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Распространение остеопороза в хронических заболеваниях: зонтичный обзор 283 наблюдения, полученные в ходе 13 систематического обзора.

ВВЕДЕНИЕ: Остеопороз - это болезнь, характеризующаяся снижением плотности минералов кости и ухудшением микроархитектуры кости, что повышает риск разрушения. В контексте различных хронических патологий это состояние может привести к еще более высокому уровню заболеваемости, смертности и бремени здравоохранения. ЦЕЛЬ: Обобщать и сопоставлять имеющиеся данные, полученные в ходе систематических обзоров распространения остеопороза среди различных хронических заболеваний. МЕТОДОЛОГИЯ: В соответствии с руководящими принципами ПРИСМА был проведен зонтичный обзор с уделением особого внимания систематич

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… on T and Z scores or ICD-10 codes Moshayedi (2022) 57 227,812 Australia, Iran, Argentina, China, Germany, Tunisia, France, Thailand, Greece, Malaysia, South Korea, Kazakhstan, Romania, Italy, Pakistan, Mexico, India, Sweden, Turkey, Colombia, Ireland, United Kingdom, Norway, Brazil, United States, Morocco … Systematic review and meta-analysis Multiple Sclerosis Diagnosis based on clinical and radiological criteria Bone densitometry (DXA), T-score <= -2.5 Tu (2022) 22 1839 Canada, Brazil, India, Egypt, Italy, Spain, Greece, China, France, Turkey, Morocco, Hungary, Thailand, Iceland, Russia, Australia Patients …

Hematological malignancies in the Northwest Ethiopia.

BackgroundThe effect of malignant diseases is increasing globally, particularly in developing countries as shown by recent cancer statistics from the world health organization reports. It is anticipated that with an increase in life expectancy consequent upon the improved standard of living and increasing urbanization, the burden of hematological malignancies in sub-Saharan Africa particularly in Ethiopia is likely to increase recently. Therefore, this study was aimed to determine the incidence and trend of hematological malignancy in Northwest Ethiopia.MethodsA facility-based retrospective st

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… Similarly, it is lower than a study conducted in the USA, Canada, Chile, Morocco, South Africa, East Africa, Ethiopia, Addis Ababa, and Gondar showed that the prevalence of Leukemia among HM patients was 33.33%, 27%, 19.6%, 22.2%, 47.4%, 50.1%, 44.3%, and 30.2% respectively[ 16 – 18 , 21 – 24 , 26 ]. … Distribution and features of hematological malignancies in Eastern Morocco: a retrospective multicenter study over 5 years. BMC cancer. 2016. Dec 1;16(1):159. 23. Leak SA, Mmbaga L, Mkwizu EW, Mapendo PJ, Henke O. …

Post-traumatic diaphragmatic rupture with pericardial denudation: A case report.

INTRODUCTION: Post-traumatic diaphragmatic rupture is a lesion of variable severity. It is a rare and difficult to diagnose pathology, it ha … ial damage operated in the visceral emergency department at the Ibn Rochd Hospital c in Casablanca, Morocco.

Vaccines for preventing enterotoxigenic Escherichia coli (ETEC) diarrhoea.

BACKGROUND: Infection with enterotoxigenic Escherichia coli (ETEC) bacteria is a common cause of diarrhoea in adults and children in develop … aken in an endemic population in Bangladesh and one undertaken in people travelling from Finland to Morocco, evaluated a precursor of this vaccine containing purified cholera toxin B subunit rather than the recombinant subunit in Dukoral®. Short term protective efficacy against ETEC diarrhoea was demonstrated, lasting for around three months (RR 0.43, 95% …

Hypoglycemic and hypolipidemic effects of an aqueous extract of Chamaerops humilis leaves in obese, hyperglycemic and hyperlipidemic Meriones shawi rats.

An aqueous concoction made from the leaves of Chamaerops humilis (L.) (dwarf fan palm), is used in the Moroccan traditional medicine for the … this study validate the traditional use of the leaves of C. humilis in the treatment of diabetes in Morocco. Since, the aqueous leaf extract also decreased total cholesterol and triglycerides, the plant may also be useful in the management of secondary complications of diabetes (dyslipidemia). Furthermore, the plant may become a good source of antidiabeti …

Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria.

A known (1) and a structurally related new natural product (2), both belonging to the amorfrutin benzoic acid class, were isolated from the roots of Glycyrrhiza foetida. Compound 1 (amorfrutin B) is an efficient agonist of the nuclear peroxisome proliferator activated receptor (PPAR) gamma and of other PPAR subtypes. Compound 2 (amorfrutin C) showed comparably lower PPAR activation potential. Amorfrutin C exhibited striking antiproliferative effects for human colorectal cancer cells (HT-29 and T84), prostate cancer (PC-3), and breast cancer (MCF7) cells (IC50 values ranging from 8 to 16 μM in

Мельфаланский змеиный надвенный гиперпигментация с сопутствующим венозным тромбозом.

Serpentin suprevenus гиперпигментация (SSH) — редкая резиновая негативная реакция, характеризующаяся линейной гиперпигментацией вдоль поверхностных вен после внутривенной наркотерапии, чаще всего химиотерапией. Мы сообщаем о редком случае SSH, вызванном мелфаланом, который осложняется поверхностным венозным тромбозом. A 54-year-old человек, лечившийся от светоцепных миэломы, разработал асимптомные серпигинозные гиперпигированные повреждения вдоль поверхностной венозной сети one Через день после внутривенного инъекции мелфала до аутологической трансплантации стволовых клеток. Ten Через нескольк

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… Bouchra Baghad, Dermatology and venereology department, Ibn Rochd University Hospital Center, Hassan II University, 8 Rue Lahcen El Arjoun, Casablanca 20100, Morocco. … Hanane Rachadi, Dermatology and venereology department, Ibn Rochd University Hospital Center, Hassan II University, 8 Rue Lahcen El Arjoun, Casablanca 20100, Morocco. …

Клинические и гистологические модели и лечение пёдермы гангреносума.

Pyoderma gangrenosum (PG) является редким воспрещающим нейтрофильным дерматозом, в отношении которого точные эпидемиологические данные ограничены, а лечение по-прежнему является сложной задачей. Основная цель исследования состояла в том, чтобы изучить все случаи, когда в нашем департаменте было замечено, что 6-year - период для описания соответствующих характеристик и результатов лечения. Fourteen (Включены пациенты)5 женщины, 9 Мужчины). Средний возраст наших пациентов был 40,15 Годы. Классическая, язвительная форма была найдена в 10 в случаях71.42%), пастулярная форма в 4 в случаях27.57%) и

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… Methods We present a monocentric prospective, observational study included PG patients who were treated between 2009 and 2015 in the Department of Dermatology, University Hospital Hassan II, Fez, Morocco. … What this study adds The first study of PG in Morocco; Tuberculosis association with PG in our background. Competing interests The authors declare no competing interests. Authors’ contributions All the authors have read and agreed to the final manuscript. 1. …

Ten years of renal transplantation in a Moroccan hospital: results and constraints.

INTRODUCTION: Renal transplantation (RT) offers several advantages to end-stage renal disease (ESRD) patients, such as a better quality of life and economic benefits. This study sought to report a 10-year experience of RT in a developing country as well as the barriers to its improvement. PATIENTS AND METHODS: The retrospective study included 67 patients who underwent a first RT from a related living donor (RLD) between June 1998 and December 2008. We noted pretransplantation donor and recipient parameters as well as the results and barriers to RT promotion in our country. RESULTS: The mean

Cancer in the Oldest-Old Population in the MENA Region: Epidemiology and Temporal Trends Based on GBD 2021.

IntroductionCancer among the oldest-old (aged ≥85) is an escalating public health concern, particularly in the Middle East and North Africa (MENA), where demographic aging is advancing rapidly.MethodsWe analyzed cancer incidence and mortality trends among the oldest-old in MENA from 1990 to 2021 using Global Burden of Disease (GBD) 2021 data, and compared these trends to global patterns.ResultsCancer incidence and mortality among the oldest-old in MENA increased substantially, surpassing global trends. Between 1990 and 2021, incidence rose by 54.2% in MENA vs 25.3% globally, while mortality in

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… Stratification Based on the GBD 2021 The MENA region includes countries spanning two geographically and economically distinct areas: the Middle East (such as Lebanon, Jordan, Iraq, Saudi Arabia, and the Gulf Cooperation Council [GCC] countries) and North Africa (including Egypt, Libya, Tunisia, Algeria, Morocco … This region is characterized by substantial diversity in Socio-Demographic Index (SDI) levels, which reflect a population’s average achievements in income, education, and fertility, based on the GBD 2021 data. 20 , 21 MENA countries range from low SDI (Afghanistan, Yemen) and low-middle SDI (Egypt, Morocco …

Mapping Cancer in Africa: A Comprehensive and Comparable Characterization of 34 Cancer Types Using Estimates From GLOBOCAN 2020.

ObjectiveCancer incidence and mortality rates in Africa are increasing, yet their geographic distribution and determinants are incompletely characterized. The present study aims to establish the spatial epidemiology of cancer burden in Africa and delineate the association between cancer burden and the country-level socioeconomic status. The study also examines the forecasts of the cancer burden for 2040 and evaluates infrastructure availability across all African countries.MethodsThe estimates of age, sex, and country-specific incidence and mortality of 34 neoplasms in 54 African countries, we

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… All the countries in North Africa (Algeria, Egypt, Libya, Morocco, Sudan, and Tunisia) had greater ASIR and ASMR of breast cancer than cervical cancer ( Figures 1 , 2 ); reverse was true in majority sub-Saharan African countries ( Supplementary Figures 1 , 2 ). … Egypt, Nigeria, South Africa, Ethiopia, and Morocco had the highest incidence and mortality in 2020; these countries also account for 45% of cases and 44% of cancer deaths. La Reunion had the highest ASIR followed by South Africa, Zimbabwe, Namibia, Cabo Verde and Egypt. …

Cardiac amyloidosis: From diagnosis to therapeutics breakthroughs.

Cardiac amyloidosis (CA) is a progressive infiltrative cardiomyopathy resulting from the deposition of misfolded amyloid fibrils in the myocardium and heart valves, with the main forms being amyloid light-chain (AL), transthyretin-related (ATTR) (wild-type or hereditary), and amyloid A amyloidosis. Although historically underdiagnosed, recent advances in non-invasive imaging techniques such as cardiac magnetic resonance imaging and bone scintigraphy have significantly improved its recognition. This review outlines the current diagnostic approaches and therapeutic advancements in CA, emphasizin

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… Professor, India S-Editor: Liu H L-Editor: A P-Editor: Wang CH Contributor Information Maha Bouziane, Department of Cardiology, Ibn Rochd University Hospital of Casablanca, Casablanca 20000, Casablanca-Settat, Morocco. mahabouziane@gmail.com. … Omar Moufid, Department of Cardiology, Ibn Rochd University Hospital of Casablanca, Casablanca 20000, Casablanca-Settat, Morocco. Rachida Habbal, Department of Cardiology, Ibn Rochd University Hospital of Casablanca, Casablanca 20000, Casablanca-Settat, Morocco. References 1. Picken MM. …

Advances in Leukemia detection and classification: A Systematic review of AI and image processing techniques.

BACKGROUND: Leukemia, a heterogeneous group of blood cancers, poses significant challenges to global health due to its complexity, diverse risk factors, and variable outcomes. Accurate and early diagnosis is critical but remains a significant hurdle, particularly in low-resource settings. Recent advancements in artificial intelligence (AI) and image processing offer transformative solutions to improve leukemia detection and classification, addressing limitations in traditional diagnostic methods. METHODS: This study systematically reviewed over 25,000 scientific articles sourced from Scopus,

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… Comparatively, Morocco’s leukemia rates were lower than those in Tunisia and Algeria, and significantly lower than Western countries. … These findings emphasized the need for targeted genetic epidemiology studies and improved clinical management strategies. 8 Further, ElBakali, Abdellatif, and Smiri examined 8,851 cancer cases in the Souss Massa region of Morocco from 2014 to 2019. …

Common haematological malignancies in Northeastern Nigeria: a multi-centre study of their pattern, distribution and treatment challenges.

BackgroundHaematological malignancies (HMs) are primary cancers of the blood and blood-forming organs. They are heterogeneous and of diverse clinical features, treatment protocols and prognoses. They constitute a significant source of cancer-related morbidity and mortality. Northeastern Nigeria, being the region in the country with the worst literacy rate and poverty indices, is also battling with the burden of these diseases with the limited health facilities to adequately diagnose and treat these ailments. There is paucity of a comprehensive data on HMs in the region, so this study aims to r

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… This is similar to what was reported by Babatunde et al. and Errahhali et al., who respectively reported 8.1% and 9.3% cases of HMs in Ilorin, North Central Nigeria and Eastern Morocco ( 12 , 13 ). The age range of the study participants was between 6 months and 80 years. … This is similar to reports of HMs by Babatunde et al., Errahhali et al. and Akaba et al. in Ilorin Nigeria, Eastern Morocco and Calabar, south–south Nigeria, respectively ( 12 – 14 ). A contrasting result of female preponderance was reported by Perez et al. in Chile ( 15 ). …

Common polymorphic effectors of immunity against hepatitis B and C modulate susceptibility to infection and spontaneous clearance in a Moroccan population.

Chronic diseases caused by hepatitis B and C viruses may evolve towards major complications as liver cirrhosis and cancer. Fortunately, only subsets among acutely infected individuals develop a persistent disease suggesting that genetic susceptibility may influence the establishment of chronicity. In the present study we aim to explore variants distribution in genes encoding for important immune response effectors in chronic hepatitis B and C. We intend to identify common features and to establish connections between single nucleotide polymorphisms (SNPs) predisposing to both chronic hepatitis

Urban health: an example of a "health in all policies" approach in the context of SDGs implementation.

BACKGROUND: Cities are an important driving force to implement the Sustainable Development Goals (SDGs) and the New Urban Agenda. The SDGs p … ansit and Open Streets initiatives in several Latin American cities or targeted SDGs assessments in Morocco. CONCLUSIONS: By applying tools such as HIA, HiAP can be implemented to inform and improve transport and urban planning to achieve the 2030 SDG Agenda. Such a framework could be potentially used in cities worldwide, including those of less develope …

Injury burden among adolescents and young adults aged 10-24 years in the Arab region, 1990-2023: a systematic analysis of the Global Burden of Disease Study 2023.

BACKGROUND: Injuries are a leading cause of death and disability among adolescents and young people globally, but their burden has not been … ates: Algeria, Bahrain, Comoros, Djibouti, Egypt, Iraq, Jordan, Kuwait, Lebanon, Libya, Mauritania, Morocco, Oman, Palestine, Qatar, Saudi Arabia, Somalia, Sudan, Syria, Tunisia, the United Arab Emirates, and Yemen) from 1990 to 2023. We analysed mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years ( …

Barriers to the Provision and Utilization of Palliative Care in Africa: A Rapid Scoping Review.

Palliative care (PC) has continued to be less available, underutilized, and unintegrated in many of the healthcare systems, especially in Africa. This scoping review synthesized existing published papers on adult PC in Africa, to report the barriers to PC and to assess the methodologies used in these studies. Eight electronic databases and Google Scholar were searched to identify relevant studies published between 2005 and 2018. Overall, 42 publications (34 empirical studies and 9 reviews) that reported issues related to barriers to adult PC were selected. Three themes identified were individu

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… and South Africa were three out of 47 African countries that were consistently placed in the group of countries with a broad awareness of PC by healthcare professionals and local communities.[ 22 , 23 , 24 ] In contrast, 12 African countries (Botswana, Congo, Egypt, Malawi, Zambia, Zimbabwe, Nigeria, Morocco … The finding from the 2015 QOD index showed that many African countries belonged to the category of countries that had a shortage of specialized PC professionals, with the exception of countries such as Uganda, Morocco, and Egypt, which had specialized PC professionals, although specialist PC training …

Surgical Management of Multiple Myeloma With Symptomatic Involvement of the Spine.

INTRODUCTION: Fistulizing Crohn's disease is a severe phenotype of inflammatory bowel disease and may be complicated by enterocutaneous fistulas, which are associated with substantial morbidity due to sepsis, fluid and electrolyte disturbances, skin damage, and severe malnutrition. Anti-tumour necrosis factor agents, particularly infliximab, represent a cornerstone of medical therapy for fistulizing Crohn's disease. However, their initiation may need to be temporarily deferred in patients with septic risk, uncontrolled fistula output, or profound nutritional impairment. CASE REPORT: We report

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… FISTULA: A CASE REPORT AND LITERATURE REVIEW Essadi Btissam , Benderrou Mouhssine, Ouiam Elmqaddem, Hajar Koulali, Abdelkrim Zazour, Zahi Ismaili, Ghizlane Kharrasse (LAPOD) Research Laboratory of Pathology and Digestive Oncology, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco … Department of Hepato-Gastroenterology, Mohammed VI University Hospital Center, Oujda, Morocco Corresponding author’s e-mail: btissamfg.1995@gmail.com Received: 30/05/2026 Accepted: 22/06/2026 Published: 15/07/2026 Conflicts of Interests: The Authors declare that there are no competing interests. …

Models of care for children and adolescents with type 1 diabetes in low- and middle-income countries: a scoping review.

BACKGROUND: In order to improve the outcomes of children and adolescents with type 1 diabetes mellitus (T1DM), access to and quality of comp … ng certain supplies and technologies. Eastern Mediterranean Region We identified a model of care in Morocco, implemented in 1986, that had expanded from a single tertiary-level facility to nine provincial secondary-level hospitals, covering a third of the country's young patients with T1DM. Care was delivered by multidisciplinary teams and included initia …