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Myelopathies in Ethiopia.

From December 1990 to December 1993, 130 patients who had a lesion localized to the spinal cord were admitted to the Tikur Anbessa Hospital, … %, 54% and 14% of the cases respectively. Tuberculous spondylitis was found to be the leading cause accounting for 35 (26.9%), and HIV-1 myelopathies was the second common type accounting for 22 (16.9%) of spinal cord disease. Metastatic cord compression, tropical spastic paraparesis, (progressive non compressive myelopathy), cervical spondylosis, primary co …

Global vaccine research and application hotspots and trends: a systematic bibliometric analysis based on SCIE highly cited papers.

OBJECTIVES: COVID-19, a public health emergency affecting the world in 2019, not only greatly promoted the development and application of va … of highly cited papers in the field of vaccine research increased significantly from 2020 to 2024, accounting for 76.12%. The number of highly cited papers for vaccines peaked in 2021 and 2022, followed by a rapid decline. Highly cited papers came from 7133 institutions in 153 countries, and the most influential country in the field of vaccines was the USA, …

Transportable inference using target population summary statistics under covariate shift.

Transporting findings from a study population to a target population is central to evidence-based decision-making in real-world settings. Mo … evelop a new transportability method that allows more flexible modeling of covariate shift, thereby accounting for covariate shift and uncertainty in covariate summaries simultaneously. Asymptotic normality for the proposed estimator is established, and its asymptotic variance is consistently estimated. The proposed method offers greater flexibility in accou …

The relationship between perceived stress, psychological resilience, and depressive symptoms in college students, and the moderating role of gender.

This study explored the mediating role of multiple dimensions of psychological resilience in the relationship between perceived stress and d … direct effects of perceived stress on depressive symptoms were both significant, with direct effect accounting for 81.28%. The mediating effect of tenacity was also significant, accounting for 18.72% of the total effect. Gender moderated the direct path from perceived stress to depressive symptoms and from tenacity to depressive symptoms. Women showed signif …

The dynamics of loneliness: Longitudinal associations of anhedonia and dampening in a clinical sample of depressed individuals.

The longitudinal relationship between loneliness and depressive symptoms is well documented. However, few studies have considered the bidire … ltilevel models revealed that within-person loneliness predicted decreased next-week anhedonia when accounting for within-person and between-person variation in anhedonia. Within-person anhedonia predicted greater next-week loneliness when accounting for autoregressive effects. Moderation results revealed that at higher levels of loneliness, the association …

Interpersonal Contributors to Depression in Sexual Minority Adolescents: An Examination of Exposure to Acute Stressors and Neural Reactivity to Interpersonal Emotional Images.

Sexual minority (SM) adolescents are at a higher risk of depression compared to their heterosexual peers, indicating a need for multimethod … iation between SM identity and depressive symptoms, and (3) whether these interactions persist when accounting for disparities in exposure to recent interpersonal stressors. SM adolescents reported higher depressive symptoms and were exposed to more severe recent peer (but not family) stressors than heterosexual adolescents. LPP responses to both positive an …

Quantifying the sensitivity limit of ICG imaging in the presence of tissue autofluorescence.

SIGNIFICANCE: Fluorescent imaging (FI) using indocyanine green (ICG) is a powerful tool in medical diagnostics and surgery. Although numerous studies have focused on optimizing injection protocols and suppressing excitation light leakage, tissue autofluorescence has not been widely recognized as a fundamental factor limiting sensitivity. AIM: We aim to quantitatively determine the sensitivity limit for ICG detection in biological tissues, accounting for background signals from both scattered excitation light and tissue autofluorescence. APPROACH: We combine experiments on tissue phantoms wit…

The importance of Spanish-language similarity in friend selection.

The present study was designed to disentangle the contributions of Spanish-language similarity and Hispanic background in the selection of s … to be nominated as friends when both the target and the nominator spoke Spanish at home, even after accounting for the contribution of shared Hispanic background. In contrast, after accounting for the contribution of shared Spanish language, targets were not more likely to be nominated as friends when both the target and nominator reported a Hispanic backgro …

Rhizodeposition Drives One Third of Belowground Carbon Input in Agroecosystems.

Soil carbon (C) accumulation, an important mitigation solution to climate change, critically depends on plant C inputs. However, the allocation of belowground C inputs between root biomass and labile rhizodeposits remains poorly quantified. By synthesizing 746 global observations using 13C/14C tracing, we reveal that 17% of plant assimilated C is allocated belowground, with rhizodeposition accounting for one-third of the net belowground C input. Legumes primarily allocate assimilated C to belowground via rhizodeposition, whereas other crops, including barley, wheat, rice, maize, and grasses, i…

Detection of emergent multiple predator effects in a warming world.

Predicting the influence of predators on food webs remains challenging, particularly when multiple predator species share a common prey spec … creased temperature differentially enhanced predation in both predator species in isolation, and in accounting for this, we detected an emergent MPE in two-predator assemblages only at low temperatures (20°C). Our findings add to a growing body of research that suggests that the occurrence of MPEs may vary with temperature, while stressing the importance of …

A Hybrid LCA Framework for Drug-Level Carbon Footprint Assessment under Data Constraints: Application to Narrower-Spectrum Penicillin.

Understanding differences in drug-specific carbon footprints across countries is increasingly important as healthcare sustainability and pro … ic distribution differs markedly from that of aggregated pharmaceuticals, showing that sector-level accounting can mask substantial cross-country heterogeneity. Across alternative assumptions, global totals vary by less than 30%, and country rankings remain largely stable, indicating that the observed patterns reflect structural differences in consumption an …

Re-establishing and refining baseline neuropsychological test data among professional hockey players: part 2 regression-based adjustment of neuropsychological norms in professional hockey.

OBJECTIVE: To determine whether a regression-based approach provides a more appropriate normative framework for professional hockey players after accounting for estimated overall cognitive ability, language proficiency or acculturation, and baseline performance on other cognitive measures. METHODS: Players were randomly selected from club rosters to complete the National Hockey League/National Hockey League Players' Association (NHL/NHLPA) paper and pencil (PnP) concussion battery and English Proficiency Questionnaire (EPQ) during 2022-2023 and 2023-2024 pre-season camps (oversampling Primary…

Negative Urgency, Emotion Regulation, and Intimate Partner Violence Severity in High Risk Couples with Alcohol Use Disorders.

OBJECTIVE: Alcohol use problems and impulsivity predict intimate partner violence (IPV) perpetration. Adaptive cognitive emotion regulation skills may be a protective moderating factor in the relation between impulsivity and IPV perpetration. However, the relationships among impulsivity, adaptive emotion regulation, and IPV perpetration have rarely been studied in a dyadic context. This work examined the moderating influence of both actors' and their partners' adaptive emotion regulation skills on the relationship between impulsivity and IPV perpetration after accounting for alcohol use proble…

Emergy-Based Sustainability Evaluation and Optimization Scenarios for 341 Chinese Home-Cooked Dishes.

Chinese home-cooked dishes (CHCDs) link agricultural production and daily consumption, but their resource dependence and sustainability remain poorly quantified. We standardized 341 recipes from China's 34 provincial-level administrative regions, conducted a production-to-consumption analysis using emergy (solar-equivalent available energy directly and indirectly required for a product or service), and evaluated six optimization scenarios. Mean emergy input was 5.93 × 1012 sej·dish-1, with nonrenewable purchased inputs accounting for 77.99%. Ingredients, oil and sauces, and cooking contributed…

Установление на демографической основе нормативных значений для световой цепи нейрофильтрации и глиального фибрового кислотного белка в образцах сыворотки и плазмы.

ПОДСКАЗКА: Толкование уровней содержания в крови нейрофильтрованных световых цепочек (NfL) и глиевых фибровых кислотных белков (GFAP) требует исходных диапазонов от здоровых когорт с учетом демографических особенностей. ЦЕЛЬ: Сопоставление сыворотки и плазмы NfL и GFAP для здоровых людей с учетом возраста, пола и индекса массы тела (BMI). МЕТОДЫ: Подростки через пожилых людей были наняты на общественные мероприятия в Колорадо и в клинику для престарелых. Невролог просмотрел самопровозглашенные медицинские истории. Пробы сыворотки и плазмы EDTA были расценены с использованием Kuanterix SR-X Sim

Совпадение в аннотации оригинала
BACKGROUND: Interpretation of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) levels in blood requires reference ranges from healthy cohorts, accounting for demographic features. OBJECTIVE: To compare serum and plasma NfL and GFAP in healthy individuals, accounting for age, sex, and body mass index (BMI). METHODS: Adolescents thr…

Relationship between caregiver burden and family resilience among Chinese parents of children with autism spectrum disorder: The mediating role of social support and positive cognition.

PURPOSE: This study was designed to assess the impact of caregiver burden on family resilience and explore the potential mediating role of s … ively associated with family resilience, with social support partially mediating this relationship (accounting for 17.86 % of the total effect), and both factors being indirectly linked through social support and positive cognition (accounting for 3.76 % of the total effect). CONCLUSIONS: The findings emphasize the need for interventions aimed at enhancing …

Impact of quitline services on tobacco cessation: an application of modern epidemiologic methods.

This study investigated the effectiveness of quitline service intensity (high vs low) on past 30-day tobacco abstinence at 7-months' follow- … associated with abstinence (RR = 1.18; 95% CI, 1.04-1.34). The effect estimate was attenuated after accounting for censoring (RR = 1.14; 95% CI, 1.00-1.30). After adjusting for both baseline confounding and selection bias via IPTCW, high-intensity cessation services were associated with 1.23 times (95% CI, 1.08-1.41) the probability of abstinence compared to …

The Impact of Prior Incarceration on Cognitive Trajectories Among Older Adults: Evidence From the Health and Retirement Study.

OBJECTIVES: This study examines the association between prior incarceration and cognition trajectories among older adults in the United Stat … eper declines in cognitive functioning over time. However, these associations were attenuated after accounting for sociodemographic and health-related characteristics, and all associations were rendered statistically nonsignificant after accounting for educational attainment. DISCUSSION: These findings highlight poorer cognition among older formerly incarce …

Alexithymia predicts face emotion perception after acquired brain injury.

BACKGROUND: This study investigated the presence and level of alexithymia and examined the relationship between alexithymia and affect recognition abilities after acquired brain injury (ABI), accounting separately for etiology due to stroke or traumatic brain injury (TBI). METHODS: Ninety-nine neurologically healthy adults (NHA) and 119 adults with moderate-to-severe ABI (63 TBI, 56 stroke) participated. Main measures included the Toronto Alexithymia Scale-20 (TAS-20) and Multicultural Facial Emotion Perception Test (MFEPT). RESULTS: ABI groups endorsed greater alexithymia than NHA, but TBI …

Unifying Structure and Function Towards a Comprehensive Macular Evaluation in Eye Disorders: A Multi-Modal Approach Using Microperimetry and Optical Coherence Tomography.

OBJECTIVE: We present a new automatic and comprehensive framework to evaluate retinal sub-layer thickness and visual sensitivity at precise retinal locations through multi-modal registration of confocal scanning laser ophthalmoscope (cSLO) images obtained separately from an optical coherence tomography (OCT) device and a microperimeter. METHODS: We map consecutive B-scans onto the cSLO images after accounting for eye motion. Next, we coarsely register the SLO-microperimetry and cSLO-OCT images using SIFT, followed by precise elastic image registration. Subsequently, we ensure the quality of t…