skull. To avoid plate removal, resorbable material with strength comparable to that of metallic plates and predictable resorption would be desirable. This should be accomplished without causing inflammatory complications and foreign body reactions often seen with highly crystalline poly-L-lactic acid or pure polyglycolic acid implants. In an animal experiment in four young Göttingen minipigs, the resorbable poly-L-lactic acid/polyglycolic acid copolymer LactoSorb was tested previously. In addition to testing t

Sandwich Allograft for Long-Bone Deformity Correction in Bone Dysplasia.

BACKGROUND: The "sandwich allograft" technique is indicated for correction of long-bone deformity in patients with osteogenesis imperfecta ( … l as the correct type of internal fixation. The nonunion site is exposed circumferentially, and the periosteum is elevated. In instances in which there is previous intramedullary fixation, the implant should be assessed for any migration or breakage, which would warrant removal. New intramedullary fixation is then performed to align the bone ends at the nonu …

Endoscopic Endonasal Approach to Multilobular Giant Pituitary Adenoma with Cavernous Sinus Invasion and Petroclival Extension.

Giant pituitary adenomas are considered a surgical challenge. Their invasiveness, irregular growth, and extensions make this surgery critica … r the space and remove the tumor inside the cavernous sinus as much as possible. 3:54: Removing the periosteum covering the sellar floor makes us reach the posterior clinoidal process. In order to gain an access to petroclival regoin inferior wall of sellar floor drilled out and middle and posterior clinoidal processes were removed by drilling. Removal of an …

Orbital blow-out fractures: correlation of preoperative computed tomography and postoperative ocular motility.

BACKGROUND/PURPOSE: Although the management of orbital blow-out fractures was controversial for many years, refined imaging with computed to … idual diplopia 6 months after surgery. A fine network of fibrous septa that functionally unites the periosteum of the orbital floor, the inferior fibrofatty tissues, and the sheaths of the inferior rectus and oblique muscles was demonstrated by Koornneef. Entrapment between bone fragments of any of the components of this anatomic unit can limit ocular motili …

Advance in the application of organoids in bone diseases.

Bone diseases such as osteoporosis and osteoarthritis have become important human health problems, requiring a deeper understanding of the pathogenesis of related diseases and the development of more effective treatments. Bone organoids are three-dimensional tissue masses that are useful for drug screening, regenerative medicine, and disease modeling because they may mimic the structure and physiological activities of organs. Here, we describe various potential methods for culturing bone-related organoids from different stem cells, detailing the construction processes and highlighting the main

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… cells (hPDCs), which are obtained from the periosteum and are notable for their potential in bone and cartilage regeneration. … Zinc sulfate stimulates osteogenic phenotypes in periosteum-derived cells and Co-cultures of periosteum-derived cells and THP-1 cells . Life 11 , 410 . 10.3390/life11050410 33946199 PMC8144993 Park Y. Cheong E. Kwak J.-G. Carpenter R. Shim J.-H. Lee J. ( 2021 ). …

Modified Dunn Procedure for Open Reduction of Chronic Slipped Capital Femoral Epiphysis.

BACKGROUND: Abnormal femoral head anatomy following moderate-to-severe slipped capital femoral epiphysis (SCFE) can lead to femoroacetabular … the level of the femoral neck by subperiosteal bone removal performed in an inside-out manner. The periosteum of the femoral neck is gradually elevated. The resulting soft-tissue flap, consisting of the retinaculum and external rotators, holds the blood vessels supplying the epiphysis. The femoral epiphysis is pinned in situ (in unstable cases) with threade …

In Vivo Bone Tissue Engineering Strategies: Advances and Prospects.

Reconstruction of critical-sized bone defects remains a tremendous challenge for surgeons worldwide. Despite the variety of surgical techniques, current clinical strategies for bone defect repair demonstrate significant limitations and drawbacks, including donor-site morbidity, poor anatomical match, insufficient bone volume, bone graft resorption, and rejection. Bone tissue engineering (BTE) has emerged as a novel approach to guided bone tissue regeneration. BTE focuses on in vitro manipulations with seed cells, growth factors and bioactive scaffolds using bioreactors. The successful clinical

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… As mentioned earlier, the first introduction of the IVB concept was based on the use of the periosteum cambial layer as the source of progenitor cells for bone regeneration [ 182 ]. … This approach provides an intrinsic axial blood supply, while the osteogenic surface of the periosteum can be located inside the scaffold [ 207 ]. …

Impact of recombinant human bone morphogenetic protein-2 on residual ridge resorption after tooth extraction: an experimental study in the rat.

Residual ridge resorption begins following tooth extraction and continuously reduces alveolar bone volume, potentially creating a significant problem in dental implant treatment. In this study, the role of recombinant human bone morphogenetic protein-2 (rhBMP-2) in residual ridge resorption after tooth extraction was investigated. A polylactic acid/polyglycolic acid copolymer-coated gelatin sponge carrier was implanted with or without rhBMP-2 (1 microg) in the mesial root sockets after removal of maxillary first molars in male Wistar rats. Fine structural and histomorphologic analyses were con

The effect of rabbit skeletal muscle on the large segment autologous bone ectopic preconstruction of vascularized bone flap.

AIM OF THE STUDY: To investigate the spatiotemporal secretion patterns of vascular endothelial growth factor (VEGF) and bone morphogenetic p … ibroconnective tissues wrapping the bone segment mimicked the thickness and tightness of the native periosteum, showing resistance to separation. 2. Histological Analysis (H&E Staining). Progressive bone tissue repair was observed in the experimental group: Week 2: Minimal fibrous granulation tissue on the bone surface and within the lumen. Week 4: Emergence …

Дополнительная ценность МРТ ZTE для оценки диабетического заболевания ног.

:: Анализ дополнительной ценности Zero МРТ " Эхо времени " (ZTE) по сравнению со стандартным протоколом МРТ для обнаружения многочисленных изменений в диабетической ступне. Для сравнения эффективности ZTE с КТ для выявления многочисленных аномалий и оценки воспроизводимости данных между наблюдателями с использованием коэффициента каппы Коэна. 46 (больные)33 мужчины, 13 женщины; средний возраст, 64 годы) с клинически подтвержденным сахарным диабетом и клинически предполагаемыми диабетическими осложнениями ног. Стандартный протокол МРТ, включающий последовательность ZTE, был выполнен в

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… Periosteal reaction Reactive new bone formation along the periosteum in response to infection or trauma. … Periosteal reaction Reactive new bone formation along the periosteum in response to infection or trauma. …

Neurophysiological mechanisms of cancer-induced bone pain.

BackgroundCancer-induced Bone Pain (CIBP) is an important factor affecting their quality of life of cancer survivors. In addition, current clinical practice and scientific research suggest that neuropathic pain is a representative component of CIBP. However, given the variability of cancer conditions and the complexity of neuropathic pain, related mechanisms have been continuously supplemented but have not been perfected.Aim of reviewTherefore, the current review highlights the latest progress in basic research on the field and proposes potential therapeutic targets, representative drugs and u

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… The pathophysiological basis of hyperalgesia involves the proliferation of nerve fibers within the bone marrow, bone and periosteum. Cancer cells induced sensory in sympathetic nerve fibers reorganization and proliferation in the periosteum. … In addition, an abundance of nerve fibers in the bone marrow, bone and periosteum and cancer cells can induce sensory and sympathetic nerve fibers in the periosteum to produce and reorganize. …

The effect of denosumab vs. zoledronic acid in preventing skeletal-related events, including pain-related bone metastasis: a systematic review.

PURPOSE: Skeletal-related events (SREs) are common complications of bone metastases that include the need for radiation or surgery to bone, pathological and radiological fractures, and hypercalcemia. Available data indicate that significant bone pain is associated with SREs, leading to an increased risk of death, higher medication costs, and reduced quality of life for patients. Bisphosphonate agents and denosumab are therapeutic options for preventing SREs in advanced cancer patients with bone metastases. This study aims to compare the effect of denosumab and zoledronic acid in SREs, with a p

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… Pain associated with bone cancer typically originates from areas densely populated with nerve endings, such as the periosteum, spinal cord, and cortical bone, with a nerve fiber ratio of 100 : 2 : 0.1. … The periosteum, which has sympathetic innervation and a high density of sensory fibers, including A-δ fibers and C fibers, plays a crucial role in this pain [ 3 , 4 ]. The pain is often described as dull and persistent but can intensify as bone remodeling progresses. …