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[Neurological disorders secondary to vitamin B12 deficiency: about 29 cases].

Neurological disorders secondary to vitamin B12 deficiency are polymorphic and diverse. There have been very few studies conducted in the Moroccan as well as in the African population. This study aims to describe the clinical, paraclinical, evolutionary features of neurological manifestations in patients with vitamin B12 deficiency within the Department of Neurology at the Moulay Ismail Military Hospital, Meknes over a period of 18 years (1999-2017). The study involved 06 women and 23 men, with an average age of 57 years. The mean time between symptom onset and diagnosis was 3 months. Neurolog

[Acute polyneuropathies in a hospital in the south of Spain: ten years' experience].

INTRODUCTION: Guillain-Barre syndrome is the most frequent cause of acute flaccid paralysis in children. AIM: To describe the characteristics of patients diagnosed with acute polyneuropathies and their long-term progress. PATIENTS AND METHODS: We conducted a retrospective descriptive analysis of children under 14 years of age admitted to our hospital between January 2004 and December 2014. Clinical, demographic and neurophysiological variables were collected together with other imaging tests. RESULTS: Twenty-six patients, with a mean age of 3.83 years, were diagnosed with acute polyneuropat

A homozygous AHI1 gene mutation (p.Thr304AsnfsX6) in a consanguineous Moroccan family with Joubert syndrome: a case report.

INTRODUCTION: Joubert syndrome is a rare congenital disorder characterized by brain malformation, developmental delay with hypotonia, ocular motor apraxia, and breathing abnormalities. Joubert syndrome is a genetically highly heterogeneous ciliopathy disorder with 23 identified causative genes. The diagnosis is based on brain imaging showing the "molar tooth sign" with cerebellar vermis agenesis. We describe a consanguineous Moroccan family with three affected siblings (18-year-old boy, 13-year-old girl, and 10-year-old boy) showing typical signs of Joubert syndrome, and attempt to identify th

Monoclonal gammopathies in a Moroccan military hospital.

The aim of this study was to describe biological features and aetiology of monoclonal gammopathy diagnosed during a 10-year period in the biochemistry department of the Moroccan Military Hospital Mohamed V in Rabat. The study was performed from 1 January 2000 to 31 December 2009. The records of 261 patients living in the Rabat area in which either serum protein electrophoresis and serum and/or urine immunofixation were performed at the biochemistry department of Military Instruction Hospital in Rabat were analysed. A cohort of 182 (70%) men and 79 (30%) women, the mean ± SD (range) ages were 6

Factors influencing the awareness of diabetic foot risks.

INTRODUCTION: The aim of the present study was to identify factors influencing diabetic patients' awareness of the risk of foot problems. METHODS: We performed a prospective study of diabetic patients hospitalized or seen in consultation. Various factors were analyzed in order to identify those related to the patients' level of awareness of risk factors in diabetic foot. RESULTS: Ninety-one patients were included (mean age: 48; male/female gender ratio: 0.63). Over 50% of the study population was not aware of the risks of diabetic foot. Educational level and socioeconomic status had an impac

[Oculo-cerebro-renal Lowe syndrome: clinical, biochemical and molecular studies in a Moroccan patient].

The oculo-cerebro-renal syndrome of Lowe is a rare X-linked disorder, caused by the inositol biphosphate 5-phosphatase deficiency, localized to the Golgi complex. Several mutations were reported in patient's OCRL gene leading to enzyme deficiency. We report a Moroccan case of OCRL syndrome of Lowe with a neo mutation in exon 10. The patient aged of 19 months was referred to our medical centre because of a psychomotor retardation. He had a medical history of eye abnormalities including cataract and bilateral glaucoma, diagnosed when he was 5 weeks old. Cataract has been treated after chirurgica

[Cervical hydatid disease with retropharyngeal involvement: a case report].

Hydatid disease involves the bones in 0.5 to 2% of cases, with 44% of these cases at the level of the spine. The cervical spine is a rare location, with a risk of spinal cord compression and recurrences. The Authors report a case of a young male admitted for progressive quadriplegia secondary to cervical spine hydatidosis, extending towards the retropharynx that was evaluated by CT and MRI.

Thoracic rupture of hepatic hydatidosis (123 cases).

BACKGROUND: Hydatid disease is frequently endemic in countries with poor environmental sanitation and in geographic areas where interaction between humans and animals is common. Pulmonary complications result from the proximity of hydatid cysts in the liver and the diaphragm. METHODS: The medical records of 123 patients, with established hydatid disease manifesting abnormal chest roentgenograms, were retrospectively analyzed for the period January 1990 to December 1999. RESULTS: Chest roentgenogram and abdominal ultrasound provided a correct preoperative diagnosis in 108 patients (87.8%). Ex

Cardiovascular Comorbidities in Knee Osteoarthritis: Prevalence, Functional association, and Therapeutic Consequences.

BACKGROUND: Knee osteoarthritis (KOA) is a common chronic degenerative joint disease and a leading cause of pain, disability, and impaired q … lly confirmed KOA attending the Rheumatology A outpatient clinic at El Ayachi Hospital, Rabat-Salé, Morocco. Adults with inflammatory arthritis, previous major knee surgery, or post-traumatic osteoarthritis were excluded. Data collected included age, sex, disease duration, pain assessed by the visual analog scale (VAS), functional disability measured by t …

Evaluation of the phytochemical profile, biological activities, and acute toxicity of Cistus ladanifer aerial part extracts: experimental and in silico investigations.

INTRODUCTION: Using both experimental and in silico approaches, this study aimed to evaluate the phytochemical composition and biological activities of Cistus ladanifer aerial part extracts. METHODS: Cistus ladanifer aerial parts were collected in the Khenifra region, Morocco. Hydroethanolic (Soxhlet) and aqueous (decoction) extracts were prepared. Physicochemical parameters, mineral content (ICP-AES), phytochemical screening, total polyphenols, flavonoids, and condensed tannins were determined. HPLC/UV-ESI-MS was used for chemical profiling. Antioxidant activity was assessed by TAC, DPPH, an…

Determinants affecting the quality of sexual life among older adults in Africa: a scoping review.

BACKGROUND: Older adults (people aged >60 years) are often stereotyped as being asexual, reflecting a broader lack of research into the sexu … four quantitative articles. Four studies were conducted in Nigeria, and one each from South Africa, Morocco and Tanzania. Our review identified four categories of determinants influencing the quality of sexual life among older adults in Africa: psychological, sociocultural, physiological and health. Psychological determinants, including past trauma, perfo …

Monogenic Neonatal Diabetes: Clinical Presentations, Genetic Findings, and Response to Therapy in a Retrospective Case Series.

Introduction Monogenic neonatal diabetes mellitus (NDM) is a rare form of diabetes, presenting within the first six months of life and cause … d in the Pediatric Endocrinology Unit of the Abderrahim Harouchi Mother-Child Hospital, Casablanca, Morocco, between January 2018 and December 2025. Clinical presentation, biochemical data, insulin requirements, genetic results, and outcomes were extracted from medical records. Genetic testing was performed through next-generation sequencing (NGS), or tar …

Obesity and Impaired Male Fertility: An Association of Clinical Importance.

BACKGROUND: Male infertility is a major contributor to couple infertility, and increasing evidence suggests that excess body weight may adve … nfertility at the Medically Assisted Reproduction Center of Mohammed VI University Hospital, Oujda, Morocco. Patients were classified into three BMI groups: normal BMI, overweight, and obese. Semen analysis was assessed according to World Health Organization criteria. Quantitative and qualitative semen abnormalities were recorded and compared across BMI g …

Combined FMEA and Cause-Effect Analysis Method for Risk Assessment of Failures Impacting Hemodialysis Water Quality.

INTRODUCTION: Hemodialysis patients are exposed weekly to large volumes of dialysis water, making water quality a critical determinant of pa … ent was conducted at the hemodialysis water treatment unit of Hassan II University Hospital in Fez, Morocco. The production chain was divided into four subprocesses: water feeding, pretreatment, treatment, and distribution. Potential failures, causes, and effects were identified through brainstorming sessions and root-cause analysis using an Ishikawa diag …

Клиническая характеристика венозного тромбоэмболизма и применимости ThroLy и IMPEDE VTE рисков для пациентов с лимфомой и множественной миеломой: Ретроспективное исследование марокканского одиночного центра.

Венозный тромбоэмболизм (VTE), охватывающий тромбоз глубокой вены (DVT) и легочную эмболию (PE), является одним из основных осложнений у пациентов с гематологическими заболеваниями и вносит существенный вклад в заболеваемость и смертность. Пациенты с лимфомой и множественной миеломой особенно уязвимы из-за связанных с болезнями и лечением протромботических факторов. Для выявления пациентов, подверженных повышенному тромбозовому риску, были разработаны модели оценки рисков, в том числе показатель тромбоза в лимфоме (Трули) и показатель VTE IMPEDE. Цель этого исследования состояла в том, чтобы о

Совпадение в аннотации оригинала
Background Venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT) and pulmonary embolism (PE), is a major complication in pat … alytical study in the Department of Clinical Hematology at Moulay Ismail Military Hospital, Meknes, Morocco, between September 2023 and September 2025. A total of 141 patients were included, comprising 72 patients with lymphoma and 69 patients with multiple myeloma. Clinical, demographic, treatment-related, and thrombotic data were collected from medical …

What predicts adolescents' mathematics anxiety in the Middle East and North Africa? An interpretable machine learning analysis of six Arab education systems in PISA 2022.

INTRODUCTION: Mathematics anxiety is among the most consequential affective barriers to mathematics learning, yet large-scale evidence from … r-old students from the six participating Arab education systems: the United Arab Emirates, Jordan, Morocco, Palestine, Qatar, and Saudi Arabia. Six algorithms (linear regression, elastic net, random forest, AdaBoost, XGBoost, and LightGBM) were tuned with randomized search under 5-fold cross-validation to predict the PISA mathematics anxiety index (ANXMA …

Numerical simulation of oil spill dispersion and weathering in the Alboran Sea: A case study of its North-Eastern Coast.

Accidental oil spills in the Alboran Sea represent a high-risk hazard because intense maritime traffic, semi-enclosed circulation, and sensi … cous oils, rapid protection of lagoon inlets where feasible, and transboundary coordination between Morocco and Algeria.

Mediastinal Lymphadenopathy: Associations Between Computed Tomography Characteristics and Final Etiological Diagnoses in 200 Patients.

BACKGROUND: Despite recent technological advances in the diagnostic evaluation of mediastinal lymphadenopathy, access to advanced diagnostic procedures remains limited in our setting. OBJECTIVE: This study aimed to describe the etiological profile of mediastinal lymphadenopathy and to assess the statistical associations between computed tomography (CT) characteristics of mediastinal lymph nodes and final etiological diagnoses. MATERIALS AND METHODS: This retrospective observational study was conducted in the Department of Pulmonology at Moulay Youssef University Hospital, Salé, Morocco, over…

Mortality rate and predictors of mortality of pediatric sepsis and septic shock in a Moroccan tertiary care center.

BACKGROUND: Sepsis is the leading cause of child mortality worldwide. Pediatric sepsis-related mortality in Africa is estimated to be as hig … , respectively, with acceptable calibration. CONCLUSION: Our research assessed pediatric sepsis in Morocco, a lower-middle-income North African country. Mortality rates were higher compared to high-income countries. The pSOFA score was effective in predicting severity and mortality. Lower platelet count, vasopressor use, and mechanical ventilation were i …