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Computed tomography of the brain, hepatotoxic drugs and high alcohol consumption in male alcoholic patients and a random sample from the general male population.

Computed tomography (CT) of the brain was performed in a random sample of a total of 195 men and 211 male alcoholic patients admitted for the first time during a period of two years from the same geographically limited area of Greater Stockholm as the sample. The same medical, social and neuroradiological methods were used for examination of the alcoholic inpatients as for the random controls. Laboratory tests were performed, including liver and pancreatic tests. Toxicological screening was performed and the consumption of hepatotoxic drugs was also investigated and the following were the type

Anterior cruciate ligament reconstruction as an outpatient procedure.

During a 27-month period, 222 patients with 227 anterior cruciate ligament-deficient knees underwent arthroscopically assisted reconstructions as outpatient procedures. Bone-tendon-bone autografts were used for 169 of these reconstructions; the other 58 were done with bone-tendon-bone allografts. Additional procedures were performed on 180 of the patients. The interval from injury to reconstruction averaged 29 months. The protocol developed at our clinic employs a general anesthetic administered with the intent of same-day discharge, infiltration of the skin and joint with bupivacaine, a cold

Adverse events associated with medium- and long-term use of opioids for chronic non-cancer pain: an overview of Cochrane Reviews.

BACKGROUND: Chronic pain is common and can be challenging to manage. Despite increased utilisation of opioids, the safety and efficacy of lo … the equivalent milligrams of morphine per 24 hours for each opioid studied (buprenorphine, codeine, dextropropoxyphene, dihydrocodeine, fentanyl, hydromorphone, levorphanol, methadone, morphine, oxycodone, oxymorphone, tapentadol, tilidine, and tramadol). In the 14 Cochrane Reviews providing unique quantitative data, there were 61 studies with a total of 18,679 rand …

A randomized controlled trial to compare the efficacy of bisphosphonates in the management of painful bone metastasis.

IntroductionThe prospective interventional single-institution randomized control study was carried out to compare the pain relieving efficacy among different bisphosphonates at the cost of incidence of skeletal-related events (SRE).Materials and methodsDuring June 2008 and May 2011, 256 patients with painful bone metastasis in solid tumors with a pain score of at least 5 were randomized into three arms: zoledronic acid (4 mg, i.v.), ibandronate (6 mg, i.v.) and pamidronate (90 mg, i.v.). Radiation was given to all patients, either 800 cGy single fraction or 20 Gy in five fractions. The ANOVA t

Совпадение в полном тексте источника
… The narcotic score was calculated by multiplying pain medication [none = 0, analgesic = 1 (paracetamol, ibuprofen), mild narcotic = 2 (dextropropoxyphene), moderate narcotic =3 (tramadol) and strong narcotic = 4 (morphine)] and frequency of medication administration [none = 0, less than daily = 1 (p.r.n …

Oral non-steroidal anti-inflammatory drugs versus other oral analgesic agents for acute soft tissue injury.

BACKGROUND: Acute soft tissue injuries are common and costly. The best drug treatment for such injuries is not certain, although non-steroid … acetamol and an opioid. The applicability of findings from these studies is in question because the dextropropoxyphene combination analgesic agents used are no longer in general use. Very low-certainty evidence means we are uncertain of the findings of no differences between the two interventions in the numbers with little or no pain at day one (51 participants, 1 s …

Oral non-steroidal anti-inflammatory drugs versus other oral analgesic agents for acute soft tissue injury.

BACKGROUND: Acute soft tissue injuries are common and costly. The best drug treatment for such injuries is not certain, although non-steroid … l and an opioid. The applicability of findings from these studies is partly in question because the dextropropoxyphene combination analgesic agents used are no longer in general use. While the point estimates favoured NSAID, the very low-quality evidence did not show a difference between the two interventions in the numbers with little or no pain at day 1 (51 partic …

Распространение нетрофической боли в многоразовом склерозе - системном обзоре и мета-анализе с использованием алгоритма NeuPSIG.

Множественный склероз (MS) — нейродегенеративное расстройство, часто приводящее к нейропатической боли. Из-за нейродегенеративной природы диагноз нейропатической боли остается сложным. Была разработана система классификации, обеспечивающая обзор диагностической определенности (т.е. возможной, вероятной и определенной). Поскольку ни один из предыдущих обзоров не привел к этому, различия в диагностической определенности, возможно, повлияли на оценки распространенности. Чтобы прояснить этот вопрос, нынешний метаанализ был направлен на оценку распространенности возможной, вероятной и определенной

Совпадение в полном тексте источника
… ( 2018 ) | Cross sectional | 73 (34%/66%) | 1.49 ± 1.82 | 7.72 ± 3.97 | 63% RRMS | — 26% SPMS 11% CIS Moisset et al. ( 2013 ) | Cross sectional | 673 (20/80) | 3.7 ± 0.1 | 14.5 ± 0.4 | 74% RRMS | Paracetamol (45%) NSAID (14%) SAID (1%) Nefopam (0.6%) Tramadol (6%) Codeine (1%) Opium + Caffeine (2%) Dextropropoxyphene …

Prevention of suicide and attempted suicide in Denmark. Epidemiological studies of suicide and intervention studies in selected risk groups.

The suicide rates in Denmark have been declining during the last two decades. The decline was relatively larger among women than among men. All age groups experienced a decline except the very young with stable rates and the very old with increasing rates. The Universal, Selective, Indicated (USI) model recommended by Institute of Medicine was used as a framework for the thesis. Universal preventive interventions are directed toward the entire population; selective interventions are directed toward individuals who are at greater risk for suicidal behaviour; and indicated preventions are target

Neuropathic cancer pain: What we are dealing with? How to manage it?

Cancer pain is a serious health problem, and imposes a great burden on the lives of patients and their families. Pain can be associated with delay in treatment, denial of treatment, or failure of treatment. If the pain is not treated properly it may impair the quality of life. Neuropathic cancer pain (NCP) is one of the most complex phenomena among cancer pain syndromes. NCP may result from direct damage to nerves due to acute diagnostic/therapeutic interventions. Chronic NCP is the result of treatment complications or malignancy itself. Although the reason for pain is different in NCP and non

Совпадение в полном тексте источника
… Weak or short-acting opioids (eg, codeine, dihydrocodeine, and dextropropoxyphene), drugs with mixed effects (tramadol, tapentadol), and partial opioid agonists (transdermal buprenorphine) are advised if the result with nonopioid analgesics was not satisfactory. 9 , 92 There are some controversies about …

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